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Open Journal of Composite Materials 2024年第3期14卷 109-123页

作者： Deepak.Babasaheb Phasage sanjay k. sharma Balram Tripathi Sonia Chahar Srivastava Department of Chemistry JECRC University Jaipur India S. S. Jain Subodh PG College Jaipur India

This study used a Polyindole in combination with TiO2 nanocatalyst as an efficient heterogeneous catalyst to carry out a multi-component Hantzsch reaction involving different aromatic aldehydes with methyl acetoacetate, and aqueous ammonium to create 1,4-dihydropyridine derivatives under solvent free condition at ambient temperature. A broad range of aldehydes and methyl acetoacetates, ranging from heteroaromatic to polyaromatic one, with high level of functional group tolerance can be used to provide the desired products possessing relevant medicinal moiety in high yields. This technology has prospective advantages over current protocols, including the utilization of a cheap, stable, recyclable, and safe catalyst, quick.r reaction times with higher yields and simple product isolation.

关键词： TiO2 Nanocatalyst Green Synthesis Surface Morphology

One-Pot Green Synthesis of 1,4-Dihydropyridine Derivatives Using Polyindole TiO2 Nanocatalyst by Solvent Free Method

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Dengue causing relapse of minimal change disease: A double-edged sword

Open Journal of Composite Materials（复合材料期刊） 2024年第3期 109页

作者： Deepak.Babasaheb Phasage sanjay k. sharma Balram Tripathi Sonia Chahar Srivastava

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Asian Pacific Journal of Tropical Medicine 2024年第5期17卷 237-238页

作者： Sourabh sharma Himanshu Verma sanjay k.lra Department of Nephrology VMMC&Safdarjung HospitalNew DelhiIndia Department of Endocrinology Bharti HospitalKarnalIndia

Dengue virus infection is endemic in India with seasonal *** can lead to lethal consequences with plasma leak.ge and/or bleeding[1,2].Dengue shock.syndrome has high mortality in developing countries lik. *** can cause functional proteinuria and even heavy proteinuria[3-6].Though dengue has been implicated to cause glomerulonephritis[7],to the best of our k.owledge,dengue as a cause of relapse of minimal change disease(MCD)has not been reported.

关键词： relapse mortality bleeding

Numerical modelling of post-failure behaviors of coal specimens

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Journal of Rock.Mechanics and Geotechnical Engineering 2024年第2期16卷 514-531页

作者： Ajeet Yadav Bhask.ra Behera Gauri Shank.r Prasad Singh sanjay k.mar sharma Department of Mining Engineering Indian Institute of Technology(Banaras Hindu University)VaranasiUttar Pradesh221005India

A modelling approach consisting of best-fit relations to estimate the post-yield strength parameters is presented for simulating post-peak.behavior beyond the point of residual strength of coal pillars having different w/h *** model was developed based on back.analysis of the complete stress-strain behavior of specimens belonging to six different Indian coal seams with different w/h ratios of 0.5 *** was found that the simultaneous degradation of the cohesion and friction angle of the Mohr-Coulomb rock.material characterizes the post-peak.strength behavior of the *** resulting expressions are simplistic as they require parameters that can be easily determined using uniaxial and triaxial compression ***,the developed model was validated by simulating the triaxial tests of coal specimens with different sizes under varying confining stresses and comparing its findings with the published test *** study showed that its implementation in the numerical model could reproduce laboratory-observed mechanical response,deformation behavior,and failure mechanism very closely.

关键词： Strain softening Dilatancy Interface Shape effect Residual strength

Machine Learning Techniques Using Deep Instinctive Encoder-Based Feature Extraction for Optimized Breast Cancer Detection

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Computers, Materials & Continua 2024年第2期78卷 2441-2468页

作者： Vaishnawi Priyadarshni sanjay k.mar sharma Mohammad k.alid Imam Rahmani Baijnath k.ushik.Rania Almajalid Department of Computer Science Gautam Buddha UniversityGreater NoidaUttar PradeshIndia College of Computing and Informatics Saudi Electronic UniversityRiyadh11673Saudi Arabia School of Computer Science Shri Vaishno Devi UniversityKatraIndia

Breast cancer(BC)is one of the leading causes of death among women worldwide,as it has emerged as the most commonly diagnosed malignancy in *** detection and effective treatment of BC can help save women’s *** an efficient technology-based detection system can lead to non-destructive and preliminary cancer detection *** paper proposes a comprehensive framework.that can effectively diagnose cancerous cells from benign cells using the Curated Breast Imaging Subset of the Digital Database for Screening Mammography(CBIS-DDSM)data *** novelty of the proposed framework.lies in the integration of various techniques,where the fusion of deep learning(DL),traditional machine learning(ML)techniques,and enhanced classification models have been deployed using the curated *** analysis outcome proves that the proposed enhanced RF(ERF),enhanced DT(EDT)and enhanced LR(ELR)models for BC detection outperformed most of the existing models with impressive results.

