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Health 2015年第14期7卷 1841-1846页

作者： Takashi Naruse Rumiko Tsuchiya Natsuki Yamamoto satoko Nagata Department of Community Health Nursing Graduate School of Medicine University of Tokyo Tokyo Japan

To prevent the development of metabolic syndrome among adult members of the community, improving the participation rate in the specific medical checkup (a medical examination focused on factors associated with metabolic syndrome prior to the onset of lifestyle-related disease) is an important public health issue. This study used claim data and health checkup data and aimed to detect those community-dwelling adults who were least likely to participate in the specific medical checkup. Analysis included the medical and health checkup chart data of 61,753 adults aged 60 - 69 years (as of April 2011) who lived in Fukui prefecture, Japan. The chi-squared interaction was used to analyze data. If a person did not participate in the specific medical checkup, individual was categorized as “absent.” Between April 2012 and March 2013, 66.3% of subjects were absent from the specific medical checkup. Those most likely to be absent included those who were also absent at the previous year’s checkup, those who were men, and those who did not have an examination for hypertension;87.9% of patients who met all of these criteria were absent. Among women who were absent at the previous year’s checkup, the absentee rate differed by about 10.0% between those whose municipalities did (74.8%) or did not (84.2%) have a free checkup program. Our findings may help public health professionals detect those who require intervention and to effectively and efficiently improve participation in the specific medical checkup.

关键词： Health Checkup Adults Metabolic Syndrome

新西兰抗高血压药物费用(1981-1987)

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国外医学（卫生经济分册） 1990年第1期7卷 26-29页

作者： kawachi I 高大林

1981-1987年间新西兰抗高血压药物的通货膨胀调节支出增加了61.7%,即按1961年定值新西兰元计算,从2140新西兰元上升到3460元新西兰元.费用支出增加的大部分(56.3%)是由药物的实际成本提高造成的,而同期药物治疗的病人数变化不大.1981-1... 详细信息

1981-1987年间新西兰抗高血压药物的通货膨胀调节支出增加了61.7%,即按1961年定值新西兰元计算,从2140新西兰元上升到3460元新西兰元.费用支出增加的大部分(56.3%)是由药物的实际成本提高造成的,而同期药物治疗的病人数变化不大.1981-1987年高血压处方的平均费用增加了46.1%,即按1981年定值新西兰元计算,从7.30新西兰元上升到10.66新西兰元,然而同期抗高血压药物的平均通货膨胀调节价格下降了10.8%。处方的平均费用增加主要原因是处方形式发生变化以及新药进入市场。如果增长的开支不能被证明对治疗结果有明显的改善,那么开支继续增长将会对抗高血压治疗的成本效果带来深远的影响.

关键词：高血压新西兰药物费用

Appendiceal Orifice Inflammation Mimicking Submucosal Tumor on Roentgenogram in Ulcerative Colitis

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Health 2014年第10期6卷 926-928页

作者： Mitsuro Chiba Tsuyotoshi Tsuji satoko Tsuda Masafumi Komatsu Division of Gastroenterology Akita City Hospital Akita Japan

Appendiceal orifice inflammation (AOI) is observed as skip lesion in distal ulcerative colitis (UC). The endoscopic frequency of AOI is reported to be 7.9% to 76% of distal colitis. UC is a relapsing and remitting disease and a morphological change of the large bowel occurs over time. Patient and physician can easily understand the shape of the whole large bowel not through endoscopic photograph but by roentgenogram of the bowel. Therefore, the authors undertake barium enema study when a diagnosis of UC is made. We have experienced a patient with proctitis in which an appendiceal submucosal tumor (SMT) was suspected on the roentgenogram but it was turned out to be a protruding lesion of AOI. A 16-year-old boy visited us with complaining of blood in his stool for the past 10 days. Sigmoidoscopy revealed mild diffuse inflammation. Crypt abscess was found in biopsy specimen. A diagnosis of UC, proctitis type, was made. A double contrast barium enema study revealed a defect shadow with a smooth surface, length 37 mm, height 12 mm, over the appendix. An appendiceal SMT was suspected. Abdominal ultrasonography and computed tomography were non-contributory. Colonoscopy revealed a spiral inflamed mucosa at the site of an appendiceal orifice. There was an inflammation in the cecum surrounding the orifice. Biopsy specimen of the appendiceal orifice showed inflammatory cells infiltration, goblet cell depletion, and cryptitis. The suspected SMT lesion was concluded to be AOI.

