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Investigation of factors affecting rural drinking water consumption using intelligent hybrid models

Water Science and Engineering 2023年第2期16卷 175-183页

作者： Alireza Mehrabani Bashar Hamed Nozari safar marofi Mohamad Mohamadi Ahad Ahadiiman Department of Water Science and Engineering Faculty of AgricultureBu-Ali Sina UniversityHamedan 65178-38695Iran University of Kurdistan Sanandaj 66177-15175Iran Sustainable Development Office of Hamedan Water and Wastewater Company Hamedan 65159-14478Iran

Identifying the factors affecting drinking water consumption is essential to the rational management of water resources and effective environment protection. In this study, the effects of the factors on rural drinking water demand were studied using the adaptive neuro-fuzzy inference system (ANFIS) and hybrid models, such as the ANFIS-genetic algorithm (GA), ANFIS-particle swarm optimization (PSO), and support vector machine (SVM)-simulated annealing (SA). The rural areas of Hamadan Province in Iran were selected for the case study. Five drinking water consumption factors were selected for the assessment according to the literature, data availability, and the characteristics of the study area (such as precipitation, relative humidity, temperature, the number of subscribers, and water price). The results showed that the standard errors of ANFIS, ANFIS-GA, ANFIS-PSO, and SVM-SA were 0.669, 0.619, 0.705, and 0.578, respectively. Therefore, the hybrid model SVM-SA outperformed other models. The sensitivity analysis showed that of the parameters affecting drinking water consumption, the number of subscribers significantly affected the water consumption rate, while the average temperature was the least significant factor. Water price was a factor that could be easily controlled, but it was always one of the least effective parameters due to the low water fee.

关键词： ANFIS Water distribution network Simulated annealing algorithm Support vector machine Adaptive neuro-fuzzy inference system

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Geometric investigation of entrance proportions of houses from the Qajar to the beginning of the early Pahlavi in Dezful City(1789—1979)

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Frontiers of Architectural Research 2024年第1期13卷 57-78页

作者： Raziyeh Rezadoost Dezfuli Mohammad Mehrakizadeh Behnaz safar Ali Najar Hassan Bazazzadeh Mohammadjavad Mahdavinejad Department of Architecture Poznan University of Technology61-131 PoznanPoland Department of Architecture and Urban Planning Jundi Shapur University of TechnologyDezfulIran College of Engineering and Architecture University of Nizwa616 Birkat Al MawzOman Department of Architecture Faculty of Art and ArchitectureTarbiat Modares UniversityTehranIran

Due to the importance of the historical context of Dezful City,investigating historic buildings is *** unfortunately,a large part of it is being *** this reason,it is essential to discover the guidelines and logic behind the architectural design of these buildings to help their reconstruction or ***,there is no logical information about the components of this context and the reconstructions are usually done according to taste and based on architecture tested or personal ***,it is necessary to find a logic behind these critical components that support the whole plan or parts of it in a particular *** purpose of this research is to discover and find the logic behind the design of this building in the historical context of *** geometrical proportions can significantly help to reconstruct buildings better and more *** this purpose,30 historical houses of Dezful were randomly selected,and their input information was drawn in 2D form in ***,the length,width,and height proportions were measured,and the obtained ratios were compared with the golden proportions and dynamic *** paper studies entrance based on ratios of√2,√3,√4,√4,√1.25 andφ(the golden section).The results show that golden proportions and proportions derived from dynamic rectangles are present in the wording of all ***,the range of ratios in the plan is from 1.34 to 2,and the content of changes in the section is from 1.22 to *** results can help architects,and particularly building owners,to reconstruct based on existing logic by discovering the proportions of the entrances of the *** is possible to administer a part of the damaged tissue and estimate its dimensions and sizes because the proportions’completeness can help revive half-destroyed historical buildings.

关键词： Proportions Historical houses House entrance Dezful city Qajar period to early Pahlavi

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Challenges in differential diagnosis between obstructive and non-obstructive azoospermia

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UroPrecision 2024年第1期2卷 30-35页

作者： safar Gamidov Taras Shatylko Alikhan Tambiev Natig Gasanov Alina Popova Abdalrahman Alrawashdeh Gennadiy Sukhikh V.I.Kulakov National Medical Research Center of Obstetrics Gynecology and PerinatologyMoscowRussia Sechenov University MoscowRussia

