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Effects of a sex ratio gradient on female mate-copying and choosiness in Drosophila melanogaster

Current Zoology 2018年第2期64卷 251-258页

作者： magdalena mONIER sabine NOBEL Guillaume ISABEL Etienne DANCHIN UmR-5174 Laboratoire Evolution & Diversite Biologique (EDB) Centre National de la Recherche Scientifique (CNRS) Institut de Recherche pour le Developpement (IRD) Universite de Toulouse 118 route de NarbonneF-31062 Toulouse Cedex 9 France Centre de Recherches sur la Cognition Animale (CRCA) Centre de Biologie Integrative (CBI) Centre National de la Recherche Scientifique (CNRS) Universite de Toulouse 118 route de Narbonne F-31082 Toulouse Cedex 9 France

In many sexually reproducing species, individuals can gather information about potential mates by observing their mating success. This behavioral pattern, that we call mate-copying, was reported in the fruit fly Drosophila rnelanogaster where females choosing between 2 males of contrasting phenotypes can build a preference for males of the phenotype they previously saw being chosen by a demonstrator female. As sex ratio is known to affect mate choice, our goal was to test whether mate-copying is also affected by encountered sex ratios. Thus, we created a gradient of sex ratio during demonstrations of mate-copying experiments by changing the number of females observ- ing from a central arena 6 simultaneous demonstrations unfolding in 6 peripheral compartments of a hexagonal device. We also tested whether the sex ratio experienced by females during demon- strations affected their choosiness （male courtship duration and double courtship rate） in subse- quent mate-choice tests. Experimental male：female sex ratio during demonstrations did not affect mate-copying indices, but positively affected the proportion of both males courting the female during mate-choice tests, as well as male courtship duration, the latter potentially explaining the for- mer relationship. As expected, the sex ratio affected female choosiness positively, and Drosophila females seem to have evolved a mate-copying ability independently of sex ratio, and a capacity to adapt their choosiness to male availability. This suggests that, as in many animal species, individuals, especially females, can adapt their mate choice depending on the current sex ratio.

关键词： competition Drosophila melanogaster experimental protocol mate-copying social learning sex ratio.

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Conserved Functions of Arabidopsis and Rice CC-Type Glutaredoxins in Flower Development and Pathogen Response

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molecular Plant 2009年第2期2卷 323-335页

作者： ZhenWang Shuping Xing Rainer R Birkenbihl sabine Zachgo max Planck Institute for Plant Breeding Research Plant Molecular Genetics 50829 Cologne Germany School of Biological Sciences/Plant Science initiative University of Nebraska-Lincoln Nebraska 68588 USA Botany Department University of Osnabruck 40969 Osnabruck Germany max planck Institute for Plant Breeding Research Plant Microbe Interactions 50829 Cologne Germany

Glutaredoxins （GRXs） are ubiquitous oxidoreductases that play a crucial role in response to oxidative stress by reducing disulfides in various organisms. In planta, three different GRX classes have been identified according to their active site motifs. CPYC and CGFS classes are found in all organisms, whereas the CC-type class is specific for higher land plants. Recently, two Arabidopsis CC-type GRXs, ROXY1 and ROXY2, were shown to exert crucial functions in petal and anther initiation and differentiation. To analyze the function of CC-type GRXs in the distantly related monocots, we isolated and characterized OsROXY1 and OsROXY2-two rice homologs of ROXY1. Both genes are expressed in vegetative and reproductive stages. Although rice flower morphology is distinct from eudicots, OsROXY1/2 floral expression patterns are similar to their Arabidopsis counterparts ROXY1/2. Complementation experiments demonstrate that OsROXY1 and OsROXY2 can fully rescue the roxyl floral mutant phenotype. Overexpression of OsROXY1, OsROXY2, and ROXY1 in Arabidopsis causes similar vegetative and reproductive plant developmental defects. ROXY1 and its rice homologs thus exert a conserved function during eudicot and monocot flower development. Strikingly, overexpression of these CC-type GRXs also leads to an increased accumulation of hydrogen peroxide levels and hyper-susceptibility to infection from the necrotrophic pathogen Botrytis cinerea, revealing the importance of balanced redox processes in flower organ develop- ment and pathogen defence.