关键词： Appendix Ulcerative Colitis Submucosal Tumor

Evaluation of magnifying colonoscopy in the diagnosis of serrated polyps

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World Journal of Gastroenterology 2012年第32期18卷 4308-4316页

作者： Shinya Ishigooka Masahito Nomoto Nobuyuki Obinata Yoshichika Oishi Yoshinori Sato satoko Nakatsu Midori Suzuki Yoshiko Ikeda Tadateru Maehata Tomoaki Kimura Yoshiyuki Watanabe Takashi Nakajima Hiro-o Yamano Hiroshi Yasuda Fumio Itoh Department of Internal Medicine Division of Gastroenterology and HepatologySt.Marianna University School of MedicineKawasaki 216-8511Japan Center of Gastroenterology St.Marianna Toyoko HospitalKawasaki 211-0063Japan Department of Gastroenterology Akita Red Cross HospitalAkita 010-1495Japan

AIM:To elucidate the colonoscopic features of serrated lesions of the colorectum using magnifying ***:Broad division of serrated lesions of the colorectum into hyperplastic polyps(HPs),traditional serrated adenomas(TSAs),and sessile serrated adenomas/polyps(SSA/Ps) has been proposed on the basis of recent molecular biological ***,few reports have examined the colonoscopic features of these divisions,including magnified colonoscopic *** study examined 118 lesions excised in our hospital as suspected serrated lesions after magnified observation between January 2008 and September *** characteristics(sex,age),conventional colonoscopic findings(location,size,morphology,color,mucin) and magnified colonoscopic findings(pit pattern diagnosis) were interpreted by five colonoscopists with experience in over 1000 colonoscopies,and were compared with histopathological *** pit patterns were categorized according to Kudo's classification,but a more detailed investigation was also performed using the subclassification [type Ⅱ-Open(type Ⅱ-O),type Ⅱ-Long(type Ⅱ-L),or type Ⅳ-Serrated(type Ⅳ-S)] proposed by Kimura T and Yamano ***:Lesions comprised 23 HPs(23/118:19.5%),39 TSAs(39/118:33.1%:with cancer in one case),50 SSA/Ps(50/118:42.4%:complicated with cancer in three cases),and six others(6/118:5.1%).We excluded six others,including three regular adenomas,one hamartoma,one inflammatory polyp,and one juvenile polyp for further *** colonoscopy showed that SSA/Ps were characterized as larger in diameter than TSAs and HPs(SSA/P vs HP,13.62 ± 8.62 mm vs 7.74 ± 3.24 mm,P < 0.001;SSA/Ps vs TSA,13.62 ± 8.62 mm vs 9.89 ± 5.73 mm,P < 0.01);common in the right side of the colon [HPs,30.4%(7/23):TSAs,20.5%(8/39):SSA/P,84.0%(42/50),P < 0.001];flat-elevated lesion [HPs,30.4%(7/23):TSAs,5.1%(2/39):SSA/Ps,90.0%(45/50),P < 0.001];normal-colored or pale imucosa [HPs,34.8%(8/23):TSAs,10.3%(4/39):SSA/Ps,80%(40/50),P < 0.00

关键词：病理组织学诊断检查结果结肠镜放大镜锯齿肉病理特征评价

Therapeutic target for nephrotic syndrome: Identification of novel slit diaphragm associated molecules

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World Journal of Nephrology 2014年第3期3卷 77-84页

作者： Yoshiyasu Fukusumi Naoko Miyauchi Taeko Hashimoto Akira Saito Hiroshi kawachi Department of Cell Biology Institute of Nephrology Niigata University Graduate School of Medical and Dental Sciences Niigata 951-8510 Japan

The slit diaphragm bridging the neighboring foot processes functions as a final barrier of glomerular capillary wall for preventing the leak of plasma proteins into primary *** is now accepted that the dysfunction of the sit diaphragm contributes to the development of proteinuria in several glomerular ***,a gene product of NPHS1,a gene for a congenital nephrotic syndrome of Finnish type,constitutes an extracellular domain of the slit *** was identified as a gene product of NPHS2,a gene for a familial steroid-resistant nephrotic syndrome of *** binds the cytoplasmic domain of *** then,CD2 associated protein,NEPH1 and transient receptor potential-6 were also found as crucial molecules of the slit *** order to explore other novel molecules contributing to the development of proteinuria,we performed a subtraction hybridization assay with a normal rat glomerular RNA and a glomerular RNA of rats with a puromycin aminonucleoside nephropathy,a mimic of a human minimal change type nephrotic *** we have found that synaptic vesicle protein 2B,ephrin-B1 and neurexin were already downregulated at the early stage of puromycin amino-nucleoside nephropathy,and that these molecules were localized close to *** is conceivable that these molecules are the slit diaphragm associated molecules,which participate in the regulation of the barrier *** molecules could be targets to establish a novel therapy for nephrotic syndrome.

