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Pleomorphic Adenoma of the Salivary Glands: Two Atypical Locations

International Journal of Otolaryngology and Head & Neck Surgery 2024年第3期13卷 251-257页

作者： Sidibé Youssouf Diarra Abraham Samaké Djibril sanogo boubacar Traoré Abdoul Moumine Diarra Kassim Coulibaly Bourama Diakité Youssouf Keita Mohamed Amadou Department of ENT and Head and Neck Surgery Mother-Child University Hospital “ Le Luxembourg&#8221 Bamako Mali Faculty of Medicine and Odontostomatology Bamako Mali Department of ENT and Head and Neck Surgery The Mali-Gavardo Hospital Bamako Mali Ministry of Higher Education and Scientific Research Bamako Mali ENT and Head and Neck Surgery Department of the Commune V Reference Health Center (CSRef CV) Bamako Mali Department of ENT and Head and Neck Surgery at CHU Gabriel Touré Bamako Mali Department of Anatomy and Pathological Cytology Gabriel Tour&#233 University Hospital Center Bamko Mali Department of Oral Surgery Sikasso Regional Hospital Sikasso Mali

Pleomorphic adenoma is the most common tumor of the salivary glands, accounting for approximately 50% of salivary gland lesions. It develops mainly in the salivary glands: parotid (80%), submaxillary (10%), sublingual (1%) and in the accessory oral-pharyngeal glands (9%). The aim of this work was to report 2 cases of pleomorphic adenoma of atypical location and then to discuss the difficulties linked to its diagnostic and therapeutic management in the Malian context. They were a 40-year-old man and a 72-year-old woman. They were admitted to the ENT department of the “Luxembourg Mere-infant” hospital for oropharyngeal swelling for the first and swelling of the palate for the second. The clinical expression was a swelling in both cases, of a hard, mobile consistency with healthy mucosa on their surface. The remainder of the physical examination was unremarkable. The diagnosis of a tumor of the oropharynx and palate was made following clinical radiological examinations. The histopathological examination of the surgical specimen made it possible to make the diagnosis of pleomorphic adenoma of the palate and the left palatine tonsil. The follow-up surgery was straightforward, with a favorable outcome. Pleomorphic adenomas are relatively rare benign tumors of the accessory salivary glands;their clinical expression remains swelling. Therapeutic management is surgery and the diagnosis is confirmed by histopathological examination.

关键词： Pleomorphic Adenoma Palate Tonsil Mali

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Surgical Management of Larges Goiters in the ENT Department of CHU Mother and Child“Luxembourg”

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International Journal of Otolaryngology and Head & Neck Surgery 2019年第4期8卷 139-149页

作者： Youssouf Sidibe Abdoul Wahab Haidara Djibril Samake Abdoulaye Kante Siaka Soumaoro boubacary Guindo Nagnouma Camara Mamadou Karim Toure Mahmoud Cisse Amadou Djibo Youssouf Djigui Diakite boubacar sanogo Mohamed Amadou Keita ENT and Head and Neck Surgery Department CHU Mother-Child“Luxembourg”BamakoMali ENT and Head and Neck Surgery Department Reference Health Center District VBamakoMali Laboratory of Anatomy of the Faculty of Medicine and Odontostomatology BamakoMali ENT and Head and Neck Surgery Department CHU Gabriel ToureBamakoMali Department of Anesthesia Resuscitation CHU Mother-Child“Luxembourg” BamakoMali Department of Endocrinology Mother-Child University Hospital“Luxembourg”BamakoMali

