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Electrogastrography associated with symptomatic changes after prokinetic drug treatment for functional dyspepsia

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World Journal of Gastroenterology 2012年第41期18卷 5948-5956页

作者： Hyun chul Lim sang In lee Jiande DZ Chen Hyojin Park Department of Internal Medicine Yonsei University College of MedicineSeoul 120-752South Korea Division of Gastroenterology Department of Internal MedicineUniversity of Texas Medical BranchGalvestonTX 77555United States

AIM:To evaluate the effect of prokinetic drugs on electrogastrography(EGG) parameters according to symptomatic changes in patients with functional dyspepsia(FD).METHODS:Seventy-four patients with FD were prospectively enrolled in this study between December 2006 and December *** surveyed the patients using a questionnaire on dyspeptic symptoms before and after an 8-wk course of prokinetic drug *** also measured cutaneous pre-prandial and postprandial EGG recordings including percentage of gastric waves(normogastria,bradygastria,tachygastria),dominant frequency(DF),dominant power(DP),dominant frequency instability coefficient(DFIC),dominant power instability coefficient(DPIC),and the ratio of post-prandial to fasting in DP before and after the 8-wk course of prokinetic drug ***:Fifty-two patients(70%) achieved symptomatic improvement after prokinetic drug *** who had normal gastric slow waves showed symptom improvement group after *** DF showed a downward trend in the symptom improvement group,especially in the itopride ***-prandial DP was increased regardless of symptom improvement,especially in the itopride group and mosapride ***-prandial DFIC and DPIC in the symptom improvement group were significantly increased after the *** EGG power ratio was increased after treatment in the symptom improvement group(0.50 ± 0.70 vs 0.93 ± 1.77,P = 0.002),especially in the itopride and levosulpiride ***:Prokinetics could improve the symptoms of FD by regulating gastric myoelectrical activity,and EGG could be a useful tool in evaluating the effects of various prokinetics.

关键词：不良症状药物治疗治疗功能消化不良稳定系数功率比问卷调查莫沙必利

Effect of Sub-T_g Annealing on the Corrosion Resistance of the Cu–Zr Amorphous Alloys

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Acta Metallurgica Sinica(English Letters) 2018年第3期31卷 273-280页

作者： sang-Soo Shin Hong-Kyu Kim Jae-chul lee Ik-Min Park Department of Materials Science and Engineering Pusan National University Advanced Analysis Center Korea Institute of Science and Technology Department of Materials Science and Engineering Korea University

Despite the economy of material cost and excellent toughness of Cu-based amorphous alloys,especially CusoZrso,their poor corrosion resistance to a chloride medium limits their widespread *** this study,corrosion tests were performed on the CusoZrso amorphous alloy with different degrees of short-range order,which were prepared by annealing below the glass transition temperature（Tg）.It was found that the corrosion resistance of amorphous alloys is improved to a significant level when the alloys were heated below *** studies showed that thermally activated relaxation process of created disorder,which occurs during sub-Tg annealing,is responsible for the improvement in the corrosion *** dynamics simulations performed on the Cu-Zr amorphous alloys demonstrated that the relaxation process of the alloys is associated with the formation of energetically stable icosahedra and icosahedron-like *** study highlights the effects of sub-Tg annealing on the improvement in the corrosion resistance of the amorphous alloys from the viewpoint the relaxation process of the short-range orders.

关键词： Amorphous alloys Corrosion Annealing Molecular dynamics Electrochemical performance

Prevalence of focal lamina cribrosa defects in eyes with pachychoroid disease spectrum

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International Journal of Ophthalmology(English edition) 2022年第1期15卷 77-82页

作者： Hae Min Kang Na Eun lee Jeong Hoon Choi Hyoung Jun Koh Sung chul lee Harvard School of Public Health BostonMA 02115USA Catholic Kwandong University Incheon 22711Republic of Korea Gongdoek Seoul Eye Clinic Seoul 04214Republic of Korea Choikang Seoul Eye Clinic Seoul 01110Republic of Korea Institute of Vision Research Department of OphthalmologyYonsei University College of MedicineSeoul 03722Republic of Korea Konyang University Hospital Daejeon 35365Republic of Korea