关键词： Autoencoder breast cancer deep neural network convolutional neural network image processing machine learning deep learning

Bethanechol Remains the Preferred Drug in Suspected Underactive Bladder: Findings from Nation-Wide Prescription Analysis

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Open Journal of Urology 2024年第5期14卷 301-311页

作者： sanjay Vasant k.mble Anjana k.lpesh Yadav Maneesha Tark.shwar sharma Radha Ratnadeep Bhosle Department of Medical Services Samarth Life Sciences Pvt. Ltd. Mumbai India

Back.round: Bethanechol chloride, a cholinergic agonist, is often prescribed in suspected underactive bladders to improve detrusor contractility, despite its limited clinical efficacy. We investigated the usage pattern of bethanechol in actual practice with the understanding that it would enable the physicians to mak. an informed decision on the coherent use of bethanechol. Methods: A nation-wide survey was carried out to obtain the responses of the urologists. Out of the 755 urologists approached, 630 survey responses were considered for analysis. Results: Usage of bethanechol was advocated as very common [318 (50.48%)], common [200 (31.75%)], not so common [107 (16.98%)], and rare [5 (0.79%)] in postoperative urinary retention, where it was preferred either exclusively [255 (40.48%)] or along with alpha block.rs [247 (39.21%)]. Predilection to use alpha-block.r [247 (39.21%)], alpha-block.r plus naloxone [4 (0.64%)], naloxone [1 (0.16%)], alpha-block.r plus bethanechol plus naloxone [1 (0.16%)] was also observed. It was also preferred individually in pathologies causing urinary retention such as benign prostatic hyperplasia [125 (19.84%)], diabetic neuropathy [82 (13.02%)], neurological diseases [69 (10.95%)], senile bladder [14 (2.22%)], drugs [13 (2.06%)], and infective/inflammatory conditions [6 (0.95%)]. Other [321 (50.95%)] physicians opted to prescribe bethanechol in two or more of the enumerated indications. Bethanechol was prescribed orally as 25 mg thrice daily [441 (70.00%)], 50 mg thrice daily [86 (13.65%)], 25 mg four times daily [59 (9.37%)], and many “strongly agree” and “agree” that its sustained release formulation may offer better treatment compliance [565 (89.68%)], safety [548 (86.99%)], and efficacy [544 (86.35%)]. Conclusion: Bethanechol was the most prescribed drug for the management of postoperative urinary retention and other pathologies suspected to cause underactive bladder.

关键词： Bethanechol Benign Prostatic Hyperplasia Detrusor Underactivity Urinary Retention Underactive Bladder

In-hospital outcomes in COVID-19 patients with non-alcoholic fatty liver disease by severity of obesity:Insights from national inpatient sample 2020

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World Journal of Hepatology 2024年第6期16卷 912-919页

作者： Sashwath Srik.nth Vibhor Garg Lak.hmi Subramanian Jyoti Verma Hansik. sharma Harroop Singh k.air Shrenil A k.vathia Jithin k.lli Teja Nik.il Sai Vasireddy k.mar Anmol Dhanush k.lli Shruti sanjay Bodhank.r Sobya Hashmi Shaylik. Chauhan Rupak.Desai Department of Medicine ECU Health Medical CenterGreenvilleNC 27834United States Department of Medicine Jacobi Medical Center/Albert Einstein College of MedicineBronxNY 10461United States Department of Medicine North Alabama Medical CentreFlorenceAL 35630United States Department of General Medicine Gandhi Medical CollegeSecunderabad 500003TelanganaIndia Department of Medicine Government Medical CollegePatiala 147001PunjabIndia Department of Medicine B.J.Medical CollegeAhmedabad 380016GujaratIndia Department of Medicine JSS Medical CollegeMysore 570015KarnatakaIndia Department of Internal Medicine Gandhi Medical CollegeSecunderabad 500003TelanganaIndia Department of Medicine Kasturba Medical CollegeManipal 575001KarnatakaIndia Clinical Extern Department of Internal MedicineBeaumont HospitalDearbornMI 48124United States Department of Internal Medicine Geisinger Health SystemWilkes-BarrePA 18702United States Independent Researcher AtlantaGA 30079United States

BACk.ROUND Non-alcoholic fatty liver disease(NAFLD)increases the risk.of cardiovascular diseases independently of other risk.***,data on its effect on cardiovascular outcomes in coronavirus disease 2019(COVID-19)hospitalizations with varied obesity levels is *** management and patient care depend on understanding COVID-19 admission results in NAFLD patients with varying obesity *** To study the in-hospital outcomes in COVID-19 patients with NAFLD by severity of *** COVID-19 hospitalizations with NAFLD were identified using International Classification of Disease-10 CM codes in the 2020 National Inpatient Sample *** and Obesity Classes Ⅰ,Ⅱ,and Ⅲ(body mass index 30-40)were *** adverse cardiac and cerebrovascular events(MACCE)(all-cause mortality,acute myocardial infarction,cardiac arrest,and strok.)were compared between *** regression analyses adjusted for sociodemographic,hospitalization features,and *** Our analysis comprised 13260 hospitalizations,7.3% of which were overweight,24.3% Class Ⅰ,24.1% Class Ⅱ,and 44.3% Class Ⅲ.Class Ⅲ obesity includes younger patients,black.,females,diabetics,and hypertensive *** multivariable logistic analysis,Class Ⅲ obese patients had higher risk. of MACCE,inpatient mortality,and respiratory failure than Class Ⅰ obese *** Ⅱ obesity showed increased risk. of MACCE,inpatient mortality,and respiratory failure than Class I,but not *** obesity classes had non-significant risk. of MACCE,inpatient mortality,and respiratory failure compared to the overweight *** Class Ⅲ obese NAFLD COVID-19 patients had a greater risk.of adverse outcomes than class Ⅰ.Using the overweight group as the reference,unfavorable outcomes were not significantly *** obesity had a greater risk.of MACCE regardless of the referent group(overweight or Class Ⅰ obese)compared to overweight NAFLD patients admitte

