检索结果-南通市图书馆

Parallelization of frequency domain quantum gates:manipulation and distribution of frequency-entangled photon pairs generated by a 21 GHz silicon microresonator

在线全文

学校读者我要写书评

暂无评论

Advanced Photonics 2024年第3期6卷 60-69页

作者： Antoine henry dario A.Fioretto Lorenzo M.Procopio Stéphane Monfray Frédéric Boeuf Laurent Vivien Eric Cassan Carlos Alonzo-Ramos Kamel Bencheikh Isabelle Zaquine Nadia Belabas Institut Polytechnique de Paris LTCITélécom ParisPalaiseauFrance Université Paris-Saclay CNRSCentre for Nanosciences and NanotechnologyUMR 9001PalaiseauFrance Weizmann Institute of Science RehovotIsrael STMicroelectronics SAS CrollesFrance

Harnessing the frequency dimension in integrated photonics offers key advantages in terms of scalability,noise resilience,parallelization,and compatibility with telecom multiplexing *** ring resonators have been used to generate frequency-entangled states through spontaneous four-wave ***,state-of-the-art integrated resonators are limited by trade-offs among size,spectral separation,and efficient photon pair *** have developed silicon ring resonators with a footprint below 0.05 mm^(2)providing more than 70 frequency channels separated by 21 *** exploit the narrow frequency separation to parallelize and independently control 34 single qubit-gates with a single set of three off-the-shelf electro-optic *** fully characterize 17 frequency-bin maximally entangled qubit pairs by performing quantum state *** demonstrate for the first time,we believe,a fully connected five-user quantum network in the frequency *** results are a step towards a generation of quantum circuits implemented with scalable silicon photonics technology,for applications in quantum computing and secure communications.

关键词： integrated photonics frequency domain quantum gates quantum networks

The magnetosheath at high spectral resolution

在线全文

学校读者我要写书评

暂无评论

Earth and Planetary Physics 2024年第1期8卷 234-246页

作者： K.d.Küntz d.Koutroumpa W.R.dunn A.Foster F.S.Porter d.G.Sibeck B.Walsh The henry A.Rowland department of Physics and Astronomy Johns Hopkins University3701 San Martin DriveBaltimoreMD21218USA NASA Goddard Space Flight Center 8800 Greenbelt RoadGreenbeltMD 20771USA LATMOS-OVSQ CNRSUVSQ Paris-SaclaySorbonne Université11 Boulevard d’Alembert78280GuyancourtFrance department of Physics and Astronomy University College LondonLondonUK The Centre for Planetary Science at UCL/Birkbeck Gower StreetLondon WC1E 6BTUK Center for Astrophysics Harvard University&Smithsonian Institution60 Garden StreetCambridgeMA 02138USA Center for Space Physics Boston University110 Cummington MallBostonMAUSA

While we eagerly anticipate SMILE’s(Solar wind Magnetosphere Ionosphere Link Explorer)unprecedented X-ray observations of the Earth’s magnetosheath and the initiation of a new era of magnetospheric research,it seems appropriate to look ahead to the abilities of the next generation of astrophysics *** these,the Line Emission Mapper(LEM),a large aperture micro-calorimeter based mission,is currently planned to be able to observe the magnetosheath at high spectral resolution(~2 eV).With a field of view of~30′,LEM will allow higher spatial resolution and higher cadence measurement of the motion of a very small portion of the magnetopause over relatively short periods of time(multiple hours),complementing SMILE’s global ***’s strength is its spectral *** will be able to measure the abundance of a broad range of elements and ionization states,many of which are inaccessible to current in situ instruments,and will be able to separate the emission from the magnetosheath from the emission from the cosmic X-ray background using the difference in their relative velocities.

关键词： magnetosheath charge exchange solar wind abundances

New therapeutic opportunities for Hepatitis C based on small RNA

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第33期13卷 4431-4436页

作者： Qiu-wei Pan scot.d.henry Bob J Scholte Hugo W Tilanus Harry LA Janssen Luc JW van der Laan departments of Gastroenterology & Hepatology and Surgery Erasmus MC-University Medical Centre Rotterdam The Netherlands department of Surgery Erasmus MC-University Medical Centre Rotterdam The Netherlands department of Cell Biology Erasmus MC- University Medical Centre Rotterdam The Netherlands department of Gastroenterology & Hepatology Erasmus MC-University Medical Centre Rotterdam The Netherlands

