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The association between Tai Chi exercise and safe driving performance among older adults： An observational study

Journal of Sport and Health Science 2018年第1期7卷 83-94页

作者： sally miller Ruth E.Taylor-Piliae School of Nursing Vanderbilt University Nashville TN 37240 USA College of Nursing The University of Arizona Tucson AZ 85721 USA

Background: Age-related cognitive and physical decline can impair safe driving performance. Tai Chi exercise benefits cognitive and physical function and may influence safe driving performance in older adults. The primary aim of this observational study was to compare cognitive processes and physical function related to safe driving performance among older adult Tai Chi practitioners to normative reference *** aims were to examine relationships between Tai Chi exercise habits, cognitive processes, and physical function related to safe driving performance and to explore potential predictors of safe driving ***: The Driving Health Inventory, the Driving Scenes Test, other driving-related cognitive and physical measures, and self-reported measures including the Mindful Attention Awareness Scale(MAAS) and the Vitality Plus Scale(VPS) were collected from current Tai Chi practitioners(n = 58; age 72.9 ± 5.9 years, mean ± SD) with median >3 years Tai Chi ***: Compared to normative reference values, participants performed better on numerous cognitive measures including the Driving Scenes Test(p < 0.001, d = 1.63), maze navigation(p = 0.017, d = 0.27), the Useful Field of View Test(p < 0.001, r = 0.15), and on physical measures including the Rapid Walk Test(p < 0.001, r = 0.20), and the Right Foot Tapping Test,(p < 0.001, r = 0.35). Participants scored higher than normative reference values on MAAS and VPS(p < 0.001, d = 0.75; p = 0.002, d = 0.38, respectively). Statistically significant correlations were found between several study measures. The digit span backward test was the strongest predictor of safe driving performance(β = 0.34,p = 0.009).Conclusion: Tai Chi exercise has the potential to impact cognitive processes and physical function related to safe driving performance. Further study using randomized controlled trials, structured Tai Chi exercise doses, and driving simulator or on-road driving performance as outcome measures

关键词： Automobile driving Driving performance Exercise Older adults Physical activity Tai Chi

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谁在奏响生命的乐章?

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新东方英语（中学版） 2008年第Z2期 98-99页

作者： sally miller 周佳

林荫下,石缝间,池塘里,溪流中……一首首生命的乐章在缓缓谱就,谁又是那乐章中跳动着的音符?

关键词：池塘牛蛙溪流斑点孵化生命天鹅绒鳄龟食物水坑

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防治瓜类细菌性果斑病的小分子化合物筛选研究

防治瓜类细菌性果斑病的小分子化合物筛选研究

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中国植物病理学会2019年学术年会

作者：芦钰 Loic Deblais Gireesh Rajashekara sally A.miller 张海军吴萍徐秀兰北京市农林科学院蔬菜研究中心农业部华北地区园艺作物生物学与种质创制重点实验室农业部都市农业(北方)重点实验室 Food and Animal Health Research Program The Ohio State UniversityOhio Agricultural Research and Development Center Department of Plant Pathology The Ohio State UniversityOhio Agricultural Research and Development Center

西瓜嗜酸菌（Acidovorax citrulli）是引起瓜类细菌性果斑病的重要种传细菌,对瓜类作物生产造成巨大经济损失,种子处理是预防和控制果斑病的关键环节。本研究利用高通量小分子化合物筛选技术,对4个小分子化合物库共计4 952个小分子化合... 详细信息

西瓜嗜酸菌（Acidovorax citrulli）是引起瓜类细菌性果斑病的重要种传细菌,对瓜类作物生产造成巨大经济损失,种子处理是预防和控制果斑病的关键环节。本研究利用高通量小分子化合物筛选技术,对4个小分子化合物库共计4 952个小分子化合物进行靶标菌的生长抑制初步筛选。初次筛选小分子化合物浓度为100μmol/L,以***野生型菌株Xu 3-14为靶标,共筛选出具有致死和完全抑制效果的小分子化合物127个（选中率为2.5%）。二次筛选发现部分化合物在对番茄细菌性溃疡病菌（Clavibacter miciganensis ***）和十字花科黑腐病菌（Xanthomonas campestris ***）保持抑制作用的同时,对植物有益菌如荧光假单胞菌（Pseudomonas fluorescens）和枯草芽孢杆菌（Bacillus subtilis）的生长无显著影响。50%以上的化合物对拟南芥和西瓜没有表现植物毒性。综合分析二次筛选中小分子化合物的特异性、敏感性和植物毒性的评估结果,以及小分子化合物对***种子到种苗传带抑制率的实验室测试结果,选出了9个化合物作为种子处理药剂对人工接菌的西瓜、甜瓜种子进行田间测试。最终选出5个显著抑制***的小分子化合物,防病效果最高可达到95%。本研究筛选出的5种小分子化合物为***特异性杀菌剂的开发提供了参考。

关键词： Acidovorax citrulli 瓜类细菌性果斑病小分子化合物高通量筛选

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Associations of Gestational Exposure to Air Pollution and Polycyclic Aromatic Hydrocarbons with Placental Inflammation

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Environment & Health 2024年第9期2卷 672-680页

作者： Emily A.Craig Yan Lin Yihui Ge Xiangtian Wang Susan K.Murphy Donald K.Harrington Richard K.miller sally W.Thurston Philip K.Hopke Emily S.Barrett Thomas G.O’Connor David Q.Rich Junfeng Zhang Nicholas School of the Environment&Duke Global Health Institute Duke UniversityDurhamNorth Carolina 27708United States Department of Psychiatry University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Obstetrics and Gynecology University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Environmental Medicine and Department of Pediatrics University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Psychology University of RochesterRochesterNew York 14642United States Department of Biostatistics and Computational Biology and Department of Environmental Medicine University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Public Health Sciences University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Biostatistics and Epidemiology Rutgers School of Public HealthPiscatawayNew Jersey 08854United States Department of Psychiatry and Department of Neuroscience University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Public Health Sciences Department of Medicineand Department of Environmental MedicineUniversity of Rochester School of Medicine and DentistryRochesterNew York 14642United States

Restricted fetal growth(RFG)is a leading contributor to perinatal mortality and has been associated with gestational exposure to air pollution,such as fine particulate matter(PM_(2.5)),nitrogen dioxide(NO2),and polycyclic aromatic hydrocarbons(PAHs).This study examines the association between trimester-specific and weekly means of air pollution throughout gestation and placental inflammatory markers at *** a prospective cohort study of 263 pregnant women in Rochester,NY,we measured interleukin-6(IL-6)and tumor necrosis factor-alpha(TNF-α)in placental tissue and estimated gestational exposure to PM_(2.5)and NO_(2)using a high-resolution spatial-temporal *** to PAHs was estimated using urinary 1-hydroxypyrene(1-OHP)concentrations collected once per *** distributed lag models with a penalized spline function,each interquartile range(2.6μg/m^(3))increase in PM_(2.5)concentration during gestational weeks 6−11 was associated with decreased placental IL-6 levels(−22.2%,95%CI:−39.0%,−0.64%).Using multiple linear regression models,each interquartile range increase of 1-OHP was associated with an increase in TNF-αin the first trimester(58.5%,95%CI:20.7%,74.2%),third trimester(22.9%,95%CI:0.04%,49.5%),and entire pregnancy(29.6%,95%CI:3.9%,60.6%).Our results suggest gestational exposure to air pollution may alter the inflammatory environment of the placenta at delivery.

关键词： pregnancy air pollution PAHs placenta tumor necrosis factor interleukin

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