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Asian Pacific Journal of Tropical Medicine 2011年第11期4卷 883-888页

作者： Rajesh J Mandade sa s.eenivas.dm sakarkar Avijit Choudhury Pharmacology Department S.N.Institute of PharmacyPusadIndia Guru Nanak Institute of Pharmacy IbrahimpattnamHyderabad.(A.P.) India s.N.Institute of Pharmacy PusadIndia Pharmacology Department Shree Dhanvantary college pharmacyKimIndia

Objective:To explore the effects of extract of Hibiscus rosasinensis(***) on the volume,free and total acidity of gastric secretion induced by ***:Animals were kept on fasting for 48 *** the pylorus of each animal was *** were randomly divided into 5 groups and treated by carbachol at 600μg/*** animals in groupⅡ-Ⅴwere treated by *** extract at 250 and 500 mg/kg body weight,cimetidine at 2.5 mg/ kg and verapamil at 10 mg/kg body weight intraperitoneally,*** volume,free and total acidity of gastric secretion were observed and ***:It was found that the extract significantly reduced the volume,free and total acidity of gastric secretion(Pse reductions were comparable to cimetidine and *** the reduction in the volume and free acidity were more significant in cimetidine and verapamil treated group indicating that cimetidine and verapamil were more ***:The extract of *** can reduced the volume,free and total acidity of gastric secretion,and can be used effectively in the treatment of peptic ulcer.

关键词： Verapamil Cimetidine Carbachol Hibiscus rosasinensis Rats

Flexible and ultrathin dopamine modified MXene and cellulose nanofiber composite films with alternating multilayer structure for superior electromagnetic interference shielding performance

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Frontiers of physics 2023年第3期18卷 155-166页

作者： Qiugang Liao Hao Liu Ziqiang Chen Yinggan Zhang Rui Xiong Zhou Cui Cuilian Wen Baisheng sa Multiscale Computational Materials Facility and Key Laboratory of Eco-materials Advanced TechnologyCollege of Materials Science and EngineeringFuzhou UniversityFuzhou 350100China College of Materials Fujian Provincial Key Laboratory of Theoretical and Computational ChemistryXiamen UniversityXiamen 361005China

With the development of modern electronics,especially the next generation of wearable electromagnetic interference(EMI)shielding materials requires flexibility,ultrathin,lightweight and robustness to protect electronic devices from radiation *** this work,the flexible and ultrathin dopamine modified MXene@cellulose nanofiber(dm@CNF)composite films with alternate multilayer structure have been developed by a facile vacuum filtration induced self-assembly *** multilayered dm@CNF composite films exhibit improved mechanical properties compared with the homogeneous dm/CNF *** adjusting the layer number,the multilayered dm3@CNF2 composite film exhibits a tensile strength of 48.14 MPa and a toughness of 5.28 MJ·m^(–3) with a thickness about 19μ*** that,the dm@CNF film with annealing treatment achieves significant improvement in conductivity(up to 17264 s·m^(–1))and EMI properties(sE of 41.90 dB and ssE/t of 10169 dB·cm^(2)·g–1),which still maintains relatively high mechanical *** is highlighted that the ultrathin multilayered dm@CNF film exhibits superior EMI shielding performance compared with most of the metal-based,carbon-based and MXene-based shielding materials reported in the *** results will offer an appealing strategy to develop the ultrathin and flexible MXene-based materials with excellent EMI shielding performance for the next generation intelligent protection devices.

关键词： MXene dopamine cellulose nanofibers electromagnetic interference shielding performance mechanical properties

Evaluating new biomarkers for diabetic nephropathy:Role ofα2-macroglobulin,podocalyxin,α-L-fucosidase,retinol-binding protein-4,and cystatin C

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World Journal of Diabetes 2024年第6期15卷 1212-1225页

作者： Jing-Jing Li Ru-La sa Yu Zhang Zhao-Li Yan Department of Infectious Diseases Inner Mongolia Medical UniversityHohhot First HospitalHohhot 010000Inner Mongolia Autonomous RegionChina Department of Endocrinology The Affiliated Hospital of Inner Mongolia Medical UniversityHohhot 010000Inner Mongolia Autonomous RegionChina Department of Dermatology Inner Mongolia Autonomous Region People’s HospitalHohhot 010000Inner Mongolia Autonomous RegionChina

