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Spotted Hyena Optimizer Driven Deep Learning-Based Drug-Drug Interaction Prediction in Big Data Environment

Computer Systems Science & Engineering 2023年第9期46卷 3831-3845页

作者： Mohammed Jasim Mohammed Jasim Shakir Fattah Kak Zainab salih Ageed Subhi R.M.Zeebaree Engineering College Al-Kitab UniversityKirkukIraq Information Technology Department Technical College of Informatics-AkreDuhok Polytechnic UniversityDuhokIraq Computer Science Department College of ScienceNawroz UniversityDuhokIraq Energy Engineering Department Technical College of EngineeringDuhok Polytechnic UniversityDuhokIraq

Nowadays,smart healthcare and biomedical research have marked a substantial growth rate in terms of their presence in the literature,computational approaches,and discoveries,owing to which a massive quantity of experimental datasets was published and generated(Big Data)for describing and validating such ***-drug interaction(DDI)significantly contributed to drug administration and *** continues as the main obstacle in offering inexpensive and safe *** normally happens for patients with extensive medication,leading them to take many drugs *** may cause side effects,either mild or severe health *** reduced victims’quality of life and increased hospital healthcare expenses by increasing their recovery *** efforts were made to formulate new methods for DDI prediction to overcome this *** this aspect,this study designs a new Spotted Hyena Optimizer Driven Deep Learning based Drug-Drug Interaction Prediction(SHODL-DDIP)model in a big data *** the presented SHODL-DDIP technique,the relativity and characteristics of the drugs can be identified from different sources for *** input data is preprocessed at the primary level to improve its ***,the salp swarm optimization algorithm(SSO)is used to select *** this study,the deep belief network(DBN)model is exploited to predict the DDI *** SHO algorithm is involved in improvising the DBN model’s predictive outcomes,showing the novelty of the *** experimental result analysis of the SHODL-DDIP technique is tested using drug databases,and the results signified the improvements of the SHODLDDIP technique over other recent models in terms of different performance measures.

关键词： Drug-drug interaction deep learning spotted hyena optimization feature selection classification

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Esophagogastric junction outflow obstruction: Where are we now in diagnosis and management?

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World Journal of Gastroenterology 2019年第4期25卷 411-416页

作者： salih Samo Emad Qayed Department of Medicine Division of Digestive Diseases Emory University School of Medicine

Esophagogastric junction outflow obstruction(EGJOO) is a major motility disorder based on the Chicago Classification of esophageal motility *** entity involves a heterogenous group of underlying etiologies. The diagnosis is reached by performing high-resolution manometry. This reveals evidence of obstruction at the esophagogastric junction, manifested by an elevated integrated relaxation pressure(IRP) above a cutoff value(IRP threshold varies by the manometric technology and catheter used), with preserved peristalsis. Further tests like endoscopy, timed barium esophagram, and cross-sectional imaging can help further elucidate the underlying etiology and rule out mechanical *** is tailored to the underlying cause. Similar to achalasia, treatment targeting lower esophageal sphincter disruption like pneumatic dilation, peroral endoscopic myotomy, and botulinum injection are used in patients with functional EGJOO and persistent symptoms.

关键词： Esophagogastric junction outflow obstruction High-resolution manometry

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Effect of Training Nurses in ICU in Immediate Care Post Cardiac Surgery

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World Journal of Cardiovascular Surgery 2023年第10期13卷 154-158页

作者： Fathia Saeed salih’s Mohamed Medical-Surgical Nursing Department National Ribat University Khartoum Sudan

The specialty of cardiovascular surgical nursing has advanced patient care significantly both before and after surgery, and it is now a well-established field. The primary goal of cardiovascular surgical nursing is to optimize the patient's recovery and prevent complications. Immediate nursing care for post-operative cardiac patients in a state of controlled shock due to fluid shift and varying vascular tone. Aim of the Study: Assessment of nurse’s knowledge and performance after the training program of nursing care immediately after a patient arrives from cardiac surgery. Methods: This pre and post-intervention study was conducted at cardiac centers in Sudan Alshaab and Ahmed Gasim Cardiac Center. The aim of the study was to evaluate the impact on nurses’ performance after training program post open-heart surgery. In the initial phase of the study, all 98 nurses working in the intensive care units at Alshaab and Ahmed Gasim cardiac centers were designated as the study group and evaluated before the intervention. Subsequently, the same group was reassessed after the intervention (phase 2), allowing for a comparison of the pre- and post-intervention results. The assessment involved the use of a specifically designed questionnaire and an observation checklist developed in accordance with the standards recommended by the American Nurses Association (phase 3). Result: Descriptive analysis was performed using the Chi-square test, the difference in the performance between the study group before intervention and after the intervention was assessed by the mean of chi-square significantly was taken as p < 0.05.

