检索结果-南通市图书馆

Clinical and laboratory profile in confirmed vs. suspected septic arthritis patients and its relevance in decision making: A comparative cross-sectional study

引用

Chinese Journal of Traumatology 2021年第2期24卷 94-99页

作者： sandeep knema Suman Kumar Basel Jose Austine Kiyana Mirza Department of Orthopaedic Surgery Jawaharlal Institute of Post Graduate Medical Education and ResearchPondicherry605006India Department of Orthopaedic Surgery Father Muller Medical CollegeMangalore575002India

Purpose:There were 10%e30%of patients with adult-onset septic arthritis(SA)exhibiting sterile synovial fluid(SF),and the uncertainty in the determining diagnosis of these patients posed a challenge in *** purpose of this study was to investigate the differences between confirmed(Newman A)and suspected(Newman B&C)SA in ***:This was a descriptive study with a cross-sectional study design conducted at a tertiary referral centre from July 2016 to February *** aged over 18 years presented to the emergency department with clinical features suggestive of SA and were scheduled to undergo arthrotomy and joint lavage by the treating surgeon were included in the *** with prosthetic joint infections and open joint injuries were ***’demographic data,clinical features and laboratory parameters were *** clinical and laboratory profile(blood and SF)of the adult patients presenting with features suggestive of SA based on Newman criteria was statistically analyzed by SPSS version 20 software and Microsoft *** categorical variables were expressed as proportions while the continuous variables were expressed as mean(SD)or median(IQR)depending upon the normality of *** difference between the two groups for categorical variables was assessed using the Chisquare test and the difference for continuous variables was assessed using the unpaired t-test and the Mann-Whitney test depending upon normality.A p value<0.05 was considered ***:Thirty-six patients were divided into confirmed(n¼19)or suspected(n¼17)SA for assessment based on SF *** median(IQR)age of the patients was 50 years(37e60 years).There was no significant difference in demographic,clinical and laboratory parameters between the concerned *** patients presented with *** the confirmed SA cases,8 were negative for C-reactive protein and 6 had synovial white blood cell count<50,*** species were

关键词： Synovial fluid Immunosuppressive agents Arthritis Infectious

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Contributions of type II and Ib/c supernovae to Galactic chemical evolution

引用

Research in Astronomy and Astrophysics 2014年第6期14卷 693-704页

作者： sandeep Sahijpal Department of Physics Panjab University

Type II and Ib/c supernovae （SNe II and Ib/c） have made major stellar nu- cleosynthetic contributions to the inventories of stable nuclides during chemical evolu- tion of the Galaxy. A case study is performed here with the help of recently developed numerical simulations of Galactic chemical evolution in the solar neighborhood to un- derstand the contributions of SNe II and Ib/c by comparing the stellar nucleosynthetic yields obtained by two leading groups in this field. These stellar nucleosynthetic yields differ in terms of their treatment of stellar evolution and nucleosynthesis. The formu- lation describing Galactic chemical evolution is developed with the recently revised solar metallicity of -0.014. Furthermore, the recent nucleosynthetic yields of stellar models based on the revised solar metallicity are also used. The analysis suggests that it could be difficult to explain, in a self-consistent manner, the various features asso- ciated with the elemental evolutionary trends over Galactic timescales by any single adopted stellar nucleosynthetic model that incorporates SNe II and Ib/c.

关键词： Sun: abundances - stars: evolution - stars: supernovae - Galaxy:abundance - Galaxy: formation - Galaxy: evolution - nucleosynthesis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Protracted zircon growth in migmatites and In situ melt of Higher Himalayan Crystallines:U-Pb ages from Bhagirathi valley, NW Himalaya,India

引用

Geoscience Frontiers 2019年第3期10卷 793-809页

作者： sandeep Singh Department of Earth Sciences Indian Institute of Technology Roorkee

The Higher Himalayan Crystallines(HHC), in western Garhwal, Uttarakhand are located in a regionalscale intracontinental ductile shear zone(15-20 km wide) bounded by the Main Central Thrust at the base, and the South Tibetan Detachment System at the top. The migmatite zone in the centre has the highest grade of metamorphism in the NW Himalayas and show evidence of flowage. Zircons extracted from samples of metasediment, migmatite, biotite granite and in situ partial melt(tourmaline-bearing leucogranite) along the Bhagirathi Valley, preserve U-Pb isotopic evidence of magmatic history, magma source and effects of the Himalayan orogeny in the region. Three distinct periods of zircon growth in the leucogranite record the episodic influx of magma between 46 Ma and 20 Ma indicating a time span of more than 25 Ma between the onset of fluid-fluxed partial melting in the mid-crustal intracontinental shear zone and the emplacement of the magma into the upper crust in a post-collisional extensional setting. Metamorphic zircon growth was initiated about 46 Ma, when the partial melts were generated as the migmatite zone was exhumed.