Background:Some cases of non-obstructive azoospermia(NOA)are characterized by normal clinical parameters,including testicular volume and levels of reproductive hormones,mimicking obstructive azoospermia(OA).Methods:We performed a retrospective review of a consecutive series of 1417 patients undergoing primary surgical sperm retrieval between 2014 and ***-stimulating hormone(FSH)level below 7.6 IU/l and normal testicular size with a long axis measurement>4.6 cm were used as criteria to suspect ***:Four hundred and eighteen patients with normal testicular volume and FSH levels had an initial diagnosis of *** them,243(58.1%)had histological signs of spermatogenic dysfunction,and 175(41.9%)had true *** hundred eleven patients had long-standing obstruction(median:16.5 years)with a median Bergmann-Kliesch score(BKS)of 5(interquartile range[IQR]:4-6)and 100%sperm retrieval rate(SRR),though some required microdissection testicular sperm extraction(microTESE).Fifty-eight patients with a history of epididymo-orchitis had a median BKS of 4(IQR:2-6)and 100%*** patients with a history of unjustified medical treatment for male infertility had a median BKS of 3(IQR:1-4)and 80%***-four patients had uniform maturation arrest with a 5.5%SRR on ***:Men with normal testicular volume and FSH level may have evidence of spermatogenic failure on *** with complicated seminal tract obstruction commonly have hypospermatogenesis,but true NOA caused by uniform maturation arrest may also be *** counseling for suspected OA should not be overly optimistic,and couples should be warned about possibility of conversion to microTESE and risks of negative sperm retrieval.

关键词： azoospermia male infertility sperm retrieval

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Nanomaterial-assisted wearable glucose biosensors for noninvasive real-time monitoring:Pioneering point-of-care and beyond

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Nano Materials Science 2024年第3期6卷 263-283页

作者： Moein safarkhani Abdullah Aldhaher Golnaz Heidari Ehsan Nazarzadeh Zare Majid Ebrahimi Warkiani Omid Akhavan YunSuk Huh Navid Rabiee NanoBio High-Tech Materials Research Center Department of Biological Sciences and BioengineeringInha UniversityIncheon22212Republic of Korea Department of Chemistry Sharif University of TechnologyTehranIran School of Natural Sciences Massey UniversityPrivate Bag 11222Palmerston North4410New Zealand School of Chemistry Damghan UniversityDamghan36716-45667Iran School of Biomedical Engineering University of Technology SydneySydneyNSW2007Australia Department of Physics Sharif University of TechnologyP.O.Box 11155-9161TehranIran Centre for Molecular Medicine and Innovative Therapeutics Murdoch UniversityPerthWA 6150Australia School of Engineering Macquarie UniversitySydneyNew South Wales2109Australia

This review explores glucose monitoring and management strategies,emphasizing the need for reliable and userfriendly wearable sensors that are the next generation of sensors for continuous glucose *** addition,examines key strategies for designing glucose sensors that are multi-functional,reliable,and cost-effective in a variety of *** unique features of effective diabetes management technology are highlighted,with a focus on using nano/biosensor devices that can quickly and accurately detect glucose levels in the blood,improving patient treatment and control of potential diabetes-related *** potential of next-generation wearable and touch-sensitive nano biomedical sensor engineering designs for providing full control in assessing implantable,continuous glucose monitoring is also *** challenges of standardizing drug or insulin delivery doses,low-cost,real-time detection of increased blood sugar levels in diabetics,and early digital health awareness controls for the adverse effects of injectable medication are identified as unmet ***,the market for biosensors is expected to expand significantly due to the rising need for portable diagnostic equipment and an ever-increasing diabetic *** paper concludes by emphasizing the need for further research and development of glucose biosensors to meet the stringent requirements for sensitivity and specificity imposed by clinical diagnostics while being cost-effective,stable,and durable.

关键词： Glucose sensor Biosensor Wearable devices Noninvasive Real-time monitoring

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Prediction of the Behavior of a Power System Using Root Cause Failure Analysis

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Fluid Dynamics & Materials Processing 2022年第3期18卷 815-833页

作者： Seyed Mohammad Seyed Hosseini Kamran Shahanaghi safar Shasfand Iran University of Science and Technology Tehran***Iran

The thermo-economic performance of a gas turbine is simulated using a fish bone technique to characterize the major equipment failure *** a fault tree analysis and a Pareto technique are implemented to identify the related failure modes,and the percentage and frequency of failures,respectively.A pump 101 and drier 301 belonging to the Tabriz Petrochemical Company are considered for such analysis,which is complemented with a regression method to determine a behavioral model of this equipment over a twenty-year *** findings indicate that 81%of major failure factors in production equipment are related to the executive procedures(24%),human error(22%),poor quality of materials and parts(20%),and lack of personnel training(15%).

