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Integrative Zoology 2024年第3期19卷 417-423页

作者： João Pedro Rueda FURLAN Micaela santana RAMOS Fábio Parra SELLERA Irys Hany Lima GONZALEZ Patrícia Locosque RAMOS Eliana Guedes STEHLING Department of Clinical Analyses Toxicology and Food ScienceSchool of Pharmaceutical Sciences of Ribeirão PretoUniversity of São PauloRibeirão PretoBrazil Department of Internal Medicine School of Veterinary Medicine and Animal ScienceUniversity of São PauloSão PauloBrazil School of Veterinary Medicine Metropolitan University of SantosSantosBrazil Coordination of Wild Fauna Secretary of EnvironmentInfrastructure and LogisticsSão PauloBrazil

Antimicrobial resistance(AMR)is a growing phenomenon that poses a major public health challenge worldwide(Dhingra et al.2020;Antimicrobial Resistance Collaborators 2022).The selective pressure exerted in clinical settings has contributed to the longlasting successful dissemination of multidrug-resistant(MDR)Gram-negative bacteria in these environments(Chia et al.2020).

关键词： multidrug clinical

Liver transplantation as an alternative for the treatment of perihilar cholangiocarcinoma: A critical review

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 139-145页

作者： Wellington Andraus Francisco Tustumi Alexandre Chagas santana Rafael Soares Nunes Pinheiro Daniel Reis Waisberg Liliana Ducatti Lopes Rubens Macedo Arantes Vinicius Rocha Santos Rodrigo Bronze de Martino Luiz Augusto Carneiro D’Albuquerque Department of Gastroenterology Transplantation UnitUniversidade de São PauloSão PauloBrazil

Background:Perihilar cholangiocarcinoma(phCCC)is a dismal *** is no consensus regard-ing the best treatment for patients with unresectable *** present review aimed to gather the current pieces of evidence for liver transplantation and liver resection as a treatment for phCCC and to build better guidance for clinical *** sources:The search was conducted in PubMed,Embase,Cochrane,and *** related references were searched *** criteria were:reports in English or Portuguese literature that a)patients with confirmed diagnosis of phCCC;b)patients treated with a curative intent;c)patients with the outcomes of liver resection and liver *** reports,reviews,letters,editorials,conference abstracts and papers with full-text unavailability were excluded from the ***:Most of the current literature is based on observational retrospective studies with low grades of *** resection has better long-term outcomes than systemic chemotherapy or palliation ther-apy and liver transplantation is a good alternative for selected patients with unresectable *** candidates for resection or transplantation should be medically fit and free of intrahepatic or extrahep-atic *** a general rule,patients presenting with a tumor having a longitudinal size>3 cm or extending below the cystic duct,lymph node disease,confirmed extrahepatic dissemination;intraoper-atively diagnosed metastatic disease;a history of other malignancies within the last five years,and did not complete chemoradiation regimen and were medically unfit should not be considered for *** of these criteria should be individually *** transplantation or resection should only be considered in highly experienced hepatobiliary centers,and any decision-making must be based on a multidisciplinary ***:phCCC is a complex condition with high *** therapies,including hepatec-tomy and liv

关键词： Liver transplantation Cholangiocarcinoma Liver neoplasms

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Nutritional Screening Tools in Institutionalized People: A Case Study of Using Nutritional Risk Screening (NRS 2002) and Mini Nutritional Assessment (MNA)

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Food and Nutrition Sciences 2024年第7期15卷 565-575页

作者： Ana Cláudia Araújo santana Daiane Costa dos Santos Mariana Buranelo Egea Campus Rio Verde Goiano Federal Institute of Education Science and Technology Rio Verde Brazil Centro Universitrio UniBRAS de Rio Verde Rio Verde Brazil