关键词： Effect Training Immediate Nursing Care Intensive Unit

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Synthesis and Characterization of New Macrocyclic Cu（Ⅱ） Complexes from Various Diamines, Copper（Ⅱ） Nitrate and 1,4-Bis（2-formylphenoxy）butane

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Chinese Journal of Chemistry 2007年第10期25卷 1547-1550页

作者： ILHAN, salih TEMEL, Hamdi KILIC, Ahmet Chemistry Department Faculty of Education Dicle University Diyarbakir 21010 Turkey Chemistry Department Faculty of Art and Science Harran University Sanhurfa 63100 Turkey

Six new macrocyclic complexes were synthesized by a template reaction of 1,4-bis（2-formylphenoxy）butane with diamines and Cu（NO3）2·3H2O and their structures were proposed on the basis of elemental analysis, FT-IR, UV-Vis, magnetic susceptibility measurements, molar conductivity measurements and mass spectra. The metal to ligand molar ratios of the Cu（Ⅱ） complexes were found to be 1 ： 1. The Cu（Ⅱ） complexes are 1 ： 2 electrolytes as shown by their molar conductivities （∧m） in DMF at 10^-3 mol·L^-1. Due to the existence of free ions the Cu（Ⅱ） complexes are electrically conductive. Their configurations were proposed to be probably distorted octahedral.

关键词： macrocyclic Schiff base complex 1,4-bis(2-formylphenoxy)butane diamine copper(Ⅱ) complex

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Analysis of temporal changes in land cover and landscape metrics of a managed forest in the west Black Sea region of northern Turkey: 1970–2010

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Journal of Forestry Research 2018年第1期29卷 139-150页

作者： Hayati Zengin Ahmet salih Degermenci Pete Bettinger Department of Forest Management and Planning Faculty of Forestry Duzce University Warnell School of Forestry and Natural Resources University of Georgia

Forest structure changes continuously by natural and anthropogenic effects. Because the level of goods and services provided by forest ecosystems are related to this structure, some attributes have to be controlled while they are being managed. In this paper we describe the long-term temporal changes in land area and landscape metrics related to different land uses of a managed forest in Turkey. The study was carried out for the Daday Forest Planning Unit located in the west Black Sea region of northern Turkey. The total area is 16,813 ha and besides wood production, it is managed for erosion control, public health, aesthetics, and recreation. Stand type maps that were constructed in 1970,1989, 1999, and 2010 were used in this analysis. Transition matrixes that illustrate area changes among cover types and temporal changes on some landscape metrics were obtained using Geographic Information Systems. Stands were separated into small patches, and thus the number of patches increased nearly two-fold between 1970 and 2010. The total forest edge increased and through the associated fragmentation, the amount of core forest area decreased at the landscape scale. Landscape metrics were applied to digitized versions of historical maps to assess how forest area changed. Human use of the land has changed, forest management practices have evolved, and these along with natural forest growth have contributed to interesting changes in landscape character.

关键词： Landscape metrics Land cover change Temporal change Turkey

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Global threshold dynamics of an age structured alcoholism model

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International Journal of Biomathematics 2021年第3期14卷 153-186页

作者： Soufiane Bentout salih Djilali Abdenasser Chekroun Laboratoire d'Analyse Non Linéaire et Mathématiques Appliquées University of TlemcenTlemcen 13000Algeria Department of Mathematics and Informatics Belhadj Bouchaib University Center of Ain TemouchentAin Temouchent 46OOOAlgeria Faculty of Exact and Computer Sciences Mathematic DepartmentHassiba Benbouali UniversityChiefAlgeria University of Abou Bekr Belkaid Tlemcen Tlemcen 13000Algeria

We consider in this research an age-structured alcoholism *** global behavior of the model is *** is proved that the system has a threshold dynamics in terms of the basic reproduction number(BRN),where we obtained that alcohol-free equilibrium(AFE)is globally asymptotically stable(GAS)in the case R_(0)≤1,but for R_(0)>1 we found that the system persists and the nontrivial equilibrium(EE)is ***,the effects of the susceptible drinkers rate and the repulse rate of the recovers to alcoholics are investigated,which allow us to provide a proper strategy for reducing the spread of alcohol use in the studied *** obtained mathematical results are tested numerically next to its biological relevance.