BACKGROUND The intricate relationship between type 2 diabetes mellitus(T2dm)and diabetic nephropathy(DN)presents a challenge in understanding the significance of various biomarkers in *** To elucidate the roles and diagnostic values ofα2-macroglobulin(α2-MG),podocalyxin(PCX),α-L-fucosidase(AFU),retinol-binding protein-4(RBP-4),and cystatin C(CysC)in *** From December 2018 to December 2020,203 T2dm patients were enrolled in the *** these,115 were diagnosed with DN(115 patients),while the remaining 88 patients were classified as *** urinary levels ofα2-MG,PCX,and AFU and the serum concentrations RBP-4 and CysC were measured in conjunction with other relevant clinical indicators to evaluate their potential correlations and diagnostic *** After adjustments for age and gender,significant positive correlations were observed between the biomarkers CysC,RBP-4,α2-MG/urinary creatinine(UCr),PCX/UCr,and AFU/UCr,and clinical indicators such as urinary albumin-to-creatinine ratio(UACR),serum creatinine,urea,24-h total urine protein,and neutrophil-to-lymphocyte ratio(NLR).Conversely,these biomarkers exhibited negative correlations with the estimated glomerular filtration rate(Pstic(ROC)curve analysis further demonstrated the diagnostic performance of these biomarkers,with UACR showcasing the highest area under the ROC curve(AUC^(ROC))at *** This study underscores the diagnostic significance ofα2-MG,PCX,and AFU in the development of *** biomarkers RBP-4,CysC,PCX,AFU,andα2-MG provide promising diagnostic insights,while UACR is the most potent diagnostic biomarker in assessing DN.

关键词： α2-macroglobulin Podocalysin α-L-fucosidase Retinol binding protein-4 Cystatin C Diabetic nephropathy

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刺激的时间模式在知觉学习中的作用

刺激的时间模式在知觉学习中的作用

现代管理策略降低儿童、青少年和年轻成人肥厚型心肌病患者心血管病死亡率

第一届全国脑与认知科学学术研讨会

作者：张俊云蒯曙光 sa Klein dm Levi 余聪中国科学院神经科学研究所中国科学院神经科学研究所 school of Optometry UC Berkeley school of Optometry UC Berkeley 中国科学院神经科学研究所

＜正＞研究背景及目的:知觉学习可以提高人对视觉刺激的属性（如对比度、空间频率和方向）的辨别能力。以往的研究更多关注刺激的空间因素在知觉学习中的影响,而对刺激时间因素的作用知之甚少。本研究试图了解刺激的时间模式（如刺激...

＜正＞研究背景及目的:知觉学习可以提高人对视觉刺激的属性（如对比度、空间频率和方向）的辨别能力。以往的研究更多关注刺激的空间因素在知觉学习中的影响,而对刺激时间因素的作用知之甚少。本研究试图了解刺激的时间模式（如刺激呈现的序列、节奏）在知觉学习中的作用,并进一步探讨知觉学习的机制。

关键词：

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中华高血压杂志 2015年第10期23卷 973-973页

作者：刘莉叶鹏 Maron BJ Rowin EJ Casey sa Lesser JR Garberich RF McGriff dm Maron Ms

青年时期一直被认为是肥厚型心肌病（hypertrophic cardiomyopathy,HCM）发生风险最高的时间,尤其是猝死风险。过去的20年间发现了许多可靠的识别高危患者的指标,并利用植入式心脏除颤器（implantable cardiac defibrillator,ICD）预防... 详细信息

青年时期一直被认为是肥厚型心肌病（hypertrophic cardiomyopathy,HCM）发生风险最高的时间,尤其是猝死风险。过去的20年间发现了许多可靠的识别高危患者的指标,并利用植入式心脏除颤器（implantable cardiac defibrillator,ICD）预防猝死,同时也产生了当前其他的治疗方案。

