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Continued evidence for safety of endoscopic retrograde cholangiopancreatography during pregnancy

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World Journal of Gastrointestinal Endoscopy 2014年第8期6卷 352-358页

作者： sean fine Joshua Beirne Silvia Delgi-Esposti Fadlallah Habr Department of Internal Medicine Warren Alpert School of Medicine Brown University Providence RI 02903 United States Department of Gastroenterology Santa Rosa Memorial Hospital and Sutter Medical Center Santa Rosa CA 95404 United States Department of Gastroenterology Warren Alpert School of Medicine Brown University Providence RI 02903 United States

AIM: To report the safety of continued use of endoscopic retrograde cholangiopancreatography(ERCP) during pregnancy at various maternal ***: A retrospective chart review of pregnant patients who underwent ERCP at a tertiary academic center was undertaken between 2002 and 2012. Pertinent past medical history and initial presenting laboratory data were collected. Review of the procedure note for each ERCP performed provided documentation of lead shielding, type of sedation, fluoroscopy time, and post-procedure complications. Patients' clinical courses were reviewed until the time of delivery and pregnancy complications with fetal outcomes were examined. Data was stratified based upon the mother's age at the time of ERCP: 18-21, 22-29, and ≥ 30 years of ***: Twenty pregnant patients who underwent ERCP between 2002 and 2012 were identified. The mean age at the time of ERCP was 26.4 years(18-38 years) and the average trimester was the second. The indications for ERCP were choledocholithiasis in 17 patients, gallstone pancreatitis in 2 patients, and cholangitis in 1 patient. The mean fluoroscopy time of ERCP was 3.8 min(0.3-23.6 min). Sphincterotomy was performed in 18 patients with therapeutic intent and not as a prophylactic measure to prevent recurrences. Clinical documentation of use of protective shielding was found in only 8 notes(40%). Post procedure complications were limited to two cases of post-ERCP pancreatitis(10%). Elective cholecystectomy was performed shortly after ERCP in 11 of the pregnant patients. Birth records were available for 16 patients, of which 15 had fullterm pregnancies. Cesarean sections were performed in 5(31%) patients. Term birth weight was greater than 2500 g in all cases except one in which the mother had a known hypercoagulable state. CONCLUSION: ERCP during pregnancy is both safe and efficacious regardless of maternal age or trimester.

关键词： Endoscopic retrograde cholangiopancreatography Pregnancy Choledocholithiasis Pancreatitis Cholecystectomy Caesarean section

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混凝土基本组分吸收二氧化碳的能力(英文)

硅酸盐学报 2010年第9期38卷 1645-1651页

作者：邵一心 MONKMAN sean TRAN Stanley McGill University Department of Civil Engineering

研究了利用混凝土产品吸收二氧化碳的可行性。混凝土的3个基本组分:水泥、细沙和骨料,都可被用来作为二氧化碳吸附物以实现储留最大化,另外,可利用高钙钢渣等工业废料生产混凝土骨料。研究发现波特兰水泥2h碳化后吸收14%二氧化碳,碳化... 详细信息

研究了利用混凝土产品吸收二氧化碳的可行性。混凝土的3个基本组分:水泥、细沙和骨料,都可被用来作为二氧化碳吸附物以实现储留最大化,另外,可利用高钙钢渣等工业废料生产混凝土骨料。研究发现波特兰水泥2h碳化后吸收14%二氧化碳,碳化后的材料的强度与7d传统养护的强度相当。钢包钢渣细粉能吸收4%～12%二氧化碳,能用来替代河沙。吹氧高炉钢渣对二氧化碳吸收的能力超过12%。由此制成的粗骨料其强度可与石灰岩相比。如果混凝土砌块由这3组分组成,一块20cm×20cm×20cm的标准砌块能吸收1.39kg二氧化碳。二氧化碳在混凝土中的储留是一项经济可行、直接减排的有效技术。

关键词：二氧化碳养护混凝土砌块钢渣骨料强度减排二氧化碳储留

Inferring truck activities using privacy-preserving truck trajectories data

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Journal of Intelligent and Connected Vehicles