关键词： Combined heat and power root analysis thermoeconomic performance fault tree Pareto behavioral model

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Computational solution of an acid-mediated tumor-growth radial model under logistic growth regimes for normal and cancer cells

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International Journal of Biomathematics 2023年第3期16卷 45-62页

作者： Farhan Khan Mudassar Abbas Jorge E.Macias-Diaz Muhammad Bilal Khan safar M.Alghamdi Department of Mathematics and Computer Sciences University of Palermo 90133 PalermoItaly Department of Mathematics and Applications “R.Caccioppoli”University of Naples Federico iiVia Cintia 80126NaplesItaly Department of Mathematics School of Digital Technologies Tallinn University10120 TallinnEstonia Departamento de Matematicas y Fisica Universidad Autonoma de Aguascalientes AguascalientesAgs.20131Merico Department of Mathematics COMSATS University Islamabad Islambad44000 Pakistan Department of Mathematics and Statistics College of Science Taif University Taif 21944Saudi Arabia

Tumor invasion follows a complex mechanism which involves cell migration and *** study the processes in which primary and secondary metastases invade and damage the normal cells,mathematical models are often extremely *** this paper,we present a mathematical model of acid-mediated tumor growth consisting of radially symmetric reaction-diffusion *** assumption on the radial symmetry of the solutions is imposed here in view that tumors present spherical symmetry at the microscopic ***,we consider various empirical mechanisms which describe the propagation of tumors by considering cancer cells,normal cells,and the concentration of H+*** other assumptions,we suppose that these components follow logistictype growth ***,this is an important difference with respect to various other mathematical models for tumor growth available in the ***,we also add competition terms of normal and tumor cells *** carry out a balancing study of the equations of the model,and a numerical model is proposed to produce *** practical remarks derived from our assumptions are provided in the discussion of our simulations.

关键词： Cancer growth model radially symmetric system acid-mediated tumor growth computer simulations

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Relationship between fatigue life of asphalt concrete and polypropylene/polyester fibers using artificial neural network and genetic algorithm

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Journal of Central South University 2015年第5期22卷 1937-1946页

作者： Morteza Vadood Majid safar Johari Ali Reza Rahai Textile Engineering Department Amirkabir University of Technology Civil and Environmental Engineering Department Amirkabir University of Technology

While various kinds of fibers are used to improve the hot mix asphalt(HMA) performance, a few works have been undertaken on the hybrid fiber-reinforced HMA. Therefore, the fatigue life of modified HMA samples using polypropylene and polyester fibers was evaluated and two models namely regression and artificial neural network(ANN) were used to predict the fatigue life based on the fibers parameters. As ANN contains many parameters such as the number of hidden layers which directly influence the prediction accuracy, genetic algorithm(GA) was used to solve optimization problem for ANN. Moreover, the trial and error method was used to optimize the GA parameters such as the population size. The comparison of the results obtained from regression and optimized ANN with GA shows that the two-hidden-layer ANN with two and five neurons in the first and second hidden layers, respectively, can predict the fatigue life of fiber-reinforced HMA with high accuracy(correlation coefficient of 0.96).

关键词： hot mix asphalt fatigue property reinforced fiber artificial neural network genetic algorithm

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Hydroxysafflor yellow A protects against thioacetamide-induced liver fibrosis in rats via suppressing proinflammatory/fibrogenic mediators and promoting hepatic stellate cell senescence and apoptosis

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Asian Pacific Journal of Tropical Biomedicine 2023年第8期13卷 348-358页

作者： Sayed H.Seif el-Din Olfat A.Hammam Shahira M.Ezzat Samira Saleh Marwa M.safar Walaa H.El-Maadawy Naglaa M.El-Lakkany Pharmacology Department Theodor Bilharz Research InstituteWarak El-HadarImbaba P.O.Box 30Giza 12411Egypt Pathology Department Theodor Bilharz Research InstituteWarak El-HadarImbaba P.O.Box 30Giza 12411Egypt Pharmacognosy Department Faculty of PharmacyCairo UniversityCairo 11562Egypt Pharmacognosy Department Faculty of PharmacyOctober University for Modern Sciences and ArtsGizaEgypt Pharmacology and Toxicology Department Faculty of PharmacyCairo UniversityCairo 11562Egypt Pharmacology and Biochemistry Department Faculty of PharmacyThe British University in EgyptCairoEgypt

Objective:To evaluate the effect of hydroxysafflor yellow A(HSYA)on thioacetamide-induced liver ***:Thioacetamide was administered to rats intraperitoneally in doses of 200 mg/kg twice a week for 12 ***-intoxicated rats were given silymarin(50 mg/kg)or HSYA(5 mg/kg)orally every day for 8 *** enzymes,fibrosis markers,histological changes as well as immunohistochemistry of TNF-α,IL-6,p21,α-SMA,and caspase-3 were *** effect of HSYA on HSC-T6 activation/proliferation and apoptosis was also determined in ***:HSYA decreased liver enzymes,TNF-α,IL-6,and p21 expressions,hepatic PDGF-B,TIMP-1,TGF-β1,and hydroxyproline levels,as well as fibrosis score(S2 vs.S4)compared to the thioacetamide *** also downregulatedα-SMA while increasing caspase-3 ***,at 500μg/mL,HSYA had only a slightly suppressive effect on HSC proliferation,with a 9.5%***,it significantly reduced TGF-β1,inhibitedα-SMA expression,induced caspase-3 expression,and promoted cell ***:HSYA may be a potential therapeutic agent for delaying and reversing the progression of liver *** research on HSYA at higher doses and for a longer period is warranted.

