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Deep learning models for tuberculosis detection and infected region visualization in chest X-ray images

Intelligent Medicine 2024年第2期4卷 104-113页

作者： Vinayak Sharma Nillmani sachin kumar gupta Kaushal kumar Shukla School of Electronics and Communication Engineering Shri Mata Vaishno Devi University Jammu and KashmirIndia School of Biomedical Engineering Indian Institute of TechnologyBanaras Hindu UniversityVaranasiIndia Department of Computer Science and Engineering Indian Institute of TechnologyBanaras Hindu UniversityVaranasiIndia

Objective Tuberculosis(TB)is among the most frequent causes of infectious-disease-related *** being treatable by antibiotics,tuberculosis often goes misdiagnosed and untreated,especially in rural and low-resource *** X-rays are frequently used to aid diagnosis;however,this presents additional challenges because of the possibility of abnormal radiological appearance and a lack of radiologists in areas where the infection is most *** deep-learning-based imaging techniques for computer-aided diagnosis has the potential to enable accurate diagnoses and lessen the burden on medical *** the present work,we aimed to develop deep-learning-based segmentation and classification models for accurate and precise detection of tuberculosis in chest X-ray images,with visualization of infection using gradient-weighted class activation mapping(Grad-CAM)*** First,we trained the UNet segmentation model using 704 chest X-ray radiographs taken from the Montgomery County and Shenzhen Hospital ***,we implemented the trained UNet model on 1,400 tuberculosis and control chest X-ray scans to segment the lung *** images were taken from the National Institute of Allergy and Infectious Diseases(NIAID)TB portal program ***,we applied the deep learning Xception model to classify the segmented lung region into tuberculosis and normal *** further investigated the visualization capabilities of the model using Grad-CAM to view tuberculosis abnormalities in chest X-rays and discuss them from radiological *** For segmentation by the UNet model,we achieved accuracy,Jaccard index,Dice coefficient,and area under the curve(AUC)values of 96.35%,90.38%,94.88%,and 0.99,*** classification by the Xception model,we achieved classification accuracy,precision,recall,F1-score,and AUC values of 99.29%,99.30%,99.29%,99.29%,and 0.999,*** Grad-CAM heatmap images from the tuberculos

关键词： Tuberculosis Artificial intelligence Deep learning Segmentation Classification Chest X-ray

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Secure and resilient improved image steganography using hybrid fuzzy neural network with fuzzy logic

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Journal of Safety Science and Resilience 2024年第1期5卷 91-101页

作者： sachin Dhawan Hemanta kumar Bhuyan Subhendu kumar Pani Vinayakumar Ravi Rashmi gupta Arun Rana Alanoud Al Mazroa Dorset College King George BlvdSurreyBritish ColumbiaCanada Department of Information Technology Vignan’s Foundation for ScienceTechnology and Research(Deemed to be University)Andhra PradeshIndia Krupajal Computer Academy Biju Patnaik University of Technology(BPUT)Rourkela 751002India Center for Artificial Intelligence Prince Mohammad Bin Fahd UniversityKhobarSaudi Arabia NSUT East Campus(Formerly AIACTRDelhi 110031India(Affiliated to Guru Gobind Singh Inderaprastha University))Dwarka 110078India Department of Computer Science and Engineering Galgotias College of Engineering and Technology Greater Noida 201310Uttar PradeshIndia Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman University(PNU)P.O.Box 84428Riyadh 11671Saudi Arabia

The exponential growth in communication networks,data technology,advanced libraries,and mainly World Wide Web services has played a pivotal role in facilitating the retrieval of various types of information as ***,this progress has also led to security concerns related to the transmission of confidential ***,safeguarding these data during communication through insecure channels is crucial for obvious *** emergence of steganography offers a robust approach to concealing confidential information,such as images,audio tracks,text files,and video files,in suitable media carriers.A novel technique is envisioned based on back-propagation *** to the proposed method,a hybrid fuzzy neural network(HFNN)is applied to the output obtained from the least significant bit substitution of secret data using pixel value dif-ferences and exploiting the modification *** simulation and test results,it has been observed that the proposed methodology achieves secure steganography and superior visual *** the experiments,we observed that for the secret image of the cameraman,the PSNR&MSE values of the proposed technique are 61.963895 and 0.041361,respectively.