Journal of Intelligent and Connected Vehicles 2023年第1期6卷 16-33页

作者： Arnav Choudhry sean Qian Carnegie Mellon University Pittsburgh PA 15213USA

Global Navigation Satellite System(GNSS)data is an inexpensive and ubiquitous source of activity *** Positioning System(GPS)is an example of such *** there have been several studies about inferring device activity using GPS data from a consumer device,freight GPS data presents unique challenges for example having low and variable frequency,long transmission gaps,and frequent and unpredictable device ID resetting for preserving *** study aims to provide an end-to-end,generic data analytical framework to infer multiple aspects of truck activity such as stops,trips,and *** use popular existing methods to construct the data processing pipeline and provide insights into their practical *** also propose improved data filters to different aspects of the data processing pipeline to address challenges found in privacy-preserving freight GPS *** use freight data across four weeks from the greater Philadelphia region with variable transmission frequency ranging from one second to several hours to perform experiments and validate our *** findings indicate that auxiliary information such as land use can be helpful in fine tuning stop inference,but spatio-temporal information contained in timestamped GPS pings is still the most powerful source of false stop *** also find that a combination of simple clustering techniques can provide a way to perform fast and reasonable clustering of the same stop.

关键词： freight activity GPS processing stop detection freight privacy tour inference

The Development of a Simulated Sediment Dosing Apparatus for Deposition Research in Wastewater Collection Systems

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Journal of Water Resource and Protection 2018年第5期10卷 493-506页

作者： David Campbell sean Mushin Craig Saunders Water Academy Heriot Watt University Riccarton Scotland Heriot Watt University Riccarton Scotland School of the Built Environment Heriot Watt University Riccarton Scotland

Water conservation initiatives promote installation of water efficient and low-flow appliances in waste water collection systems. This has resulted in lower flow rates in those systems than the intended design loading, causing solid deposition and sedimentation in some areas. A joint UKWIR/EPSRC CASE grant (14440031) has funded the work described in this paper which investigates sedimentation and solid deposition in building drainage system pipes. The purpose of this paper is to detail the design, calibration and operation of a sediment dosing apparatus to simulate sedimentation rates and explore possible solutions to this issue with a full scale laboratory model based on real site data. The methodology adopted is an experimental approach, where tests have been conducted on the sediment dosing apparatus based on calculations and observations to determine an appropriate sediment dosing regime representative of typical systems. Further tests were conducted with the addition of everyday household products to investigate their effects on sedimentation. The results indicated that a suitable dosing rate was approximately 12% weight-to-volume (w/v) of a fine sand with a known particle size distribution, diluted 1:5 in a clean water base flow. It was also shown that the addition of the household products added to the problem of sedimentation within drainage systems. The results give excellent correlation to real site data, with deposition depth and distribution comparable to measured site data to within 10%. The deposition was achieved within three hours, which approximated six weeks deposition in the live site used in the study. This straightforward investigation details the design, construction and testing of a device to cause accelerated sedimentation in a full scale model of a building drainage system. This is the first step in the process of updating research underpinning our understanding of the behaviour of these systems under conditions of low flow rates caused by w

关键词： Water Conservation Deposition Modelling Computer Simulation Empirical Model Site Sampling

Mathematical Modeling in Social Network Analysis： Using TOPSIS to Find Node Influences in a Social Network

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Journal of Mathematics and System Science 2013年第10期3卷 531-541页

作者： William P Fox sean F. Everton Department of Defense Analysis Naval Postgraduate School Monterey CA 93943 USA

In a social network analysis the output provided includes many measures and metrics. For each of these measures and metric, the output provides the ability to obtain a rank ordering of the nodes in terms of these measures. We might use this information in decision making concerning disrupting or deceiving a given network. All is fine when all the measures indicate the same node as the key or influential node. What happens when the measures indicate different key nodes？ Our goal in this paper is to explore two methodologies to identify the key players or nodes in a given network. We apply TOPSIS to analyze these outputs to find the most influential nodes as a function of the decision makers＇ inputs as a process to consider both subjective and objectives inputs through pairwise comparison matrices. We illustrate our results using two common networks from the literature： the Kite network and the Information flow network from Knoke and Wood. We discuss some basic sensitivity analysis can may be applied to the methods. We find the use of TOPSIS as a flexible method to weight the criterion based upon the decision makers＇ inputs or the topology of the network.

