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Controlling infestation of a chocolate factory by Plodia interpunctella by combining mating disruption and the parasitoid Habrobracon hebetor

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Insect Science 2017年第3期24卷 503-510页

作者： Pasquale Trematerra Annachiara Oliviero sara Savoldelli Matthias Scholler Department of Agricultural Environmental and Food Sciences University of Molise Via De Sanctis 86100 Campobasso Italy Department of Food Environmental and Nutritional Sciences Universit& degli Studi di Milano Via Celoria 2 20133 Milan Italy Faculty of Life Sciences Humboldt-Universit#t zu Berlin Lentzeallee 55/57 14195 Berlin Germany

A field experiment of 4 years＇ duration was carried out to evaluate the ef- ficacy of combining the mating disruption （MD） formulation Dismate ZETA （（9Z,12E）- tetradecadienyl acetate）, with the parasitoid Habrobracon hebetor against the Indianmeal moth Plodia interpunctella in a chocolate factory. The experimental period began early in 2011 and ended in late 2014. Begane Dismate dispensers were placed in the facility from 2011 to 2014 and H. hebetor was released in 2014. Pheromone-baited traps were used to monitor the flight activity of the male moths and oviposition Petri dish traps were placed to assess the progeny production ofP. interpunctella females. Following the start of MD, a decrease in the number ofP. interpunctella males caught in monitoring traps was observed from 2011 to 2013. A further decline in the moth population was noted in 2014, when MD was combined with the release of parasitoids. The presence of larvae in the oviposition cups was occasionally observed throughout the monitoring period, from 2011 to 2014. This study demonstrates that the combined system of MD and parasitoids is an effective and reliable technique that can be used to successfully control P. interpunctella.

关键词： control food processing integrated pest management mating disruption parasitoid Plodia interpunctella

Prediction of Proteins Associated with COVID-19 Based Ligand Designing and Molecular Modeling

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Computer Modeling in Engineering & Sciences 2020年第12期125卷 907-926页

作者： Majid Monajjemi Rahim Esmkhani Fatemeh Mollaamin sara Shahriari Department of Chemical Engineering Central Tehran BranchIslamic Azad UniversityTehran14987-54891Iran Department of Chemistry Khoy BranchIslamic Azad UniversityKhoy58159-88838Iran Department of Chemistry Central Tehran BranchIslamic Azad UniversityTehran***Iran

Current understanding about how the virus that causes COVID-19 spreads is largely based on what is known about similar *** of the Natural products are suitable drugs against SARS-CoV-2 main *** recognizing a strong inhibitor,we have accomplished dock-ing studies on the major virus protease with 4 natural product species as anti COVID-19(SARS-CoV-2),namely“Vidarabine”,“Cytarabine”,“Gem-citabine”and“Matrine”which have been extracted fromGillan’s leaves *** are known as Chuchaq,Trshvash,Cote-Couto and Khlvash in *** these four studied compounds,Cytarabine appears as a suitable com-pound with high effectiveness inhibitors to this *** by this work we present a method on the Computational Prediction of Protein Structure Associated with COVID-19 Based Ligand Design and Molecular *** this investigation,auto dock software(iGEM-DOCK)has been used and via this tool,the suitable receptors can be distinguished in whole COVID-19 component structures for forming a complex.“iGEMDOCK”is suitable to define the binding site *** docking simulation and NMR inves-tigation,we have demonstrated these compounds exhibit a suitable binding energy around 9 Kcal/mol with various ligand proteins modes in the bind-ing to COVID-19 ***,these data need further evaluation for repurposing these drugs against COVID-19 viruses,in both vivo&vitro.

关键词： COVID-19 receptor binding domain Gillan’s leaves plants angiotensin converting enzyme-2 protease domain

Geospatial susceptibility mapping of earthquake-induced landslides in Nuweiba area, Gulf of Aqaba, Egypt

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Journal of Mountain Science 2016年第7期13卷 1286-1303页

作者： sara ABUZIED Samia IBRAHIM Mona KAISER Tarek Saleem Center for Spatial Analysis University of Oklahoma Geology Departments Faculty of Science Suez Canal University

Earthquake induced landslides are one of the most severe geo-environmental hazards that cause enormous damage to infrastructure, property, and loss of life in Nuweiba area. This study developed a model for mapping the earthquake-induced landslide susceptibility in Nuweiba area in Egypt with considerations of geological, geomorphological, topographical, and seismological factors. An integrated approach of remote sensing and GIS technologies were applied for that target. Several data sources including Terra SAR-X and SPOT 5 satellite imagery, topographic maps, field data, and other geospatial resources were used to model landslide susceptibility. These data were used specifically to produce important thematic layers contributing to landslide occurrences in the region. A rating scheme was developed to assign ranks for the thematic layers and weights for their classes based on their contribution in landslide susceptibility. The ranks and weights were defined based on the knowledge from field survey and authors experiences related to the study area. The landslide susceptibility map delineates the hazard zones to three relative classes of susceptibility: high, moderate, and low. Therefore, the current approach provides a way to assess landslide hazards and serves for geo-hazard planning and prediction in Nuweiba area.