关键词：肥厚型心肌病高危患者现代管理心血管病年轻成人死亡率青少年儿童

Impact of Cooking Time on the Physicochemical and Nutritional Properties of Macrotermes subhyalinus and Imbrasia obscura

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Food and Nutrition sciences 2023年第4期14卷 369-384页

作者： Clément saïdou Kouabiteu Marivaux Lesage Djouffa Bouba Adji Mohammadou Ahmed Ali Clergé Tchiegang Department of Food Engineering and Quality Control University Institute of Technology University of Ngaoundere Ngaoundere Cameroon Department of Food sciences and Nutrition National School of Agro-Industrial Sciences University of Ngaoundere Ngaoundere Cameroon

Insects are considered as an important source of essential nutrients because of their nutritional value which in turn is related to proteins, lipids, and mineral elements. In order to optimise the nutritional quality of insects, there is a need to identify processing and cooking methods that will result in higher retention of quality nutrients. several researchers have investigated the effect of cooking methods on the nutritional quality of edible insects. The effect of cooking time on physico-chemical and nutritional parameters of Macrotermes subhyalinus Rambur and Imbrasia obscura Butler was evaluated in this study. M. subhyalinus échantillons were fried and grilled at a temperature of 150°C at intervals of 3, 6, 9, and 12 minutes. I. obscura was initially boiled at 93.4°C for 6, 9, 12, and 15 minutes. Then, I. obscura which had been boiled for six minutes at 93.4°C was fried for 3, 6, 9, and 12 minutes, respectively, at 150°C. The analysis used the pre-levered samples from those various times. The results obtained for M. subhyalinus and I. obscura respectively demonstrate that these two insects comprise primarily proteins (36.83 and 59.04 g/100g dm), lipids (54.24 and 18.67 g/100g dm), and total mineral content (5.87 and 7.82 g/100g dm). With increased cooking time, physical-chemical and nutritional indicators decreased significantly (p 0.05). When the insects were fried and toasted, the total mineral content increased, but only the lipids increased considerably (p 0.05). Fry for 3 to 6 minutes and toast for 3 to 6 minutes are treatments for M. subhyalinus that better conserve nutrients. To preserve the nutritional value, scalding I. obscura for 6 minutes and combining it with frying it for 3 minutes are highly advised.

关键词： Entomophagy Insects Processing Nutritional Value

Non-thermal atmospheric-pressure positive pulsating corona discharge in degradation of textile dye Reactive Blue 19 enhanced by Bi_(2)O_(3) catalyst

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Plasma science and Technology 2024年第2期26卷 104-113页

作者： Milica PETROVIC Dragan RADIVOJEVIC sasa RANCEV Nena VELINOV Milos KOsTIC Danijela BOJIC Aleksandar BOJIC Department of Chemistry Faculty of Sciences and MathematicsUniversity of NisNis 18000Serbia Department of Physics Faculty of Sciences and MathematicsUniversity of NisNis 18000Serbia

In this work,monoclinic Bi_(2)O_(3) was applied for the first time,to the best of our knowledge,as a catalyst in the process of dye degradation by a non-thermal atmospheric-pressure positive pulsating corona *** research focused on the interaction of the plasma-generated species and the catalyst,as well as the role of the catalyst in the degradation *** decomposition of the anthraquinone reactive dye Reactive Blue 19(RB 19) was performed in a selfmade reactor ***_(2)O_(3) was prepared by electrodeposition followed by thermal treatment,and characterized by x-ray diffraction,scanning electron microscopy and energy-dispersive xray *** was observed that the catalyst promoted decomposition of plasma-generated H_(2)O_(2) into ·OH radicals,the principal dye-degrading reagent,which further attacked the dye *** catalyst improved the decolorization rate by 2.5 times,the energy yield by 93.4%and total organic carbon removal by 7.1%.Excitation of the catalyst mostly occurred through strikes by plasma-generated reactive ions and radical species from the air,accelerated by the electric field,as well as by fast electrons with an energy of up to 15 eV generated by the streamers reaching the liquid *** strikes transferred the energy to the catalyst and created the electrons and holes,which further reacted with H_(2)O_(2) and water,producing ·OH *** was indentified as the primary role of the catalyst in this *** reactions followed pseudo first-order *** of H_(2)O_(2) and the dye degradation rate increased with increase in the input *** optimal catalyst dose was 500 mg·dm^(-3).The decolorization rate was a little lower in river water compared with that in deionized water due to the side reactions of ·OH radicals with organic matter and inorganic ions dissolved in the river water.

