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From MAFLD to hepatocellular carcinoma and everything in between

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Chinese Medical Journal 2022年第5期135卷 547-556页

作者： sarah da won bae Jacob George Liang Qiao Storr Liver Centre Westmead Institute for Medical ResearchUniversity of Sydney and Westmead HospitalWestmeadNSW 2145Australia

Metabolic(dysfunction)associated fatty liver disease(MAFLD),previously known as non-alcoholic fatty liver disease,is the most common cause of chronic liver disease *** risk factors contribute to the pathogenesis of MAFLD with metabolic dysregulation being the final arbiter of its development and *** poses a substantial economic burden to societies,which based on current trends is expected to increase over *** studies have addressed various aspects of MAFLD from its risk associations to its economic and social burden and clinical diagnosis and management,as well as the molecular mechanisms linking MAFLD to end-stage liver disease and hepatocellular *** review summarizes current understanding of the pathogenesis of MAFLD and related diseases,particularly liver *** therapeutic agents for MAFLD and diagnostic biomarkers are discussed.

关键词： Metabolic(dysfunction)associated fatty liver disease Liver disease Liver cancer

Prominent cycling reversibility and kinetics enabled by CaTiO3 protective layer on Zn metal for aqueous Zn-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 245-258页

作者： Gaeun Lee Yong Nam Ahn Seongjoon So Chanwoo Park Jong-Seong bae Taehyun Park Il Tae Kim Jaehyun Hur School of Chemical Biological and Battery Engineering Gachon University Seongnam Busan Center Korea Basic Science Institute

Aqueous Zn-ion batteries （AZIBs） have received considerable attention owing to their various advantages such as safety,low cost,simple battery assembly conditions,and high ionic ***,they still suffer from serious problems,including uncontrollable dendrite growth,corrosion,hydrogen evolution reaction （HER） from water decomposition,electrode passivation,and unexpected *** creation of a uniform artificial nanocrystal layer on the Zn anode surface is a promising strategy for resolving these ***,we propose the use of a perovskite CaTiO3（CTO） protective layer on Zn（CTO@Zn） as a promising approach for improving the performance of *** CTO artificial layer provides an efficient pathway for Zn ion diffusion towards the Zn metal because of the high dielectric constant （εr=180） and ferroelectric characteristics that enable the alignment of dipole moments and redistribute the Zn2+ions in the CTO *** avoiding the direct contact of the Zn anode with the electrolyte solution,the uneven dendrite growth,corrosion,parasitic side reactions,and HER are mitigated,while CTO retains its mechanical and chemical robustness during ***,CTO@Zn demonstrates an improved lifespan in a symmetric cell configuration compared with bare ***@Zn shows steady overpotential （～68 m V） for 1500 h at 1 mA cm-2/0.5 mA h cm-2,excelling bare ***,when paired with the V2O5-C cathode,the CTO@Zn//V2O5-C full battery delivers 148.4 mA h g-1（based on the mass of the cathode） after 300 *** study provides new insights into Zn metal anodes and the development of high-performance AZIBs.

关键词： Artificial layer Dielectric constant Zn metal anode Zinc aqueous battery

N-doped carbon-embedded TiN nanowires as a multifunctional separator for Li–S batteries with enhanced rate capability and cycle stability

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Journal of Energy Chemistry 2021年第6期30卷 10-18,I0001页

作者： Yoongon Kim Yuseong Noh Jaejin bae Hyunwoo Ahn Minho Kim won bae Kim Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)77 Cheongam-roNam-guPohang 37673South Korea

Lithium-sulfur(Li-S)batteries have attracted considerable attention as next-generation energy storage devices owing to their high theoretical specific capacity and ***,the commercialization of Li-S batteries is hindered by critical issues,including the migration of the dissolved lithium polysulfides(LiPSs)from the sulfur electrode to the lithium metal anode,resulting in poor cycling ***,we report a multifunctional interlayer configured with an N-doped carbon framework and titanium nitride nanowires on a polypropylene separator(NC/TiN NWs@PP)to suppress the polysulfide shuttling ***/TiN NWs@PP can be obtained by electrospinning and the subsequent scalable solution-based vacuum *** one-dimensional structure of the TiN NWs can shorten the Li-ion diffusion distance with large electrode/electrolyte ***,the N-doped carbon framework in the NWs enables facile electron transportation and allows the suppression of the shuttle effect to improve the electrochemical reaction *** Li-S battery with a NC/TiN NWs@PP separator exhibited enhanced cycling stability and rate capability,indicating that this could be a new research direction for Li-S batteries.