AIM:To determine the prevalence of focal lamina cribrosa(LC)defect among patients with pachychoroid disease spectrum(PDS)in the absence of peripapillary ***:This retrospective,cross-sectional study comprised of 180 patients with PDS,including polypoidal choroidal vasculopathy(PCV),central serous chorioretinopathy,and pachychoroidal *** records and optic ner ve head evaluations conducted using spectral-domain optical coherence tomography with enhanced depth imaging were *** a control group,236 patients who underwent ophthalmologic evaluation for vitreous floaters,without obvious ocular disease,were also ***:The mean age of the PDS group,which included 118 male patients(65.6%),was 57.4±11.1 *** was no significant difference between the two groups in age(P=0.710)or sex(P=0.248).Six patients(3.3%)in the PDS group and none in the control group showed focal LC defect(P=0.318).Among the six patients with focal LC defect in the PDS group,four eyes had PCV,one eye was the fellow eye of a PCV eye,and one eye had pachychoroidal ***:Focal LC defect can be defected in patients with PDS in the absence of peripapillar y ***,the prevalence of focal LC defect was not different significantly between PDS patients and those who did not have PDS.

关键词： central serous chorioretinopathy lamina cribrosa pachychoroid polypoidal choroidal vasculopathy

Magnetic wallpaper Dirac fermions and topological magnetic Dirac insulators

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npj Computational Materials 2023年第1期9卷 1695-1702页

作者： Yoonseok Hwang Yuting Qian Junha Kang Jehyun lee Dongchoon Ryu Hong chul Choi Bohm-Jung Yang Center for Correlated Electron Systems Institute for Basic Science(IBS)Seoul 08826Korea Department of Physics and Astronomy Seoul National UniversitySeoul 08826Korea Center for Theoretical Physics(CTP) Seoul National UniversitySeoul 08826Korea

Topological crystalline insulators(TCIs)can host anomalous surface states which inherits the characteristics of crystalline symmetry that protects the bulk ***,the diversity of magnetic crystalline symmetries indicates the potential for novel magnetic TCIs with distinct surface ***,we propose a topological magnetic Dirac insulator(TMDI),whose two-dimensional surface hosts fourfold-degenerate Dirac fermions protected by either the p'_(c)4mm or p40 g0 m magnetic wallpaper *** bulk topology of TMDIs is protected by diagonal mirror symmetries,which give chiral dispersion of surface Dirac fermions and mirror-protected hinge *** propose candidate materials for TMDIs including Nd_(4)Te_(8)Cl_(4)O_(2)0 and DyB_(4) based on first-principles calculations,and construct a general scheme for searching TMDIs using the space group of paramagnetic parent *** theoretical discovery of TMDIs will facilitate future research on magnetic TCIs and illustrate a distinct way to achieve anomalous surface states in magnetic crystals.

关键词： Dirac topological protected

Antiphospholipid syndrome with renal and splenic infarction after blunt trauma:A case report

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World Journal of Clinical Cases 2022年第26期10卷 9404-9410页

作者： Na-A lee Eui-Sung Jeong Hyun-Seok Jang Yun-chul Park Ji-Hyoun Kang Jung-chul Kim Young-Goun Jo Division of Trauma Department of SurgeryChonnam National University Medical School and HospitalGwangju 61469South Korea Division of Rheumatology Department of Internal MedicineChonnam National University Medical School and HospitalGwangju 61469South Korea

BACKGROUND In trauma patients,bleeding is an immediate major *** the same time,there are few cases of acute vascular occlusion after blunt trauma,and it is unclear what assessment and diagnosis should be considered for these ***,we describe a patient diagnosed with antiphospholipid syndrome after a hypercoagulable workup for acute renal and splenic vascular occlusion due to blunt *** SUMMARY A 20-year-old man was admitted to the emergency department with abdominal pain after hitting a tree while riding a sled 10 h *** had no medical *** investigations revealed occlusion of the left renal artery with global infarction of the left kidney and occlusion of branches of the splenic artery with infarction of the central portion of the *** revascularization of the left renal artery occlusion through percutaneous transluminal angioplasty failed due to difficulty in passing the wire through the total *** the presence of acute multivascular occlusions in a young man with low cardiovascular risk,additional laboratory tests were performed to evaluate *** results suggested a high possibility of antiphospholipid *** with a subcutaneous injection of enoxaparin was started and changed to oral warfarin after two *** diagnosis was confirmed,and he continued to visit the rheumatology outpatient clinic while taking *** A hypercoagulable workup can be considered in trauma patients with acute multivascular occlusion,especially in young patients with low cardiovascular risk.