Objectives: To study the clinical and therapeutic profiles of voluminous goiter. Patients and Methods: We carried out a descriptive and prospective study, relating to a series of 30 cases of voluminous goitre, collected in the Department of Otorhinolaryngology and cervicofacial surgery (ENT and CCF) of the CHU Luxembourg Mother Child of Bamako. It has been spread over a period of 4 years from January 2015 to December 2018. Patients of all ages operated for large goitre at the ENT Department of CHU Luxembourg Mother Enfant were included. Results: In 4 years we collected 30 cases of voluminous goitre;during this period we realized 180 thyroidectomies, i.e. frequency of 16.67%. The average age was 51.37 years with an extreme ranging from 38 to 65 years. Females were common in 66.7% with a sex ratio of 0.50. The long duration of evolution has been 40 years. The sign of compression was found in 85.7%. The physical examination found a mobile swelling, hard and painless in all patients with normal endolaryngeal examination;there was no cervical lymphadenopathy. The lower dipping pole was found in 5 cases on CT. All our patients were euthyroid. The classification of TIRADS 2 was found in 80.0% of cases. Total thyroidectomy was frequent with 50.0% of cases. The average weight of the operative specimen was 586.67 g with extremes ranging from 500 g to 800 g. The size of the operative piece of 14 cm was the longest. Injury of internal jugular vein was found in 26.7% of cases. Colloid adenoma of the thyroid was found in 100% of cases, postoperative complications of the type of hematoma of the lodge in 3.3% of cases, the release of the operative wound in 10% of cases local superinfection in 7.1%. Signs of hypothyroidism were common with 50.0%. Postoperative nasofibroscopy found good vocal fold mobility in all patients. Conclusion: The large goiters have become rare because of the early management of thyroid nodule. Its management must allow the prevention of recurrent and parathy

关键词： Thyroid Large Goiter Thyroidectomy

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Surgical Reports of the Inferior Laryngeal Nerve and the Inferior Thyroid Artery in General Surgery and in ENT

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Forensic Medicine and Anatomy Research 2019年第1期7卷 24-30页

作者： Youssouf Sidibé Abdoulaye Kanté Bréhima Bengaly Siaka Diallo Mariam Daou Drissa Ouattara Babou Ba Bréhima Coulibaly Birama Togola Drissa Traoré Abdoul Wahab Haidara boubacar sanogo Nouhoum Ongoï ba ENT and Head and Neck Surgery Department CHU “Mother-Child” The Luxembourg Bamako Mali Service of Surgery B. CHU Point G Bamako Mali Laboratory of Anatomy of the Faculty of Medicine and Odontostomatology Bamako Mali Service of Neurology CHU Gabriel Touré Bamako Mali

Aim: The purpose of this study was to determine the frequency of the hurts of the inferior laryngeal nerve, according to its anatomical reports with the inferior thyroid artery during the thyroid surgery. Methodology: We realized a forward-looking and retrospective study from January, 1979 till December, 2017 in the service of surgery “B” to the University hospital of the Point G of Bamako and in the service of ENT and cervico-facial surgery of the Teaching Hospital “Mother-Child”, the Luxembourg of Bamako (Mali). All the patients operated in both services for mild goiters were retained. Cancers and other thyroid pathologies were not included. The diagnosis of mild goiter was paused by the histological examination realized on all the surgical specimens. Results: On 2109 dissections of the inferior laryngeal nerve realized during the surgical operations on the thyroid, the frequency of lesion of the inferior laryngeal nerve was 1.09% (20 cases) when it passed dorsally with regard to the inferior thyroid artery (1837 cases) and when 4.04%, it was transvascular or prevascular (272 cases). Conclusion: The prevascular route or transvascular of the inferior laryngeal nerve favors its lesion per operating.