关键词： Mathematical biology age-structured partial differential equations alcohol model uniform persistence global behavior Lyapunov function

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Resource Exhaustion Attack Detection Scheme for WLAN Using Artificial Neural Network

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Computers, Materials & Continua 2023年第3期74卷 5607-5623页

作者： Abdallah Elhigazi Abdallah Mosab Hamdan Shukor Abd Razak Fuad A.Ghalib Muzaffar Hamzah Suleman Khan Siddiq Ahmed Babikir Ali Mutaz H.H.Khairi Sayeed salih Faculty of Engineering Future UniversityKhartoum 10553Sudan Faculty of Computing and Informatics Universiti Malaysia SabahKota Kinabalu88400Malaysia Information Assurance and Security Research School of ComputingUniversiti Teknologi MalaysiaJohor81310Malaysia School of Psychology and Computer Science University of Central LancashirePreston PR12HEUK Deaptement of Management Information Systems College of Administrative ScienceApplied Science UniversityAl Eker623Bahrain Deaptement of Information Technology College of Computer and Information SciencesKing Saud UniversityRiyadh11461Saudi Arabia

IEEE 802.11 Wi-Fi networks are prone to many denial of service(DoS)attacks due to vulnerabilities at the media access control(MAC)layer of the 802.11 *** to the data transmission nature of the wireless local area network(WLAN)through radio waves,its communication is exposed to the possibility of being attacked by illegitimate ***,the security design of the wireless structure is vulnerable to versatile *** example,the attacker can imitate genuine features,rendering classificationbased methods inaccurate in differentiating between real and false *** security standards have been proposed over the last decades to overcome many wireless network attacks,effectively detecting such attacks is crucial in today’s real-world *** paper presents a novel resource exhaustion attack detection scheme(READS)to detect resource exhaustion attacks *** proposed scheme can differentiate between the genuine and fake management frames in the early stages of the attack such that access points can effectively mitigate the consequences of the *** scheme is built through learning from clustered samples using artificial neural networks to identify the genuine and rogue resource exhaustion management frames effectively and efficiently in *** proposed scheme consists of four modules whichmake it capable to alleviates the attack impact more effectively than the related *** experimental results show the effectiveness of the proposed technique by gaining an 89.11%improvement compared to the existing works in terms of detection.

关键词： 802.11 media access control(MAC) wireless local area network(WLAN) artificial neural network denial-of-service(DoS)

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Clinical presentation, diagnosis and treatment of vulvovaginitis in girls: a current approach and review of the literature

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World Journal of Pediatrics 2017年第2期13卷 101-105页

作者： (I)lke Beyitler salih Kavukcu Department of Pediatrics Near East University HospitalNicosiaNorth Cyprus Department of Pediatrics Division of NephrologyNear East University HospitalNicosiaNorth Cyprus

Background:Vulvovaginitis is the most common cause of gynecological complaints in children and young *** of the factors which cause vulvovaginitis include hypoestrogenism,the anatomical proximity of rectum and delicate vulvar skin and vaginal *** sources:We made a literature search with Pubmed,Medline and Cochrane database from January 2002 to May 2015 in English language using the key words vulvovaginitis,children,clinical,diagnosis and ***:Vulvovaginitis in girls is usually caused by non-specific factors and hygiene measures,bioyoghurt and avoidance of chemical irritants are generally *** control if necessary and prevention of voiding dysfunction are *** flora is important in girls and results should be interpreted with clinical features to decide whether an isolated microorganism is part of the normal microflora or is the cause of symptomatic *** treatment is generally considered in case of a detected pathogen *** of a sexually transmitted organism requires further *** disease may not always indicate a foreign body but it must be taken into *** and parents are encouraged psychologically in all steps of evaluation,diagnosis and ***,nanotechnology and petroleum jelly are other important treatment options used in ***:In this review,we present current approach to the presentation and management of vulvovaginitis in *** disorder requires a comprehensive evaluation in all steps of diagnosis,differential diagnosis and treatment.