关键词： Wounds and injuries Wounds Nonpenetrating Antiphospholipid syndrome Renal artery obstruction Splenic infarction Case reports

High-performance non-enzymatic glucose sensor based on Co_(3)O_(4)/rGO nanohybrid

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Rare Metals 2023年第9期42卷 3046-3053页

作者： Ling-Yun Xiong You-Joong Kim Won-Cheol Seo Han-Kyu lee Woo-chul Yang Wan-Feng Xie Department of Physics Dongguk UniversitySeoul04620South Korea School of Electronics and Information Industry Joint Center for Ocean Observation and Broadband CommunicationQingdao UniversityQingdao266071China

There has been substantial interest in designing and fabricating electrochemical non-enzyme sensors for glucose detection with a focus on the nanocomposites used between metal oxide and the two-dimensional *** this work,Co_(3)O_(4)/reduced graphene oxide(rGO)nanocomposite was obtained and used as a modified electrochemical electrode for the detection of trace *** to the results,the electrocatalytic performances of Co_(3)O_(4)nanoparticles for the oxidation of glucose were substantially enhanced with the addition of a small amount of r ***,the Co_(3)O_(4)/r GO modified electrode exhibited a sensitivity of 82μA·mmol^(-1)·cm^(-2),a detection limit of 50μmol·L^(-1)(signal noise ratio(S/N)=3),and a fast response time of about 1 s under optimal *** enhanced performances of the Co_(3)O_(4)/r GO modified electrode are attributable to the high absorption oxygen(O_(Ads))and synergistic effect between Co_(3)O_(4)and r *** results indicate that Co_(3)O_(4)/r GO nanocomposite is a promising candidate for being used as the active material in real-world electrochemical biosensors.

关键词： Co_(3)O_(4) Reduced graphene oxide(rGO) Glucose Electrocatalytic

Machine Learning for Detecting Blood Transfusion Needs Using Biosignals

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Computer Systems Science & Engineering 2023年第8期46卷 2369-2381页

作者： Hoon Ko chul Park Wu Seong Kang Yunyoung Nam Dukyong Yoon Jinseok lee Department of Biomedical Engineering College of Electronics and InformationKyung Hee UniversityYongin17104Korea Department of Internal Medicine Wonkwang University School of MedicineIksan54538Korea Department of Trauma Surgery Jeju Regional Trauma CenterCheju Halla General HospitalJeju63127Korea Department of Computer Science and Engineering Soonchunhyang UniversityAsan31538Korea Department of Biomedical Systems Informatics Yonsei University College of MedicineYongin03722Korea

Adequate oxygen in red blood cells carrying through the body to the heart and brain is important to maintain *** those patients requiring blood,blood transfusion is a common procedure in which donated blood or blood components are given through an intravenous ***,detecting the need for blood transfusion is time-consuming and sometimes not easily diagnosed,such as internal *** study considered physiological signals such as electrocardiogram(ECG),photoplethysmogram(PPG),blood pressure,oxygen saturation(SpO2),and respiration,and proposed the machine learning model to detect the need for blood transfusion *** the model,this study extracted 14 features from the physiological signals and used an ensemble approach combining extreme gradient boosting and random *** model was evaluated by a stratified five-fold crossvalidation:the detection accuracy and area under the receiver operating characteristics were 92.7%and 0.977,respectively.

