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Assessment of Sustainable Energy Strategy with Long-Term Global Energy Model Incorporating Nuclear Fuel Cycle

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Journal of Environmental Science and Engineering(B) 2012年第11期1卷 1215-1232页

作者： saurabh sharma Ryoichi Komiyama Yasumasa Fujii Department of Nuclear Engineering and Management Graduate School of Engineering The University of Tokyo Tokyo 113-8656Japan

This paper investigates long-term energy strategy compatible with significant reduction of world carbon dioxide （CO2） emissions, employing a long-term global energy model, Dynamic New Earth 21 （called DNE21）. The model seeks the optimal energy mix from 2000 to 2100 that minimizes the world total energy system cost under various kinds of energy and technological constraints, such as energy resource constraints, energy supply and demand balance constraints, and CO2 emissions constraints. This paper discusses the results of primary energy supply, power generation mix, CO2 emission, CCS （carbon capture and storage） and total system costs for six regions including world as a whole. To evaluate viable pathways forward for implementation of sustainable energy strategies, nuclear power generation is a viable source of clean and green energy to mitigate the CO2 emissions. Present research shows simulation results in two cases consisting of no CO2 regulation case （base case） and CO2 REG case （regulation case） which halves the world CO2 emissions by the year 2050. Main findings of this research describe that renewable and nuclear power generation will contribute significantly to mitigate the CO2 emission worldwide.

关键词： Energy model CCS (carbon capture and storage) renewable and nuclear power generation CO2 emissions.

The Utility of Fine-Needle Aspiration in the Diagnosis and Management of Follicular Thyroid Neoplasms:One Institution’s 10-Year Experience

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International Journal of Otolaryngology and Head & Neck Surgery 2012年第2期1卷 18-23页

作者： Robert Deeb Osama Alassi saurabh sharma Mei Lu Tamer Ghanem Department of Otolaryngology-Head and Neck Surgery Detroit USA Henry Ford Health System Detroit USA

Background: Classical teaching dictates that follicular adenoma (FA) can be distinguished from follicular carcinoma (FC) based on histologic features only. We retrospectively reviewed our institution’s 10-year experience in the use of fine-needle aspiration (FNA) to diagnose follicular thyroid neoplasms. Methods: Patients who had FNA of a thyroid neoplasm from 2000 to 2010 were reviewed. Diagnoses of FA, FC, or follicular neoplasm-not otherwise specified (NOS) were included. Cytopathological results were correlated with surgical pathology. Results: Of 138 patients, 65% underwent surgery. FNA diagnosis for FA had a sensitivity of 50% and specificity of 71%. 25% of patients with an FNA diagnosis of FA were found to have cancer after surgical specimen examination. FNA diagnosis for FC had a sensitivity of 60% and specificity of 94%. Conclusions: FNA has a low sensitivity for diagnosing FA. Surgical pathology remains the gold standard for differentiating follicular carcinoma from adenoma.

关键词： Fine Needle Aspiration Follicular Thyroid Adenoma Carcinoma

Recent advances in biopolymer-based hemostatic materials

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Regenerative Biomaterials 2022年第1期9卷 1080-1105页

作者： Marvin Mecwan Jinghang Li Natashya Falcone Menekse Ermis Emily Torres Ramon Morales Alireza Hassani Reihaneh Haghniaz Kalpana Mandal saurabh sharma Surjendu Maity Fatemeh Zehtabi Behnam Zamanian Rondinelli Herculano Mohsen Akbari Johnson V.John Ali Khademhosseini Terasaki Institute for Biomedical Innovation Los AngelesCA 90064USA Department of Molecular and Cell Biology University of CaliforniaBerkeleyCA 94720USA Department of Biomedical Engineering University of Southern CaliforniaLos AngelesCA 90089USA Bioengineering&Biomaterials Group School of Pharmaceutical SciencesSao Paulo State University(UNESP)AraraquaraSP 14800-903Brazil Department of Mechanical Engineering University of VictoriaVictoriaBC V8P 5C2Canada Biotechnology Center Silesian University of TechnologyGliwice 44-100Poland

Hemorrhage is the leading cause of trauma-related deaths,in hospital and prehospital *** is a complex mechanism that involves a cascade of clotting factors and proteins that result in the formation of a strong *** certain surgical and emergency situations,hemostatic agents are needed to achieve faster blood coagulation to prevent the patient from experiencing a severe hemorrhagic ***,it is critical to consider appropriate materials and designs for hemostatic *** materials have been fabricated as hemostatic agents,including synthetic and naturally derived *** to synthetic polymers,natural polymers or biopolymers,which include polysaccharides and polypeptides,have greater biocompatibility,biodegradability and ***,in this review,we focus on biopolymer-based hemostatic agents of different forms,such as powder,particles,sponges and ***,we discuss biopolymer-based hemostatic materials currently in clinical trials and offer insight into next-generation hemostats for clinical translation.

