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Different behavioral profles between invasive and native nudibranchs:means for invasion success?

Current Zoology 2024年第3期70卷 406-417页

作者： Armando Macali sara ferretti Serena Scozzafava Elia Gatto Claudio Carere Ichthyogenic Experimental Marine Centre(CISMAR) Department of Ecological and Biological SciencesTuscia University01016 Borgo Le SalineTarquiniaItaly Department of Chemical Pharmaceutical and Agricultural SciencesFerrara Universityvia Luigi Borsari 4644121 FerraraItaly Department of Life Sciences and Biotechnology Ferrara Universityvia Luigi Borsari 4644121 FerraraItaly

Behavior is predicted to be a primary determinant of the success of the invasion process during the early phases of *** invaders with sympatric native species may provide a good approach to unravel behavioral traits involved in an invasion *** this study,we carried out an experimental simulation of the introduction and the acclimatization phase into a new environment and assessed the expression of activity,alertness,and habituation in an invasive Mediterranean population of the South African nudibranch Godiva quadricolor comparing its profles with those of the sympatric Mediterranean native nudibranchs Cratena peregrina and Caloria *** of these 3 species were subjected to 3 behavioral tests:spontaneous activity,carried out in the introduction phase(immediately after sampling)and after a week of acclimatization;alert test,in which a potential threat was simulated by means of a tactile stimulus,and habituation test,in which the same alert test stimulus was repeated 5 times at 30-min *** invasive *** showed higher levels of exploration activity,thigmotaxis,alertness,and sensitization than the native *** behavioral traits may represent pivotal drivers of the ongoing invasion process.

关键词： biological invasion invasive phenotype invertebrate cognition molluscs personality

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Liver-side of inflammatory bowel diseases:Hepatobiliary and druginduced disorders

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World Journal of Hepatology 2021年第12期13卷 1828-1849页

作者： Stefano Mazza sara Soro Maria Chiara Verga Biagio Elvo Francesca ferretti Fabrizio Cereatti Andrea Drago Roberto Grassia Gastroenterology and Digestive Endoscopy Unit ASST CremonaCremona 26100Italy Gastroenterology Unit ASST Fatebenefratelli-SaccoDepartment of Biomedical and Clinical Sciences(DIBIC)Universitàdegli Studi di MilanoMilan 20157Italy

Hepatobiliary disorders are among the most common extraintestinal manifestations in inflammatory bowel diseases(IBD),both in Crohn’s disease and ulcerative colitis(UC),and therefore represent a diagnostic *** conditions include primary sclerosing cholangitis(PSC)as the main form,variant forms of PSC(namely small-duct PSC,PSC-autoimmune hepatitis overlap syndrome and IgG4-related sclerosing cholangitis)and granulomatous *** is by far the most common,presenting in up to 8%of IBD patients,more frequently in *** genetic foci have been identified,but environmental factors are preponderant on disease *** course of the two diseases is typically *** diagnosis is based mostly on typical radiological findings and exclusion of secondary *** of cholangiocarcinoma is significantly increased in PSC,as well as the risk of colorectal cancer in patients with PSC and IBD-related *** disease-modifying drugs are approved to ***,PSC management is directed against symptoms and complications and includes medical therapies for pruritus,endoscopic treatment of biliary stenosis and liver transplant for end-stage liver *** nonimmune-mediated hepatobiliary disorders are gallstone disease,whose incidence is higher in IBD and reported in up to one third of IBD patients,non-alcoholic fatty liver disease,pyogenic liver abscess and portal vein *** liver injury(DILI)is an important issue in IBD,since most IBD therapies may cause liver toxicity;however,the incidence of serious adverse events is *** and methotrexate are the most associated with DILI,while the risk related to anti-tumor necrosis factor-αand anti-integrins is *** on hepatotoxicity of newer drugs approved for IBD,like anti-interleukin 12/23 and tofacitinib,are still scarce,but the evidence from other rheumatic diseases is *** B reactivation during immunosuppressive therapy is a major

关键词： Inflammatory bowel diseases Hepatobiliary disorders Primary sclerosing cholangitis Drug-induced liver injury Biological drugs Viral hepatitis

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