关键词： Geographic Information Systems(GIS) Remote Sensing(RS) Landslides Susceptibility mapping Weights Nuweiba area

Long-term experience with debulking surgery in extensive hepatic alveolar echinococcosis:A case series and literature review

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Asian Pacific Journal of Tropical Medicine 2022年第10期15卷 468-473页

作者： Mohsen Aliakbarian Marcello Di Martino sara Saeidi Department of General Surgery Surgical Oncology Research CenterMashhad University of Medical SciencesMashhadIran Division of Hepatobiliary and Liver Transplantation Surgery.A.O.R.N.Cardarelli NapoliItaly

Objective:To assess the role of debulking surgery in extensive hepatic alveolar echinococcosis(HAE).Methods:Five cases of extensive HAE undergoing debulking surgery with their long-term follow-ups were ***,a systematic review was carried ***:The average age of patients in the study was(50.8±17.1)years(range 36 to 77 years).Three cases were *** median follow-up period was 61 months(range 12 to 84 months).Left liver resections were performed in 2 cases and right hemihepatectomies were undertaken in 2 *** patients(cases 2 and 4)developed early surgical complications,while one of them(case 4)who suffered from the recurrent sub-hepatic abscess died at 12 months ***:This study highlights the importance of debulking surgery for the management of complex symptomatic HAE lesions in patients with no curative option available.

关键词： Alveolar echinococcosis Debulking surgery Reduction Palliative Echinoccocosis multilocularis Case series

To resect or not to resect?-the dilemma in oligometastatic breast cancer

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 623-625页

作者： sara Lonardi Valentina Guarneri Medical Oncology 3 Istituto Oncologico Veneto IOV-IRCCSPaduaItaly Department of Surgery Oncology and GastroenterologyUniversity of PaduaPaduaItaly Medical Oncology 2 Istituto Oncologico Veneto IOV-IRCCSPaduaItaly

Despite the good prognosis of the vast majority of breast cancer cases,about 10%is firstly diagnosed with stage IV,while 20-30%of localized disease treated with curative intent will eventually relapse(1).Hepatic metastases are the third site of relapse,after lymph-nodes and bone,but,due to the early systemic nature of breast cancer,rarely the recurrence is liver-limited.

关键词： breast cancer prognosis

Magnetic resonance imaging for prostate cancer before radical and salvage radiotherapy: What radiation oncologists need to know

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World Journal of Clinical Oncology 2017年第4期8卷 305-319页

作者： Felipe Cou?ago Gemma Sancho Violeta Catalá Diana Hernández Manuel Recio sara Montemui?o Jhonathan Alejandro Hernández Antonio Maldonado Elia del Cerro Department of Radiation Oncology Hospital Universitario Quirónsalud Madrid Clinical Department Faculty of BiomedicineUniversidad Europea Department of Radiation Oncology Hospital de la Santa Creu i Sant Pau Department of Radiology Fundació Puigvert Department of Radiology Hospital de la Santa Creu i Sant Pau Department of Radiology Hospital Universitario Quirónsalud Madrid Department of Radiation Oncology Hospital Universitario de Fuenlabrada Department of Nuclear Medicine Hospital Universitario Quirónsalud Madrid

External beam radiotherapy(EBRT) is one of the principal curative treatments for patients with prostate cancer(PCa). Risk group classification is based on prostate-specific antigen(PSA) level, Gleason score, and T-stage. After risk group determination, the treatment volume and dose are defined and androgen deprivation therapy is prescribed, if appropriate. Traditionally, imaging has played only a minor role in T-staging due to the low diagnostic accuracy of conventional imaging strategies such as transrectal ultrasound, computed tomography, and morphologic magnetic resonance imaging(MRI). As a result, a notable percentage of tumours are understaged, leading to inappropriate and imprecise EBRT. The development of multiparametric MRI(mp MRI), an imaging technique that combines morphologic studies with functional diffusion-weighted sequences and dynamic contrastenhanced imaging, has revolutionized the diagnosis and management of PCa. As a result, mpM RI is now used in staging PCa prior to EBRT, with possible implications for both risk group classification and treatment decisionmaking for EBRT. mpM RI is also being used in salvageradiotherapy(SRT), the treatment of choice for patients who develop biochemical recurrence after radical prostatectomy. In the clinical context of biochemical relapse, it is essential to accurately determine the site of recurrence-pelvic(local, nodal, or bone) or distant-in order to select the optimal therapeutic management approach. Studies have demonstrated the value of mpM RI in detecting local recurrences-even in patients with low PSA levels(0.3-0.5 ng/m L)-and in diagnosing bone and nodal metastasis. The main objective of this review is to update the role of mpM RI prior to radical EBRT or SRT. We also consider future directions for the use and development of MRI in the field of radiation oncology.