关键词： ROXY1 glutaredoxin Arabidopsis rice flower development pathogen defence Botrytis cinerea.

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Clicking ferrocene to halogenated boron-doped diamond surfaces

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Rare metals 2013年第1期32卷 100-104页

作者： mei Wang sabine Szunerits Rabah Boukherroub mu-Sen Li Key Laboratory of Liquid Structure and Heredity of materials Ministry of Education Shandong University Institute of Interdisciplinary Research (IRI USR-CNRS 3078) and Institute of Electronics Microelectronics and Nanotechnology (IEMN UMR-CNRS 8520) Cite Scientifique Avenue Poincare-BP 60069 59652 Villeneuve d'Ascq France

The halogenated boron-doped diamond （BDD） surfaces were reacted with sodium azide through a nucle- ophilic substitution reaction. The resulting azide-terminated BDD surfaces were used to trigger the ＂click＂ reaction. Because of the attractive electrochemical properties of ferrocene-containing molecules, such as fast electron transfer rates, reversible redox activities, and favorable redox potentials, we show that ferrocene derivatives can be grafted onto non-oxidized diamond surfaces by ＂click chemistry＂. These redox-active ferrocene-containing layers on a BDD surface, because of their ability to store and release charges reversibly, have the potential to be used as hybrid molecular/semiconductor memory devices.

关键词： Halogenated Azide Click chemistry Ferrocene

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Risk factors for colonic diverticular bleeding:A Westernized community based hospital study

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World Journal of Gastroenterology 2009年第4期15卷 457-461页

作者： Antje Jansen sabine Harenberg Uwe Grenda Christoph Elsing Department of Gastroenterology St.Elisabeth Hospital

AIm： To evaluate the risk factors-other than nonsteroidal anti-inflammatory drugs-for colonic diverticular bleeding in a westernized population. mETHODS： One hundred and forty patients, treated for symptomatic diverticular disease in a community based hospital, were included. Thirty （21%） had signs of diverticular bleeding. Age, gender, and the results of colonoscopy were collected and compared to a group of patients with nonbleeding symptomatic diverticulosis. Records were reviewed for comorbidities, such as obesity, alcohol consumption, smoking habits and metabolic diseases. Special emphasis was put on arterial hypertension, cardiovascular events, diabetes mellitus, hyperuricemia and hypercholesterinemia. RESULTS： There was no difference between patients with diverticular hemorrhage and those with nonbleeding symptomatic diverticulosis regarding gender ratio （male/female 9/21 vs 47/63） and diverticular Iocalisation. Bleeding patients differed in respect to age （73.4± 9.9 vs 67. 8± 13.0, P 〈 0.013）. Significant differences were found between both groups regarding the presence of hyperuricemia and use of steroids and nonsteroidal anti-inflammatory drugs. Patients with three concomitant metabolic diseases were also identified as being at risk of bleeding. A forward stepwise logistic regression analysis revealed steroids, hyperuricemia and the use of calcium-channel blockers as independent risk factors of ***： Beside nonsteroidal anti-inflammatory steroid drug use, antihypertensive medication and concomitant arteriosclerotic diseases are risk factors for colonic diverticular hemorrhage. Our results support the hypothesis of an altered arteriosclerotic vessel as the source of bleeding.

关键词： Diverticula Gastrointestinal bleeding Arteriosclerosis Risk factors Calcium channel blocker

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Stereotactic body radiation therapy in patients with hepatocellular carcinoma: A mini-review

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World Journal of Gastrointestinal Oncology 2019年第5期11卷 367-376页

作者： sabine Gerum Alexandra D Jensen Falk Roeder Department of Radiation Oncology University Hospital LMU Munich Department of Radiation Oncology University Hospital Gie?en and Marburg CCU molecular Radiation Oncology German Cancer Research Center Department of Radiotherapy and Radiation Oncology Paracelsus Medical University

Stereotactic body radiation therapy(SBRT) is an emerging treatment for hepatocellular carcinoma. This technique results in excellent local control rates with favorable toxicity profile despite being predominantly used in heavily pretreated patients or those unsuitable for other local therapies. SBRT may be used as a sole treatment or in combination with other local therapies as well as a bridging strategy for patient awaiting liver transplants. This brief review describes current practice of SBRT with respect to radiation technique, patient selection and treatment concepts. It summarizes available evidence from retroand prospective studies evaluating SBRT alone, SBRT in combination with other treatments and SBRT compared to other local treatment approaches.

