检索结果-南通市图书馆

C-terminal frameshift mutations generate viable knockout mutants with developmental defects for three essential protein kinases

在线全文

学校读者我要写书评

暂无评论

aBIOTECH 2024年第2期5卷 219-224页

作者： Yun Zhang miao-miao Cui Run-Nan Ke Yue-Dan Chen Kabin Xie National Key Laboratory of Crop Genetic Improvement Hubei Hongshan LaboratoryHuazhong Agricultural UniversityWuhan 430070China Hubei Key Laboratory of Plant Pathology Huazhong Agricultural UniversityWuhan 430070China

Loss-of-function mutants are fundamental resources for gene function ***,it is difficult to generate viable and heritable knockout mutants for essential ***,we show that targeted editing of the C-terminal sequence of the embryo lethal gene MITOGEN-ACTIVATED PROTEIN KINASES 1(OsMPK1)results in weak *** C-terminal-edited osmpk1 mutants displayed severe developmental defects and altered disease resistance but generated tens of viable seeds that inherited the *** the same C-terminal editing approach,we also obtained viable mutants for a wallassociated protein kinase(Os07g0493200)and a leucine-rich repeat receptor-like protein kinase(Os01g0239700),while the null mutations of these genes were *** data suggest that protein kinase activity could be reduced by introducing frameshift mutations adjacent to the C-terminus,which could generate valuable resources for gene function studies and tune protein kinase activity for signaling pathway engineering.

关键词： CRISPR/Cas9 Lethal mutant Protein kinases Genome editing C-terminus

Enhancing sheepgrass through genomic exploration and targeted editing

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第3期67卷 629-630页

作者： miao Sun Sanwen Huang Yao Zhou Key Laboratory of Plant Molecular Physiology Institute of BotanyChinese Academy of SciencesBeijing 100093China State Key Laboratory of Tropical Crop Breeding Shenzhen BranchGuangdong Laboratory of Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China State Key Laboratory of Tropical Crop Breeding Chinese Academy of Tropical Agricultural SciencesHaikou 571101China

The growth of grass industry is essential for meeting human needs for proteins and sustaining grassland ecosystems(Bengtsson et al., 2019). Leymus chinensis, also known as sheepgrass, is a perennial Triticeae forage r... 详细信息

关键词： grassland sheep ecosystems

An adaptive large neighborhood search for the multi-point dynamic aggregation problem

在线全文

学校读者我要写书评

暂无评论

Control Theory and Technology 2024年第3期22卷 360-378页

作者： Shengyu Lu Bin Xin Jie Chen miao Guo School of Automation Beijing Institute of TechnologyBeijing 100081China National Key Lab of Autonomous Intelligent Unmanned Systems Beijing 100081China Department of Control Science and Engineering Tongji UniversityShanghai 201804China

The multi-point dynamic aggregation(MPDA)problem is a challenging real-world *** the MPDA problem,the demands of tasks keep changing with their inherent incremental rates,while a heterogeneous robot fleet is required to travel between these tasks to change the time-varying state of each *** robots are allowed to collaborate on the same task or work separately until all tasks are *** is challenging to generate an effective task execution plan due to the tight coupling between robots abilities and tasks'incremental rates,and the complexity of robot *** effectiveness consideration,we use the variable length encoding to avoid redundancy in the solution *** creatively use the adaptive large neighborhood search(ALNS)framework to solve the MPDA *** the proposed algorithm,high-quality initial solutions are generated through multiple problem-specific solution construction *** heuristics are also used to fix the broken solution in the novel integrated decoding-construction repair process of the ALNS *** results of statistical analysis by the Wilcoxon rank-sum test demonstrate that the proposed ALNS can obtain better task execution plans than some state-of-the-art algorithms in most MPDA instances.