Hepatitis C virus （HCV） infection is one of the major causes of chronic liver disease, including cirrhosis and liver cancer and is therefore, the most common indication for liver transplantation. Conventional antiviral drugs such as pegylated interferon-alpha, taken in combination with ribavirin, represent a milestone in the therapy of this disease. However, due to different viral and host factors, clinical success can be achieved only in approximately half of patients, making urgent the requirement of exploiting alternative approaches for HCV therapy. Fortunately, recent advances in the understanding of HCV viral replication and host cell interactions have opened new possibilities for therapeutic intervention. The most recent technologies, such as small interference RNA mediated gene-silencing, antisense oligonucleotides （ASO）, or viral vector based gene delivery systems, have paved the way to develop novel therapeutic modalities for HCV. In this review, we outline the application of these technologies in the context of HCV therapy. In particular, we will focus on the newly defined role of cellular microRNA （miR-222） in viral replication and discuss its potential for HCV molecular therapy.

关键词： Hepatitis C virus therapy miR-122 RNAi Antisense oligonucleotides Viral vectors

Genomic Profile of SARS-COV-2 Associated with COVId-19 Outbreaks in N’djamena, Chad

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Bioscience and Biotechnology 2024年第7期15卷 432-442页

作者： Mathieu Hota henry Yandai Fissou dezoumbe Koutaya djallaye djimtoïbaye Mahamat Moussa Ali cole doctorale Sciences Techniques et Environnement Universit de NDjamena NDjamena Tchad Institut de Recherche en Elevage pour le dveloppement NDjamena Tchad Laboratoire des Grandes pidmies Tropicales du CHU le Bon Samaritain NDjamena Tchad Facult des Sciences de la Sant Humaine (FSSH) Universit de NDjamena NDjamena Tchad

Background: SARS-CoV-2 has circulated worldwide with dramatic consequences. In Chad, we have no data reported of variants. The aim of this study was to identify the SARS-CoV-2 variants that circulated during the epidemic from 2020 to 2021. Methods: This is a cross-sectional, descriptive study carried out between 2020 and 2021. Samples from patients with suspected COVId-19 were tested in five laboratories in N’djamena. One hundred quality samples of the positives were sequenced in Kinshasa using Oxford nanopore technologies minion and the Protocol Midnight SARS-CoV2. data were processed using Excel version 16 software. Results: Of the 100 samples sequenced, 77 (77%) produced sequences, 23 (23%) did not. The genomic profiles were wild-type Wuhan and minor mutations (19A, 19B (A), 20A (B.1, B.2), 20B (AV.1), 20d (B.1.1.1 /C.36), 20C), variant of concern Alpha (20I), variant of concern delta (21A/J), variant of interest Eta (21d), variant of concern Omicron (21K) and unclassified variant under surveillance (B.1.640). Of these variants, the maximums were detected in patients aged 26 - 35 with 30.26% and 25.26% in 36 - 45. However, 24.67% were in travelers and 75.32% in residents, 35.06% in those vaccinated against COVId-19 and 62.33% in non-vaccinates. The estimated case-fatality rate was 2.44% (107/4374). Conclusion: This work has provided preliminary data on COVId-19 and SARS-CoV-2 variants circulating during the 2020-2021 epidemics in Chad.

关键词： COVId-19 SARS-CoV-2 Genomic Profile Variant Chad

Results of selective decontamination with oral neomycin and metronidazole for major colorectal surgery in Australia:A cohort study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Laparoscopic, Endoscopic and Robotic Surgery 2024年第2期7卷 72-78页

作者： James Wei Tatt Toh devansh Shah henry Wang Charlotte Kwik Joseph do Woong Choi Chelsie Leonie Beinke Paul Morris Eleni Baird-Gunning Geoffrey Peter Collins Fiona Gavegan Karen Shedden Toufic El-Khoury Nimalan Pathma-Nathan Kerry Hitos department of Colorectal Surgery Westmead HospitalWestmeadNew South WalesAustralia The University of Sydney Westmead HospitalWestmeadNew South WalesAustralia Western Sydney University New South WalesAustralia University of Notre dame New South WalesAustralia Westmead Research Centre for Evaluation of Surgical Outcomes Westmead HospitalSydneyAustralia