关键词： Social network analysis multi-attribute decision making Analytical hierarchy process (AHP) weighted criterion TOPSIS node influence

粘土矿物参与微生物利用木质素形成矿物-菌体残留物的结构特征研究

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光谱学与光谱分析 2018年第9期38卷 2903-2909页

作者：王帅徐俊平陈殿元姜帅李兴吉盛炳翰 Schaeffer sean 吉林农业科技学院农学院吉林吉林132101 Institute of Agricalture The University of Tennessee

粘土矿物在催化木质素形成腐殖质方面具有重要贡献。为有效阐明微生物-木质素-粘土矿物三者间的关系,探明矿物-菌体残留物的结构特征,采用液体摇瓶培养法,以木质素为碳源,通过添加高岭石和蒙脱石,在接种复合菌剂后启动110d液体培养,期... 详细信息

粘土矿物在催化木质素形成腐殖质方面具有重要贡献。为有效阐明微生物-木质素-粘土矿物三者间的关系,探明矿物-菌体残留物的结构特征,采用液体摇瓶培养法,以木质素为碳源,通过添加高岭石和蒙脱石,在接种复合菌剂后启动110d液体培养,期间动态收集矿物-菌体残留物,利用傅里叶红外光谱及扫描电子显微镜技术对其结构特性进行了研究。结果表明:高岭石颗粒边缘多由管状体卷曲而成,在参与微生物利用木质素形成矿物-菌体残留物后,连片状细小颗粒结构进一步团聚,结合更加紧凑,短管状结构增多,但整体仍保持多水高岭石的结构特征;在初始富营养条件下,高岭石能够促进微生物繁衍,使大量菌体聚集于高岭石表面,掩蔽了Si—O和Si—O—Al键,且矿物-菌体残留物中脂族碳结构比例增加;菌体中多糖物质通过含氧官能团与高岭石表面的水化层在多个部位形成氢键,氢键的形成对于高岭石稳定木质素及其降解产物具有重要作用,芳香碳结构比例和多糖类物质含量随培养时间逐渐增加,而后复合菌株对掩蔽在矿物表面的菌体进行二次利用,使高岭石Si—O—Al键重现;蒙脱石多由浑圆的颗粒结构组成,接种微生物可使其表面产生溶蚀,团粒结构遭到破碎;与10d相比,历经30d培养所得矿物-菌体残留物中的多糖类物质增多,使原本归属蒙脱石Si—O—Si及Si—O结构的1 034~1 038cm-1处吸收峰强度增加,而后因多糖类物质与蒙脱石表面羟基发生缔合,又使该处吸收峰强度减弱,同时发生了氢键键合,该作用是蒙脱石-微生物-木质素间相互作用、形成矿物-菌体残留物的主要机制;高岭石在稳定有机碳方面的能力要高于蒙脱石,更易促进HS前体物质的形成。

关键词：傅里叶红外光谱扫描电子显微镜粘土矿物木质素矿物-菌体残留物

In vivo performance of a rare earth free Mg-Zn-Ca alloy manufactured using twin roll casting for potential applications in the cranial and maxillofacial fixation devices

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Bioactive Materials 2022年第6期7卷 85-96页

作者： Matthew S.Dargusch Nagasivamuni Balasubramani Nan Yang sean Johnston Yahia Ali Gui Wang Jeffrey Venezuela Jiwon Carluccio Cora Lau Rachel Allavena Daniel Liang Karine Mardon Qingsong Ye Centre for Advanced Materials Processing and Manufacturing(AMPAM) School of Mechanical and Mining EngineeringThe University of QueenslandBrisbaneQLD 4072Australia The University of Queensland Biological ResourcesBrisbaneQLD4072Australia School of Veterinary Science The University of QueenslandGattonQLD4343Australia Commonwealth Scientific and Industrial Research Organisation(CSIRO) ClaytonMelbourneAustralia Centre for Advanced Imaging National Imaging FacilityThe University of QueenslandSt LuciaBrisbaneQLD4072Australia Centre of Regenerative Medicine Renmin Hospital of Wuhan UniversityWuhan UniversityWuhanWuhan430060China Skeletal Biology Research Centre Department of Oral and Maxillofacial SurgeryMassachusetts General HospitalHarvard School of Dental MedicineBostonMA02114United States

