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Solid-state impedance spectroscopy studies of dielectric properties and relaxation processes in Na_(2)O–V_(2)O_(5)–Nb_(2)O_(5)–P_(2)O_(5) glass

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International Journal of minerals,metallurgy and materials 2024年第1期31卷 186-196页

作者： sara marijan Luka Pavic Division of materials Chemistry Ruđer Boskovic InstituteBijenicka 54HR-10000 ZagrebCroatia

Solid-state impedance spectroscopy(SS-IS)was used to investigate the influence of structural modifications resulting from the addition of Nb2O5 on the dielectric properties and relaxation processes in the quaternary mixed glass former(mGF)system 35Na_(2)O–10V_(2)O_(5)–(55-x)P_(2)O_(5)–xNb_(2)O_(5)(x=0–40,mol%).The dielectric parameters,including the dielectric strength and dielectric loss,are determined from the frequency and temperature-dependent complex permittivity data,revealing a significant dependence on the Nb2O5 *** transition from a predominantly phosphate glass network(xmixed niobate–phosphate glass net-work(10≤x≤20,region II)leads to an increase in the dielectric parameters,which correlates with the observed trend in the direct-cur-rent(DC)*** the predominantly niobate network(x≥25,region III),the highly polarizable nature of Nb5+ions leads to a fur-ther increase in the dielectric permittivity and dielectric *** is particularly evident in Nb-40 glass-ceramic,which contains Na_(13)Nb_(35)O_(94) crystalline phase with a tungsten bronze structure and exhibits the highest dielectric permittivity of 61.81 and the lowest loss factor of 0.032 at 303 K and 10 *** relaxation studies,analyzed through modulus formalism and complex impedance data,show that DC conductivity and relaxation processes are governed by the same mechanism,attributed to ionic *** contrast to glasses with a single peak in frequency dependence of imaginary part of electrical modulus,m″(ω),Nb-40 glass-ceramic exhibits two distinct contributions with similar relaxation *** high-frequency peak indicates bulk ionic conductivity,while the additional low-fre-quency peak is associated with the grain boundary effect,confirmed by the electrical equivalent circuit(EEC)*** scaling characteristics of permittivity and conductivity spectra,along with the electrical modulus,validate time-temperature superposition and demonstrate a

关键词： phosphate glasses glass-ceramics impedance spectroscopy dielectric properties relaxation processes permittivity scaling conductivity scaling modulus formalism

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metal-Halide Perovskite Submicrometer-Thick Films for Ultra-Stable Self-Powered Direct X-Ray Detectors

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Nano-micro Letters 2024年第9期16卷 410-431页

作者： marco Girolami Fabio matteocci sara Pettinato Valerio Serpente Eleonora Bolli Barbara Paci Amanda Generosi Stefano Salvatori Aldo Di Carlo Daniele m.Trucchi CNR‑ISm Consiglio Nazionale delle RicercheIstituto di Struttura della MateriaSede Secondaria di MontelibrettiDiaTHEMA LabStrada Provinciale 35D900010 MontelibrettiRomeItaly CHOSE–Centre for Hybrid and Organic Solar Energy Department of Electronic EngineeringUniversity of Rome“Tor Vergata”Via del Politecnico 100133 RomeItaly Faculty of Engineering Universita degli Studi Niccolo CusanoVia don Carlo Gnocchi 300166 RomeItaly SpecXLab CNR‑ISMConsiglio Nazionale Delle RicercheIstituto di Struttura Della MateriaArea della Ricerca di Tor VergataVia del Fosso del Cavaliere 10000133 RomeItaly

