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Association of the neutrophil-to-lymphocyte ratio and prostate cancer detection rates in patients via contemporary multi-core prostate biopsy

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Asian Journal of Andrology 2016年第6期18卷 937-941页

作者： Jong Jin Oh Ohsung Kwon Jung Keun lee Seok-Soo Byun Sang Eun lee sangchul lee Sung Kyu Hong Department of Urology Seoul National University Bundang Hospital Seongnam Korea.

The aim of this study was to determine whether the neutrophil-to-lymphocyte ratio （NLR）, a measure of the systemic inflammatory response is associated with the overall prostate cancer detection rate in men who underwent contemporary multi （〉12）-core transrectal ultrasound （TRUS） biopsy. We reviewed the records of 3913 patients with initial prostate-specific antigen （PSA） levels ranging from 4 to 10 ng ml^-1 who underwent TRUS-guided prostate biopsy between April 2006 and May 2014. NLR was calculated by prebiopsy neutrophil and lymphocyte counts. We excluded patients who had evidence of acute prostatitis, a history of prostate surgery, and any systemic inflammatory disease. A multivariate logistic regression model was used to analyze prostate cancer detection. After adjusting for confounding factors, predictive values were determined according to the receiver operating characteristic-derived area under the curve, both including and excluding the NLR variable. In univariate analyses, NLR was a significant predictor of prostate cancer detection （P 〈 0.001）. In multivariate analyses, a higher NLR was significantly associated with prostate cancer detection after adjusting for other factors （OR = 1.372, P = 0.038）. The addition of NLR increased the accuracy from 0.712 to 0,725 （P = 0.005） in the multivariate model for prostate cancer detection. NLR may be a potentially useful clinical marker in the detection of prostate cancer among men with a PSA level in the 4-10 ng ml^-1 range. These findings are derived from a retrospective analysis and should be validated in larger populations through prospective studies.

关键词： inflammation lymphocyte neutrophil prostate biopsy prostate cancer

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Development and validation of a clinical nomogram predicting bladder outlet obstruction via routine clinical parameters in men with refractory nonneurogenic lower urinary tract symptoms

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Asian Journal of Andrology 2019年第5期21卷 486-492页

作者： Young Ju lee Jung Keun lee Jung Jun Kim Hak Min lee Jong Jin Oh sangchul lee Sang Wook lee Jeong Hyun Kim Seong Jin Jeong Department of Urology Seoul National University Bundang HospitalSeongnam 13620Korea Department of Urology Kangwon National University School of MedicineChuncheon 24341Korea

We aimed to develop and validate a clinical nomogram predicting bladder outlet obstruction(BOO)solely using routine clinical parameters in men with refractory nonneurogenic lower urinary tract symptoms(LUTS).A total of 750 eligible patient ≥50 years of age who had previously not responded(International Prostate Symptom Score[IPSS]improvement2 cmH20 ml^-1 s^-1.A stepwise multivariable logistic regression analysis was conducted to determine the predictors of BOO,and^-coefficients of the final model were selected to create a clinical *** final multivariable logistic regression model showed that age,IPSS,maximum urinary flow rate,postvoid residual volume,total prostate volume,and transitional zone index were significant for predicting BOO;these candidates were used to develop the final *** discrimination performance of the nomogram was 88.3%(95%Cl:82.7%-93.0%,P<0.001),and the nomogram was reasonably we 11-fitted to the ideal line of the calibration *** nt split-sample validation revealed 80.9%(95%Cl:75.5%-84.4%,P<0.001)*** proposed BOO nomogram based solely on routine clinical parameters was accurate and validated *** nomogram may be useful in determining further treatment,primarily focused on prostatic surgery for BOO,without impeding the detection of possible BOO in men with LUTS that is refractory to empirical medications.

关键词： benign prostatic hyperplasia bladder outlet obstruction lower urinary tract symptoms no mogram urodynamics

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Contemporary trends in radical prostatectomy and predictors of recovery of urinary continence in men aged over 70 years:comparisons between cohorts aged over 70 and less than 70 years

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Asian Journal of Andrology 2020年第3期22卷 280-286页

作者： Young Ju lee Jin-Woo Jung sangchul lee Sang Wook lee Jeong Hyun Kim Sung Kyu Hong Seok-Soo Byun Sang Eun lee Seong Jin Jeong Departme nt of Urology Seoul National University Bundang HospitalSeongnam 13620Korea Department of Urology Catholic Kwan dong Univerisity International St.Mary's HospitalIncheon 22711Korea Department of Urology Kangwon National University School of MedicineChuncheon 24341Korea.

We evaluated contemporary trends in radical prostatectomy(RP)in men aged>70 years and investigated associations of selected variables with recovery of urinary continence(UC)in two age groups:>70 and70 years[n=610]vs70 years gradually increased up to 30.0%,and the rate of robot-assisted RP and neurovascular bundle(NVB)saving increased continually to 80.0%and 67.4%of older patients,*** the rate of recovery of UC within 12 months(3 months)in patients aged>70 years was lower than that in those aged S70 years(81.5%[52.6%]vs 88.6%[60.9%],respectively;both P70 ***,unlike younger patients,only variables(age and MUL),possibly associated with the inhere nt fun ction of the urinary sphi ncter,were predictors of recovery of UC in patients aged>70 years.

