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Journal of Geographic Information System 2015年第4期7卷 438-447页

作者： Kashif Aslam sajid Rashid Rashid Saleem Rana Muhammad Sohail Aslam Institute of Geology University of the Punjab Lahore Pakistan Pakistan Water and Power Development Authority Lahore Pakistan

Agriculture is being main stay of Pakistan economy and it’s very significant to monitor the existing agricultural areas and its changes, due to different aspects like salinity and waterlogging, which reduce the fertility of agricultural lands adversely. Managing salinity so as to minimize its environmental impact is a prerequisite for the long-term sustainability of irrigated agriculture. It is ironic that the irrigated areas are those that are afflicted most by the twin menaces of waterlogging and salinity. Geospatial technology was used to assess the waterlogging and salinity condition in Nara canal command area, during the last two surveys conducted in years 1977-1981 and 2001- 2003 respectively. After analyzing the results in detail, we obtain a clear relationship among salt affected soils, and waterlogged areas reveal that 0.2% to 1.25% of salt affected areas fall under the shallow zone with high water table. The spatial distribution of water table shows various trends among the water tables, and the surface salinity of surface saline areas has been increased due to waterlogging caused by unmanaged spatial drainage system.

关键词： Geospatial Salinity Waterlogging Nara Canal and Sindh in Pakistan

Riverine Flood Damage Assessment of Cultivated Lands along Chenab River Using GIS and Remotely Sensed Data: A Case Study of District Hafizabad, Punjab, Pakistan

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Journal of Geographic Information System 2015年第5期7卷 506-526页

作者： Khurram Chohan sajid Rashid Ahmad Zia ul Islam Muhammad Adrees The Institute of Geology University of the Punjab Lahore Pakistan The Urban Unit Urban Sector Planning and Management Services Unit (Pvt.) Ltd. Lahore Pakistan

Flood is one of a kind of disasters which harms human and animal life around the globe. Pakistan has been observing massive floods for many years because of daily and seasonal variation in the temperature levels. Wheat, rice, sugarcane and cotton are major crops cultivated in Punjab region of Pakistan in which rice and sugarcane are mostly effected by floods. In this research paper, damage assessment of cultivated land in district Hafizabad along Chenab River has been calculated. Supervised Classification and Soil Adjusted Vegetation Index (SAVI) methods are applied. Pre-flood 2014, post-flood 2014, and pre-flood 2015 Landsat 8 images have been used to calculate the extent of damages to cultivated lands. Water, sand, silt, bare soil and vegetation are classified to identify damage. Results show that vegetation cover has plummeted to 50% after the arrival of flood 2014 in the Chenab. Similarly, 6.7047% of sand and 15.7339% of bare soil deposits have surfaced which have not yet been removed from fertile lands in 2015. 18.4376% standing crop damage has been analyzed under this study. 14.0245% silt deposits have been calculated as post-flood effects. 46.4260% land has been cultivated in 2015 which is 15.5024% lower than 2014 cultivated land. Furthermore, field verification survey has given promising results and has a great correlation with satellite based recovery results.

关键词： Flood SAVI Supervised Classification GIS Remote Sensing Damage Assessment Sand

GIS Enabled Condition Based Asset Management of Gas Distribution Network: A Case Study of Shahdara, Lahore Pakistan

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Journal of Geographic Information System 2015年第4期7卷 358-368页

作者： Zia Ul Islam sajid Rashid Ahmad Khurram Chohan Ather Ashraf Institute of Geology University of the Punjab Lahore Pakistan Punjab University College of Information Technology (PUCIT) University of the Punjab Lahore Pakistan

World energy consumption increased by 56 percent, from 524 quadrillion Btu in 2010 to 820 quadrillion Btu in 2040. The increased demand in energy consumption is fulfilled by different renewable and non-renewable sources such as petroleum, natural gas, electricity, nuclear etc. Natural gas is one of the most important sources of energy. SNGPL has been managing a 94,263 km long gas pipelines network covering approximately the northern part of Pakistan. In this paper we have presented the use of condition based maintenance (CBM) management techniques with a?geographical information system (GIS) for asset management of a gas distribution network of?SNGPL. The continuous monitoring and updating of asset data reveal where the assets are located and which needs maintenance or which lies in critical condition. The system helps to save time and reduce visits to the sites and labour reduction.