关键词： Blood transfusion ECG PPG pulse transit time blood pressure machine learning

Effects of H_2/CO/CH_4 syngas composition variation on the NO_x and CO emission characteristics in a partially-premixed gas turbine combustor

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Science China(Technological Sciences) 2016年第12期59卷 1804-1813页

作者： lee Min chul Department of Safety Engineering College of EngineeringFire Disaster Prevention Research CenterIncheon National University

This paper reports the effects of variations in the fuel composition of H_2/CO/CH_4 syngas on the characteristics of NO_x and CO emissions in a partially-premixed gas turbine combustor. Combustion tests were conducted on a full range of fuel compositions by varying each component gas from 0% to 100% at heat inputs of 40 and 50 k Wth. Flame temperature, combustor liner temperature, ignition delay time, and flame structure were investigated computationally and experimentally to judge whether they are significant indicators of NO_x and CO formation. The characteristics of and reasons for NO_x and CO emissions were investigated by analyzing the emission mechanisms and relationships among fuel property, equivalence ratio, flame temperature, liner temperature, flame shape. The flame structures were investigated using the following flame visualization methods:(1) time-averaged OH* chemiluminescence and its Abel-deconvolution;(2) direct photography; and(3) instantaneous OH-PLIF. The flame structures were greatly changed by the fuel composition and heat input, and they were subjected to key affecting parameters of the temperatures of the flames and the liners. NO_x and CO emissions also largely varied according to fuel composition and heat input, showing neither linearly nor exponentially clear proportional trends toward the syngas compositions because of the singular conditions. For example, only the 100% CO flame at low load emitted lots of CO, whereas complete combustion was observed in other cases. However, the qualitative observations showed that the root causes of NO_x emission behaviors were flame temperature and flame structure, which were directly related to the residence time in the flame. Various sets of practical test results were obtained, and these results could contribute to the optimal selection of the fuel-feeding condition when fuel is changed from natural gas to syngas in order to minimize NO_x and CO emissions with stable combustion.

关键词：燃气轮机燃烧室 CO排放成分变化排放特性部分预混合成气 NOx 火焰温度

Multiple cranial nerve palsies with small angle exotropia following COVID-19 mRNA vaccination in an adolescent:A case report

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World Journal of Clinical Cases 2022年第33期10卷 12289-12294页

作者： Heejin lee Jun chul Byun Won Jae Kim Min Cheol Chang Saeyoon Kim Department of Pediatrics Yeungnam University Medical CenterDaegu 42415South Korea Department of Pediatrics Dongsan HospitalKeimyung University School of MedicineDaegu 42601South Korea Department of Ophthalmology Yeungnam University Medical CenterYeungnam University College of MedicineDaegu 42415South Korea Department of Physical Medicine and Rehabilitation Yeungnam University Medical CenterYeungnam University College of MedicineDaegu 42415South Korea Department of Pediatrics Yeungnam University Medical CenterYeungnam University College of MedicineDaegu 42415South Korea

BACKGROUND Several vaccines against the severe acute respiratory syndrome coronavirus 2 have been approved and widely distributed,raising public concerns regarding the side effects of immunization,as the incidence of *** many adverse events following the coronavirus disease 2019(COVID-19)vaccine have been reported,neurological complications are relatively ***,we report a rare case of multiple cranial palsies following COVID-19 vaccination in an adolescent *** SUMMARY A previously healthy,14-year-old Asian girl with facial palsy presented to the emergency department with inability to close the right eye or wrinkle right side of the forehead,and pain in the right *** had received second dose of the COVID-19 mRNA vaccine(Pfizer-BioNTech)18 days before onset of *** was diagnosed with Bell’s palsy and prescribed a steroid(1 mg/kg/day methylprednisolone)based on symptoms and magnetic resonance imaging ***,the next day,all sense of taste was lost with inability to swallow solid food;the gag reflex was *** diplopia was also *** to worsening of her condition,she was given high-dose steroids(1g/day methylprednisolone)for 3 days and then discharged with oral *** in the symptoms was noted 4 days post steroid treatment *** the most recent follow-up,her general condition was good with no symptoms except diplopia;ocular motility disturbances were ***,prism glasses were prescribed for diplopia *** Small-angle exotropia was observed in the facial,trigeminal,and glossopharyngeal nerve palsies,in our *** etiology of this adverse effect following vaccination was thought to be immunological.

关键词： SARS-CoV-2 COVID-19 COVID-19 vaccine Multiple cranial nerve palsies Facial nerve palsy Diplopia Exotropia Case report