关键词： hemostasis coagulation polysaccharides polypeptides biomaterials

The Utility of Fine-Needle Aspiration in the Diagnosis and Management of Follicular Thyroid Neoplasms:One Institution’s 10-Year Experience

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Impact of frailty on endoscopic retrograde cholangiopancreatography outcomes in nonagenarians:A United States national experience

International Journal of Otolaryngology and Head & Neck Surgery 2012年第2期

作者： Robert Deeb Osama Alassi saurabh sharma Mei Lu Tamer Ghanem

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World Journal of Gastrointestinal Endoscopy 2024年第3期16卷 148-156页

作者： Sanket Dhirubhai Basida Dushyant Singh Dahiya Muhammad Nadeem Yousaf Brinda Basida Bhanu Siva Mohan Pinnam Manesh Kumar Gangwani Hassam Ali Sahib Singh Yash R Shah Daksh Ahluwalia Mihir Prakash Shah saurabh Chandan Neil R sharma Shyam Thakkar Department of Internal Medicine University of Missouri-ColumbiaColumbiaMO 65212United States Division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States Division of Gastroenterology and Hepatology University of MissouriColumbiaMO 65212United States Department of Rheumatology Medical College of GeorgiaAugusta UniversityNorth AugustaGA 30912United States Department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States Department of Internal Medicine The University of ToledoToledoOH 43606United States Division of Gastroenterology and Hepatology East Carolina University/Brody School of MedicineGreenvilleNC 27858United States Department of Internal Medicine Sinai HospitalBaltimoreMD 21215United States Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Division of Gastroenterology and Hepatology Creighton University School of MedicineOmahaNE 68131United States Division of Interventional Oncology&Surgical Endoscopy GI Oncology Tumor Site TeamParkview Cancer InstituteParkview HealthFort WayneIN 46845United States Section of Gastroenterology&Hepatology West Virginia University School of MedicineMorgantownWV 26505United States

BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an essential therapeutic tool for biliary and pancreatic *** and elderly patients,especially those aged≥90 years are generally considered a higher-risk population for ERCP-related *** To investigate outcomes of ERCP in the Non-agenarian population(≥90 years)concerning *** This is a cohort study using the 2018-2020 National Readmission *** aged≥90 were identified who underwent ERCP,using the international classification of diseases-10 code with clinical *** Hopkins’s adjusted clinical groups frailty indicator was used to classify patients as frail and *** primary outcome was mortality,and the secondary outcomes were morbidity and the 30 d readmission rate related to *** used univariate and multivariate regression models for *** A total of 9448 patients were admitted for any indications of *** and non-frail patients were 3445(36.46%)and 6003(63.53%)*** for ERCP were Choledocholithiasis(74.84%),Biliary pancreatitis(9.19%),Pancreatico-biliary cancer(7.6%),Biliary stricture(4.84%),and Cholangitis(1.51%).Mortality rates were higher in frail group[adjusted odds ratio(aOR)=1.68,P=0.02].The Intra-procedural complications were insigni-ficant between the two groups which included bleeding(aOR=0.72,P=0.67),accidental punctures/lacerations(aOR=0.77,P=0.5),and mechanical ventilation rates(aOR=1.19,P=0.6).Post-ERCP complication rate was similar for bleeding(aOR=0.72,P=0.41)and post-ERCP pancreatitis(aOR=1.4,P=0.44).Frail patients had a longer length of stay(6.7 d vs 5.5 d)and higher mean total charges of hospitalization($78807 vs$71392)compared to controls(P<0.001).The 30 d all-cause readmission rates between frail and non-frail patients were similar(P=0.96).CONCLUSION There was a significantly higher mortality risk and healthcare burden amongst nonagenarian frail patients undergoing ERCP compared

关键词： Endoscopic retrograde cholangiopancreatography Nonagenarians Frailty Mortality Healthcare burden

Sustainable remediation of failed slope using helical soil nails

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Journal of Mountain Science 2023年第6期20卷 1742-1758页

作者： saurabh RAWAT Ashok Kumar GUPTA Pankaj sharma Department of Civil Engineering Jaypee University of Information Technology Department of Civil Engineering Chitkara University Institute of Engineering and TechnologyChitkara University

The performance of a helical soil nailed structure is dependent on the installation torque required and the consequent pullout resistance *** present research work aims at proposing theoretical models to estimate the required torque during installation of helical soil ***,theoretical models are also developed to predict the pullout capacity of single and group of the helical nail for uniform and staggered *** proposed model predicts the pure-elastic and elastic-plastic pullout behavior of different helical *** equation for estimating the capacity-totorque Ratio(Kt)has also been developed for different nail shaft *** results from the proposed models are validated with experimental results obtained from model testing of both single and group of helical *** predicted results are also compared for validation with the published *** results for installation torque and pullout load depict that the developed models predict values which are in accordance with the experimental results and are also found in good agreement with the published ***,the proposed models can effectively be used by the filed engineers for estimating the required installation torque and corresponding pullout capacities for single or double plate helical soil nails in cohesionless soil under surcharge pressure range of 0–50k Pa.

