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Research progress and strategies for multifunctional rapeseed： A case study of China

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Journal of Integrative Agriculture 2016年第8期15卷 1673-1684页

作者： FU Dong-hui jianG Ling-yan Annaliese S Mason XIAO Mei-li ZHU Long-rong LI Li-zhi ZHOU Qing-hong shen chang-jian HUANG Chun-hui Key Laboratory of Crop Physiology Ecology and Genetic Breeding Ministry of Education/Agronomy College Jiangxi Agricultural University Nanchang 330045 P.R.China Department of Biochemistry University of Missouri Columbia 65211 USA Department of Plant Breeding IFZ Research Centre for Biosystems Land Use and Nutrition Justus Liebig University Heinrich- Buff-Ring 26-32 Giessen 35392 Germany jiangxi Province Key Laboratory of Animal Nutrition/Engineering Research Center of Feed Development Jiangxi Agricultural University Nanchang 330045 P.R. China Linli County Rural Practical Technology Research Institute Changde 415000 P.R. China

financially supported by the Key R＆D Program of jiangxi Province of China （20152ACF60010）;the Key Projects of Hunan Science and Technology Support Program of China （Application research of Guiye A male sterile line）;the Research Project of Humanities and Social Sciences in Universities of jiangxi Province, China（JC1315）;supported by Emmy Noether DFG grant MA 6473/1-1

关键词： multifunctional rapeseed sightseeing rapeseed remediation of cadmium pollution rapeseed oil fodder vegetables

Effect of Ti Additions on Mechanical and Thermodynamic Properties of W-Ti Alloys: A First-principles Study

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 246-257页

作者： ZHANG jian NIE Wei HUANG Jin ZHU Ke LIU Ruxia ZHANG Ruizhi LUO Guoqiang shen Qiang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Institute for Carbon Neutrality University of Science and Technology BeijingBeijing 100083China

The mechanical and thermodynamic properties of W-Ti alloys(including W_(15)Ti_(1),W_(14)Ti_(2),W_(12)Ti_(4) and W_(8)Ti_(8) alloys)were investigated by the first-principles approach based on density functional *** results indicate that W-Ti alloys except W_(8)Ti_(8) are thermodynamically *** modulus and hardness of W-Ti alloys are smaller than those of pure tungsten and gradually decrease with increasing Ti ***,their B/G ratios and Poisson's ratios exceed those of pure tungsten,suggesting that the introduction of Ti decreases the mechanical strength while enhancing the ductility of W-Ti *** thermal expansion coefficients for W-Ti alloys all surpass those of pure tungsten,indicating that the introduction of titanium exacerbates the thermal expansion behavior of W-Ti ***,elevated pressure has the capacity to suppress the thermal expansion tendencies in titanium-doped tungsten *** study offers theoretical insights for the design of nuclear materials by exploring the mechanical and thermodynamic properties of W-Ti alloys.

关键词： first-principles mechanical properties thermodynamic properties tungsten-titanium alloys

Pulmonary vein tachycardia after pulmonary vein isolation in patients with atrial fibrillation

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Chinese Medical Journal 2006年第7期119卷 551-556页

作者： MA chang-shen DONG jian-zeng LIU Xing-peng LONG De-yong FANG Dong-ping HU Fu-li YU Rong-hui TANG Ri-bo HAO Peng LU Chun-shan Department of Cardiology Beijing Anzhen Hospital CapitalUniversity of Medical Sciences Beijing 100029 China

Background Pulmonary vein （PV） isolation has been developed to treat patients with atrial fibrillation （AF）, and the electrophysiological endpoint of PV isolation is the disappearance or dissociation of pulmonary vein potentials （PVPs）. Pulmonary vein tachycardia （PVT） is the dissociated PV rhythm with a rapid rate. However, the characteristics and significance of PVT after pulmonary vein isolation in patients with AF remains unclear. Methods From June 2003 to June 2005, a total of 285 consecutive patients with drug refractory AF were included in this study, and they underwent segmental pulmonary vein ablation （SPVA） or circumferential pulmonary vein ablation （CPVA）. PV isolation was the initial endpoint for both approaches with documenting disappearance or dissociation of PVPs. PVT was characterized as dissociated activities within PVs with a circle length （CL） of 〈300 ms, and was classified into organized PVT or disorganized PVT according to the variance of CL. Systematic follow-up was conducted after initial procedures. Continuous variables were analyzed by Student＇s t test and categorical variables were analyzed by chi-square test. Results Three hundred and fifteen PVs were ablated in 85 patients underwent SPVA approach, 400 circular lesions surrounding ipsilateral PVs （including 790 PVs） were produced in the rest of 200 patients received CPVA approach. Electrical isolation was achieved in all of these PVs. Of these, PVPs were abolished in 89.8% （992/1105） of the ablated PVs, dissociated PV rhythms were documented in the rest 10.2 % （113/1105） of the treated PVs. Among the 113 dissociated PV rhythms, 28 met the criteria of PVT with mean CL of （155±43） ms （2 PYTs in 2 patients received SPYA, 26 PYTs in 18 patients underwent CPVA）. PVT was more frequently documented in patients underwent CPVA approach [9.0% （18/200） vs 2.3% （2/85）, P=0.04]. During the 6-month follow-up, it was indicated that no significant difference existed in AF free rate between patients wi