关键词： elderly predictor prostate cancer radical prostatectomy urinary incontinence

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Does prostate-specific antigen (PSA)mass or free PSA mass improve the accuracy of predicting total prostate volume in relation to obesity in men with biopsy-proven benign prostatic hyperplasia?

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Asian Journal of Andrology 2019年第1期21卷 86-91页

作者： Jin-Woo Jung young Dong Yu Young Ju lee Jung Jun Kim Hak Min lee Jong Jin Oh sangchul lee Sang Wook lee Sang Eun lee Seong Jin Jeong Department of Urology Catholic Kwandong Univerisity International St.Mary's HospitalIncheon 22711Korea Department of Urology Seoul National University Bundang HospitalSeongnam 13620Korea Department of Urology Kangwon National University School of MedicineChuncheon 24341Korea

We evaluated whether the prostate-specific antigen (PSA)mass or free PSA (fPSA)mass (i.e.,absolute amount of total circulating PSA or fPSA protein,respectively),versus serum PSA or fPSA concentration,improves the accuracy of predicting the total prostate volume (TPV)in relation to *** men whose multicore (≥12)transrectal prostate biopsy was negative,586 who had a PSA of <10 ng ml^-1 and underwent the fPSA test prior to biopsy were *** PSA mass or fPSA mass (pg)was calculated by multiplying the serum level by plasma *** each TPV cut-off point (30 ml,40 ml,and 50 ml),the areas under the receiver operating characteristics curve (AUCs)of each variable were compared in obesity-based *** of fPSA and fPSA mass for predicting TPV were significantly larger than those for PSA and PSA mass by 8.7%-12.1%at all cut-off points. Subgroup analyses based on obesity showed that,although PSA mass and fPSA mass enhanced accuracy by 4%(P =0.031)and 1.8%(P =0.003),respectively,for determining TPVs of ≥30 ml and ≥50 ml in obese and overweight men,they did not improve the accuracy in most other combinations of the degrees of obesity with TPV cut-off ***,compared with serum PSA or fPSA,the absolute amount of PSA or fPSA protein mass improved the accuracy of predicting TPV in obese men very minimally and only for certain TPV cut-off ***,these indicators may not provide clinically meaningful improvement in predicting TPV in obese men.

关键词： benign prostatic hyperplasia obesity prostate volume prostate-specific antigen mass

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Understanding pediatric surgical needs in North Korea: a modeling analysis

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World Journal of Pediatric Surgery 2024年第1期7卷 47-53页

作者： Phillip J Hsu sangchul Yoon Kee B Park University of Michigan Ann ArborMichiganUSA Department of Global Health and Social Medicine Harvard Medical SchoolBostonMassachusettsUSA Department of Medical Humanitiesand Social Sciences Yonsei University SeoulSouth Korea

Background Sixty-five percent of children worldwide lack access to surgical care,the majority of whom live in low-income and middle-income countries(LMiCs).Developing surgical infrastructure requires information on surgical need;however,this information is often limited in *** Korea(Democratic People's Republic of Korea,DPRK)has a low amount of publicly available ***,we analyzed available modeled data to understand the causes of pediatric deaths due to conditions treatable with surgery in *** We used World Bank data and models from the Institute for Health Metrics and Evaluation to identify causes of pediatric deaths affecting pediatric patients(age<20 years).We compared mortality of disease between DPRK and countries with similar economic *** Between 1990 and 2019,the number of overall pediatric deaths has *** 2019,32.2%of allpediatric deaths in DPRK were caused by surgical *** leading categories of surgical conditions were injuries(53.9%),congenital conditions(34.2%),tumors(8.8%),and abdominal conditions(3.2%).DPRK has a lower relative rate of pediatric deaths compared with other LMICs with similar gross domestic product per ***,it has a higher relative rate of pediatric deaths due to conditions requiring treatment with *** injuries contribute significantly to the high rate of pediatric deaths in *** Although DPRK may be allocating overall resources toward pediatric healthcare more efficiently than economic peers,DPRK may benefit from improvement in pediatric surgical *** availability of data and close international collaboration could be potential solutions to bridge this gap.

关键词： pediatric surgical injuries

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Erratum to: Enzyme-amplified SERS immunoassay with Ag-Au bimetallic SERS hot spots

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Nano Research 2021年第3期14卷 895-895页

作者： Xuan-Hung Pham Eunil Hahm Tae Han Kim Hyung-Mo Kim Sang Hun lee sangchul lee Homan Kang Ho-Young lee Dae Hong Jeong Hak Soo Choi Bong-Hyun Jun Department of Bioscience and Biotechnology Konkuk UniversitySeoul143-701Republic of Korea Department of Urology Seoul National University Bundang HospitalSeongnam13620Republic of Korea Gordon Center for Medical Imaging Department of RadiologyMassachusetts General Hospital and Harvard Medical SchoolBostonMA02114USA Department of Chemistry Education Seoul National UniversitySeoul151-742Republic of Korea

Erratum to Nano Research 2020,13(12):3338-3346 htts://***/00.1007/s12274-020-3014-3 One author name and corresponding affiliation of the original version of this article were unfortunately mislabeled.

