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Myasthenic crisis-induced Takotsubo cardiomyopathy in an elderly man:A case report of an underestimated but deadly combination

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World Journal of Cardiology 2021年第1期13卷 21-27页

作者： Yvonne Kuo Thomas H Ottens Ivo van der Bilt Ruud WM Keunen sakir akin Intensive Care Unit HagaziekenhuisThe Hague 2545Netherlands Department of Cardiology HagaziekenhuisThe Hague 2545Netherlands Department of Neurology Haga Teaching HospitalThe Hague 2545Netherlands

BACKGROUND Patients with myasthenia gravis(MG)are at a higher risk of developing Takotsubo cardiomyopathy(TTC),particularly during a myasthenic *** crisis-associated TTC occurs predominantly in *** this case report,we present a man with metastasized prostate carcinoma who developed TTC after new-onset *** SUMMARY An 81-year-old man with non-insulin dependent diabetes mellitus and metastasized prostate carcinoma presented with *** primary assessment examination at the emergency department,there was evident blepharoptosis of his right *** electrocardiograms were suggestive of an acute anterior wall myocardial infarction,for which he underwent emergency coronary *** obstructive coronary artery disease was *** the coronary angiography,the patient developed respiratory failure and was admitted to the Intensive Care Unit for non-invasive respiratory *** following day,diagnostic neostigmine test revealed a myasthenic *** echocardiography revealed left ventricular apical ballooning with a typical appearance of *** the potentially reversible character of both MG and TTC,the patient and family requested an end of support in the Intensive Care Unit due to age and chronic malignancy with reduced quality of life in recent months after non-chemo-responding prostate *** patient died soon after treatment *** Elderly men should be carefully evaluated for TTC when new-onset MG is diagnosed.

关键词： Takotsubo cardiomyopathy Broken heart syndrome Stress-induced cardiomyopathy Myasthenic crisis Respiratory failure Case report

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