关键词： Asset Management Distribution Pipeline Network GIS

Joint effect of pre-operative anemia and perioperative blood transfusion on outcomes of colon-cancer patients undergoing colectomy

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Gastroenterology Report 2020年第2期8卷 151-157,I0003页

作者： Zheng Liu Jia-Jun Luo Kevin Y.Pei sajid A.Khan Xiao-Xu Wang Zhi-Xun Zhao Ming Yang Caroline H.Johnson Xi-Shan Wang Yawei Zhang Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Surgery Yale School of MedicineNew HavenCTUSA Department of Surgery School of MedicineTexas Tech University Health Sciences CenterLubbockTXUSA Department of Environmental Health Sciences Yale School of Public HealthNew HavenCTUSA

Background:Both pre-operative anemia and perioperative(intra-and/or post-operative)blood transfusion have been reported to increase post-operative complications in patients with colon cancer undergoing ***,their joint effect has not been *** purpose of this study was to evaluate the joint effect of pre-operative anemia and perioperative blood transfusion on the post-operative outcome of colon-cancer patients after ***:We identified patients from the American College of Surgeons National Surgical Quality Improvement Program(NSQIP)database 2006–2016 who underwent colectomy for colon *** logistic regression analysis was employed to assess the independent and joint effects of anemia and blood transfusion on patient ***:A total of 35,863 patients—18,936(52.8%)with left-side colon cancer(LCC)and 16,927(47.2%)with right-side colon cancer(RCC)—were *** patients were more likely to have mild anemia(62.7%)and severe anemia(2.9%)than LCC patients(40.2%mild anemia and 1.4%severe anemia).A total of 2,661(7.4%)of all patients(1,079[5.7%]with LCC and 1,582[9.3%]with RCC)received a perioperative blood ***,the occurrence rates of complications were comparable between LCC and RCC patients(odds ratio[OR]=1.01;95%confidence interval[CI]=0.95–1.07;P=0.750).There were significant joint effects of anemia and transfusion on complications and the 30-day death rate(P for interaction:0.010).Patients without anemia who received a transfusion had a higher risk of any complications(LCC,OR=3.51;95%CI=2.55–4.85;P<0.001;RCC,OR=3.74;95%CI=2.50–5.59;P<0.001),minor complications(LCC,OR=2.54;95%CI=1.63–3.97;P<0.001;RCC,OR=2.27;95%CI=1.24–4.15;P=0.008),and major complications(LCC,OR=5.31;95%CI=3.68–7.64;P<0.001;RCC,OR=5.64;95%CI=3.61–8.79;P<0.001),and had an increased 30-day death rate(LCC,OR=6.97;95%CI=3.07–15.80;P<0.001;RCC,OR=4.91;95%CI=1.88–12.85;P=0.001)than patients without anemia who did not receive a

关键词： colon cancer colectomy anemia blood transfusion

Evaluation of antihepatotoxic potential of Solanum xanthocarpum fruit extract against antitubercular drugs induced hepatopathy in experimental rodents

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Asian Pacific Journal of Tropical Biomedicine 2012年第6期2卷 454-460页

作者： Talib Hussain Ramesh K Gupta Sweety K Mohd sajid Khan Md Sarfaraj Hussain Md Arif Arshad Hussain Md Faiyazuddin Chandana Venkateswara Rao Pharmacognosy and Ethnopharmacology Division National Botanical Research Institute Department of Pharmacology and Toxicology Faculty of Pharmacy Integral University Department of Pharmacology Royal College of Pharmacy and Health Sciences Department of Biotechnology Integral University

Objective:To assess the hepatoprotective effect of Solanum xanthocarpum(S. xanthocarpum) fruit extract against antitubercular drug-induced liver toxicity in experimental ***:Ethanolic(50%) fruit extract ofS. xanthocarpum(100, 200 and 400 mg/kg bw) was administered daily for 35 days in experimental animals. Liver toxicity was induced by combination of three antitubercular drugs [isoniazid(I) 7.5 mg/kg, rifampicin(R) 10 mg/kg and pyrazinamide(P) 35 mg/kg] given orally as suspension for 35 days in rats. The hepatoprotective activity was assessed using various biochemical parameters like aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phosphatise(ALP), total bilirubin(TBL), albumin(ALB), total protein(TP), lactate dehydroginase(LDH), and serum cholesterol(CHL). Meanwhile,in vivoantioxidant activities as lipid peroxidation(LPO), reduced glutathione(GSH), superoxide dismutase(SOD) and catalase(CAT) were measured in rat liver homogenate. The biochemical observations were supplemented by histopathological ***:The results demonstrated that treatment ***(P<0.05-P<0.001) and dose-dependently prevented drug induced increase in serum levels of hepatic enzymes. Furthermore,S. xanthocarpumsignificantly(up toP<0.001) reduced the LPO in the liver tissue and restored activities of defence antioxidant enzymes GSH, SOD and CAT towards normal levels. Histopathology of the liver tissue showed that S. xanthocarpumattenuated the hepatocellular necrosis and led to reduction in inflammatory cells ***:The results of this study strongly indicate the protective effect of S. xanthocarpumagainst liver injury which may be attributed to its hepatoprotective activity, and thereby scientifically support its traditional use.