Nutritional status expresses the physiological and nutritional needs to maintain the composition and adequate functioning of the organism. NRS 2002 and MNA protocols were applied to short-term institutionalized patients in Rio Verde (Brazil). Older adults and people with special needs of all ages, both sexes, regardless of possible pathology they may have, except if it causes contagion, were included, patients duly authorized by the person responsible for the institution and who were able to undergo evaluation. Thirty-eight patients from the institution were evaluated, of which ten were excluded from the research according to pre-established criteria. More than 50% of participants were male, with an overall average age of 63.43 years. The characteristics related to nutritional status by NRS 2002 and MNA showed that the risk of malnutrition and its absence are associated with a wide age range. The MNA presents a more nuanced nutritional risk classification, showing that even 61% of the 96% of participants who would be out of nutrition risk, according to the NRS 2002, are “at risk of malnutrition”. Applying the MNA can demonstrate more conservative results than the NRS 2002.

关键词： Nursing Home Elderly Nutritional Risk Overweight

Evolutionary fingerprint, phylogenetic and forest structure of tropical montane Atlantic cloud forests along an elevation gradient

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Journal of Mountain Science 2024年第4期21卷 1259-1271页

作者： Ravi Fernandes MARIANO Vanessa Leite REZENDE Cléber Rodrigo de SOUZA Patrícia Vieira POMPEU Rubens Manoel dos SANTOS Carolina Njaime MENDES Aloysio Souza de MOURA Felipe santana MACHADO Warley Augusto Caldas CARVALHO Marco Aurélio Leite FONTES Department of Forest Sciences Federal University of LavrasLavras 37200-900Brazil 2Environmental Defence Association of Minas Gerais Belo Horizonte 30360-110Brazil Department of Ecology and Conservation Federal University of LavrasLavras 37200-900Brazil Department of Forest Sciences State University of Mato Grosso do SulAquidauana 79200-000Brazil Agência Zetta Federal University of LavrasLavras 37200-900Brazil. Department of Natural Sciences Federal University of São João del-ReiSão João del-Rei 36307-352Brazil.

Environmental conditions can change markedly over geographical distances along elevation gradients,making them natural laboratories to study the processes that structure *** work aimed to assess the influences of elevation on Tropical Montane Cloud Forest plant communities in the Brazilian Atlantic Forest,a historically neglected *** evaluated the phylogenetic structure,forest structure(tree basal area and tree density)and species richness along an elevation gradient,as well as the evolutionary fingerprints of elevation-success on phylogenetic lineages from the tree *** do so,we assessed nine communities along an elevation gradient from 1210 to 2310 m *** large elevation *** relationships between elevation and phylogenetic structure,forest structure and species richness were investigated through Linear *** occurrence of evolutionary fingerprint on phylogenetic lineages was investigated by quantifying the extent of phylogenetic signal of elevation-success using a genus-level molecular *** results showed decreased species richness at higher elevations and independence between forest structure,phylogenetic structure and *** also verified that there is a phylogenetic signal associated with elevation-success by *** concluded that the elevation is associated with species richness and the occurrence of phylogenetic lineages in the tree communities evaluated in Mantiqueira *** the other hand,elevation is not associated with forest structure or phylogenetic ***,closely related taxa tend to have their higher ecological success in similar ***,we highlight the fragility of the tropical montane cloud forests in the Mantiqueira Range in face of environmental changes(*** warming)due to the occurrence of exclusive phylogenetic lineages evolutionarily adapted to environmental conditions(*** temperature)associated with each elevation range.

关键词： Atlantic Forest Cloud forest Conservation Community ecology Montane forests Phylogenetic diversity Phylogenetic signal

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气候紧急状态下遗产地保护数字工作流程的机遇与挑战

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中国文化遗产 2024年第1期119卷 50-55页

作者：郑宇马里奥·桑塔纳·坤泰洛卡尔顿大学卡尔顿沉浸式媒体工作室

本文深入探讨了数字工作流程为遗产地应对日益严重的气候变化影响所带来的机遇和挑战，以及需要采取更多样化的方法来帮助确定适应气候变化的优先事项，将遗产保护视为可持续发展和减缓气候变化的驱动力。特别提出使用数字技术来记录易... 详细信息