关键词： Hydroxysafflor yellow A Thioacetamide Hepatic stellate cells Inflammatory markers Liver fibrosis p21 α-SMA Apoptosis

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Structural basis of SARS-CoV-2 3CL^pro and anti-COVID-19 drug discovery from medicinal plants

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Journal of Pharmaceutical Analysis 2020年第4期10卷 313-319页

作者： Muhammad Tahir ul Qamar safar MAlqahtani Mubarak AAlamri Ling-Ling Chen College of Life Science and Technology Guangxi UniversityNanning530004PR China Hubei Key Laboratory of Agricultural Bioinformatics College of InformaticsHuazhong Agricultural UniversityWuhan430070PR China Department of Pharmaceutical Chemistry College of PharmacyPrince Sattam Bin Abdulaziz University11323AlkarjSaudi Arabia

The recent pandemic of coronavirus disease 2019(COVID-19)caused by SARS-CoV-2 has raised global health *** viral 3-chymotrypsin-like cysteine protease(3CL^pro)enzyme controls coronavirus replication and is essential for its life cycle.3CL^pro is a proven drug discovery target in the case of severe acute respiratory syndrome coronavirus(SARS-CoV)and Middle East respiratory syndrome coronavirus(MERS-CoV).Recent studies revealed that the genome sequence of SARS-CoV-2 is very similar to that of ***,herein,we analysed the 3CL^pro sequence,constructed its 3D homology model,and screened it against a medicinal plant library containing 32,297 potential anti-viral phytochemicals/traditional Chinese medicinal *** analyses revealed that the top nine hits might serve as potential anti-SARS-CoV-2 lead molecules for further optimisation and drug development process to combat COVID-19.

关键词： Coronavirus SARS-CoV-2 COVID-19 Natural products Protein homology modelling Molecular docking Molecular dynamics simulation

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The Precautions Efficacy Taken among Health Care Workers While Performing Tracheostomies on COVID-19 Patients: Systematic Review

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第6期11卷 283-291页

作者： Mohaned Al safar Hosam A. Amoodi Mohammed Al-Satti Abulaziz Alsaidi East Jeddah General Hospital Jeddah Saudi Arabia University of Jeddah Jeddah Saudi Arabia Dr. Soliman Fakeeh Hospital Jeddah Saudi Arabia King Abdulaziz Medical City Jeddah Saudi Arabia International Medical Center Jeddah Saudi Arabia

Background & objectives: Coronavirus disease 19 (COVID-19) has been declared by World Health Organization as a global pandemic disease in March 2020. Acute respiratory distress syndrome is frequent complication of COVID-19 disease. Tracheostomy is needed in cases of prolonged mechanical ventilation (7 - 10 days) in patients with acute respiratory distress syndrome. Tracheostomies are highly aerosol generating procedures, Otorhinolaryngologists and Health Care Workers (HCWs) are at high risk of virus exposure. The aim of this review is to evaluate the risk of transmission of COVID-19 during tracheostomy procedure, and to review the practical recommendation and scope of the timing to reduce risk of transmission to HCW. Methods: PubMed database was searched between April 2020 to Jan 2021 using the terms “Tracheostomy AND COVID-19 AND Health Care Workers”. All the articles that shared the same aim were screened which resulted in 243 references without duplicates. The title and abstract screening excluded further 202 studies. Eventually 9 full-text studies were included. Results: Five hundred and two COVID-19 patients underwent tracheostomies during the study period. Sixty-three percent of the procedure were done through open technique, while 37% of them were done through percutaneous technique. Seventy-eight percent of them used full Personal Protective Equipment (PPE) and 44.4% used Powered Air Purifying Respirator (PAPR). Negative Pressure Rooms (NPR) were used in 67%. Conclusion: The studies showed similar negative results on HCW infection despite much variance in using PPE. However, there should be global unified recommendations and guidelines regarding tracheostomies in COVID-19 patients to prevent future HCW infection.

关键词： Tracheostomy COVID-19 Health Care Workers

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