关键词： Solanum xanthocarpum Rifampicin Isoniazid Pyrazinamide Antioxidant Antihepatotoxicity Hepatoprotective effect Antitubercular drug Liver toxicity Liver injury Biochemical parameter Histopathology

Mapping quantitative trait loci associated with starch paste viscosity attributes by using double haploid populations of rice (Oryza sativa L.)

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Journal of Integrative Agriculture 2020年第7期19卷 1691-1703页

作者： Tahmina SHAR SHENG Zhong-hua Umed ALI sajid FIAZ WEI Xiang-jin XIE Li-hong JIAO Gui-ai Fahad ALI SHAO Gao-neng HU Shi-kai HU Pei-song TANG Shao-qing State Key Laboratory of Rice Biology/Key Laboratory of Rice Biology and Breeding Ministry of Agriculture/China National Rice Research InstituteHangzhou 310006P.R.China

The paste viscosity attributes of starch,measured by rapid visco analyzer(RVA),are important factors for the evaluation of the cooking and eating qualities of rice in breeding *** determine the genetic roots of the paste viscosity attributes of rice grains,quantitative trait loci(QTLs)associated with the paste viscosity attributes were mapped,using a double haploid(DH)population derived from Zhongjiazao 17(YK17),a super rice variety,crossed with D50,a tropic japonica ***-four QTLs,for seven parameters of the RVA profiles,were identified in three planting *** 54 QTLs were located on all of the 12 chromosomes,with a single QTL explaining 5.99 to 47.11%of phenotypic *** the QTLs identified,four were repeatedly detected under three environmental conditions and the other four QTLs were repeated under two *** of the QTLs detected for peak viscosity(PKV),trough viscosity(TV),cool paste viscosity(CPV),breakdown viscosity(BDV),setback viscosity(SBV),and peak time(PeT)were located in the interval of RM 6775-RM 3805 under all three environmental conditions,with the exception of pasting temperature(PaT).For digenic interactions,eight QTLs with six traits were identified for additivexenvironment interactions in all three planting *** epistatic interactions were estimated only for PKV,SBV and *** present study will facilitate further understanding of the genetic architecture of eating and cooking quality(ECQ)in the rice quality improvement program.

关键词： RVA profiles eating and cooking quality(ECQ) quantitative trait loci(QTL) DH population rice

Gunshot injury to spine:An institutional experience of management and complications from a developing country

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Chinese Journal of Traumatology 2020年第6期23卷 324-328页

作者： Mir Ibrahim sajid Bushra Ahmad Shaikh Danish Mahmood Aneela Darbar Medical College Aga Khan UniversityKarachi74880Pakistan Department of Neurosurgery Aga Khan University HospitalKarachi74880Pakistan

Purpose Gunshot wounds are the second leading cause of spinal cord *** intervention for gunshot injury to the spine carries a high rate of *** is a scarcity of data on civilian gunshot injuries to the spine in *** 60 cases over the last 10 years have been recoded,with unusual presentation and neurological *** it is imperative to fill this gap in data,by reviewing cases of civilian gunshot injuries to spine presenting at a tertiary care hospital(Aga Khan University Hospital,Karachi).Methods This is a retrospective cohort *** of all ages who presented to the emergency department of Aga Khan University Hospital,with gunshot injuries to spine between January 2005 and December 2016 were included in the *** were collected on neurological status(American Spinal Injury Association score was used for the initial and follow-up neurological assessment),extent of cord transection,motor and sensory *** patients were further grouped into those with cord transection,and those with fractures of the bony spine but an intact spinal *** patients were then followed and the outcomes were *** A total of 40 patients were *** mean±SD of patients age was(30.9±9.5)*** the 40 patients with gunshot wounds,31 had the medical imaging performed at the facility,and hence they were included in this *** remaining 9 patients were excluded from this additional *** patients were managed surgically and 27 patients underwent the conservative *** mean±SD of follow-up was(8.7±7.2)*** our study,the thoracic spine was the most commonly injured region in gunshot *** the 31 patients with medical imaging performed at our institute,17(54.8%)had cord transection,of whom 8(47%)ultimately developed *** The prognosis of gunshot injuries to the spine can be varied depending on whether the spinal cord is intact or ***