关键词： Non-alcoholic fatty liver disease Obesity Obese Body mass index Major adverse cardiac and cerebrovascular events Mortality Acute myocardial infarction Cardiac arrest Strok.

Cognitive Radios： A Survey On Spectrum Sensing, Security and Spectrum Handoff

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China Communications 2017年第11期14卷 185-208页

作者： Vishak.a Ramani sanjay k.sharma ECE Department University Institute of Technology Rajiv Gandhi Proudyogiki Vishwavidyalaya Ringgold Standard Institution Airport Bypass Road Bhopal Madhya Pradesh Bhopal Bhopal 462036 India

Pervasive wireless computing and communication have created an ever-increasing demand for more radio spectrum. Since, most of the spectrum is underutilized, it motivated the introduction of the concept of cognitive radios, a dynamic spectrum access enabling technology. The first stage of cognitive radio is to sense the environment and determine which parts of the spectrum are available. This is achieved through spectrum sensing. However, spectrum sensing poses the most fundamental challenge in cognitive radios. Moreover, cognitive radios suffer from many vulnerabilities and the security attack. can severely degrade the performance of cognitive radios. This paper surveys state-of-theart research on spectrum sensing and security threats in cognitive radios. Lastly, we also consider the analysis of issues related to spectrum handoffs in cognitive radios.

关键词： cogntive radio spectrum sesning security spectrum handoff

Circular RNA: The evolving potential in the disease world

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World Journal of Medical Genetics 2024年第1期12卷 1-16页

作者： Aarti sharma Cherry Bansal k.ran Lata sharma Ashok.k.mar Department of Research Mayo Clinic ArizonaPhoenixAZ 85054United States Department of Pathology Dr.S Tantia Medical CollegeHospital and Research CenterSri Ganganagar 335002RajasthanIndia Department of Pathology Baylor College of MedicineHoustonTX 77030United States Department of Surgical Gastroenterology Sanjay Gandhi Post Graduate Institute of Medical SciencesLucknow 226014Uttar PradeshIndia

Circular RNAs(circRNAs),a new star of noncoding RNAs,are a group of endogenous RNAs that form a covalently closed circle and occur widely in the mammalian *** circRNAs are conserved throughout species and fre-quently show stage-specific expression during various stages of tissue *** were a mystery discovery,as they were initially believed to be a product of splicing errors;however,subsequent research has shown that ci-rcRNAs can perform various functions and help in the regulation of splicing and transcription,including playing a role as microRNA(miRNA)*** the application of high throughput next-generation technologies,circRNA hotspots were *** are emerging indications that explain the association of circRNAs with human diseases,lik. cancers,developmental disorders,and in-flammation,and circRNAs may be a new potential biomark.r for the diagnosis and treatment outcome of various diseases,including *** the discoveries of miRNAs and long noncoding RNAs,circRNAs are now acting as a novel re-search entity of interest in the field of RNA disease *** this review,we aim to focus on major updates on the biogeny and metabolism of circRNAs,along with their possible/established roles in major human diseases.

关键词： Circular RNAs Cancer MicroRNA sponges Biomark.rs Long noncoding RNA RNA biology

Numerical Investigation of Convective Heat Transfer and Friction in Solar Air Heater with Thin Ribs

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Computer Modeling in Engineering & Sciences 2018年第3期114卷 295-319页

作者： sanjay k.sharma V.R.k.lamk.r VNIT Nagpur

The three-dimensional numerical investigation of an incompressible flow through rib roughened solar air heater is carried out.A combination of thin transverse and truncated ribs is attached on the absorber plate to study its effect on the heat transfer and friction *** parameters in the form of Reynolds number(Re)of 4000-16000,relative roughness pitch(P/e)of 8-18 and relative roughness height(e/Dh)of 0.0366-0.055 is considered for the *** CFD code ANSYS FLUENT is used to solve the governing equations of turbulent *** RNG k.εturbulence model is used to solve the transport equations with enhanced wall treatment,k.eping the Y+<*** maximum enhancement ratio of the Nusselt number and friction factor obtained is 1.91 and 3.61 *** detailed investigation on average heat transfer,friction factor and flow structures have been discussed.

关键词： CFD 3D heat transfer friction factor