metal-halide perovskites are revolutionizing the world of X-ray detectors,due to the development of sensitive,fast,and cost-effective ***-powered operation,ensuring portability and low power consumption,has also been recently demonstrated in both bulk materials and thin ***,the signal stability and repeatability under continuous X-ray exposure has only been tested up to a few hours,often reporting degradation of the detection *** it is shown that self-powered direct X-ray detectors,fabricated starting from a FAPbBr_(3)submicrometer-thick film deposition onto a mesoporous TiO_(2)scaffold,can withstand a 26-day uninterrupted X-ray exposure with negligible signal loss,demonstrating ultra-high operational stability and excellent *** structural modification is observed after irradiation with a total ionizing dose of almost 200 Gy,revealing an unexpectedly high radiation hardness for a metal-halide perovskite thin *** addition,trap-assisted photoconductive gain enabled the device to achieve a record bulk sensitivity of 7.28 C Gy^(−1)cm^(−3)at 0 V,an unprecedented value in the field of thin-film-based photoconductors and photodiodes for“hard”***,prototypal validation under the X-ray beam produced by a medical linear accelerator for cancer treatment is also introduced.

关键词： metal-halide perovskite thin films Direct X-ray detectors Self-powered devices Operational stability medical linear accelerator

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Demographic and socioeconomic determinants of urinary arsenic concentration for elementary school children in Bangladesh

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Global Health Journal 2024年第3期8卷 119-127页

作者： Raisa sara Khalid m.Khan Shelbin mattathil munachimso Nwankwo mohammad Aminul Islam Faruque Parvez Department of Economics and International Business College of Business AdministrationSam Houston State UniversityHuntsvilleTX 77340USA Department of Public Health College of Health SciencesSam Houston State UniversityHuntsvilleTX 77340USA College of Osteopathic medicine Sam Houston State UniversityConroeTX 77304USA Paul G.Allen School for Global Health Washington State UniversityPullmanWA 99164USA Department of Environmental Health Mailman School of Public HealthColumbia UniversityNew YorkNY 10032USA

Background:Arsenic(As)is a toxic element that can lead to various health issues in *** primary exposure to As is through the consumption of water contaminated with high As levels,particularly in *** studies have shown that urinary arsenic(UAs)concentration can reflect As exposure and metabolism in ***,little is known about how other factors,such as age,sex,and socioeconomic status,may affect UAs concentrations in ***:This study aimed to investigate the influence of factors such as age,sex,and socioeconomic status on UAs concentrations in children,in addition to the impact of drinking water arsenic(WAs)***:We conducted our study on elementary school-going children aged 8-11 years from rural Araihazar in *** measured UAs(available for a subset of 391 children)and WAs levels and collected information on demographic and socioeconomic *** employed regression analysis and t-tests to analyze the ***:Our findings revealed that younger children(β=197.95,95%confidence interval[CI]:111.97 to 283.94),female children(β=93.95,95%CI:8.49 to 179.40),and children with less educated fathers(β=138.03,95%CI:26.47 to 249.58)had higher UAs levels,particularly when they consumed water with high As ***:The study concludes that children's As exposure and UAs concentration may vary depending on their age,sex,and socioeconomic ***,these factors should be considered when assessing the health risks associated with As.

关键词： Waterarsenic Rural children Socioeconomicfactors Bangladesh

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Development and assessment of artificial neural network models for direct normal solar irradiance forecasting using operational numerical weather prediction data

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Energy and AI 2024年第1期15卷 88-101页

作者： sara Pereira Paulo Canhoto Rui Salgado Institute of Earth Sciences University ofÉvoraRua Romãao Ramalho 597000-671ÉvoraPortugal Department of mechatronics Engineering University of´EvoraRua Romãao Ramalho 597000-671ÉvoraPortugal Physics Department University of´EvoraRua Romãao Ramalho 597000-671ÉvoraPortugal