关键词： Theoretical torque Pullout force Pure elastic Elastic plastic Capacity to torque ratio

Probiotic fermentation of polyphenols: potential sources of novel functional foods

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Food Production, Processing and Nutrition 2022年第1期4卷 259-274页

作者： Rohit sharma Bhawna Diwan Brij Pal Singh saurabh Kulshrestha Faculty of Applied Sciences&Biotechnology Shoolini University of Biotechnology and Management SciencesSolan173229India Department of Microbiology Central University of HaryanaMahendragarhIndia

Fermented functional food products are among the major segments of food processing *** imparts several characteristic effects on foods including the enhancement of organoleptic characteristics,increased shelf-life,and production of novel health beneficial ***,in addition to macronutrients present in the food,secondary metabolites such as polyphenols are also emerging as suitable fermentable *** the traditional antimicrobial view of polyphenols,accumulating research shows that polyphenols exert differential effects on bacterial communities by suppressing the growth of pathogenic microbes while concomitantly promoting the proliferation and survival of probiotic ***,probiotic bacteria not only survive among polyphenols but also induce their fermentation which often leads to improved bioavailability of polyphenols,production of novel metabolic intermediates,increased polyphenolic content,and thus enhanced functional capacity of the fermented *** addition,selective fermentation of combinations of polyphenol-rich foods or fortification with polyphenols can result in novel functional *** present narrative review specifically explores the potential of polyphenols as fermentable substrates in functional *** discuss the emerging bidirectional relationship between polyphenols and probiotic bacteria with an aim at promoting the development of novel functional foods based on the amalgamation of probiotic bacteria and polyphenols.

关键词： Probiotics Polyphenols Fermented Foods Lactic acid bacteria Tea

QSPCA: A two-stage efficient power control approach in D2D communication for 5G networks

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Intelligent and Converged Networks 2021年第4期2卷 295-305页

作者： saurabh Chandra Prateek Rohit sharma Rajeev Arya Korhan Cengiz Department of Electronics and Communication Engineering National Institute of Technology PatnaAshok RajpathPatna 800005India Department of Electrical-Electronics Engineering Trakya UniversityEdirne 22030Turkey

The existing literature on device-to-device(D2D)architecture suffers from a dearth of analysis under imperfect channel *** is a need for rigorous analyses on the policy improvement and evaluation of network ***,a two-stage transmit power control approach(named QSPCA)is proposed:First,a reinforcement Q-learning based power control technique and;second,a supervised learning based support vector machine(SVM)*** model replaces the unified communication model of the conventional D2D setup with a distributed one,thereby requiring lower resources,such as D2D throughput,transmit power,and signal-to-interference-plus-noise ratio as compared to existing *** confirm that the QSPCA technique is better than existing models by at least 15.31%and 19.5%in terms of throughput as compared to SVM and Q-learning techniques,*** customizability of the QSPCA technique opens up multiple avenues and industrial communication technologies in 5G networks,such as factory automation.

关键词： device-to-device(D2D) interference Internet of Things(IoT) machine learning power control Q-learning support vector machine(SVM) 5G

Translational products of adipose tissue-derived mesenchymal stem cells:Bench to bedside applications

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World Journal of Stem Cells 2021年第10期13卷 1360-1381页

作者： Shilpa sharma Sathish Muthu Madhan Jeyaraman Rajni Ranjan saurabh Kumar Jha Department of Pediatric Surgery All India Institute of Medical SciencesNew Delhi 110029India Indian Stem Cell Study Group LucknowUttar Pradesh 226010India Department of Orthopaedics Government Medical College and HospitalDindigulTamil Nadu 624304India Research Scholar Department of BiotechnologySchool of Engineering and TechnologyGreater NoidaSharda UniversityUttar Pradesh 201306India Department of Orthopaedics School of Medical Sciences and ResearchSharda UniversityGreater NoidaUttar Pradesh 201306India Department of Biotechnology School of Engineering and TechnologySharda UniversityGreater NoidaUttar Pradesh 201306India

With developments in the field of tissue engineering and regenerative medicine,the use of biological products for the treatment of various disorders has come into the limelight among researchers and *** all the available biological tissues,research and exploration of adipose tissue have become more *** tissue engineering aims to develop by-products and their substitutes for their regenerative and immunomodulatory *** use of biodegradable scaffolds along with adipose tissue products has a major role in cellular growth,proliferation,and *** tissue,apart from being the powerhouse of energy storage,also functions as the largest endocrine organ,with the release of various *** progenitor cells among the heterogeneous population in the adipose tissue are of paramount importance as they determine the capacity of regeneration of these *** results of adipose-derived stemcell assisted fat grafting to provide numerous growth factors and adipokines that improve vasculogenesis,fat graft integration,and survival within the recipient tissue and promote the regeneration of tissue are *** tissue gives rise to various by-products upon *** article highlights the significance and the usage of various adipose tissue by-products,their individual characteristics,and their clinical applications.

关键词： Adipose tissue Stem cells Fat graft Clinical applications Mesenchymal stem cells