关键词： Hospital management Cord transection Prognostic predictors Gunshot injury Spinal trauma

Predictability of Surgical Apgar Score for postoperative outcomes in hip fractures: A prospective observational study

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Journal of Acute Disease 2021年第1期10卷 8-11页

作者： Farhan Haroon sajid Younus Asif Peracha Nouman Memon Naveed Memon Department of Orthopaedic Surgery Liaquat National Hospital and Medical CollegeKarachiPakistan

Objective:To assess the utility and validation of the Surgical Apgar Score(SAS)in predicting postoperative complications of hip ***:This prospective observational study included patients who received operations for hip fractures from 1st March 2017 to 30th June 2018 at the Department of Orthopedic Surgery,Liaquat National Hospital and Medical *** were followed at the outpatient department,and complications and mortality were recorded through phone *** predictability of SAS for postoperative complications was ***:SAS≤4 was found as a significant predictor for postoperative pulmonary(P=0.008)and cardiac complications(P=0.042)as well as blood transfusion required to optimize postoperative hemoglobin(P=0.03)in the patients with hip ***:SAS provides reliable feedback information about patients'postoperative risk during the *** fracture patients with scores≤4 should be monitored for major complications both during the hospital admission and after the discharge.

关键词： Hip fractures Surgical Apgar Score Postoperative outcomes

Role of Polyamines in Ozone Exposed Ischemic-Reperfused Hearts

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American Journal of Analytical Chemistry 2011年第7期2卷 832-839页

作者： Rajat Sethi Sai Raghuveer Chava sajid Bashir Mauro E. Castro 不详

The effect of chronic ozone exposure to ischemia reperfusion (I/R) injury in isolated perfused rat hearts was previously demonstrated. The present study tested our hypothesis that chronic ozone exposure led to attenuation of polyamines in the heart, which may limit sensitivity to I/R. Sprague Dawley rats were continuously exposed for 8 hrs/day for 28 days to filtered air or 0.8 ppm ozone. Isolated hearts were previously subjected to 0.5 hour of global ischemia followed by 1 hour of reperfusion after which global polyamine content was examined between the two groups. Spermidine production was significantly increased in the experimental group compared to control group (of I/R hearts). These results suggest that ozone-induced sensitivity to chronic I/R injury activates myocardial polyamine stress response characterized by increased enzymatic activities and accumulation of spermidine. Collectively, these results suggest that I/R possibly disturbs polyamine metabolism, and increased oxidative stress and concomitant reduced myocardial cell viability.

关键词： Environmental Pollutants Cardiovascular Disease Polyamines Ischemia-Reperfusion (I/R) Injury Oxidative Stress

Risk Factors Associated with Birth Asphyxia in Rural District Matiari, Pakistan: A Case Control Study

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International Journal of Clinical Medicine 2014年第21期5卷 1430-1441页

作者： Farhana Tabassum Arjumand Rizvi Shabina Ariff sajid Soofi Zulfiqar A. Bhutta Department of Pediatrics and Child Health Aga Khan University Karachi Pakistan

Background: During the past two decades there has been a sustained decline in child mortality;however, neonatal mortality has remained stagnant. Each year approximately 4 million babies are born asphyxiated resulting in 2 million neonatal deaths and intrapartum stillbirths. Almost all neonatal deaths occur in developing countries, where the majority is delivered at homes with negligible antenatal care and poor perinatal services. Objectives: To identify socio-demographic and clinical risk factors associated with birth asphyxia in Matiari District of Sindh Province, Pakistan. Method: A matched case control study was conducted in Matiari District with 246 cases and 492 controls. Newborn deaths with birth asphyxia diagnosed through verbal autopsy accreditation during 2005 and 2006 were taken as cases. Controls were the live births during the same period, matched on area of residence, gender and age. Result: The factors found to be associated with birth asphyxia mortality in Matiari District of Sindh Province, Pakistan are maternal education, history of stillbirths, pregnancy complications (including smelly or excessive vaginal discharge and anemia), intrapartum complications (including fever, prolong or difficult labour, breech delivery, cord around child’s neck, premature delivery, large baby size) and failure to establish spontaneous respiration after birth. Conclusion and Recommendation: There is an immediate need to develop strategies for early identification and management of factors associated with birth asphyxia by involving women, families, communities, community health workers, health professionals and policy makers. Community health workers should be trained for emergency obstetric care, basic newborn care including preliminary resuscitation measures to provide skilled birth attendance and encourage early recognition and referral.

关键词： Birth Asphyxia Prolong Labor Antenatal Care