Accurate operational solar irradiance forecasts are crucial for better decision making by solar energy system operators due to the variability of resource and energy *** numerical weather prediction(NWP)models can forecast solar radiation variables,they often have significant errors,particularly in the direct normal irradiance(DNI),which is especially affected by the type and concentration of aerosols and *** paper presents a method based on artificial neural networks(ANN)for generating operational DNI forecasts using weather and aerosol forecasts from the European Center for medium-range Weather Forecasts(ECmWF)and the Copernicus Atmospheric monitoring Service(CAmS),*** ANN models were designed:one uses as input the predicted weather and aerosol variables for a given instant,while the other uses a period of the improved DNI forecasts before the forecasted *** models were developed using observations for the location of´Evora,Portugal,resulting in 10 min DNI forecasts that for day 1 of forecast horizon showed an improvement over the downscaled original forecasts regarding R2,mAE and RmSE of 0.0646,21.1 W/m^(2)and 27.9 W/m^(2),*** model was also evaluated for different timesteps and locations in southern Portugal,providing good agreement with experimental data.

关键词： Solar radiation Solar energy Numerical weather prediction Artificial neural network Operational forecasting

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In silico identification of antiviral compounds for the treatment of chikungunya virus infection:qsar modelling and md simulation analysis

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medicine in Novel Technology and Devices 2024年第2期22卷 102-114页

作者： Hayder m Abdulhamza muthanna S.Farhan sara.S Hassan Hany Aqeel Al-Hussainy Amjad Ibrahim Oriabi Department of Pharmacy Kut University CollegeAlkutWasit52001Iraq Department of Pharmaceutical Chemistry College of PharmacyUniversity of BaghdadBaghdadIraq Al-manara College for medical Sciences Department of PharmacyIraq Department of Pharmacy Hilla University CollegeBabylonIraq Dr Hany Akeel Institute Iraqi Medical Research CenterBaghdad10001Iraq

Chikungunya virus(CHIKV),transmitted by arthropods,has gained global recognition for its impact on public *** has expanded globally,including Africa,Asia,and the Indian subcontinent,and has a helicase protein in its genome that is crucial for its ***,the study targeted the helicase protein of CHIKV with 745 antiviral compounds using an mL-based QSAR model and molecular *** binders(5279172,78161839,6474310,and 5330286)were selected for mD simulation based on the control(Silvestrol).All compounds had the highest binding scores,with 78161839 showing the most consistent RmSD and the least conformational variation,indicating high *** also showed the lowest binding free energy(ΔG¼31.31 kcal/mol),indicating energetically favourable *** and FEL also depicted the stable complex confirmation of the protein and 78161839 complex during the 100 ns ***,this study aimed to identify helicase function antiviral binders that could be experimentally tested for treating CHIKV.

关键词： Chikungunya virus machine learning based QSAR molecular dynamic solution Helicase

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Percutaneous nephrostomy versus ureteral stent in hydronephrosis secondary to obstructive urolithiasis:A systematic review and meta-analysis

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Asian Journal of Urology 2024年第2期11卷 261-270页

作者： Andreia Cardoso Aparício Coutinho Gonçalo Neto sara Anacleto Catarina Laranjo Tinoco Nuno morais mário Cerqueira-Alves Estevão Lima Paulo mota Department of Urology Hospital de BragaBragaPortugal School of medicine University of MinhoBragaPortugal Association(2CA-Braga).School of medicine University of MinhoBragaPortugal

Objective: To assess if there is a preferable intervention between retrograde ureteral stent (RUS) and percutaneous nephrostomy (PCN) tube, in cases of upper urinary tract stone obstruction with complications requiring urgent drainage, by evaluating outcomes regarding urinary symptoms, quality of life (QoL), spontaneous stone passage, and length of hospital stays, since there is no literature stating the superiority of one modality over the ***: We searched mEDLINE and other sources for relevant articles in June 2019 without any date restrictions or filters applied. The selection was done first by the title and abstract screening and then by full-text assessment for eligibility. Only randomized controlled trials or cohort studies in patients with hydronephrosis secondary to obstructive urolithiasis that presented comparative data between PCN and RUS placement concerning at least one of the defined outcome measures were included. Lastly, mEDLINE database and Pubmed platform were screened again using the same terms, from June 2019 until November ***: Of 556 initial articles, seven were included in this review. most works were considered of moderate-to-high quality. Three studies regarding QoL showed a tendency against stenting, even though only one demonstrated statistically significant negative impact on overall health state. Two works reported significantly more post-intervention urinary symptoms in stenting patients. One article found that PCN is a significant predictor of spontaneous stone passage, when adjusted for stone size and location. Findings on length of hospital stays were not consistent among ***: PCN appears to be the intervention better tolerated, with less impact on the patient’s perceived QoL and less post-operative urinary symptoms, in comparison with RUS. Nevertheless, further studies with larger samples and a randomized controlled design are suggested.

