检索结果-南通市图书馆

Quality of life and oral potentially malignant disorders: Critical appraisal and prospects

World Journal of Clinical Oncology 2018年第4期9卷 56-59页

作者： Shailesh M Gondivkar Rahul R Bhowate Amol R Gadbail sachin C sarode Shankargouda Patil Department of Oral Medicine and Radiology Government Dental College and Hospital Department of Oral Medicine and Radiology Sharad Pawar Dental College and Hospital Department of Dentistry Indira Gandhi Government Medical College and Hospital Department of Oral Pathology and Microbiology Dr. D.Y. Patil Dental College and Hospital Department of Maxillofacial Surgery and Diagnostic Sciences Division of Oral Pathology College of Dentistry Jazan University

Quality of life(QoL) is a vital and often required health outcome measure that is relevant to patient care. A healthy oral cavity enables person to perform daily activities without any limitations. However, any disturbance may result in impaired QoL. The oral health-remains an essential element of people's health and well-being. In recent years, the tradition of clinical practice and research has been changed by incorporating QoL assessment, as it helps in assessment of patients' needs and monitoring treatment responses. Oral potentially malignant disorders(OPMDs) are a group of chronic disorders including oral leukoplakia(OL), oral lichen planus and oral submucous fibrosis(OSF). It is evident that patients with OPMDs experience significant health-related symptoms, functional limitations and psycho-social impairment, compromising their Qo L. Moreover, the worsening of Qo L has been associated with advanced stages of OPMDs. Despite of increasing number of OPMD cases in recent decades, limited literature is available regarding QoL in this population. Although, there is higher prevalence of habit-related OPMDs, particularly OSF and OL in Southern Asian countries, only a few studies have been performed in these populations. Moreover, these studies administered generic Qo L instruments, which offer less sensitivity to clinical changes. However, condition-specific instruments are more sensitive and allows better measurement of QoL. As the impacts of different conditions on OHRQoL may vary, the development and validation of a QoL instrument specific to each clinical entity of OPMDs is currently needed.

关键词： Quality of life Oral potentially malignant disorders Oral submucous fibrosis Oral lichen planus Oral leukoplakia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

COVID-19 and oral cancer:Critical viewpoint

引用

World Journal of Clinical Oncology 2022年第8期13卷 725-728页

作者： Dharmarajan Gopalakrishnan sachin C sarode Gargi S sarode Namrata Sengupta Department of Periodontology Dr.D.Y.Patil Dental College and HospitalDr.D.Y.Patil VidyapeethPune 411018MaharashtraIndia Department of Oral Pathology and Microbiology Dr.D.Y.Patil Dental College and HospitalDr.D.Y.Patil VidyapeethPune 411018MaharashtraIndia

The outbreak of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has marked the beginning of a new pandemic named coronavirus disease 2019(COVID-19). The World Health Organization has announced it as a health emergency that is of international concern. The disease has been reported to cause respiratory illness, pneumonia and even hinder the immunity of an individual. Individuals with disturbed immune responses have been found to be quite susceptible to this viral infection. Oral cancer patients are also at high risk in this pandemic situation and might encounter severe detrimental outcomes. Angiotensin receptors, documented in studies as the path of entry of this virus, are highly expressed in the epithelial cells of oral mucosa, making the group of individuals with oral cancers even more vulnerable. Extracellular matrix metalloproteinase inducer is another potential target for SARS-CoV-2. An exhaustion of angiotensin converting enzyme 2 cell receptors leads to protumoral effects, whereas a downregulation of extracellular matrix metalloproteinase inducer leads to antitumoral effects. Thus, it causes a variation of the biological behavior of the tumor. This article focusses on the molecular mechanisms, effects and pathophysiology of COVID-19 in oral squamous cell carcinoma patients. The different molecular changes in oral squamous cell carcinoma in the background of COVID-19 will modify various environmental factors for this pathology and have an effect on the carcinogenesis process. Understanding the behavior of the tumor will help plan advanced treatment strategies for oral squamous cell carcinoma patients in the background of COVID-19.

关键词： COVID-19 SARS-CoV-2 Oral cancer Head and neck carcinomas Oral squamous cell carcinoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proteomic profiling of various human dental stem cells-a systematic review

引用

World Journal of Stem Cells 2020年第10期12卷 1214-1236页

作者： Jagadish Hosmani Khalil Assiri Hussain Mohammed Almubarak Master Luqman Mannakandath Ahmed Al-Hakami Shankargouda Patil Deepa Babji sachin sarode Anantharam Devaraj Harish C Chandramoorthy Diagnostic Dental Sciences College of DentistryKing Khalid UniversityAbha 61471AsirSaudi Arabia Diagnostic Dental Sciences King Khalid UniversityAbha 61471AsirSaudi Arabia Center for Stem Cell Research and Department of Microbiology and Clinical Parasitology King Khalid UniversityAbha 61421AsirSaudi Arabia Maxillofacial Surgery and Diagnostic Sciences Division of oral PathologyJazan 45142JazanSaudi Arabia Department of Oral Pathology and Microbiology Maratha Mandal's NG Halgekar Institute of Dental Sciences and Research CentreBelgaun 590010KarnatakaIndia Department of Oral Pathology Y Patil Dental College and HospitalPune 411018MaharashtraIndia

BACKGROUND The proteomic signature or profile best describes the functional component of a cell during its routine metabolic and survival *** complexity in differentiation and maturation is observed in stem/progenitor *** role of functional proteins at the cellular level has long been attributed to anatomical niches,and stem cells do not deflect from this *** dental stem cells(hDSCs),on the whole,are a combination of mesenchymal and epithelial coordinates observed throughout craniofacial bones to *** To specify the proteomic profile and compare each type of hDSC with other mesenchymal stem cells(MSCs)of various ***,we analyzed the characteristics of the microenvironment and preconditioning changes associated with the proteomic profile of hDSCs and their influence on committed lineage *** Literature searches were performed in PubMed,EMBASE,Scopus,and Web of Science databases,from January 1990 to December *** extra inquiry of the grey literature was completed on Google Scholar,ProQuest,and *** MeSH terms(PubMed)and keywords related to dental stem cells were used independently and in *** The initial search resulted in 134 *** the 134 full-texts assessed,96 articles were excluded and 38 articles that met the eligibility criteria were *** overall assessment of hDSCs and other MSCs suggests that differences in the proteomic profile can be due to stem cellular complexity acquired from varied tissue sources during embryonic ***,our comparison of the proteomic profile suffered inconsistencies due to the heterogeneity of various *** believe that the existence of a heterogeneous population of stem cells at a given niche determines the modalities of regeneration or tissue *** prominences to the differences present between various hDSCs have been reasoned *** Systematic review on proteomic studies of various hDS

关键词： Apical papilla stem cells Dental follicle stem cells Dental pulp stem cells Periodontal ligament stem cells Proteomics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：