关键词： Himalayas Crustal anatexis Zircon SHRIMP U-Pb dating Migmatites Granites

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Linear and nonlinear propagation characteristics of multi-Gaussian laser beams

引用

Chinese Physics B 2020年第11期29卷 370-379页

作者： Naveen Gupta sandeep Kumar Lovely Professional University PhagwaraIndia

Theoretical investigation on the propagation characteristics of a new class of laser beams known as multi Gaussian(M.G)laser beams has been *** investigate the linear characteristics,propagation of the laser beam in vacuum has been ***,the nonlinear characteristics have been investigated in *** nonlinearity of the plasma has been modeled by relativistic mass nonlinearity of the plasma electrons in the field of laser *** is based on finding the semi analytical solution of the wave equation for the slowly varying envelope of the laser ***,the dynamical evolutions of the beam width and longitudinal phase of the laser beam have been investigated in detail.

关键词： self-focusing multi Gaussian self phase modulation self-channeling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Micromechanical experiments using a new inter-granule loading apparatus on gravel to ballast-sized materials

引用

Friction 2020年第1期8卷 70-82页

作者： Chitta Sai sandeep Kostas SENETAKIS City University of Hong Kong Hong Kong SARChina

Micromechanical and tribological studies of geological materials with a particular focus on their contact-mechanics behavior at the grain scale are currently a major interest in the engineering and geoscience disciplines. In this study, a new robust micromechanical apparatus developed at the City University of Hong Kong is described;it is capable of conducting inter-granule(or inter-particle) loading tests on fine gravel to ballast-sized materials of sizes as small as 5-10 mm to granules(or ballast) as big as 50 mm. The focus of our study is the description of the major technical features of the new apparatus and its performance and repeatability in conducting experiments on reference grains of chrome steel balls and glass balls;in addition, we conducted a preliminary set of experiments on crushed granitic rock, which is a material widely used in geotechnical and transportation infrastructure. The representative results of these experiments are presented in terms of the normal force-displacement relationship, friction, and tangential stiffness. The newly developed large-size apparatus is further compared with a well-established apparatus that can conduct micromechanical tests on sand-sized materials.

关键词： experimental micromechanics contact mechanics linear bearings inter‐particle friction granite debris flow ballast

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Piecewise linear programming approach to solve multi-objective matrix games with I-fuzzy goals

引用

Journal of Control and Decision 2021年第1期8卷 1-13页

作者： sandeep Kumar Department of Mathematics Ch.Charan Singh UniversityMeerut 250004Uttar PradeshIndia

The intuitionistic fuzzy set(I-fuzzy set)plays an effective role in game theory when players face‘neither this nor that’situation to set their *** study presents a maxmin–minmax solution to multi-objective two person zero-sum matrix games with I-fuzzy *** this article,a class of piecewise linear membership and non-membership functions for I-fuzzy goals is *** functions are more effective in real games because marginal rate of increase(decrease)of such membership functions(non-membership functions)is different in different intervals of tolerance ***,one numerical example is given to examine the effectiveness and advantages of the proposed results.

关键词： Intuitionistic fuzzy set multi-objective matrix game I-fuzzy goals maxmin-minmax solution piecewise linear function

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

2P3FL:A Novel Approach for Privacy Preserving in Financial Sectors Using Flower Federated Learning

引用

Computer Modeling in Engineering & Sciences 2024年第8期140卷 2035-2051页

作者： sandeep Dasari Rajesh Kaluri School of Computer Science Engineering and Information Systems Vellore Institute of TechnologyVellore632014India

The increasing data pool in finance sectors forces machine learning(ML)to step into new *** data has significant financial implications and is *** users data from several organizations for various banking services may result in various intrusions and privacy *** a result,this study employs federated learning(FL)using a flower paradigm to preserve each organization’s privacy while collaborating to build a robust shared global ***,diverse data distributions in the collaborative training process might result in inadequate model learning and a lack of *** address this issue,the present paper proposes the imple-mentation of Federated Averaging(FedAvg)and Federated Proximal(FedProx)methods in the flower framework,which take advantage of the data locality while training and guaranteeing global *** improves the privacy of the local *** analysis used the credit card and Canadian Institute for Cybersecurity Intrusion Detection Evaluation(CICIDS)***,recall,and accuracy as performance indicators to show the efficacy of the proposed strategy using FedAvg and *** experimental findings suggest that the proposed approach helps to safely use banking data from diverse sources to enhance customer banking services by obtaining accuracy of 99.55%and 83.72%for FedAvg and 99.57%,and 84.63%for FedProx.