关键词： Ureteral stent Percutaneous nephrostomy Obstructive urolithiasis Urinary symptoms Quality of life

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Stabilisation of estuarine sediments with an alkali-activated cement for deep soil mixing applications

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Journal of Rock mechanics and Geotechnical Engineering 2024年第4期16卷 1398-1410页

作者： Claver Pinheiro sara Rios António Viana da Fonseca Nuno Cristelo Centre of Physics of minho and Porto Universities (CF-Um-UP) Azurém CampusUniversity of MinhoGuimarães4800-058Portugal CONSTRUCT-GEO Faculty of EngineeringUniversity of PortoRua Dr.Roberto FriasPortos/n 4200-465Portugal CQ-VR School of Science and TechnologyUniversity of Trás-os-Montes e Alto DouroVila Real5000-801Portugal

In this work,an alternative alkali-activated cement(AAC)made of ladle slag precursor mixed with sodium hydroxide and sodium silicate has been developed to enhance the bearing capacity of estuarine soils in coastal conditions via deep soil mixing(DSm).The AAC was optimized to use a low reactivity precursor(ladle slag)and to deal with a contaminated high-water content natural sediment cured under *** material performance was analysed by comparison to a mixture made with Portland cement and cured in the same *** and unconfined compressive strength tests as well as seismic waves measurements after 3-,7-,14-and 28-d curing were performed to obtain a relationship between elastic stiffness and strength with curing time for both ***,the AAC mix demonstrated superior strength results,exhibiting almost double flexural and compressive strengths after 28 d compared to the Portland cement *** AAC mix also showed a higher rate of stiffness increase than the Portland cement mix,which has a higher initial stiffness at young ages but lower stiffness *** analysis confirmed that the proposed AAC could effectively immobilise any contaminants from soil or *** effect of curing under stress was analysed in triaxial compression tests and found to be insignificant,indicating that laboratory data obtained without stress curing can represent the material's behaviour in a DSm column,which will cure under the weight of the column.

关键词： Alkaline-activation Steel slag Submerged curing Seismic wave measurements Leachate analysis Curing under stress

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Seroprevalence Survey of HIV and Hepatitis B Virus and Behavioral Characteristics among Heavy Truck Drivers along Port Sudan-Khartoum Highways

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Open Journal of medical microbiology 2024年第1期14卷 11-22页

作者： sara S. Osman Adam A. mattar Omnia m. Hamid Faculty of Public Health Alzaiem Alazhari University Khartoum Sudan Faculty of medical Laboratory Sciences University of Medical Sciences & Technology Khartoum Sudan

The prevalence of human immunodeficiency virus (AIDS) and hepatitis B virus among heavy truck drivers and their assistants has been well documented globally in correlation with their behavioral characteristics. The present study aimed to screen for human immunodeficiency virus (HIV), hepatitis B virus (HBV), and behavioral characteristics among heavy truck drivers in Port Sudan. A cross-sectional study was conducted on 274 heavy truck drivers and their assistants who used the highway Port Sudan-Khartoum in Port Sudan city during 2019-2021. Data on behavioral characteristics and substance use habits were collected using a structured questionnaire, and an ELISA test was used to screen for HIV and HBV infections in the study participants. The chi-square test, odds ratio, and confidence intervals were used to find the association between behavioral characteristics and seropositive HIV/HBV. Of the 274 enrolled participants, the seroprevalence rates of HIV were 2.7% and HBV was 23.7%. Ninety-four (34.3%) of them had a history of high-risk sexual behavior outside of marriage;only two (0.7%) used condoms;14.2% of participants reported alcohol use;and 1.1% reported drug use. Univariate analysis revealed that having a sex history outside of marriage with ≥1 sex partner and never using a condom with a spouse or casual partner were significant risk factors for HIV and HBV among drivers. Fortunately, we found that most of the drivers reported low alcohol and drug use. Concerning this study, the seroprevalence of HIV and HBV is highly associated with a history of having sex outside of marriage and sexual behavior among truck drivers and assistances. Additional studies are needed to further investigate other STIs and behavioral characteristics associated with factors in truck drivers/assistance in different truck stop regions in Sudan.