关键词： Anatomy Inferior Laryngeal Nerve Recurring Nerve Thyroid Surgery Goiter

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Tonsillitis and Their Complications: Epidemiological, Clinical and Therapeutic Profiles

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International Journal of Otolaryngology and Head & Neck Surgery 2019年第3期8卷 98-105页

作者： Abdoul Wahab Haidara Youssouf Sidibé Djibril Samaké Amady Coulibaly Mamadou Karim Touré Bréhima Bolonpé Coulibaly Siaka Soumaoro boubacary Guindo Kassim Diarra Kalifa Coulibaly boubacar sanogo Mohamed Kéï ta Alhousseini Ag Mohamed ENT and Head and Neck Surgery Department CHU Mother-Child “Luxembourg” Bamako Mali ENT and Head and Neck Surgery Department Reference Health Center Bamako Mali Department of Stomatology and Maxillofacial Surgery CHU-CNOS Bamako Mali Department of Anesthesia Resuscitation CHU Mother-Child “Luxembourg” Bamako Mali ENT and Head and Neck Surgery Department CHU Gabriel Toure Bamako Mali

Tonsillitis or angina, is considered as an inflammation of the palatine tonsils most often of infectious origin. It can be acute or chronic. The germs in question are mostly viruses and bacteria. Objectives: The objective of this work was to study the epidemiological and therapeutic profile of tonsillitis and their complications in the ENT Department and Head and Neck Surgery of the Mother-Child University Hospital in Luxembourg. Patients and Methods: This is a prospective study over a 12-month period from January 2018 to December 2018, including all patients who presented with tonsillitis and/or their complications. Results: Three hundred and fifteen (315) patients were collected during this period. The average age in our study was 14.25 years with extremes ranging from 2 years to 61 years. The sex ratio was 0.65 in favor of the female sex. During this period we recorded 80.95% of cases of uncomplicated tonsillitis including 60.50% for acute tonsillitis, 24.5% for chronic tonsillitis 5% for adenoid tonsillitis and 19.05% for complications. Complications included peritonsillar phlegmon 42.22%, heart disease 33.33%, cervical cellulitis 8.89%, adeno-phlegmon 6.67%, para-pharyngeal abscess 4.44%, and sepsis 4.44%. The exclusive medical treatment was performed in 44.31%. Surgical treatment (drainage incision and tonsillectomy) was performed in 55.69%. Conclusion: Tonsillitis and its complications represent an important pathology in ENT. Feynophagy febrile is the pair-origin symptom that can lead to the diagnosis. The prevention of complications is the guarantor of the reduction of its morbidity. We recommend that in the absence of RDT (Rapid Diagnostic Test), it is necessary to systematize antibiotic therapy to prevent serious complications.

关键词： Tonsillitis Complication Mali

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Giant Cervical Kystic Lymphangioma in Children: Surgical Management of a Case

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International Journal of Otolaryngology and Head & Neck Surgery 2019年第1期8卷 1-6页

作者： Youssouf Sidibé Abdoulaye Kanté Amady Coulibaly Rokia Koné Mamadou Koné Fatoumata Léonie Franç ois Diakité Drissa Ouattara Abdoul Wahab Haidara boubacar sanogo Sidiki Dao N’faly Konate Kadiatou Singaré Doumbia Samba Karim Timbo Mohamed Keita Alhousseini Ag Mohamed ENT and Head and Neck Surgery Department CHU Mother-Child “Luxembourg” Bamako Mali ENT and Head and Neck Surgery Department CHU Gabriel Touré Bamako Mali Faculty of Medicine and Odontostomatology Bamako Mali Service of Surgery “B” CHU Point G Bamako Mali Department of Stomatology and Maxillofacial Surgery CHU-CNOS Bamako Mali Dermatology Department of the National Center for Disease Control Support (CNAM) Bamako Mali Service of Paediatrics CHU Gabriel Touré Bamako Mali

Introduction: Cervical cystic lymphangiomas are rare benign dysembryoplastic tumors of lymphatic origin. Its severity in the child is due on one hand to their fast evolution and the compression of the way aerodigestive and on the other hand, by the classical difficulty of their excision. The purpose of this work was to report a case of giant cervical cystic lymphangioma in a child to discuss the difficulties associated with its management in our context. Observation: This was a 3-year-old female child who was admitted to the ENT department of CHU “Luxembourg” for right lateral cervical swelling. The clinical examination had noted a large anterior-latero cervical swelling of soft, renitent, painless palpation, movable in relation to the superficial and deep plane, measuring about 20 cm × 17 cm, the skin was healthy. It wasn’t particularity to the rest of the physical examination. The diagnosis of giant cervical cystic lymphangioma was discussed. Thorough excision of the swelling by right lateral cervicotomy was performed. Anatomopathological examination of the operative specimen confirmed the diagnosis. The postoperative course was simple and the evolution was favorable. Conclusion: Cervical cystic lymphangiomas are rare. Their management involves surgery, with short and long-term post-operative outcomes are often excellent.

关键词： Kystic Lymphangioma Cervical Child Bamako

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Place of Otorhinolaryngological (ENT) Diseases in a 2<i>nd</i>Level Health Center: Case of the of Commune V (CSRéf CV) Reference Health Center of the District of Bamako

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International Journal of Otolaryngology and Head & Neck Surgery 2019年第3期8卷 91-97页

作者： Djibril Samaké Youssouf Sidibé Sinaly Thiocary Fatogoma Issa Koné Youma Mamadou Maï ga Fatoumata Konaté Yatemelou Dara Kadidiatou Singaré Abdoul Wahab Haidara Adama Dembele Djeneba Sacko Mamadou Traoré boubacar sanogo Samba Karim Timbo Mohamed Amadou Kéï ta Alhousseini Ag Mohamed ENT and Head and Neck Surgery Department Reference Health Center Bamako Mali ENT and Head and Neck Surgery Department CHU Mother-Child “Luxembourg” Bamako Mali ENT and Head and Neck Surgery Department CHU Gabriel Touré Bamako Mali Mother and Child Health Research and Training Unit Reference Health Center Bamako Mali Pediatric Service Reference Health Center Bamako Mali

Objective: Provide the place of ENT diseases at the Reference Health Center of the Commune V of Bamako. Materials and Method: A cross-sectional study using ENT medical assessment was carried out from January 2017 to December 2017 at the Reference Health Center of Commune V of Bamako’s District. Results: 1911 patients were included and that number represented 15.46% of all non-obstetrics medical consultations in the health center. The sex ratio was 0.83 for women (54.7%). The average age was 22 years old. Otologic diseases were 66.4% of the cases followed by nasal sinus cases (16.6%). Infectious and inflammatory diseases were 74.1% and were the main diagnosed diseases. The difficulties were mainly from technical platform. Conclusion: The diversity of these pathologies required a strong development or reinforcement of human and material resources capacities in of these structures for proximity care management.

关键词： ENT Disease Care Reference Health Center

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Morbidity and Mortality of Newborns in a Context of Limited Resources in Tombouctou, Mali

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Open Journal of Pediatrics 2024年第5期14卷 841-850页

作者： Kassogué Djibril Cissouma Assétou Kassogué Abdoulaye Boré boubacar Sogoba Robert Diallo Zoumana Maiga Talfi Dolo Akoro Sogoba Seydou Touré Lahaou Maiga Mariam Samaké Alou Mariko Souleymane Ongoiba Oumar sanogo Oumar Traoré Bassirima Paediatrics Department Timbuktu Hospital Timbuktu Mali Paediatrics Department Sikasso Hospital Sikasso Mali Paediatrics Department Nianankoro Fomba Hospital Ségou Mali Department of Obstetrics and Gynaecology CHU du Point G Bamako Mali Department of Paediatrics Commune VI District Hospital Bamako Mali

Introduction: Worldwide, 2.3 million children died in the first 20 days after birth in 2022, according to the WHO. In Mali, according to the sixth Demographic and Health Survey, the neonatal mortality rate was estimated at 33% live births in 2018. The Timbuktu region had the highest neonatal mortality rate in the country with 44%. The objective of this work was to study the causes of neonatal morbidity and mortality and related factors in the paediatrics department of Timbuktu hospital. Materials and method : This was a descriptive, cross-sectional study conducted from 1 January to 31 December 2023 in the neonatology unit of the paediatrics department of Timbuktu hospital, including all newborns admitted to hospital. Results : Our study took place over 12 months, during which 618 admissions were made to the paediatric ward, including 244 newborns, i.e. 39.48%. The majority of newborns (86.5%) were admitted in the first week of life. The mean age was 3 days, with a sex ratio of 1.1 for males. Weight under 2500 g was 54.1% for an average weight of 2372 g. The main mode of admission was transfer from the hospital maternity unit (62%). The main reasons for admission were acute foetal distress (27.9%) and prematurity (26.2%). The average age of the mothers was 24, with extremes of 15 and 49. The mothers were housewives (87.3%), uneducated and primiparous (59% and 36.5% respectively); only 40.2% had made more than 3 antenatal care visits. Newborns born by vaginal delivery accounted for 80.7% and those born by caesarean section for 19.3%. The risk of infection was present in 52.5% of cases. The three leading causes of hospitalisation were birth asphyxia (40.2%), neonatal infection (32.4%) and prematurity (25%). The mortality rate was 21.7%. The main causes of death were prematurity (39.6%), birth asphyxia (32.1%) and neonatal infection (24.5%). Conclusion : Neonatal morbidity and mortality remain a concern in Timbuktu. Despite the unfavourable security situation, morbidity

关键词： Morbidity Mortality Newborns Timbuktu

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Liposarcoma Retro-Peritoneal in the General Surgery Department of the Hospital of the District of the Commune IV

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Surgical Science 2024年第7期15卷 430-437页

作者： Moussa Samaké Souleymane Bingué Dembelé Yely Dianessy Abdou Guiré Dorcas Laurel Sodjiné Yede Youssouf Boiré Mahamane Dicko Mantia Sara Nouhoum sanogo Amaguiré Saye Sirama Diarra Brahima Dembele Thierno Nadio Ibrahima Maiga Modibo Diarra Siaka Konaté Birama Cheick Traoré boubacar Diassana Bathio Traoré Amadou Maiga boubacar Yoro Sidibé Adégné Togo General Surgery Department of Bamako District IV Hospital Bamako Mali Anesthesia and Resuscitation Service of the Hospital of the District of the Commune IV of Bamako Bamako Mali Anatomopathology Department of the CHU of Point G Bamako Mali Obstetric Gynecology Department of the Bamako District IV Hospital Bamako Mali Department of Ophthalmology of the Hospital of the District of the Commune IV of Bamako Bamako Mali Imaging Service of the Bamako District IV Hospital Bamako Mali Internal Medicine Department of the District Hospital of Commune IV of Bamako Bamako Mali General Surgery Department Kolondjeba Referral Health Centre Sikasso Mali Gynecology and Obstetrics Department of the San Reference Health Center Segou Mali General Surgery Department of Sikasso Hospital Sikasso Mali General Surgery Department of the Gabriel Tour University Hospital Bamako Mali

Retroperitoneal soft tissue sarcomas in the retroperitoneal/intra-abdominal regions represent 10% - 15% of all cases of soft tissue sarcoma. Liposarcomas, which are the most common histological type, account for 20% - 45% of retroperitoneal/intra-abdominal sarcoma cases, and 20% of liposarcomas cases are primary retroperitoneal liposarcomas. Surgical resection in case of malignancy remains the treatment of choice for liposarcomas, according to the guidelines of most major international companies. Our goal was to improve the management of retroperitoneal liposarcoma. This was a 65-year-old patient, with no medical or surgical history, who was referred to us for abdominal swelling, in whom clinical and paraclinical examination found retroperitoneal liposarcoma stage IV, and the surgical treatment consisted in making a tumor reduction. Conclusion: Retro-peritoneal liposarcoma is an undervalued malignant tumor, and the diagnosis is often late.