关键词： Li-S battery Shuttle effect Interlayer Separator TiN N-doped carbon 1D Nanowire

Recent progress in quasi-two-dimensional and quantum dot perovskite light-emitting diodes harnessing the diverse effects of ligands:A review

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Nano Research 2022年第7期15卷 6449-6465页

作者： Yurim bae Jun Ryu Saemon Yoon Dong-won Kang School of Energy Systems Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Smart City Chung-Ang UniversitySeoul 06974Republic of Korea

Halide perovskites have been extensively studied for use as light-emitting diodes(LEDs)in next-generation displays due to their beneficial characteristics,including their high color purity and wide color *** perovskites can be categorized into four representative structures:three-dimensional(3D)bulk,two-dimensional(2D),quasi-two-dimensional(quasi-2D),and quantum dot(QD).Recently,excellent advances in the performance of perovskite LEDs(PeLEDs),especially those with quasi-2D and QD architectures,have been demonstrated with the incorporation of organic chain *** can both modify the structure of PeLEDs,such as forming multi-quantum wells in quasi-2D PeLEDs and essential passivation layers in QD PeLEDs,and also enhance their optical *** appropriate use of ligands in PeLEDs can thus lead to greater luminescence,current efficiency,power efficiency,and external quantum *** this review,the principal roles of ligands in quasi-2D and QD PeLEDs are systematically ***,current limitations and future perspectives are discussed in detail.

关键词： perovskites light emitting diode ligands quasi-two-dimensional(quasi-2D) quantum dot

Implanting a preferential solid electrolyte interphase layer over anode electrode of lithium ion batteries for highly enhanced Li^+ diffusion properties

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Journal of Energy Chemistry 2020年第9期29卷 285-292,I0009页

作者： Ye Kyu Kim Yoongon Kim Jaejin bae Hyunwoo Ahn Yuseong Noh Hyunsu Han won bae Kim Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Nam-gu 37673PohangSouth Korea

The lithium-ion batteries are recognized as the most promising energy storage system,but it still does not meet the power requirements of electric vehicle batteries owing to low volumetric energy density with the traditional graphite electrode *** this study,we report the development of a novel electrode system fabricated by implantation of a solid electrolyte interphase(SEI)layer on the graphite *** SEI-implanted graphite electrode is made using a lithium bis(trifluoromethanesulfonyl)imide(LiTFSI)-based electrolyte and cycled with a lithium tetrafluoroborate LiBF4-based *** new electrode system shows significantly enhanced electrochemical properties owing to the rapid and efficient diffusion of Li ions through the SEI layer between the electrolyte and *** graphite electrode with its pre-formed SEI layer achieves a reversible capacity of 357 mAh g^-1 at 0.5 C after 50 cycles,which is significantly higher than that of commercial lithium-ion battery systems constructed with LiPF6(312mAh g^-1).The resulting unique electrode system could present a new avenue in SEI research for highperformance lithium-ion batteries.

关键词： SEI layer Graphite Implanting Li ion diffusion LiTFSI LiBF4 Artificial Mobility

Linking individual attributes and host specialization in brood parasitic cuckoos

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Avian Research 2022年第2期13卷 145-151页

作者： Sue-Jeong Jin Hae-Ni Kim Geun-won bae Jin-won Lee Jeong-Chil Yoo Korea Institute of Ornithology Kyung Hee UniversitySeoul02447Republic of Korea Department of Biology Kyung Hee UniversitySeoul02447Republic of Korea

Generalist avian brood parasites vary considerably in their degree of host specialization(e.g.,number of hosts);some parasitize the nests of just a few host species,whereas others exploit more than 100 *** factors,including habitat range,habitat type,and geographic location,have been suggested to account for these ***,inter-specific differences in individual attributes,such as personality and plasticity,have rarely been considered as potential factors of such variation,despite their potential relationship to,for example,range *** cage experiments,we tested the hypothesis that parasitic species exploiting more host species may be more active and *** this end,we quantified behaviors exhibited by two Cuculus cuckoos(Common Cuckoo *** and Oriental Cuckoo ***)that vary greatly in their number of host ***,we evaluated exploratory behavior displayed by birds in the cage,such as the number of movements,head-turning,wing-flapping,and *** Common Cuckoo,which has a higher number of host species,tended to exhibit higher levels of exploratory behaviors than the Oriental *** study showed that the two cuckoo species exhibited different exploratory levels,as predicted by the differences in their number of *** studies regarding the causality between individual attributes and host specialization with improved experimental methodology would greatly enhance our understanding of the role of individual characteristics in the coevolution of avian brood parasites and their hosts.