关键词： Image enhancement Image processing Steganography Deep learning Fuzzy neural combination

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Non-static plane symmetric perfect fluid solutions and Killing symmetries in f(R,T)gravity

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Communications in Theoretical Physics 2024年第2期76卷 145-150页

作者： Preeti Dalal Karanjeet Singh sachin kumar Department of Mathematics and Statistics Central University of PunjabBathinda151401PunjabIndia Department of Mathematics Jaypee University of Information TechnologySolan173234Himachal PradeshIndia

In this paper,the non-static solutions for perfect fluid distribution with plane symmetry in f(R,T)gravitational theory are ***,using the Lie symmetries,symmetry reductions are performed for considered vector fields to reduce the number of independent ***,corresponding to each reduction,exact solutions are *** vectors lead to different conserved ***,we figure out the Killing vector fields corresponding to all derived *** derived solutions are further studied and it is observed that all of the obtained spacetimes,at least admit to the minimal symmetry group which consists of δ_(y),δ_(z) and -zδ_(y)+yδ_(z).The obtained metrics,admit to 3,4,6,and 10,Killing vector *** of linear momentum in the direction of y and z,and angular momentum along the x axis is provided by all derived solutions.

关键词： Einstein field equations perfect fluid solutions f(R T)gravity killing symmetries

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A Novel Multi-objective Protection Coordination Scheme for a Microgrid with Optimal Deployment of Dual-setting ROCOV Based Relays

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Protection and Control of Modern Power Systems 2024年第4期9卷 23-38页

作者： Praveen kumar gupta Priyanshul Niranjan Niraj kumar Choudhary Nitin Singh Ravindra kumar Singh the Department of Electrical Engineering Motilal Nehru National Institute of Technology AllahabadPrayagraj 211004India

Relay coordination is crucial in electrical power systems to protect against malfunctions and damage caused by unexpected events like short *** address the challenge associated with the reverse direction of fault current,dual-setting(DS)directional over-current relays have evolved but failed to provide proper coordination during changes of load,generation,and *** the meantime,with the increasing number of DS relays,the total relay operating time tends to ***,this paper proposes a protection scheme based on the optimal deployment of conventional and dual-setting rate of change of voltage(DS-ROCOV)relays in distribution *** holds true for varying network topologies and is unaffected by variations in load and *** objective of the proposed scheme is to ensure reliable and efficient protection against faults in distribution systems by minimizing the overall operating time with the optimal number of DS-ROCOV *** proposed protection scheme’s performance is evaluated for different coordination time interval values as well as in different microgrid *** paper outlines the design and implementation of the proposed protection scheme which is validated on the modified IEEE 14-bus system using simulations in Matlab/Simulink.

关键词： Coordination time interval DS-ROCOV relay multi-objective optimization optimal-deployment protection coordination

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Autologous peripheral blood-derived orthobiologics:Different types and their effectiveness in managing knee osteoarthritis

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World Journal of Orthopedics 2024年第5期15卷 400-403页

作者： Ashim gupta Vijay kumar Jain Department of Orthopaedics and Regenerative Medicine Future BiologicsLawrencevilleGA 30043United States Department of Orthopaedics South Texas Orthopaedic Research Institute(STORI Inc.)LaredoTX 78045United States Department of Regenerative Medicine BioIntegrateLawrencevilleGA 30043United States Department of Orthopaedics and Regenerative Medicine Regenerative OrthopaedicsNoida 201301India Department of Orthopaedics Atal Bihari Vajpayee Institute of Medical SciencesDr.Ram Manohar Lohia HospitalDelhi 110001New DelhiIndia

Knees are the most commonly impacted weight-bearing joints in osteoarthritis(OA),affecting millions of people *** increasing life spans and obesity rates,the incidence of knee OA will further increase,leading to a significant increase in the economic *** treatment modalities utilized to manage knee OA have *** the last decade,the role of various autologous peripheral blood-derived orthobiologics(APBOs)for the treatment of knee OA has been extensively *** editorial provided an overview and focused on defining and shedding light on the current state of evidence based on the most recent published clinical studies concerning the use of APBO for the management of knee *** numerous studies have demonstrated promising results for these preparations,a notable gap exists in the comparative analysis of these diverse *** absence of head-to-head studies poses a considerable challenge for physicians/surgeons in determining the optimal preparation for managing knee OA and achieving sustained longterm ***,more adequately powered,multicenter,prospective,doubleblind,randomized controlled trials with longer follow-ups are needed to establish the long-term efficacy and to aid physicians/surgeons in determining the optimal APBO for the management of knee OA.

