检索结果-南通市图书馆

作者： sanne post 复旦大学

学位级别：硕士

本文有助于研究特定国家投资者在非洲投资的风险认知差异这一金融研究。在本文中,将对比分别为中国和荷兰的政策性银行和机构进行非洲投资的中国与荷兰投资者的风险认知。现有文献指出,中西方投资者对各种风险的认识不同。然而在中国与... 详细信息

本文有助于研究特定国家投资者在非洲投资的风险认知差异这一金融研究。在本文中,将对比分别为中国和荷兰的政策性银行和机构进行非洲投资的中国与荷兰投资者的风险认知。现有文献指出,中西方投资者对各种风险的认识不同。然而在中国与荷兰投资者在非洲市场的风险认知方面,没有结论性研究。笔者通过调查结果的数据分析,研究了中国与荷兰的金融机构投资者在非洲进行投资时,在风险认知上有何不同。来自四个不同金融机构的18名荷兰投资者和15名中国投资者在利式态度量表上排列了26种风险因素。通过下面的分布拟合法,两个样本均按重要程度排列这些风险因素。结果显示,尽管两个样本的风险认知具有各种相似性,在重要风险的排列上存在本质上的不同。中国投资者认为政治风险,例如冲突、政府的稳定性和官僚素质以及民族信仰矛盾等非常重要。荷兰投资者则认为项目风险、企业管理、金融项目风险以及环境和社会风险很重要。两个样本在风险认知上的相似性有：都认为腐败风险一般重要,环境和社会风险很重要,国家的经济和金融风险不太重要。研究表明,基于对风险认知存在相似性,在非洲市场的合作具有共同基础。

关键词：风险认知中国荷兰外国直接投资非洲

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Alternatives for large-scale production of cultured beef: A review

引用

Journal of Integrative Agriculture 2015年第2期14卷 208-216页

作者： Matilda S M Moritz sanne E L Verbruggen Mark J post Department of Physiology Maastricht UniversityMaastricht 6229 ER The Netherlands Department of Physics Chemistry and Biology Linkping UniversityLinkping SE-581 83 Sweden

Cultured beef is a method where stem cells from skeletal muscle of cows are cultured in vitro to gain edible muscle tissue. For large-scale production of cultured beef, the culture technique needs to become more efficient than today＇s 2-dimensional（2D） standard technique that was used to make the first cultured hamburger. Options for efficient large-scale production of stem cells are to culture cells on microcarriers, either in suspension or in a packed bed bioreactor, or to culture aggregated cells in suspension. We discuss the pros and cons of these systems as well as the possibilities to use the systems for tissue culture. Either of the production systems needs to be optimized to achieve an efficient production of cultured beef. It is anticipated that the optimization of large-scale cell culture as performed for other stem cells can be translated into successful protocols for bovine satellite cells resulting in resource and cost efficient cultured beef.

关键词： cultured beef microcarriers aggregated cells packed bed bioreactor cell culture

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A critical look at the clinical application of Cutometer in the assessment of visco-elasticity of post burn hypertrophic scar

A critical look at the clinical application of Cutometer in ...

引用

中国康复医学会第二届全国康复治疗学术会议

作者： sanne Fong SL Jack Cheng CY

＜正＞This paper aims at studying the use of clastometry in recording the progress of post-burn hypertrophic scar. The reliability of using a skin elastometry （Cutometer SEM 575 ） in the assessment of hypertrophic scar was studied and revealed by Fong, Cheng ＆ Hung （1997）. Reasonable inter- and intra-examiner reliability results were accepted 18 consecutive burn cases were randomly selected and longitudinally studied since December, 1994. Both adults

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

The Effects of Influenza Vaccination on Immune Function in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

引用

International Journal of Clinical Medicine 2012年第6期3卷 544-551页

作者： Ekua Weba Brenu Mieke van Driel Donald R. Staines sanne Kreijkamp-Kaspers Sharni Lee Hardcastle Sonya Maree Marshall-Gradisnik School of Medical Science Griffith Health Institute Griffith University Gold Coast Campus Gold Coast Australia

Immune dysfunction is a hallmark of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). The purpose of this pilot study was to identify the effects of influenza vaccination on immune function in patients with CFS/ME. We included 7 patients meeting the Centre for Disease Control and Prevention criteria (CDC 1994) for ME/CFS and 8 control subjects. Bloods were collected from all participants prior to vaccination with Influvac, a trivalent inactivated influenza vaccine (TIV), 14 and 28 days following vaccination. The immune parameters examined include Natural Killer (NK) phenotypes, NK cytotoxic activity, FOXP3 and Th1/Th2/Th17 related cytokines. Flow cytometric protocols were employed. There was no significant difference in NK phenotypes and Tregs numbers between CFS/ME patients and healthy controls. However, NK activity was significantly decreased at baseline and at 28 days, while at 14 days it significantly increased in the CFS/ME patients compared to the healthy controls. Th1 pro-inflammatory cytokines increased considerably in the CFS/ME patients at 28 days compared to the non-fatigued controls. Only one Th2 cytokine, IL-4, increased in the CFS/ME participants. FOXP3 expressing Tregs only increased significantly at day 28 post vaccination in the CFS/ME patients compared to the healthy controls. Self-rated wellbeing was lower for patients at day 28 while at baseline and day 14 no differences were observed. In this pilot study immunization with influenza vaccine is accompanied by a degree of immune dysregulation in CFS/ME patients compared with controls. While vaccination may protect CFS/ME patients against influenza, it has the ability to increase cytotoxic activity and pro-inflammatory reactions post vaccination. The role of Tregs in promoting a toxic effect at 28 days post-vaccination in our patient group cannot be ruled out. The benefits of influenza vaccine still likely outweigh the risks CFS/ME patients experience following vaccination.

关键词： Chronic Fatigue Syndrome Influenza Vaccination Natural Killer Cells Cytokines

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

抗狂犬病VHH和疫苗用于暴露后处置显著提高小鼠对致死性狂犬病感染的保护作用

引用

中华实验和临床病毒学杂志 2017年第5期31卷 408-408页

作者： sanne Terryn Aurelie Francart Heidi Rommelaere 吕新军唐浏英 National Reference Centre of Rabies Viral Diseases Scientific Institute of Public Health (WIV-ISP) Brussels Belgium. Laboratory of Virology Department of Virology Parasitology and Immunology Faculty of Veterinary Medicine Ghent University Ghent Belgium. Ablynx NV Ghent Belgium.

狂犬病暴露后处置需要在暴露后尽快使用抗狂犬病免疫球蛋白和狂犬病疫苗。由于抗狂犬病免疫球蛋白昂贵且稀缺，可以持续生产的更加廉价的替代品有现实需求。此前，我们研发了针对狂犬病病毒糖蛋白的可以有效中和狂犬病病毒的VHH。

关键词：抗狂犬病狂犬病疫苗暴露后保护作用致死性免疫球蛋白感染小鼠

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

应用弹性测量仪和超声波评价烧伤后增生瘢痕的粘弹性

引用

中华物理医学与康复杂志 2002年第11期24卷 671-674页

作者：方少丽郑振耀香港玛嘉烈医院香港中文大学

目的　研究应用弹性测量仪和超声波测量评价烧伤后增生瘢痕的变化。方法　自 1 995年 1月起 ,长期随访 1 8例随机选择的烧伤患者 (年龄为 1～ 60岁 ) ,应用皮肤弹性测量仪及超声波影像对患者每月测量一次皮肤在负压吸引作用下的最大变形... 详细信息

目的　研究应用弹性测量仪和超声波测量评价烧伤后增生瘢痕的变化。方法　自 1 995年 1月起 ,长期随访 1 8例随机选择的烧伤患者 (年龄为 1～ 60岁 ) ,应用皮肤弹性测量仪及超声波影像对患者每月测量一次皮肤在负压吸引作用下的最大变形度 (R0 )和粘弹性指数 (R8) ,比较增生瘢痕与身体对侧相应部位测量的区别 ,并将检查结果与传统临床分度方法进行比较分析。同时也对皮肤弹性值与临床观察的瘢痕硬度进行相关性分析。结果　烧伤后增生瘢痕的R8>0 .1 93时 ,临床硬度分度也较高 (9%为 0度 ,1 4 %为 1度 ,30 %为 2度 ,46 %为 3度 ,83 %为 4度 )。结论　R8>1 .93被定为预后数值 ,大于该数值者需要密切随访。

关键词：弹性测量仪超声波烧伤增生瘢痕粘弹性临床分度

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Enhanced Gene Expression Following Vaccination in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

引用

International Journal of Clinical Medicine 2013年第3期4卷 165-170页

作者： Ekua W. Brenu Gunn M. Atkinson Mieke L. van Driel sanne Kreijkamp-Kaspers Don R. Staines Sonya M. Marshall-Gradisnik Discipline of General Practice School of Medicine The University of Queensland Brisbane Australia. Faculty of Health Sciences and Medicine Bond University Gold Coast Australia. National Center for Neuroimmu- nology and Emerging Diseases Griffith University Gold Coast Australia. Queensland Health Gold Coast Public Health Unit Gold Coast Australia. School of Medical Science Griffith Health Institute Griffith University Gold Coast Australia.

Vaccines have been shown to cause differential expression of genes and increase antibody titers against antigens. Influenza vaccines may have an effect on unexplained disorders such as Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). Immunological changes have been identified following immunization with trivalent influenza vaccine (TIV). The objective of this pilot study was to examine the consequences of TIV on cytokine and cytotoxic genes in CFS/ME. Peripheral blood mononuclear cells were preferentially isolated from whole blood of 7 CFS/ME patients and 8 controls. Following total RNA extraction and synthesis of cDNA, reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) was used to determine the expression levels of mRNAs for cytotoxic genes (perforin (PRF1), granzyme A (GZMA), granzyme B (GZMB) and cytokine genes. GZMB was significantly increased overall in the CFS/ME patients compared to the controls. GZMA was significantly increased 28 days after vaccination while PRF1 was reduced prevaccination but increased 14 days post-vaccination in the CFS/ME patients. There were no significant changes in cytokine genes pre or post vaccination. Administration of TIV may increase the expression of lytic genes in CFS/ME and this may contribute to the increase in cytotoxic activity we observed in these patients post vaccination.

关键词： Chronic Fatigue Syndrome Perforin Granzymes Cytokines

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：