关键词： Sexual Transmitted Infection Port Sudan Truck Drivers/Assistance

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Rethinking neurodegenerative diseases:neurometabolic concept linking lipid oxidation to diseases in the central nervous system

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Neural Regeneration Research 2024年第7期19卷 1437-1445页

作者： Steinunn sara Helgudóttir Anne Skøttrup mørkholt Jacek Lichota Preben Bruun-Nyzell mads Christian Andersen Nanna marie Juhl Kristensen Amanda Krøger Johansen mikela Reinholdt Zinn Hulda maria Jensdóttir John Dirk Vestergaard Nieland 2N Pharma ApS NOVI Science ParkAalborgDenmark molecular Pharmacology Group Department of Health Science and TechnologyAalborg UniversityAalborgDenmark

Currently,there is a lack of effective medicines capable of halting or reve rsing the progression of neurodegenerative disorde rs,including amyotrophic lateral sclerosis,Parkinson s disease,multiple sclerosis,or Alzheimer s *** the unmet medical need,it is necessary to reevaluate the existing para digms of how to to rget these *** considering neurodegenerative diseases from a systemic neurometabolic perspective,it becomes possible to explain the shared pathological *** innovative approach presented in this paper draws upon exte nsive research conducted by the authors and researchers *** this review,we highlight the importance of metabolic mitochondrial dysfunction in the context of neurodegenerative *** provide an overview of the risk factors associated with developing neurodegenerative disorders,including genetic,epigenetic,and environmental fa ***,we examine pathological mechanisms implicated in these diseases such as oxidative stress,accumulation of misfolded proteins,inflammation,demyelination,death of neurons,insulin resistance,dysbiosis,and neurotransmitter ***,we outline a proposal for the restoration of mitochondrial metabolism,a crucial aspect that may hold the key to facilitating curative therapeutic interventions for neurodegenerative disorders in forthcoming advancements.

关键词： brain disease carnitine palmitoyl transferase 1 epigenetics metabolism gut microbiome mitochondrial dysfunction neurodegeneration oxidative stress

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Storylines of family medicine Ⅶ: family medicine across the lifespan

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Family medicine and Community Health 2024年第S3期12卷 61-69页

作者： William B Ventres Leslie A Stone Katharine C Barnard sara G Shields mark J Nelson maria Verónica Svetaz Clara m Keegan Joel J Heidelbaugh Paige B Beck Lucille marchand Family and Preventive medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family medicine and Community Health UMass Chan Medical SchoolWorcesterMassachusettsUSA John Peter Smith Hospital Family medicine Residency Fort WorthTexasUSA Family and Community medicine Hennepin HealthcareMinneapolisMinnesotaUSA Family medicine University of Vermont Larner College of MedicineBurlingtonVermontUSA Family medicine University of Michigan Medical SchoolAnn ArborMichiganUSA Family medicine and Community Health University of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA

Storylines of Family medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅶ:family medicine across the lifespan’,authors address the following themes:‘Family medicine maternity care’,‘Seeing children as patients brings joy to work’,‘Family medicine and the care of adolescents’,‘Reproductive healthcare across the lifespan’,‘men’s health’,‘Care of older adults’,and‘Being with dying’.may readers appreciate the range of family medicine in these essays.

关键词： life illustration family

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