关键词： atrial fibrillation pulmonary vein tachycardia

国家间战争根源分析——解读《人、国家与战争:一种理论分析》

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苏州教育学院学报 2010年第2期27卷 91-94页

作者：沈长剑厦门大学公共事务学院福建厦门361005

肯尼思·N·华尔兹在其《人、国家与战争:一种理论分析》一书中,提出了战争根源的综合因素说。认为人的本性和行为、国家制度的不健全、世界无政府状态的存在,是导致各种类型战争的三种不同层次的因素。开创了国际关系研究中的层次分析... 详细信息

肯尼思·N·华尔兹在其《人、国家与战争:一种理论分析》一书中,提出了战争根源的综合因素说。认为人的本性和行为、国家制度的不健全、世界无政府状态的存在,是导致各种类型战争的三种不同层次的因素。开创了国际关系研究中的层次分析,尤其是关于国际体系性质的分析反映了当代国际关系理论的基本发展趋势。

关键词：人性国家国际体系

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罗伯特·吉尔平的国际关系理论变迁

四川理工学院学报（社会科学版） 2010年第4期25卷 23-27页

作者：沈长剑厦门大学公共事务学院福建厦门361005

在当前西方学术界,用政治经济学的方法来研究国际关系非常流行,罗伯特·吉尔平当属佼佼者。从全球政治经济学(GPE)产生的时代背景,全球政治经济学研究的理论主题,以及这种超越引起什么改变为论述的构架来诠释吉尔平从国际政治经济学(IPE... 详细信息

在当前西方学术界,用政治经济学的方法来研究国际关系非常流行,罗伯特·吉尔平当属佼佼者。从全球政治经济学(GPE)产生的时代背景,全球政治经济学研究的理论主题,以及这种超越引起什么改变为论述的构架来诠释吉尔平从国际政治经济学(IPE)到全球政治经济学的国际关系理论变迁的实质。

关键词：吉尔平 IPE GPE 国际关系理论变迁

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巧权力与领导艺术的完善

辽东学院学报（社会科学版） 2010年第4期12卷 13-17页

作者：沈长剑厦门大学公共事务学院福建厦门361005

领导与权力相关,但并不是所有权力关系都等同于领导。实际上,有效的领导要求综合采用软硬权力技巧,即巧权力。不同环境要求不同比例的软硬权力。领导者需要有足够的管理技巧,确保建立适当体系,能够提供良好决策和高效执行所需的信息。... 详细信息

领导与权力相关,但并不是所有权力关系都等同于领导。实际上,有效的领导要求综合采用软硬权力技巧,即巧权力。不同环境要求不同比例的软硬权力。领导者需要有足够的管理技巧,确保建立适当体系,能够提供良好决策和高效执行所需的信息。高效的领导者可通过创建并维护设计得当的体系来管理和塑造环境,根据对环境的理解成功综合运用软硬权力,实施巧权力领导。

关键词：领导者巧权力领导

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang Xin Liu jian Zhang Ya Gao Shuyue Li Cui chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： shengyang Zhou Ting Li Wei Zhang jian Wu Hui Hong Wei Quan Xinyu Qiao Chun Cui Chenmeng Qiao Weijiang Zhao Yanqin shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

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100μm大晶粒多晶硅薄膜的铝诱导法制备

功能材料 2010年第3期41卷 453-456页

作者：唐正霞沈鸿烈解尧鲁林峰江枫沈剑沧南京航空航天大学材料科学与技术学院江苏南京210016 南京大学物理学系固体微结构物理国家重点实验室江苏南京210093

以Corning Eagle 2000玻璃为衬底,用磁控溅射法制备了glass/a-Si/Si O2/Al叠层结构,于Ar气保护下退火,制备了具有很强的(111)择优取向,最大晶粒尺寸达100μm的铝诱导晶化多晶硅薄膜。研究结果表明,非晶硅的氧化时间越长,所制备的多晶硅... 详细信息

以Corning Eagle 2000玻璃为衬底,用磁控溅射法制备了glass/a-Si/Si O2/Al叠层结构,于Ar气保护下退火,制备了具有很强的(111)择优取向,最大晶粒尺寸达100μm的铝诱导晶化多晶硅薄膜。研究结果表明,非晶硅的氧化时间越长,所制备的多晶硅晶粒尺寸越大,当氧化时间达约47h后,再延长氧化时间对薄膜性能的影响不明显。还发现退火温度越高,晶粒越小,但是反应速率越快。

关键词：薄膜多晶硅铝诱导晶化氧化时间