关键词： Adaptive large neighborhood search(ALNS) Multi-point dynamic aggregation(MPDA) Heuristic solution construction Multi-robot collaboration

Adaptive Bistable Stochastic Resonance Based Weak Signal Reception in Additive Laplacian Noise

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Communications 2024年第1期21卷 228-241页

作者： Jin Liu Zan Li Qiguang miao Li Yang School of Computer Science and Technology Xidian UniversityXi’an 710071China State Key Laboratory of Integrated Services Networks Xidian UniversityXi’an 710071China

Weak signal reception is a very important and challenging problem for communication systems especially in the presence of non-Gaussian noise,and in which case the performance of optimal linear correlated receiver degrades *** at this,a novel uncorrelated reception scheme based on adaptive bistable stochastic resonance(ABSR)for a weak signal in additive Laplacian noise is *** analyzing the key issue that the quantitative cooperative resonance matching relationship between the characteristics of the noisy signal and the nonlinear bistable system,an analytical expression of the bistable system parameters is *** this basis,by means of bistable system parameters self-adaptive adjustment,the counterintuitive stochastic resonance(SR)phenomenon can be easily generated at which the random noise is changed into a benefit to assist signal ***,it is demonstrated that approximately 8dB bit error ratio(BER)performance improvement for the ABSR-based uncorrelated receiver when compared with the traditional uncorrelated receiver at low signal to noise ratio(SNR)conditions varying from-30dB to-5dB.

关键词： adaptive bistable stochastic resonance additive Laplacian noise low signal to noise ratio uncorrelated reception scheme weak signal reception

Mechanical behavior of nanorubber reinforced epoxy over a wide strain rate loading

在线全文

学校读者我要写书评

暂无评论

Nano Materials Science 2024年第1期6卷 106-114页

作者： Yinggang miao Jianping Yin Wenxuan Du Lianyang Chen Joint International Research Laboratory of Impact Dynamics and Its Engineering Applications School of AeronauticsNorthwestern Polytechnical UniversityXi'anShaanxi710072China State Key Laboratory for Strength and Vibration of Mechanical Structures Xi'an Jiaotong UniversityXi'anShaanxi710049China Shaanxi Key Laboratory of Impact Dynamics and Its Engineering Application School of AeronauticsNorthwestern Polytechnical UniversityXi'anShaanxi710072China

Nanorubber/epoxy composites containing 0,2,6 and 10 wt%nanorubber are subjected to uniaxial compression over a wide range of strain rate from 8×10^(-4) s^(-1) to~2×10^(4) s^(-1).Unexpectedly,their strain rate sensitivity and strain hardening index increase with increasing nanorubber *** mechanisms are proposed based on numerical simulations using a unit cell *** increase in the strain rate sensitivity with increasing nanorubber content results from the fact that the nanorubber becomes less incompressible at high strain,generating a higher hydro-static *** shear localization starts to occur in the epoxy under a strain rate of 22,000 s^(-1) when the strain exceeds *** presence of nanorubber in the epoxy reduces adiabatic shear localization by preventing it from propagating.

关键词： Strain rate Strain hardening Nano rubber Epoxy Adiabatic shearing localization

Photocatalytic transformation of selected biomass derivatives to value added chemicals and hydrogen fuel

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第3期35卷 19-26页

作者： Xiangjun Liu Shuai Zhang miao Wang Junqi Wang School of Human Settlements and Civil Engineering Xi'an Jiaotong UniversityXi'an 710049China

Biomass is the most bountiful renewable carbon resource on *** transformation is a promising method to utilize biomass to obtain high-value-added chemicals and it has more obvious advantages compared with thermochemical and biological processes due to the milder operational conditions,fewer reagents and *** material is one of the most common kinds of heterogeneous biomass photocatalysts,which has the advantages of high selectivity,stable catalytic performance,long activation time,and low *** this paper,the significant research progress on the photocatalytic transformation of biomass with semiconductor materials to produce high-value-added chemicals is reviewed,and the three most typical semiconductor photocatalysts(TiO_(2),Cd S,and g-C_(3)N_(4))are *** photocatalytic mechanism and photocatalytic system optimization including structural modification,metal co-catalyst loading,and introduction of heterojunction are ***,the main problems,the development direction and trend of semiconductor materials in photocatalytic transformations of biomass in the future are prospected,which provide guidance and inspiration for the further development of semiconductor photocatalysts and make contributions to the progress in efficient utilization of biomass.