关键词： Retroperitoneal Liposarcoma Diagnostic Delay

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Cushing Syndrome Revealing an Adrenocortical Carcinoma

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Open Journal of Pediatrics 2018年第2期8卷 87-93页

作者： Bintou sanogo Senkaye-Lagom Aimée Kissou Zakari Nikiema Makoura Barro Djingri Lankouandé boubacar Nacro Department of Pediatrics University Hospital Center Souro Sanou (CHUSS) Bobo-Dioulasso Burkina Faso Higher Institute of Health Sciences Nazi Boni University (UNB) Bobo-Dioulasso Burkina Faso Medical Imaging Service Bobo-Dioulasso Burkina Faso Department of Internal Medicine Bobo-Dioulasso Burkina Faso

Adrenocortical carcinoma is a malignant tumor of the adrenal gland, very rare in pediatric pathology. Authors presented a pediatric case of adrenocortical carcinoma which showed neurology symptoms at 1st visit and Cushing syndrome secondarily. The patient received a ketoconazole-based treatment. The outcome was fatal before the surgical excision of the tumor, because of delayed diagnosis. Early diagnosis and multidisciplinary management of adrenocortical carcinoma could improve the prognosis in children.

关键词： Cushing Syndrome Adrenocortical Carcinoma Child

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Selection of Cocoa Tree (<i>Theobroma cacao</i>Linn) Endophytic Bacteria Solubilizing Tri-Calcium Phosphate, Isolated from Seedlings Grown on Soils of Six Producing Regions of Côte d’Ivoire

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Advances in Microbiology 2019年第9期9卷 842-852页

作者： Adama Ouattara Klotioloma Coulibaly Ibrahim Konate boubacar Ismael Kebe Abiba sanogo Tidou Abdelkarim Filali-Maltouf UFR Agro-Forestry and Environment Department of Biochemistry and MicrobiologyLaboratory of AgrovalorizationJean Lorougnon Guede UniversityDaloaCote d’Ivoire National Center for Agronomic Research(CNRA) Laboratory of PhytopathologyDivoCote d’Ivoire Faculty of Sciences Laboratory of Microbiology and Molecular BiologyUniversity Mohammed V-AgdalRabatMorocco

Phosphorus (P) is an essential macronutrient for the growth and development of cocoa tree (Theobroma cacao Linn). Most of the soils used for cocoa farming in C?te d’Ivoire are low in phosphorus. But cocoa farmers generally have a widespread reluctance to invest in chemicals fertilizers due to high costs and environmental associated risk. Phosphate Solubilizing Bacteria (PSB) are kwon to play an important role in supply of phosphorous to plants in a sustainable manner in P deficient soils. The aim of this research was to screen the endophytic bacteria of cocoa nurseries able to solubilize tri-calcium phosphate. Seedlings of two varieties of cocoa (P7 and NA32) and seedlings of an all-comer, were grown on eighteen (18) samples soils collected in six producing regions of C?te d’Ivoire. A total of 218 endophytic bacteria were isolated and tested on the Pikovskaya’s agar medium, containing Ca3 (PO4) 2. The colonies with clear zone around the microbial growth were suspected as phosphate solubilizing bacteria. Out of 218 bacteria, 90 (41.28%) showed a clear zone around colonies after 7 days of incubation. The Phosphate Solubilization Index (PSI) ranged from 20% to 200%. Bacterial isolated from the soils of Duékoué locality showed the highest mean index of 137.67%. Five PSB (CEBSP5, CEBSP6, CEBSP7, CEBSP8, and CEBSP9) from Duékoué soils and two PSB (CEBSP12 and CEBSP13) from Soubré soils have a PSI ranged from 150% to 200%. Further study in greenhouse and in field condition will confirm the use of these PSB as biofertilizer to increase the available P content in soils, reduce environmental pollution and promote sustainable agriculture.

关键词： Endophytic Bacteria Theobroma cacao Ti-Calcium Phosphate Solubilization Biofertilizer

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