关键词： Hepatocellular carcinoma Stereotactic body radiation therapy Local-ablative treatment Combination approaches mini-review

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Spatial/temporal indexing and information visualization genre for environmental digital libraries

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2005年第11期 69-82页

作者： GRUNWALD sabine USA Florida 32611 Department of Soil and Water Science University of Florida Gainesville

Protecting and preserving our environmental systems require the ability to understand the spatio-temporal distri- bution of soils, parent material, topography, and land cover as well as the effects of human activities on ecosystems. Space-time modelling of ecosystems in an environmental digital library is essential for visualizing past, present, and future impacts of changes occurring within such landscapes (e.g., shift in land use practices). In this paper, we describe three novel features, spa- tio-temporal indexing, visualization, and geostatistical genre, for the environmental digital library, Environmental Visualization and Geographic Enterprise System (ENVISAGE), currently in progress at the University of Florida.

关键词： Spatio-temporal indexing Geostatistics GIS (Geographic Information System) Visualization Environmental - - --digital library Spatio-temporal search

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Heritability and Variability of Quality Parameters of Tomatoes in Outdoor Production

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Research 2020年第1期2020卷 1099-1107页

作者： Christian Zorb Hans-Peter Piepho sabine Zikeli Bernd Horneburg University of Hohenheim Institute of Crop Science70593 StuttgartGermany University of Kassel Section of Organic Plant Breeding and Agrobiodiversity27213 WitzenhausenGermany

The tomato is the most important vegetable *** England,outdoor tomatoes are widely grown by amateur gardeners,with the number of their allotment plots exceeding *** instance,in Germany,only about 16%of tomato plants are cultivated according to organic standards,although these rates are expected to *** for yield and fruit quality can increase resource ***,we need to evaluate the variability of yield and fruit quality parameters,to calculate the heritability of these traits and to identify superior genotypes for organic outdoor tomato production and *** these aims,we grew 24 tomato genotypes of diverse origins in a two-year field *** heritability of quality traits such as glucose,fructose,organic acid,and lycopene was *** medium heritability for yield suggests that trials with a larger number of locations are needed for the reliable selection of this *** correlations of sugar concentrations with fruit weight and of organic acid concentration with fruit weight and yield suggest trade-offs in breeding for larger fruits and higher *** for increased lycopene content is not subject to these challenges;the concentrations of the primary metabolite sugars and organic acids are positively correlated.

关键词： breeding sugar exceeding

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Serum levels of soluble Fas, nitric oxide and cytokines in acute decompensated cirrhotic patients

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World Journal of Gastroenterology 2007年第3期13卷 421-425页

作者： Christoph Elsing sabine Harenberg Wolfgang Stremmel Thomas Herrmann Department of Gastroenterology St. Elisabeth Hospital Dorsten Germany Department of Gastroenterology University of Heidelberg Germany