关键词： Federated learning FedAvg FedProx flower framework privacy preservation financial sectors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insoluble drug delivery strategies: review of recent advances and business prospects

引用

Acta Pharmaceutica Sinica B 2015年第5期5卷 442-453页

作者： sandeep Kalepu Vijaykumar Nekkanti Department of Pharmaceutical Technology Shri Vishnu College of Pharmacy College of Pharmaceutical Sciences Western University of Health Sciences

The emerging trends in the combinatorial chemistry and drug design have led to the development of drug candidates with greater lipophilicity, high molecular weight and poor water solubility. Majority of the failures in new drug development have been attributed to poor water solubility of the drug. Issues associated with poor solubility can lead to low bioavailability resulting in suboptimal drug delivery. About 40% of drugs with market approval and nearly 90% of molecules in the discovery pipeline are poorly water-soluble. With the advent of various insoluble drug delivery technologies, the challenge to formulate poorly water soluble drugs could be achieved. Numerous drugs associated with poor solubility and low bioavailabilities have been formulated into successful drug products. Several marketed drugs were reformulated to improve ef fi cacy, safety and patient compliance. In order to gain marketing exclusivity and patent protection for such products, revitalization of poorly soluble drugs using insoluble drug delivery technologies have been successfully adopted by many pharmaceutical *** review covers the recent advances in the fi eld of insoluble drug delivery and business prospects.

关键词： Bioavailability Cocrystals Solubility Inclusion complexation Nanoparticles Self-emulsifying formulations Proliposomes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Role of betaine in liver disease-worth revisiting or has the die been cast?

引用

World Journal of Gastroenterology 2020年第38期26卷 5745-5748页

作者： sandeep Mukherjee Department of Medicine Creighton University Medical CenterDivision of GastroenterologyOmahaNE 68124United States

Nonalcoholic steatohepatitis(NASH)is an important indication for liver transplantation in many Western countries due to the epidemic of obesity and insulin ***,no medication is approved for NASH and risk factor modification is often *** the last decade,several clinical trials on NASH have been conducted with several ongoing and the future looks *** betaine(trimethyl glycine)was evaluated for NASH,results were mixed in the clinical trials in large part due to the quality of the *** seems reasonable to re-evaluate betaine in clinical trials for NASH and alcoholic liver disease due to its low cost,tolerability and mechanism of action.

关键词： Betaine Obesity Insulin resistance Nonalcoholic steatohepatitis Cirrhosis S-adenosyl homocysteine S-adenosyl methionine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecules against COVID-19:An in Silico Approach for Drug Development

引用

Journal of Electronic Science and Technology 2021年第1期19卷 14-24页

作者： Rhythm Bharti sandeep Kumar Shukla the Sri Venkateswara College University of DelhiNew Delhi 110021. The Institute of Nuclear Medicine and Allied Sciences Defence Research and Development OrganizationDelhi 110054

A large number of deaths have been caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)worldwide,turning it into a serious and momentous threat to public *** study tends to contribute to the development of effective treatment strategies through a computational approach,investigating the mechanisms in relation to the binding and subsequent inhibition of SARS-CoV-2 ribonucleic acid(RNA)-dependent RNA polymerase(RdRp).Molecular docking was performed to screen six naturally occurring molecules with antineoplastic properties(Ellipticine,Ecteinascidin,Homoharringtonine,Dolastatin 10,Halichondrin,and Plicamycin).Absorption,distribution,metabolism,and excretion(ADME)investigation was also conducted to analyze the druglike properties of these *** docked results have clearly shown binding of ligands to the SARS-CoV-2 RdRp ***,all ligands were found to obey Lipinski’s rule of *** results provide a basis for repurposing and using molecules,derived from plants and animals,as a potential treatment for the coronavirus disease 2019(COVID-19)infection as they could be effective therapeutics for the same.

关键词： Coronavirus disease 2019(COVID-19) drug repurposing,molecular docking natural therapeutics RNA-dependent RNA polymerase(RdRp) severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：