关键词： children diagnosis treatment vulvovaginitis

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Backward,Hopf bifurcation in a heroin epidemic model with treat age

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International Journal of Modeling, Simulation, and Scientific Computing 2021年第2期12卷 198-222页

作者： Soufiane Bentout salih Djilali Behzad Ghanbari Laboratoire d’Analyse Non Lin´eaire et Math´ematiques Appliqu´ees Universit´e de Tlemcen TlemcenAlgeria Department of Basic Science Kermanshah University of Technology KermanshahIran Faculty of Exact and Computer Sciences Mathematic Department Hassiba Benbouali UniversityChlefAlgeria §Department of Mathematics and Informatics Belhadj Bouchaib University Center of Ain Temouchent BP 284 RP 46000Algeria

Heroin is considered as damage on the health of the *** this paper,we consider a heroin epidemic model with treat age,where the inner rivalry in between the drug users for a small dose of drugs is *** influence of treatment period for a drug consumer before quitting treatment is investigated,where it is obtained that the considered model can undergo backward bifurcation,which shows the possibility of having two endemic equilibriums,this type of bifurcation is discussed in terms of the basic reproduction number *** bifurcation diagram is drown in the case of an age structured ***,we show the existence of Hopf bifurcation is shown under suitable conditions on the model *** obtained mathematical results are confirmed numerically.

关键词： Backward bifurcation heroin epidemic age-structured model Hopfbifurcation

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不对称故障下的LCC-HVDC系统连续换相失败抑制策略研究

不对称故障下的LCC-HVDC系统连续换相失败抑制策略研究

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作者： Ahmed Omer salih 山东大学

学位级别：硕士

高压直流输电是一种成熟的技术,主要用于远距离传输大容量电力,连接异步网络或海底电缆系统。由于其与现有系统的互连和新技术的应用,电力系统的复杂性逐渐增加,同时,许多经济和其他限制因素迫使电力公司在最大稳定性极限附近运行其系统... 详细信息

高压直流输电是一种成熟的技术,主要用于远距离传输大容量电力,连接异步网络或海底电缆系统。由于其与现有系统的互连和新技术的应用,电力系统的复杂性逐渐增加,同时,许多经济和其他限制因素迫使电力公司在最大稳定性极限附近运行其系统,并以最低的成本提供可靠和清洁的电力[1]。电力需求的持续增长迫使需要远距离、大容量的高压直流系统进行电力传输。此外,人们越来越有兴趣将可再生能源纳入电网,再次依赖高压直流输电链路。因此,高压直流输电技术的应用是克服这些问题的必要手段。基于线路换相换流器的高压直流（LCC-HVDC）已经证明了它们在远距离传输大容量电力方面的有效性。LCC-HVDC的主要缺点之一是换相故障发生的风险很高。换相故障主要发生在逆变器侧,由于交流系统干扰或控制故障。当发生换向失败故障时,可能会威胁到系统的稳定性,因为它会导致传输功率的扰动冲击。此外,它还会增加逆变器的无功功耗,这在弱交流系统的情况下是不可取的。为了限制换相失败的影响,提出了几种方法。无论是在改进一次设备方面,还是在改进控制系统方面。改进控制系统是采用最多的,因为它具有可行性,并且可靠性高。在通过改进控制系统来预防换相故障时,有两种主要方法可用于提高系统性能,无论是通过修改触发角,还是使用单独的控制系统来控制熄弧角。但是,为了能够制定有效的预防策略,应充分利用控制系统,以避免应用预防策略和增加系统的无功功率,这是不希望的。尽管不对称故障是换相失败的主要原因[1],但迄今为止,用于分析和预防LCC-HVDC换相故障的模型并没有准确地解决相位移问题,无论是在检测策略方面还是在换流阀级控制下发出触发角。这将限制对换相失败故障的检测和预防。在本论文中,提出了有效的策略来有效地检测和防止换相故障。本论文的贡献可以总结如下:（1）提出一个准确的模型:在不对称故障期间,系统将发生相位移。在本论文中,开发了一个基于序分量的模型,以获取系统上可能发生的不同相位移。相位移尤其会影响系统的触发脉冲。如果在晶闸管不正向偏置时施加触发脉冲,则会发生换相故障。因此,需要随时检测系统的相位角,以有效地控制系统。（2）提出强化策略:基于提出的精确模型,开发有效利用控制系统的有效方法。为了提高PLL的性能,并能够在晶闸管正向偏置时提供触发脉冲,使用提出的数学模型提供电压,并使用基于Tan-Sun的PLL来提供触发脉冲。通过使用这种方法,即使故障持续一段时间,也可以有效地防止连续换相失败故障,而无需增加换相面积。为了验证所提出的抑制换相失败的方法,使用PSCAD/EMTDC进行了仿真。在逆变器终端施加不同类型的故障,以研究系统性能。故障电感在较大的范围内变化,以验证所提出的方法。此外,还考虑了不同强度的系统,以确保该方法在不同条件下的有效运行。

关键词：换相失败不对称故障换相失败的预防序分量 Tan-Sun坐标变换

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