关键词： corona RB 19 Bi_(2)O_(3) catalyst degradation

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动态红外温度仪评估婴幼儿血管瘤的初步研究

中国口腔颌面外科杂志 2016年第3期14卷 212-212页

作者： Burkes sa Patel M Adams dm

增殖期婴幼儿血管瘤（IH）由于血流丰富,灌注充足,常常导致皮温升高;而消退期IH由于细胞凋亡,灌注减少,皮温恢复正常。对疗效的客观评价能够为临床医师继续治疗提供指导。

关键词：婴幼儿血管瘤温度仪皮温消退期临床医师细胞凋亡功能成像增殖期回复状态临床就诊

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糖尿病视网膜病变的发病特点及其民族差异

解放军医学杂志 2020年第6期45卷 663-671页

作者：郭萨日娜朱丹陶勇内蒙古医科大学附属医院眼科呼和浩特010050 首都医科大学附属北京朝阳医院眼科北京100020

糖尿病视网膜病变(DR)是糖尿病(dm)最常见的微血管病变之一,本质上是由胰岛素分泌不足或活性降低引起血糖代谢异常所致,其发病机制复杂,既与多基因遗传有关,又受环境因素影响。目前,国内外对DR的研究逐步加深,但缺乏对中国少数民族DR相... 详细信息

糖尿病视网膜病变(DR)是糖尿病(dm)最常见的微血管病变之一,本质上是由胰岛素分泌不足或活性降低引起血糖代谢异常所致,其发病机制复杂,既与多基因遗传有关,又受环境因素影响。目前,国内外对DR的研究逐步加深,但缺乏对中国少数民族DR相关的研究。为此,该文对中国部分少数民族DR的发病特点及其民族差异进行综述。

关键词：糖尿病视网膜病变病因学流行病学民族差异少数民族

Hyporeninemic hypoaldosteronism and diabetes mellitus:Pathophysiology assumptions,clinical aspects and implications for management

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World Journal of Diabetes 2016年第5期7卷 101-111页

作者： Andre Gustavo P sousa Joao Victor de sousa Cabral William Batah El-Feghaly Luísa silva de sousa Adriana Bezerra Nunes Department of Clinical Medicine Federal University of Rio Grande do Norte Onofre Lopes University Hospital Federal University of Rio Grande do Norte

Patients with diabetes mellitus(dm) frequently develop electrolyte disorders,including *** most important causal factor of chronic hyperkalemia in patients with diabetes is the syndrome of hyporeninemic hypoaldosteronism(HH),but other conditions may also ***,as hyperkalemia is related to the blockage of the renin-angiotensin-aldosterone system(RAAs) and HH is most common among patients with mild to moderate renal insufficiency due to diabetic nephropathy(DN),the proper evaluation and management of these patients is quite *** its obvious relationship with diabetic nephropathy,HH is also related to other microvascular complications,such as DN,particularly the autonomic *** confirm the diagnosis,plasma aldosterone concentration and the levels of renin and cortisol are measured when the RAAs is *** addition,synthetic mineralocorticoid and/or diuretics are used for the treatment of this ***,few studies on the implications of HH in the treatment of patients with dm have been conducted in recent years,and therefore little,if any,progress has been *** comprehensive review highlights the findings regarding the epidemiology,diagnosis,and management recommendations for HH in patients with dm to clarify the diagnosis of this clinical condition,which is often neglected,and to assist in the improvement of patient care.

关键词： Hyporeninemic Diabetes Hyperkalemia Renal tubular acidosis Hypoaldosteronism