Objective The role of selective decontamination with oral antibiotics(OABs)and mechanical bowel preparation(MBP)prior to elective colorectal surgery is still widely *** objective of this study was to compare the outcomes of selective decontamination with neomycin,metronidazole and MBP compared to those of decontamination with MBP alone or with no *** Selective decontamination with neomycin and metronidazole combined with bowel preparation was introduced prior to elective colorectal surgery as part of an enhanced recovery after surgery program at Westmead Hospital,a major Australian tertiary referral hospital,between June 2017 and January *** between short-term outcomes of OAB+MBP and MBP/no preparation were made using prospectively collected data on length of stay(LOS),readmission,mortality within 30 days,anastomotic leakage(AL),surgical site infection(SSI),urinary tract infection,deep venous thrombosis and/or pulmonary embolism,pneumonia,and ***-up was limited to hospital stays and subsequent presentations within the health district within thirty days of *** Mann-Whitney U test was used to analyse continuous data,and the chi-square test was used for categorical *** and multivariate regression modelling was performed to identify risk factors associated with an increased likelihood of SSI and *** Patients with oral neomycin and metronidazole combined with bowel preparation had reduced superficial SSI(2.7%vs.7.6%,p=0.043)and overall complications(32.7%vs.44.6%,p=0.020),particularly Clavien-dindo 1 complications(7.3%vs.16.5%,p=0.009).However,the differences in AL(2.7%vs.4.5%,p=0.369)and organ/space SSI(1.3%vs.3.7%,p=0.327)were not statistically *** median LOS(6 d vs.6 d,p=0.370)was not different between the *** Selective decontamination with neomycin and metronidazole reduces the risk of SSIs and overall *** was a trend to toward a lower AL,but this differ

关键词： Neomycin Metronidazole Colorectal surgery Anastomotic leakage Surgical site infection

Transient growth in Poiseuille-Rayleigh-Bénard flows of binary fluids with Soret effect

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2016年第9期37卷 1203-1218页

作者： Jun HU d.henry H.BENHAdId Xieyuan YIN Institute of Applied Physics and Computational Mathematics Beijing 100088China Laboratoire de Mecanique des Fluides et d'Acoustique CNRS/Universitd de LyonEcole Centrale de Lyon/universite Lyon 1/INSA de LyonECL36 avenue Guy de Collongue69134 Ecully CedexFrance department of Modern Mechanics University of Science and Technology of ChinaHefei 230027China

The transient growth due to non-normMity is investigated for the Poiseuille- Rayleigh-Benard problem of binary fluids with the Soret effect. For negative separation factors such as ψ = -0.1, it is found that a large transient growth can be obtained by the non-normal interaction of the two least-stable-modes, i.e., the upstream and downstream modes, which determine the linear critical boundary curves for small Reynolds numbers. The transient growth is so strong that the optimal energy amplification factor G（t） is up to 10^2 - 10^3. While for positive separation factors such as ψ = 0.1, the transient growth is weak with the order O（I） of the amplification factor, which can even be computed by the least-stable-mode. However, for both cases, the least-stable-mode can govern the long-term behavior of the amplification factor for large time. The results also show that large Reynolds numbers have stabilization effects for the maximum amplification within moderate wave number regions. Meanwhile, much small negative or large positive separation factors and large Rayleigh numbers can enlarge the maximum transient growth of the pure streamwise disturbance with the wavenumber α= 3.14. Moreover, the initial and evolutionary two-dimensional spatial patterns of the large transient growth for the pure streamwise disturbance are exhibited with a plot of the velocity vector, spanwise vorticity, temperature, and concentration field. The initial three-layer cell vorticity struc- ture is revealed. When the amplification factor reaches the maximum Gmax, it develops into one cell structure with large amplification for the vorticity strength.

关键词： binary fluid Soret effect transient growth Poiseuille-Rayleigh-Benard flow

Using machine learning and a data-driven approach to identify the small fatigue crack driving force in polycrystalline materials

在线全文

学校读者我要写书评

暂无评论

npj Computational Materials 2018年第1期4卷 363-372页

作者： Andrea Rovinelli Michael d.Sangid henry Proudhon Wolfgang Ludwig School of Aeronautics and Astronautics Purdue University701W.Stadium AveWest LafayetteIN 47907USA MINES ParisTech PSL Research UniversityMAT-Centre des matériauxCNRS UMR 7633BP 8791003 EvryFrance University of Lyon INSA LyonMATEISUMR 5510 CNRSF-69621 LYONFrance

The propagation of small cracks contributes to the majority of the fatigue lifetime for structural *** significant interest,criteria for the growth of small cracks,in terms of the direction and speed of crack advancement,have not yet been *** this work,a new approach to identify the microstructurally small fatigue crack driving force is *** network and machine learning techniques are utilized to identify relevant micromechanical and microstructural variables that influence the direction and rate of the fatigue crack propagation.A multimodal dataset,combining results from a high-resolution 4d experiment of a small crack propagating in situ within a polycrystalline aggregate and crystal plasticity simulations,is used to provide training *** relevant variables form the basis for analytical expressions thus representing the small crack driving force in terms of a direction and a rate *** ability of the proposed expressions to capture the observed experimental behavior is quantified and compared to the results directly from the Bayesian network and from fatigue metrics that are common in the *** indicate that the direction of small crack propagation can be reliably predicted using the proposed analytical model and compares more favorably than other fatigue metrics.