关键词： Brood parasitism Common Cuckoo Individual attributes Number of hosts Oriental Cuckoo

Effects of casting speed on microstructure and segregation of electromagnetically stirred Aluminum alloy in continuous casting process

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Rare Metals 2006年第z2期25卷 118-123页

作者： LEE Dock-Young KANG Suk-won CHO Duck-Ho KIM Ki-bae Division of Materials Korea Institute of Science and Technology P.O. Box 131 Cheongryang Seoul 130-650 Korea Department of Applied Materials Engineering Hanbat National University Daejeon 305-719 Korea

Recently, a semi-solid metal processing has been acknowledged as a cost-effective technique to be able to manufacture high quality product for the transportation industry. In this study a hypo-eutectic Al alloy was fabricated by means of an electromagnetic stirrer in continuous casting process and the microstructural change during solidification due to a fluid flow by electromagnetic stirring was examined. Due to the forced fluid flow during solidification a dendritic phase of primary α phase of Al alloy was turned into a globular phase, which can make the Al alloy get a thixotropic behavior in the semi-solid region. In order to establish the quantitative relationship between microstructure and the process parameters, the morphology shape, a silicon distribution and a size of primary α phase were observed according to casting speed in continuous casting machine. The primary α phase was turned into the degenerate dendrites approaching a spherical configuration with increasing casting speed. The fine-grained and equiaxed microstructure appeared at higher casting speed. A segregation behavior of Si element was declined with increasing casting speed and a very uniform distribution of Si element was observed on the billet at a casting speed of 600 mm·min-1. A thickness of the solidifying shell of the billet was shortened with increasing the casting speed.

关键词： semi-solid slurry electromagnetic stirring casting speed segregation Al alloy

Venous adventitial cystic disease is a very rare disease that can cause deep vein thrombosis:A case report

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World Journal of Clinical Cases 2023年第34期11卷 8170-8175页

作者： Miju bae Up Huh Chung won Lee Jong won Kim Department of Thoracic and Cardiovascular Surgery Pusan National University School of MedicineBusan 49241South Korea Biomedical Research Institute Pusan National University HospitalBusan 49241South Korea

BACKGROUND Venous adventitial cystic disease(VACD)is a rare disease characterized by cysts,filled with a gelatinous mucous substance similar to joint fluid,in the adventitia of blood vessels adjacent to the *** is often misdiagnosed as deep vein thrombosis(DVT),femoral varices,venous tumors,or *** SUMMARY A 69-year-old woman visited our hospital with a complaint of swelling in the right lower *** patient was diagnosed with DVT and prescribed apixaban at an outpatient *** 3 wk,the patient was hospitalized again because of sudden swelling in the right lower *** diagnosed VACD and performed surgery for cyst removal as well as patch angioplasty and thrombectomy of the right common femoral *** patient received anticoagulants for 6 mo and has been doing well without recurrence for 1 year *** Recurrent VACD requires complete removal of the connections to the joint cavity to prevent recurrence.

关键词： Adventitia Cysts Edema Joints Venous thrombosis Case report

Effects of Al addition on microstructure and mechanical properties of extruded Mg-3Bi alloy

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Journal of Magnesium and Alloys 2022年第7期10卷 1887-1898页

作者： Sang-Cheol Jin Jae won Cha Jun Ho bae Hui Yu Sung Hyuk Park School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Implementation Research Division Korea Institute of Materials ScienceChangwon 51508Republic of Korea School of Materials Science and Engineering Hebei University of TechnologyTianjin 300130China

Effects of Al addition to a Mg±Bi binary alloy on its microstructural characteristics and tensile properties after extrusion are investigated via extrusion of Mg-3Bi±x Al(x=0,1,and 2 wt%)billets and analysis of the extruded *** Al addition negligibly affects the second-phase particles of the extruded alloy;however,an increase in the Al content causes significant decreases in the average grain size and maximum texture intensity of the extruded material owing to an increase in the area fraction of dynamically recrystallized(DRXed)*** Al addition improves the strength of the extruded alloy;this improvement is attributed to the enhanced grain-boundary hardening and solid-solution hardening effects induced by grain refinement and Al solute atoms,*** the Al content increases from 0 wt%to 1 wt%and 2 wt%,the tensile elongation increases substantially from 2.8%to 9.4%and 16.9%,*** reduction in the number and size of un DRXed grains with increasing Al content suppresses the formation and coalescence of cracks in the un DRXed grains during tension,which results in a significant improvement in the tensile ductility of the extruded *** tensile deformation,large undesirable twins that act as crack initiation sites are locally formed in the un DRXed grains of the Mg-3Bi alloy,whereas relatively smaller twins are uniformly formed in both the DRXed and the un DRXed grains of the Mg-3Bi-2Al ***,the extruded Mg-3Bi-2Al alloy has a substantially higher tensile yield strength±elongation product(2924 MPa%)than the extruded Al-free B3 alloy(381 MPa%).

关键词： Mg-Bi-Al alloy Extrusion Microstructure Strength Ductility