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Hepatitis B virus outreach to immigrant population in Greater Boston Area: Key to improving hepatitis B knowledge

World Journal of Gastroenterology 2017年第42期23卷 7626-7634页

作者： Raissa Djoufack scarlett se yun cheon Aisha Mohamed Fatou Faye Korka Diouf Richard Colvin James Morrill Ann-Marie Duffy-Keane Ponni Perumalswami Gonzague Jourdain Dahlene Fusco Universite des Montagnes Wellesley College Cooper Medical School of Rowan University Suffolk University Division of General Internal Medicine MGH MGH Community Health Associates Icahn School of Medicine at Mount Sinai Institut de Recherche pour le Dé-veloppement Chiang Mai University Harvard T.H. Chan School of Public Health Division of Infectious Disease Department of Medicine Vaccine and Immunotherapy Center Laboratory of Systems Pharmacology Harvard Medical School

AIM To characterize the understanding of hepatitis B virus(HBV) and determine if outreach improves HBV understanding among Greater Boston Area immigrants. METHODS Six outreach sessions were held in various community venues in the Greater Boston Area. Verbal consent was obtained from participants prior to starting each session. Each session included a pre-session questionnaire, followed by a teaching session, and then a post-session questionnaire. In person interpreters were present for translation during the teaching session and assistance for questionnaire completion when needed. The questions were developed based on the HBV clinical experience of physicians who serve largely immigrant populations. Questionnaires included Likerttype scale, open-ended, and true-false questions. All results were anonymous. RESULTS One hundred and one people participated in this study. Participants were 30% male with ages ranging from 19 to 87 years. The study population included immigrants from 21 countries, as well as seven United States-born participants. The greatest numbers of participants were from Somalia(44%), Morocco(10%), and Cameroon(8%). Pre session questionnaires revealed that 42% of participants were unaware that HBV can cause cancer, and 50% were unaware that therapies for HBV exist. Our brief teaching intervention led to improved scores on post session questionnaires. For example, at baseline, 58% of participants responded correctly to the question "HBV infection can cause scarring of the liver and liver cancer", whereas 79% of participants responded correctly after the teaching session(P = 0.01). Furthermore, the mean of total correct answers in the true or false portion of the questionnaire increased from 5.5 to 7.6(P session targeting Boston Immigrants atrisk for HBV helped improve scores on HBV knowledge questionnaires. Outreach may empower at-risk patients to pro-actively seek HBV care.

关键词： Hepatitis B virus Outreach Linkage to care Immigrant Boston

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Bawu Decoction(八物汤) Ameliorates Benign Prostatic Hyperplasia in Rats

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Chinese Journal of Integrative Medicine 2017年第8期23卷 611-616页

作者： Ji-Hwan Eom se-yun cheon Kyung-Sook Chung Myung-Dong Kim Hyo-Jin An Department of Physiology College of Korean Medicine Sangji University Wonju-si Gangwon-do 220-702 Republic of Korea Department of Pharmacology College of Korean Medicine Sangji University Wonju-si Gangwon-do 220-702 Reoublic of Korea

Objective：To evaluate the efficacy of Bawu Decoction（八物汤,BWD,Palmul-tang in Korean）against benign prostatic hyperplasia（BPH）.Methods：Twenty-four male Wistar rats were divided into 4 groups,with 6 rats in each *** 4 study groups included sham-operated group（CON）,BPH model group,finasteride-treated group,and BWD-treated *** the groups except CON group received a subcutaneous injection of 10 mg/kg of testosterone,while CON group received *** at a dose of 5 mg/kg was administered to the finasteride-treated group for a period of 4 *** group received BWD at a dose of 200 mg/kg for 4 *** prostatic weight,prostate weight to body weight ratio,relative prostate weight ratio,serum testosterone and dihydrotestosterone（DHT）level,and histological analysis of prostatic tissue were ***：Compared to BPH model group,BWD administration was associated with reductions in prostatic weight,prostate and relative prostate weight ratio weight to body weight ratio（P〈0.05）.The concentration of serum testosterone and DHT were higher in BPH group compared with CON group（P〈0.05）.Administration of finasteride and BWD suppressed the elevation of serum testosterone and DHT levels significantly（both P〈0.05）.In addition,BWD suppressed the growth of prostatic tissue（P〈0.05）.Conclusion：BWD has suppressant effects on development of BPH through inhibition of serum testosterone and DHT.

关键词： benign prostatic hyperplasia Bawu Decotion Palmul-tang finasteride testosterone,dihydrotesterone rat

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