关键词： Photocatalytic transformation Biomass Semiconductor material H_(2) High value-added chemical

Heat Transfer Characteristics of a Microchannel Heat Sink with Highly-Dense Micro-Jet Arrays

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第3期33卷 1148-1160页

作者： ZHANG Yu CHEN Xiaoyan miao Lin CHEN Liang HOU Yu State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong UniversityXi’an710049China Beijing Aerospace Technology Institute Beijing100083China

This paper proposed a new structure of highly-dense micro-jet arrays for hybrid jet-impingement/microchannel heat sinks(~120 jet per cm^(2) with jet width of 0.35 mm).Parametric study is performed to investigate the influence of structure and flow parameters on the convective heat transfer of water jet cooling in confined *** simulation results show that the optimal jet width,jet spacing and impingement distance are around 0.2 mm,0.2 mm and 0.3 mm,respectively,which can achieve a low thermal resistance as well as a relatively low pressure *** analysis of the heat transfer pathways shows that the micro-fin jet structures can extend the impinging heat transfer area and conduct a considerable proportion of heat,which can reach up to 38.9%with the Reynolds number ranging from 797.1 to *** heat transfer characteristics in the heat sink will shift from impingement dominated heat transfer to the channel-convection dominated heat transfer as the jet impingement distance increases.A correlation is proposed to predict the average Nusselt number on the stagnation area for the heat sink with different structure parameters,and the deviations of predictions from the numerical results are less than 10%.

关键词： hybrid heat sink impingement microchannel thermal management high heat flux

Shock Initiation Experiments with Modeling on a DNAN Based MeltCast Insensitive Explosive

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第2期32卷 655-662页

作者： Feichao miao Dandan Li Yangfan Cheng Junjiong Meng Lin Zhou School of Chemical Engineering Anhui University of Science and TechnologyHuainan 232001China Composite Explosive Research Department Xi'an Modern Chemistry Research InstituteXi'an 710065China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China

2,4-dinitroanisole(DNAN)is a good replacement for 2,4,6-trinitrotoluene(TNT)in melt-cast explosives due to its superior *** the increasing use of DNAN-based melt-cast explosives,the prediction of reaction violence and hazard assessment of the explosives subjected to shock is of great *** study investigated the shock initiation characteristics for a DNAN-based melt-cast explosive,DHFA,using the one-dimensional Lagrangian *** embedded manganin gauges in the apparatus record the pressure histories at four Lagrangian positions and show that shock-todetonation transition in DHFA needs a high input shock *** experimental data are analyzed to calibrate the Ignition and Growth *** calibration is performed using an objective function based on both pressure history and the arrival time of *** agreement between experimental and calculated pressure histories indicates the high accuracy of the calibrated parameters with the optimization method.

关键词： 2,4-Dinitroanisole(DNAN) Shock initiation Insensitive explosives Ignition and growth model Equation of state(EOS)

The effect of reactive plasticizer on viscoelastic and mechanical properties of solid rocket propellants based on different types of HTPB resin

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第3期33卷 66-77页

作者： Tihomir Kovacevic Slavko Mijatov Jelena Grzetic Suzana Cakic Bojana Fidanovski sasa Brzic Military Technical Institute Ministry of DefenceRatka Resanovica 1BelgradeSerbia Faculty of Technology University of NisBulevar osloboCenja 124LeskovacSerbia

Conventional plasticizers deteriorate mechanical and viscoelastic properties of the propellants due to their migration upon aging and long-term storage,which affects reliability and safety properties during *** address this issue,conventional plasticizer,dioctyl adipate(DOA),is replaced by reactive one,castor oil(CO).In addition,three different types of HTPB were used to obtain propellants with designed viscoelastic and mechanical *** CO increased propellants viscosity,without a significant impact on the propellant processability,regardless to the type of ***,mechanical properties were different depending on the type of resin,which were further analyzed by gel permeation chromatography(GPC).Addition of CO formed a denser polymer network and shifted T_(g) to higher values,compared to the compositions with *** tensile strength of CO-containing propellants was lower at +20℃ and +50℃ compared to the reference compositions,while the strain at maximum load and strain at break were significantly increased with pronounced plastic deformation,especially for samples at -30℃.The inclusion of CO in the propellants composition gives more room for adjusting a wide range of mechanical properties.

关键词： HTPB-based composite propellants Castor oil Reactive plasticizer Gel permeation chromatography Sol-gel analysis Mechanical and viscoelastic properties