关键词：毛细血管壁肾小球治疗方法临床分析

Intergrating Law and Social Epidemiology

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Intergrating Law and Social Epidemiology

Use of Analogy by Public Health Nurses in Problem Solving for Individual Consultations in Japan: A Multiple Case Study

北京论坛（2005）文明的和谐与共同繁荣——全球化视野...

作者： Scott Burris Ichiro kawachi Austin Sarat Temple University

Social epidemiology has made a powerful case that health is determined not just by individual-level factors such as our genetic make-up,access to medical services,or lifestyle choices,but also by social conditions,including the economy,law,and ***,at the level of populations, evidence suggests that these"structural"factors are the predominant influences on *** acholars in public

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Open Journal of Nursing 2017年第3期7卷 345-360页

作者： Masako Kageyama Taeko Shimazu Atsuko Taguchi satoko Nagata Kathy Magilvy Area of Integrated Health and Nursing Science Osaka University Graduate School of Medicine Suita Japan National College of Nursing Kiyose Japan Department of Public Health Nursing Division of Health Sciences Tohoku University Graduate School of Medicine Sendai Japan Department of Community Health Nursing Graduate School of Medicine The University of Tokyo Tokyo Japan University of Colorado College of Nursing Denver USA

Aim: Nurses must develop good problem-solving skills (PSS) to work in the complex health care environment. This study explored PHNs’ use of analogy in PSS development. The purposes of the study were to clarify how PSS developed in one area (i.e., mental health) could be applied to another area (i.e., maternal health) and whether new PSS could develop in response to PSS gained in another area. Methods: A multiple case study was conducted using interviews. We interviewed 27 consultations from eight Japanese PHNs who consulted in mental health departments before transferring to maternal health departments. The data on how PHNs applied PSS in the selection, mapping, evaluation, and learning stages of the analogy process were extracted from transcribed interviewed data and compared. Results: PHNs provided 59 PSS used in 27 consultations. All PHNs applied past mental health PSS to solve new problems in maternal health. They tended to select past PSS based on structural similarity and to apply PSS via low-level abstraction in serious situations or preventively to avoid causing the current situation to worsen. Notably, PHNs developed maternal health PSS by using past mental health PSS;these new PSS were derived through analogy from various failures and successes. Conclusions: PSS developed in one area can be applied in another area, and new PSS can develop through applying these previous PSS. Identification of structural similarities and preventive analogies must be included in nursing education, especially for nurses working in public health fields.

关键词： Analogy Consultation Nursing Education Problem Solving Public Health Nurse

Sigmoid colon endometriosis treated with laparoscopy-assisted sigmoidectomy:Significance of preoperative diagnosis

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World Journal of Gastroenterology 2007年第40期13卷 5400-5402页

作者： Motohira Yoshida Yuji Watanabe Atsushi Horiuchi Yuji Yamamoto Hiroki Sugishita Kanji kawachi Department of Organ Regenerative Surgery Ehime University Graduate School of MedicineShitsukawaToonEhime 791-0295Japan

我们在场外科手术前地正确地被诊断并且经历了最低限度地侵略的外科的有 S 字形的结肠子宫内膜增生的一个女病人。她与直肠的流血和便秘进入我们的医院。我们执行了几工作 ups。显示出的 S 字形的冒号狭窄由粘膜下层肿瘤引起了的结肠镜... 详细信息

我们在场外科手术前地正确地被诊断并且经历了最低限度地侵略的外科的有 S 字形的结肠子宫内膜增生的一个女病人。她与直肠的流血和便秘进入我们的医院。我们执行了几工作 ups。显示出的 S 字形的冒号狭窄由粘膜下层肿瘤引起了的结肠镜检查和内视镜的 ultrasonography，和磁性的回声成像揭示了在 T1 加权、 T2 加权的成像上显示信号 hy-pointensity 的一个 S 字形的冒号肿瘤。然而， colonoscopic 帮助 ultrasonography 的针针吸活组织检查不能指定肿瘤特征。从这些考试，当 S 字形的冒号子宫内膜增生和帮助 laparoscopy 的乙状结肠切除术被执行，损害被诊断。从 resected 标本的病理学的诊断与外科手术前的诊断相同，即，结肠的子宫内膜增生。因为肠的子宫内膜增生的鉴别诊断似乎困难，小心的外科手术前的诊断被要求包括最低限度地侵略的外科选择治疗。