AIm： To evaluate plasma levels of nitrite/nitrate （NOx）, soluble Pas （spas） antigen, tumor necrosis factor alpha （TNF-α） and interleukin-6 （IL-6） in patients with compensated and acute decompensated cirrhosis and to evaluate mediators causing acute decompensation in liver cirrhosis, mETHODS： This prospective study was conducted in the medical intensive care unit of an academic tertiary center, Fifty-five patients with acute decompensation （gastrointestinal hemorrhage, encephalopathy, hydropic decompensation） and twenty-five patients with compensated liver drrhosis were included, Blood samples were taken for analyses of spas, Nox, IL-6, TNF-α, Liver enzymes and kidney functions were also tested, RESULTS： In patients with acute decompensation, plasma spas levels were higher than in non-decompensated patients （15305 ± 4646 vs 12458± 4322 pg/mL, P 〈 0.05）. This was also true for the subgroup of patients with alcoholic liver cirrhosis （P 〈 0.05）. The other mediators were not different and none of the parameters predicted survival, except for ALT （alanine-aminotransferase）. In patients with portal-hypertension-induced acute hemorrhage, NOx levels were significantly lower than in patients with other forms of decompensation （70.8 ± 48.3 vs 112.9 ± 74.9 pg/mL, P 〈 0.05）. When NOx levels were normalized to creatinine levels, the difference disappeared. IL-6, TNF-α and spas were not different between bleeders and non-bleeders. In decompensated patients spas, IL-6 and NOx levels correlated positively with creatinine levels, while IL-6 levels were dependent on Child class. CONCLUSION： In acute decompensated cirrhotic patients sPas is increased, suggesting a role of apoptosis in this process and patients with acute bleeding have lower NOx levels, However, in this acute complex clinical situation, kidney function seems to have a predominant influence on mediator levels,

关键词： Variceal hemorrhage Liver cirrhosis Cytokine Nitrite/nitrate Soluble Fas

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HCV-RNA positivity in peripheral blood mononuclear cells of patients with chronic HCV-infection: does it really mean viral replication?

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World Journal of Gastroenterology 2001年第2期7卷 228-234页

作者： Volker meier sabine mihm Perdita Wietzke-Braun Guliano Ramadori Georg-August-Universitat gottingen Zentrum innere medizinAbteilung Für Gastroenterologie Und EndokrinologieRobert-Koch-Straβe 4037075 GottingenGermany

AIm: To analyze the association of HCV-RNA with peripheral blood mononuclear cells (PBmC) and to answer the question whether HCV-RNA positivity in PBmC is due to viral replication. mETHODS: HCV-RNA was monitored in serum and PBmC preparations from 15 patients with chronic HCV infection before, during and after an IFN-alpha therapy using a nested RT/PCR technique. In a second approach, PBmC from healthy donors were incubated in HCV positive plasma. RESULTS: In the IFN-alpha responding patients,HCV-RNA disappeared first from total RNA preparations of PBmC and then from serum. In contrast, in relapsing patients, HCV-RNA reappeared first in serum and then in PBmC. A quantitative analysis of the HCV-RNA concentration in serum was performed before and after transition from detectable to non detectable HCV-RNA in PBmC-RNA and vice versa. When HCV-RNA was detectable in PBmC preparations, the HCV concentration in serum was significantly higher than the serum HCV-RNA concentration when HCV-RNA in PBmC was not detectable. Furthermore, at no time during the observation period was HCV specific RNA observed in PBmC, if HCV-RNA in serum was under the detection limit. Incubation of PBmC from healthy donors with several dilutions of HCV positive plasma for two hours showed a concentration dependent PCR positivity for HCV-RNA in reisolated PBmC. CONCLUSION: The detectability of HCV-RNA in total RNA from PBmC seems to depend on the HCV concentration in serum. Contamination or passive adsorption by circulating virus could be the reason for detection of HCV-RNA in PBmC preparations of chronically infected patients.

关键词： Adult Aged Antiviral Agents Female Hepacivirus Hepatitis C, Chronic Humans Interferon-alpha Leukocytes, mononuclear male middle Aged RNA, Viral Research Support, Non-U.S. Gov't Reverse Transcriptase Polymerase Chain Reaction Viral Load Virus Replication

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ARRIAN AND VISUAL ARTS

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Journal of Ancient Civilizations 2014年第1期29卷 87-101页

作者： sabine müller University of Innsbruck Kiel University

*** Flavius Arrianus from Nicomedia in Bithynia is regarded as a prime example for the successful blend of Roman and Greek identity in imperial *** his writings,he proudly presents himself as a Roman offi cial and Greek intellectual.1Both parts of his polyvalent identity served him as elements of his symbolic capital.2His Roman political-military persona complemented his image as

关键词： Roman intellectual political VISUAL himself Greek

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