关键词： Knee osteoarthritis Platelet-rich plasma Platelet lysate Autologous conditioned serum Gold-induced cytokine Plasma rich in growth factors Growth factor concentrate Autologous protein solution Platelet-rich fibrin Hyperacute serum

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Effect of weight-adjusted antimicrobial antibiotic prophylaxis on postoperative dosage and surgical site infection incidence in total joint arthroplasty

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World Journal of Orthopedics 2024年第4期15卷 318-320页

Surgical site infections(SSI)following total joint arthroplasty pose a significant concern for both providers and patients across the ***,administration of antimicrobial antibiotic prophylaxis is used throughout the world to reduce the incidence of ***,the correct dosage and frequency of administration remains *** this editorial,we emphasized the determination of the effect of administration of weight-adjusted antimicrobial antibiotic prophylaxis regime on the incidence of SSI and postoperative dosage reduction compared to the conventionally used regime during total joint *** results demonstrated similar efficacy between both regimes with respect to the incidence of *** addition,weight-adjustment led to reduced postoperative dosage and has the potential to reduce chances of achieving lower therapeutic concentration,drug resistance,drug toxicity,and costs.

关键词： Antibiotics Antimicrobial prophylaxis Weight-adjusted Surgical site infections Total joint arthroplasty Knee arthroplasty Hip arthroplasty

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Diabetes is affecting everyone everywhere

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World Journal of Diabetes 2024年第2期15卷 305-307页

作者： Parul Chawla gupta Mona Duggal Arvind kumar Morya Department of Ophthalmology Post Graduate Institute of Medical Education&ResearchChandigarh 160012PunjabIndia School of Public Health Post Graduate Institute of Medical Education and ResearchChandigarh 160002PunjabIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia

The article titled“Accessibility and Utilization of Healthcare Services Among Diabetic Patients:Is Diabetes a Poor Man’s Ailment?”gave insights into a pandemic systemic disease known as diabetes *** modern-era pandemic affects everyone,regardless of their financial *** a result,diabetes is not a systemic disease which just involves people of low socioeconomic status.

关键词： Diabetes Incidence and prevalence Diabetes mellitus

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Smart tailoring of molecular catalysts:Mounting approach to oxygen reduction reaction

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Journal of Materials Science & Technology 2024年第1期168卷 169-184页

作者： Anuj kumar Mohd Ubaidullah Guoxin Zhang Jasvinder Kaur Saira Ajmal Mudassir Hasan Krishna kumar Yadav Hafiz M.Adeel Sharif Ram K.gupta Ghulam Yasin Nano-Technology Research Laboratory Department of ChemistryGLA UniversityMathuraUttar Pradesh 281406India Department of Chemistry College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Department of Electrical Engineering and Automation Shandong University of Science and TechnologyQingdaoShandong 266590China Institute for Advanced Study Shenzhen UniversityShenzhenGuangdong 518060China Department of Chemistry Kansas Polymer Research CenterPittsburg State UniversityPittsburgKS 66762United States Faculty of Science and Technology Madhyanchal Professional UniversityRatibadBhopal 462044India Environmental and Atmospheric Sciences Research Group Scientific Research CenterAl-Ayen UniversityThi-QarNasiriyah 64001Iraq Department of Chemical Engineering King Khalid University Saudi Arabia Department of Chemistry School of SciencesIFTM UniversityMoradabadUttar Pradesh 244102India Research Center for Eco-Environmental Engineering Dongguan University of TechnologyDongguan 523808China School of Environment and Civil Engineering Dongguan University of TechnologyDongguanGuangdong 523808China

Efficient electrocatalytic rupture of energy-rich molecules(H_(2)and O_(2))is a green approach for gener-ating clean energy for modern *** this context,porphyry-type molecular electrocatalysts act intelligently toward oxygen reduction reaction(ORR),a fundamental process in fuel cells,due to their redox-rich chemistry,which involves core metal ions and macrocyclic *** concerned scientific community has tried many times to correlate the ORR intermediates with their formation kinetics and simplify the associated multi H+/e-stages during the ORR process,constructing several volcano plots be-tween catalytic Tafel data,turnover frequencies,and overpotentials for many *** the fact that many review articles on molecular electrocatalysts for ORR have been published,understanding the strategic implications and molecular catalyst intelligence towards homogenous ORR has been poorly *** review examined the relationships between volcano plots of current *** parameters and the Sabatier principle in order to explain the intelligence of molecular electrocatalysts and approaches for their creation,as well as the difficulties and potential prospects of molecular *** facts distinguish this review from previously published articles and will pique the scien-tific community’s interest in avoiding trial-and-error procedures for catalyst creation while also allowing for more exact evaluations of the molecular catalyst’s performance.