本文深入探讨了数字工作流程为遗产地应对日益严重的气候变化影响所带来的机遇和挑战，以及需要采取更多样化的方法来帮助确定适应气候变化的优先事项，将遗产保护视为可持续发展和减缓气候变化的驱动力。特别提出使用数字技术来记录易受气候变化现象影响的遗产地的必要性，这些遗产地由于缺乏世界范围的重视和传统遗产保护框架的认可而未被研究。

关键词：数字技术遗产记录有计划的保护遗产地保护气候行动气候紧急状态

Automatic detection of Acacia longifolia invasive species based on UAV-acquired aerial imagery

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Information Processing in Agriculture 2022年第2期9卷 276-287页

作者： Carolina Goncalves Pedro santana Tomas Brandao Magno Guedes ISCTE-Instituto Universitario de Lisboa Portugal Instituto de Telecomunicacoes LisboaPortugal Information Sciences and Technologies and Architecture Research Center(ISTAR-IUL) LisboaPortugal IntRoSys SA Portugal

The Acacia longifolia species is known for its rapid growth and dissemination,causing loss of biodiversity in the affected *** order to avoid the uncontrolled spread of this species,it is important to effectively monitor its distribution on the agroforestry *** this purpose,this paper proposes the use of Convolutional Neural Networks(CNN)for the detection of Acacia longifolia,from images acquired by an unmanned aerial *** models based on the same CNN architecture were *** classifies image patches into one of nine possible classes,which are later converted into a binary model;this model presented an accuracy of 98:6%and 98:5%in the validation and training sets,*** second model was trained directly for binary classification and showed an accuracy of 98:8%and 98:7%for the validation and test sets,*** results show that the use of multiple classes,useful to provide the aerial vehicle with richer semantic information regarding the environment,does not hamper the accuracy of Acacia longifolia detection in the classifier’s primary *** presented system also includes a method for increasing classification’s accuracy by consulting an expert to review the model’s predictions on an automatically selected sub-set of the samples.

关键词： Pattern recognition Convolutional neural networks Invasive plants Acacia longifolia

The Top 100 Twitter Influencers in Infectious Diseases

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Infectious Microbes & Diseases 2023年第1期5卷 36-40页

作者： Marcela Araujo de Oliveira santana Saira Butt Department of Medicine Federal University of UberlândiaUberlândiaBrazil Department of Infectious Disease Indiana University School of MedicineIndianapolisUSA

Healthcare professionals in infectious diseases have been using Twitter to disseminate knowledge and interact with other *** study aimed to identify and characterize the top 100 Twitter influencers in infectious diseases and to analyze the correlation between Twitter and academic *** Right Relevance Application Programming Interface was used to search for the term“infectious diseases,”producing a Twitter topic score for the top 100 infectious disease *** influencers'Hirsch index(h-index)was compared with their Twitter topic score for a possible *** identified that 46%of the infectious disease influencers were physicians.A correlation between the Twitter topic score of the infectious disease influencers and their h-index was not identified(r=0.123,P=0.22).The study also provides a list of the infectious disease influencers for those who have an interest in engaging and interacting with them on Twitter.

关键词： infectious diseases medical education social media

Thiopurines are an independent risk factor for active tuberculosis in inflammatory bowel disease patients

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World Journal of Gastroenterology 2023年第9期29卷 1536-1538页

作者： Flora Maria Lorenzo Fortes Raquel Rocha Genoile Oliveira santana Ciências da Vida Universidade do Estado da BahiaSalvador 41150000Brazil Programa de Pós-Graduação em Medicina e Saúde Universidade Federal da BahiaSalvador 40110060Brazil Ciência da Nutrição Universidade Federal da BahiaSalvador 40110160Brazil

The use of thiopurines is an independent risk factor for active tuberculosis in patients with inflammatory bowel disease.