关键词： SERS bimetallic

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Technological requirements of profile machining

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第9期7卷 1461-1466页

作者： PARK sangchul Department of Industrial Information & Systems Engineering Ajou University Suwon 443-749 Korea

The term ‘profile machining’ is used to refer to the milling of vertical surfaces described by profile curves. Profile machining requires higher precision (1/1000 mm) than regular 3D machining (1/100 mm) with the erosion of sharp vertices should being especially avoided. Although, profile machining is very essential for making trimming and flange dies, it seldom brought into focus. This paper addresses the technological requirements of profile machining including machining width and depth control, minimizing toolware, and protecting sharp vertices. Issues of controller alarms are also addressed.

关键词： Profile machining Technological requirements Protecting sharp vertices

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Characteristics of odorous carbonyl compounds in the ambient air around a fishery industrial complex of Yeosu,Korea

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Journal of Environmental Sciences 2012年第10期24卷 1785-1789页

作者： Zhongkun Ma Junmin Jeon Sangchai Kim sangchul Jung Woobum lee Seonggyu Seo Department of Environmental System Engineering Chonnam National University50 Daehak-roYeosu 550-749Republic of Korea Department of Civil&Environmental Engineering Suncheon First CollegeSan 9-3 Dokwol-DongSuncheon 540-744Republic of Korea Department of Environmental Education Molcpo National University61 Dorim RiCheonggye MyeonMuan 534-729Republic of Korea Department of Environmental Engineering Sunchon National University315 Maegok-DongSuncheon 540-742Republic of Korea

In this study, the amounts of odorous carbonyl compounds （OCCs） including acetaldehyde （Acet-A）, propionaldehyde （Pron-A）, butylaldehyde （Buty-A）, iso-valeric aldehyde （Iso-Vale-A） and n-valeric aldehyde （N-Vale-A） emitted from a fishery industrial complex near the exhibition facilities of ＂Expo 2012 Yeosu Korea＂ were measured. Acet-A was found to be the most abundant OCC, and the total concentrations of the OCCs were the highest in the summer. However, due to vehicular exhaust and photochemical reactions, the concentrations of some of the OCCs presented their highest levels in the fall. A significant correlation between Acet-A and Buty-A was found at the major fishery facilities （r = 0.816, p = 1.87E-15, n = 60） and at the border areas （r = 0.809, p = 3.40E-12, n = 48） of this fishery industrial complex. The concentrations of OCCs at the border areas were not worse than those at the urban areas in other places, indicating that the concentrations of ambient OCCs at the border areas were not greatly influenced by manmade activities.

关键词： fishery industrial complex odorant carbonyl compounds acetaldehyde seasonal variation

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含时变滞后的不确定系统的时滞相关型鲁棒控制设计(英文)

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控制理论与应用 2003年第2期20卷 261-264,268页

作者：岳东 WON sangchul 南京师范大学控制科学与工程系江苏南京221008 韩国蒲项工业大学

研究含时变滞后的不确定系统的控制综合问题 .基于Lyapunov方法提出了一种含滞后补偿的鲁棒控制设计方法 .闭环稳定性条件由一组线性矩阵不等式表示 .在这些条件中给出了稳定性和滞后以及其导数之间的关系 .实例显示 ,利用提供的方法所... 详细信息

研究含时变滞后的不确定系统的控制综合问题 .基于Lyapunov方法提出了一种含滞后补偿的鲁棒控制设计方法 .闭环稳定性条件由一组线性矩阵不等式表示 .在这些条件中给出了稳定性和滞后以及其导数之间的关系 .实例显示 ,利用提供的方法所给出的结果比以往文献给出的结果保守性小 .

关键词：不确定系统时滞时滞相关型鲁棒控制设计 Lyapunov函数控制综合问题

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Multiple Coils Recognition System for Unmanned Crane Using Stereo Vision

Multiple Coils Recognition System for Unmanned Crane Using S...

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技术创新与循环经济——第二届宝钢学术年会

作者： Dowan KIM Sehoon KIM Sungjin KIM sangchul WON Steel processing Automation Research Center.Pohang University of Science and Technology

＜正＞In this paper,we present a multiple coils recognition system for unmanned crane using stereo *** initial position and orientations of multiple coils are recognized by the edge-based 2 D image processing *** 3 D map of the coils is constructed by stereo vision system which is implemented on FPGA chips for real time *** disparity values are generated from the left and right images using stereo matching algorithm at high *** the precise position and orientations are found using a surface segmentation *** proposed system is successfully developed and tested at coil yard in POSCO Pohang steel works for unmanned crane and shows satisfactory performance.

关键词： stereo matching surface segmentation unmanned crane

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