关键词： Electrocatalysis Molecular catalysts Oxygen reduction reaction Sabatier principle

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Recent updates on nano-phyto-formulations based therapeutic intervention for cancer treatment

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Oncology Research 2024年第1期32卷 19-47页

作者： ABHISHEK WAHI MAMTA BISHNOI NEHA RAINA MEGHNA AMRITA SINGH PIYUSH VERMA PIYUSH kumar gupta GINPREET KAUR HARDEEP SINGH TULI MADHU gupta Department of Pharmaceutics School of Pharmaceutical SciencesDelhi Pharmaceutical Sciences and Research University(DPSRU)Pushp ViharNew Delhi110017India Department of Pharmaceutical Sciences Gurugram UniversityHaryana122003India Department of Life Sciences Sharda School of Basic Sciences and ResearchSharda UniversityGreater NoidaUttar Pradesh201310India Department of Biotechnology Graphic Era(Deemed to be University)DehradunUttarakhand248002India Department of Pharmacology Shobhaben Pratapbhai Patel School of Pharmacy&Technology ManagementSVKM’s NMIMSVile Parle(West)Mumbai400056India Department of Bio-Sciences and Technology Maharishi Markandeshwar Engineering CollegeMaharishi Markandeshwar(Deemed to be University)MullanaAmbala133207India

Cancer is a leading cause of death globally,with limited treatment options and several *** agents often result in toxicity which long-term conventional *** are natural constituents that are more effective in treating various diseases with less toxicity than the chemotherapeutic agents providing alternative therapeutic approaches to minimize the *** phytoconstituents act in several ways and deliver optimum effectiveness against ***,the effectiveness of phyto-formulations in the management of cancers may be constrained due to challenges related to inadequate solubility,bioavailability,and *** presents a promising avenue for transforming current cancer treatment methods through the incorporation of phytochemicals into nanosystems,which possess a range of advantageous characteristics such as biocompatibility,targeted and sustained release capabilities,and enhanced protective *** holds significant potential for future advancements in cancer ***,this review aims to provide intensive literature on diverse nanocarriers,highlighting their applications as cargos for phytocompounds in ***,it offers an overview of the current advancements in the respective field,emphasizing the characteristics that contribute to favourable outcomes in both in vitro and in vivo ***,clinical development and regulatory concerns are also discussed to check on the transformation of the concept as a promising strategy for combination therapy of phytochemicals and chemotherapeutics that could lead to cancer management in the future.

关键词： Phyto-formulations Cancer Nanocarriers Nanotechnology Clinical development

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Methyl-salicylate:A surveillance system fortriggering immunity in neighboring plants

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Journal of Integrative Plant Biology 2024年第2期66卷 163-165页

作者： Saumya Jaiswal Durgesh kumar Tripathi Ravi gupta JingHe Zhong-Hua Chen Vijay Pratap Singh Plant Physiology Laboratory Department of Botany C.M.P.Degree CollegeA Constituent Post Graduate College ofUniversity of AllahabadPrayagraj 211002India Crop Nanobiology and Molecular Stress Physiology LabAmity Institute of Organic Agriculture Amity University UttarPradeshNoida 201313India College of General Education Kookmin UniversitySeoul 02707South Korea School of Science Western Sydney UniversitySydney 2751New South WalesAustralia Hawkesbury Institute for the Environment Western SydneyUniversitySydney 2751New South WalesAustralia

Plant behavioral actions have been one of the major topicsof research in plant biology and *** actionsfrom plants are determined by their instant structural andphysical reactions to the circumstances(Bouwmeester et al.,2019).Upon sensing abiotic factors such as salinity,flooding,high temperature,drought,plants make suitable changes intheir physiology and behavior to survive such harsh conditions.

关键词： immunity neighboring salinity

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