关键词：子宫内膜异位手术诊断腹腔镜治疗

Nutritional status in relation to lifestyle in patients with compensated viral cirrhosis

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World Journal of Gastroenterology 2012年第40期18卷 5759-5770页

作者： Fumikazu Hayashi Chika Momoki Miho Yuikawa Yuko Simotani Etsushi Kawamura Atsushi Hagihara Hideki Fujii Sawako Kobayashi Shuji Iwai Hiroyasu Morikawa Masaru Enomoto Akihiro Tamori Norifumi Kawada satoko Ohfuji Wakaba Fukusima Daiki Habu Department of Medical Nutrition Graduate School of Life ScienceOsaka City University Department of Hepatology Graduate School of MedicineOsaka City University Department of Hepatology Graduate School of MedicineOsaka City UniversityOsaka 545-8585Japan Department of Public Health Graduate School of MedicineOsaka City University

AIM:To assess the nourishment status and lifestyle of non-hospitalized patients with compensated cirrhosis by using noninvasive ***:The subjects for this study consisted of 27 healthy volunteers,59 patients with chronic viral hepatitis,and 74 patients with viral cirrhosis,from urban *** assessed the biochemical blood tests,anthropometric parameters,diet,lifestyle and physical activity of the patients.A homeostasis model assessment-insulin resistance(HOMA-IR) value of ≥ 2.5 was considered to indicate insulin *** measured height,weight,waist circumference,arm circumference,triceps skin-fold thickness,and handgrip strength,and calculated body mass index,arm muscle circumference(AMC),and arm muscle area(AMA).We interviewed the subjects about their dietary habits and lifestyle using health assessment computer *** surveyed daily physical activity using a *** and multivariate logistic regression modeling were used to identify the relevant factors for insulin ***:The rate of patients with HOMA-IR ≥ 2.5(which was considered to indicate insulin resistance) was 14(35.9%) in the chronic hepatitis and 17(37.8%) in the cirrhotic ***(%)(control vs chronic hepatitis,111.9% ± 10.5% vs 104.9% ± 10.7%,P = 0.021;control vs cirrhosis,111.9% ± 10.5% vs 102.7% ± 10.8%,P = 0.001) and AMA(%)(control vs chronic hepatitis,128.2% ± 25.1% vs 112.2% ± 22.9%,P = 0.013;control vs cirrhosis,128.2% ± 25.1% vs 107.5% ± 22.5%,P = 0.001) in patients with chronic hepatitis and liver cirrhosis were significantly lower than in the control *** strength(%) in the cirrhosis group was significantly lower than in the controls(control vs cirrhosis,92.1% ± 16.2% vs 66.9% ± 17.6%,P < 0.001).The results might reflect a decrease in muscle *** total nutrition intake and amounts of carbohydrates,protein and fat were not significantly different amongst the *** activity levels(kcal/d)(control vs cirrhosis,210 ± 11

关键词：生活方式营养状况肝硬化病毒性 logistic回归模型患者胰岛素抵抗慢性肝炎

Successful coil embolization with a basic technique for ruptured posterior tibial artery in a patient with Ehlers-Danlos syndrome type IV: A case report

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Case Reports in Clinical Medicine 2013年第2期2卷 131-134页

作者： satoko Nezu Morio Nagahata Keisuke Onishi Rei Kondo Shinjiro Saito Department of Diagnostic and Interventional Neuroradiology Yamagata City Hospital Saiseikan Yamagata Japan Department of Neurosurgery Yamagata City Hospital Saiseikan Yamagata Japan Department of Surgery Yamagata City Hospital Saiseikan Yamagata Japan

The surgical management of vascular complication with Ehlers-Danlos Syndrome type IV (EDS-IV) is extremely challenging because of its tissue or organ fragility including arteries. Less traumatic maneuvers and devices have been recommended to perform the endovascular treatment for the vascular lesion of EDS-IV, although the endovascular procedure is less invasive than surgical intervention. We report a 23-year-old man with EDS-IV suffered from left posterior tibial arterial rupture. We performed internal trapping of the ruptured segment using detachable coils with a standard technique via the contralateral femoral artery puncture. The patient was discharged without any complication associated with the endovascular procedure. Embolization by a basic technique, performed with greatest care, is a safe and useful treatment option which we radiologists should try for managing EDS-IV patients.

关键词： Ehlers-Danlos Syndrome Type IV Peripheral Arterial Rupture Coil Embolization