A magnesium alloy containing essential,non-toxic,biodegradable elements such as Ca and Zn has been fabricated using a novel twin-roll casting process(TRC).Microstructure,mechanical properties,in vivo corrosion and biocompatibility have been assessed and compared to the properties of the rare earth(RE)element containing WE43 *** Mg-0.5 wt% Zn-0.5 wt% Ca exhibited fine grains with an average grain size ranging from 70 to 150μ*** properties of a TRC Mg-0.5Zn-0.5Ca alloy showed an ultimate tensile strength of 220 MPa and ductility of 9.3%.The TRC Mg-0.5Zn-0.5Ca alloy showed a degradation rate of 0.51±0.07 mm/y similar to that of the WE43 alloy(0.47±0.09 mm/y)in the rat model after 1 week of *** week 4 the biodegradation rates of both alloys studied were lowered and stabilized with fewer gas pockets around the *** histological analysis shows that both WE43 and TRC Mg-0.5Zn-0.5Ca alloy triggered comparable tissue healing responses at respective times of *** presence of more organized scarring tissue around the TRC Mg-0.5Zn-0.5Ca alloys suggests that the biodegradation of the RE-free alloy may be more conducive to the tissue proliferation and remodelling process.

关键词： Mg-Zn-Ca alloy Twin-roll strip casting In vivo degradation Biocompatibility Biodegradable implants

Lewis碱催化的α-胺基腈及氰醇的烯丙基官能团化反应研究及应用

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有机化学 2014年第11期34卷 2187-2194页

作者：秦天游张晓安寮渭巍大连理工大学精细化工国家重点实验室大连116024 吉林大学化学学院长春130012

对我们研究小组近几年在Lewis碱催化具有α-位氢的α-胺基腈类及氰醇类化合物与Morita-Baylis-Hillman(MBH)加合物立体选择性的烯丙基化反应方面取得的初步成果进行了小结.通过与MBH加合物的烯丙基取代反应,有效地构建了具有α-位季碳... 详细信息

对我们研究小组近几年在Lewis碱催化具有α-位氢的α-胺基腈类及氰醇类化合物与Morita-Baylis-Hillman(MBH)加合物立体选择性的烯丙基化反应方面取得的初步成果进行了小结.通过与MBH加合物的烯丙基取代反应,有效地构建了具有α-位季碳结构单元的多官能团腈类衍生物,而且基于此发展了一类非金属催化的烯烃分子内氰官能团化反应,构建了β-位有季碳结构单元的官能团化的腈类化合物.此外对影响反应的可能因素也做了讨论,提出了可能的反应机理.

关键词：烯丙基化路易斯碱催化 α-胺基腈氰醇碳氰化反应

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2000年全球表面活性剂和洗涤剂综述

精细石油化工进展 2001年第5期2卷 52-54页

作者： sean Milmo Helean Harvilicz 郑薇

1　寻求表面活性剂利润回升　　原料成本上升是商品表面活性剂生产者面对的主要问题。1999年末，许多大的表面活性剂生产者宣称提高商品表面活性剂的价格，但上升的原料价格侵害了表面活性剂价格上升回收的毛利润。特别是LAB价格上升使... 详细信息

1　寻求表面活性剂利润回升　　原料成本上升是商品表面活性剂生产者面对的主要问题。1999年末，许多大的表面活性剂生产者宣称提高商品表面活性剂的价格，但上升的原料价格侵害了表面活性剂价格上升回收的毛利润。特别是LAB价格上升使主要洗涤剂表面活性剂LAS受到压力。油化学品和乙烯价格上升影响了脂肪醇硫酸盐和脂肪醇醚硫酸盐。

关键词： 2000年世界表面活性剂洗涤剂综述