关键词： Tuberculosis Inflammatory bowel disease Thiopurines Therapy Risk

西班牙重症监护护士对岗位胜任力和培训需求认知的调查研究

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International Journal of Nursing Sciences 2022年第3期9卷 350-356,I0004页

作者： Yeray Gabriel santana-Padilla María Desamparados Bernat-Adell Luciano santana-Cabrera Complejo Hospitalario Universitario Insular Materno Infantil Las Palmas de Gran CanariaCanary IslandsSpain Department of Nursing University of Jaume ICastellonValencian CommunitySpain

目的关于重症监护护士实施安全优质护理所需能力已有多项研究。为进行有效的教育培训,应研究护士对培训的认知情况。本研究旨在评估西班牙重症监护护士对其岗位胜任力和培训重要性的认知。方法在西班牙全国范围内进行多中心、横断面、... 详细信息

目的关于重症监护护士实施安全优质护理所需能力已有多项研究。为进行有效的教育培训,应研究护士对培训的认知情况。本研究旨在评估西班牙重症监护护士对其岗位胜任力和培训重要性的认知。方法在西班牙全国范围内进行多中心、横断面、描述性调查研究。共有85个ICU参与此项研究。调查问卷采用德尔菲法编制,共66个项目,项目评分采用李克特10级计分法。研究得到16个伦理委员会审批同意。结果研究调查了568名西班牙护士。在评估不同项目的培训需求时,学术水平、性别、所在医院类型及专业工作经验不同的护士得分存在差异,不同组别之间问卷总分差异均有统计学意义(P<0.05)。被调查的护士普遍认为,在开始进入ICU工作之前,先行培训并具备其他护理工作经验非常必要。结论实施适合重症监护护士的培训计划有益于护士个人及卫生系统。护士在整个职业周期的不同阶段对培训需求有不同的评估。专业培训应针对重症监护实际工作中的各项技能要求,并适应护士不同专业阶段的需求。

关键词：基于能力的教育重症病人医疗危重症护理卫生人力资源培训护理教育人员开发

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Time-dependent impact of a high-fat diet on the intestinal barrier of male mice

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World Journal of Methodology 2024年第1期14卷 114-123页

作者： Carolline Santos Miranda Daiana Araujo santana-Oliveira Isabela Lopes Vasques-Monteiro Nathan Soares Dantas-Miranda Jade Sancha de Oliveira Glauser Flavia Maria Silva-Veiga Vanessa Souza-Mello Department of Anatomy Rio de Janeiro State UniversityRio de Janeiro 20551030Brazil

BACKGROUND Excessive saturated fat intake compromises the integrity of the intestinal mucosa,leading to low-grade inflammation,impaired mucosal integrity,and increased intestinal permeability,resulting in the migration of lipopolysaccharide(LPS)to other *** To evaluate the chronic effects(at 10 and 16 wk)of a high-fat diet(HFD)(with 50%energy as fat)on the phylogenetic gut microbiota distribution and intestinal barrier structure and protection in C57BL/6 *** Forty adult male mice were divided into four nutritional groups,where the letters refer to the type of diet(control and HFD or HF)and the numbers refer to the period(in weeks)of diet administration:Control diet for 10 wk,HFD for 10 wk,control diet for 16 wk,and HFD for 16 *** sacrifice,biochemical,molecular,and stereological analyses were *** The HF groups were overweight,had gut dysbiosis,had a progressive decrease in occludin immunostaining,and had increased LPS *** progression reduced the number of goblet cells per large intestine area and Mucin2 expression in the HF16 group,consistent with a completely disarranged intestinal ultrastructure after 16 wk of HFD *** Chronic HFD intake causes overweight,gut dysbiosis,and morphological and functional alterations of the intestinal barrier after 10 or 16 ***-dependent reductions in goblet cell numerical density and mucus production have emerged as targets for countering obesity-driven intestinal damage.

关键词： High-fat diet Intestine Ultrastructure Goblet cells Gut microbiota