关键词： fatigue crack driving

Influences of load carriage and physical activity history on tibia bone strain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2019年第5期8卷 478-485页

作者： henry Wang Mohammad Kia d.Clark dickin Biomechanics Laboratory School of KinesiologyBall State UniversityMuncieIN 47306USA department of Biomechanics Hospital for Special SurgeryNew YorkNY 10021USA

Background:Military recruits are often afflicted with stress *** military’s strenuous training programs involving load carriage may contribute to the high incidence of tibia stress fractures in the *** purpose of this study was to assess the influences of incremented load carriage and history of physical activity on tibia bone strain and strain rate during ***:Twenty recreational basketball players and 20 recreational runners performed 4 walking tasks while carrying 0 kg,15 kg,25 kg,and35 kg loads,*** bone strain and strain rate were obtained through subject-specific multibody dynamic simulations and finite element *** model repeated-measures analyses of variance were ***:The mean±SE of the runners’ bone strain(μs)during load carriages(0 kg,15 kg,25 kg,and 35 kg)were 658.11±1.61,804.41±1.96,924.49±2.23,and 1011.15±2.71,respectively,in compression and 458.33±1.45,562.11±1.81,669.82±2.05,and 733.40±2.52,respectively,in *** the basketball players,the incremented load carriages resulted in compressive strain of 634.30±1.56,746.87±1.90,842.18±2.16,and 958.24±2.63,respectively,and tensile strain of 440.04±1.41,518.86±1.75,597.63±1.99,and 700.15±2.47,respectively.A dose-response relationship exists between incremented load carriage and bone strain and strain rate.A history of regular basketball activity could result in reduced bone strain and reduced strain ***:Load carriage is a risk factor for tibia stress fracture during basic *** exercise programs,such as basketball,that involved multidirectional mechanical loading to the tibia bones can be implemented for military recruits before basic training commences.

关键词： Modeling Multi-body dynamics Strain Strain rate Stress fracture Walking

Hepatic lipogranulomas in patients with chronic liver disease: Association with hepatitis C and fatty liver disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第40期16卷 5065-5069页

作者： Hongfa Zhu henry C Bodenheimer david J Clain Albert d Min Neil d Theise department of Pathology Mount Sinai School of MedicineNewYorkNY10029United States department of Medicine (divisions of digestive diseases)Beth Israel Medical Center Albert Einstein College of Medicine department of Pathology Beth Israel Medical CenterAlbert Einste in College of MedicineNew YorkNY 10003United States

AIM: To study the significance and clinical implication of hepatic lipogranuloma in chronic liver diseases, including fatty liver disease and hepatitis C. METHOdS: A total of 376 sequential, archival liver biopsy specimens were reviewed. Lipogranuloma, steatosis and steato-fibrosis were evaluated with combined hematoxylin and eosin and Masson’s trichrome staining. RESULTS: Fifty-eight (15.4%) patients had lipogranuloma, including 46 patients with hepatitis C, 14 patients with fatty liver disease, and 5 patients with other diseases. Hepatic lipogranuloma was more frequently seen in patients with hepatitis C (21%) and fatty liver disease (18%), and its incidence was significantly higher than that in control group (P d P ddition, 39 out of the 58 patients with lipogranuloma were associated with steatosis and/or steato-fibrosis. Of the 18 lipogranuloma patients with clinical information available for review, 15 (83%) had risk factors associated with fatty liver disease, such as alcohol use, obesity, hyperlipidemia, and diabetes mellitus. Although the incidence of these risk factors was greater in patients with lipogranuloma than in control group (60%), it did not reach statistical significance. CONCLUSION: Hepatic lipogranuloma is not limited to mineral oil use and commonly associated with hepatic steatosis, hepatitis C and fatty liver disease. With additional histological features of steato-fibrosis, lipogranuloma can also be used as a marker of prior hepatic steatosis.

关键词： Lipogranuloma Hepatitis C Fatty liver disease Steatosis Steato-fibrosis