关键词： Prostate cancer Staging Radical radiotherapy Multiparametric magnetic resonance imaging Biochemical failure Radical prostatectomy Salvage radiotherapy

The importance of post-COVID condition phenotypes characterization to decipher the mechanisms underlying this post-viral syndrome

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World Journal of Pediatrics 2024年第6期20卷 633-634页

作者： Jon Izquierdo-Pujol sara Moron-Lopez IrsiCaixa and Institute for Health Science Research Germans Trias i Pujol(IGTP) Can Ruti CampusBadalonaSpain Biomedicine doctoral programme Faculty of BiologyUniversity of BarcelonaBarcelonaSpain CIBERINFEC MadridSpain

The coronavirus disease-19(COVID-19)outbreak,caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),was declared a global pandemic in March *** has affected over 700 million people worldwide and resulted in almost 7 million deaths,equating to a 1%mortality *** present,the majority of COVID-19 cases are either asymptomatic or mild,typically resolving within two ***,between 1%and 10%of COVID-19 survivors do not fully recover and experience a post-viral syndrome referred to as"long COVID","post-acute COVID-19 syndrome"(PASC),or"post-COVID condition"(PCC).This post-viral syndrome affects both adult and pediatric ***,most of the studies published to date evaluate the adult population,leaving a gap in our understanding of its impact on children and adolescents.

关键词： acute mortality respiratory

Use of technology and social media in dementia care:Current and future directions

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World Journal of Psychiatry 2021年第4期11卷 109-123页

作者： sara Shu Benjamin KP Woo College of Osteopathic Medicine of the Pacific Western University of Health SciencesPomonaCA 91766United States Department of Psychiatry and Biobehavioral Sciences University of CaliforniaLos Angeles(UCLA)Medical CenterSylmarCA 91104United States

As the population across the globe continues to dramatically increase,the prevalence of cognitive impairment and dementia will inevitably increase as well,placing increasing burden on families and health care *** advancements over the past decade provide potential benefit in not only relieving caregiver burden of caring for a loved one with dementia,but also enables individuals with dementia to age in *** devices have served to improve functioning,tracking and ***,smartphones,tablets and the ubiquitous world wide web have facilitated the dissemination of health information to previously hard to reach populations largely through use of various social media *** this review,we discuss the current and future uses of technology via devices and social media to promote healthy aging in individuals with dementia,and also limitations and challenges to consider in the future.

关键词： Dementia Technology Gerotechnology Social media Geriatrics Wearable technology Health promotion Home health Monitoring

Dermic-derived fibroblasts for the study of amyotrophic lateral sclerosis

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Neural Regeneration Research 2020年第11期15卷 2043-2044页

作者： Javier Riancho sara Arozamena Adolfo Lopez de Munain Service of Neurology Hospital Sierrallana-IDIVALTorrelavegaSpain Department of Medicine and Psychiatry University of CantabriaSantanderSpain Centro de Investigacion en Red de Enfermedades Neurodegenerativas Instituto Carlos IIIMadridSpain Neurosciences Area Biodonostia Research InstituteService of NeurologyHospital Universitario DonostiaDepartment of NeurosciencesSchool of Medicine and NurseryUniversity of the Basque CountrySan SebastianSpain

Among neurodegenerative diseases,amyotrophic lateral sclerosis(ALS)is the most frequent one involving motor neurons(MNs).ALS incidence varies throughout the world ranging from 0.7 to 4 cases per 100,000 habitants and year(Riancho et al.,2016).This disease,which currently lacks an effective therapy,is characterized by a variable combination of upper and lower MN degeneration,leading to progressive muscle wasting which usually results in a terminal respiratory failure within 3 years after symptom onset(Zufiria et al.,2016).A small proportion of ALS cases show familial *** are related to mutations in specific causative genes(Cr9ORF72,TARDBP,FUS,SOD1 and others)which directly determine disease onset in *** contrast,more than 90 percent of cases are considered to be sporadic,in which generally unknown environmental and internal factors interact with genetic predisposing factors finally leading to disease(Riancho et al.,2018).From a histopathological point of view,ALS is characterized by MN damage and *** from ALS sporadic and most of familial patients exhibit prominent transactive response DNA-binding protein 43(TDP-43)cytoplasmic aggregates which are considered as the“pathological hallmark”of the disease,excepting those related to SOD1 and FUS mutations(Zufiria et al.,2016).TDP-43 is a DNA/RNA binding protein encoded by the TARDBP gene that controls the expression of many different genes.

关键词： al. amyotrophic degeneration