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7例菊形团形成型胶质神经元肿瘤(RGNT)病例的影像特征

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国际医学放射学杂志 2016年第2期 208-208页

作者： G.Medhi C.Prasad J.saini H.Pendharkar M.D.Bhat P.Pandey 任冬晴 Department of Neuroimaging and Interventional Radiology National Institute of Mental Health and Neurosciences

摘要目的菊形团形成型胶质神经元肿瘤(RGNT)是近年来报道的、罕见的胶质神经元肿瘤家族的特殊类型肿瘤。描述7例RGNT的影像特征(CT,MRI)。方法回顾性研究7例在研究所诊断和治疗的RGNT病人,包括男4例,女3例,年龄7～42岁,平均25岁,在3 T和... 详细信息

摘要目的菊形团形成型胶质神经元肿瘤(RGNT)是近年来报道的、罕见的胶质神经元肿瘤家族的特殊类型肿瘤。描述7例RGNT的影像特征(CT,MRI)。方法回顾性研究7例在研究所诊断和治疗的RGNT病人,包括男4例,女3例,年龄7～42岁,平均25岁,在3 T和1.5 T MR设备上进行扫描,所有病例均由2位经验丰富的神经放射学专家进行阅片并对影像结果进行汇总。结果 7例RGNT中有5例位于后颅窝,2例位于松果体区。其中1例表现为多发卫星样病灶,

关键词：胶质神经元肿瘤菊形团 RGNT 影像特征病例

内侧活动平台膝单髁置换术后衬垫脱位原因分析及治疗措施

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中华骨与关节外科杂志 2023年第3期16卷 219-225页

作者：齐新宇黎嘉澔李宜金陈锦伦叶鹏程曾建春冯文俊周赛妮庞智晖唐立明王海彬曾意荣广州中医药大学第一附属医院骨科广州510405 广州中医药大学广州510405

目的:分析内侧活动平台膝单髁置换术(UKA)后衬垫脱位原因,探讨其治疗措施。方法:回顾性分析2012年8月至2022年8月接受内侧活动平台UKA共723例745膝。观察术后衬垫脱位发生的时间和诱因,分析其发生原因并探讨其治疗措施。结果:745膝随访8... 详细信息

目的:分析内侧活动平台膝单髁置换术(UKA)后衬垫脱位原因,探讨其治疗措施。方法:回顾性分析2012年8月至2022年8月接受内侧活动平台UKA共723例745膝。观察术后衬垫脱位发生的时间和诱因,分析其发生原因并探讨其治疗措施。结果:745膝随访8~121个月,平均随访时间(52.4±24.1)个月。共9例10膝术后发生衬垫脱位,术后衬垫脱位率为1.34%(10/745),发生脱位时间为术后1~61个月,平均为术后(22.0±19.4)个月,其中约30%的衬垫脱位发生在术后半年之内,50%发生在术后1年之内。术后衬垫脱位诱因:2膝有明确外伤病史,3膝为下蹲站起或过度屈曲后发生,1膝为侧躺后发生,4膝无明显诱因。翻修术中探查发现:4膝发生内侧副韧带或关节囊松弛,3膝出现假体位置安装不良,1膝出现衬垫磨损,1膝衬垫与骨赘撞击,1膝无明确原因导致脱位。5膝采用全膝关节置换术进行翻修,2膝更换新的原厚度衬垫,2膝更换加厚衬垫并同时进行了关节囊紧缩术或内侧副韧带锚钉固定,1膝患者在外院更换加厚衬垫后再次发生脱位,最终接受全膝关节置换术进行翻修。结论:内侧活动平台UKA术后衬垫脱位率较低。术后衬垫脱位主要与术中内侧副韧带损伤、假体位置安装不良、衬垫撞击、衬垫磨损等有关。治疗方法包括麻醉下手法复位、更换新的衬垫、更换为固定衬垫、采用全膝关节置换术进行翻修等,应针对引起脱位的具体原因进行治疗。

关键词：膝单髁置换术活动平台假体衬垫脱位治疗

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海洋真菌Westerdykella dispersa FS350次级代谢产物的分离纯化与鉴定

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广东药科大学学报 2018年第2期34卷 132-136页

作者：许建林刘洪新陈玉婵李赛妮郭珩李浩华章卫民高晓霞广东药科大学药学院广东广州510006 广东省微生物研究所/省部共建华南应用微生物国家重点实验室/广东省菌种保藏与应用重点实验室/广东省微生物应用新技术公共实验室广东广州510070

目的研究海洋真菌Westerdykella dispersa FS350的次级代谢产物。方法利用正相硅胶柱、反相硅胶柱、凝胶柱和高效液相色谱等多种色谱方法对菌株FS350的液体发酵产物进行分离纯化,采用NMR、MS等波谱方法鉴定化合物结构,采用SRB法和DPPH... 详细信息

目的研究海洋真菌Westerdykella dispersa FS350的次级代谢产物。方法利用正相硅胶柱、反相硅胶柱、凝胶柱和高效液相色谱等多种色谱方法对菌株FS350的液体发酵产物进行分离纯化,采用NMR、MS等波谱方法鉴定化合物结构,采用SRB法和DPPH法测定化合物的生物活性。结果从发酵产物中分离得到了8个成分,分别鉴定为:2-(4-羟苯基)乙酸乙酯(1)、3-hydroxy-1-(2,6-dihydroxyphenyl)butan-1-one(2)、4-epiradicinol(3)、2-糠酸(4)、2-(4-羟苯基)-乙醇(5)、对羟基苯乙醇α-羟基丙酸酯(6)、(R)-甲羟戊酸内酯(7)和asterric acid(8)。结论化合物1~8均是首次从Westerdykella属真菌中分离得到,这些化合物均无明显的细胞毒和抗氧化活性。

关键词：海洋真菌 Westerdykella dispersa 次级代谢产物分离纯化鉴定

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Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,pssions in this *** There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid