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Cortical evoked potential changes in a rat model of acute ischemic stroke Detection of somatosensory evoked potential and motor evoked potential

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Neural Regeneration Research 2010年第7期5卷 550-554页

作者： yang shao Department of Neurology Xiangya Hospital of Central South University Changsha 410008 Hunan Province China

BACKGROUND： Studies have shown that latency changes of some elements in a somatosensory evoked potential （SEP） and motor evoked potential （MEP） can reflect electrical activity of cerebral cortical neurons and conduction of white matter nerve fibers. However, there is a paucity of information regarding the dynamic observation of SEP and MEP following cerebral ischemic injury. OBJECTIVE： To explore SEP and MEP changes following acute ischemic stroke, and investigate the role of evoked potentials in monitoring brain function in stroke. DESIGN, TIME AND SETTING： A randomized, controlled, animal experiment was performed at the Chongqing Key Laboratory of Neurology, Affiliated Hospital of Chongqing Medical University from September 2007 to August 2008. MATERIALS＂ Hydrogen blood flow detector was purchased from Soochow University Medical Instrument Co., China, and Power lab system was purchased from AD Instruments, Inc., USA. METHODS A total of 36 healthy, adult, male, Sprague Dawley rats were randomly assigned to four groups （n = 9）, including three ischemia groups （12, 24 and 72 hours of ischemia） and a sham-surgery group. The rat model of acute ischemic stroke was established by middle cerebral artery occlusion （MCAO） in the left hemisphere. MAIN OUTCOME MEASURES＂ SEP and MEP of the left limbs were detected, and cerebral blood flow was measured by the hydrogen cleaning method. RESULTS： The latency of positive wave 1 （P1）, negative wave 1 （N1） and positive wave 2 （P2） waves in SEP, and latency of negative wave 1,2 （N1, N2） waves in MEP were significantly prolonged with increasing ischemic duration following MCAO （P 〈 0.01）, but cerebral blood flow was significantly decreased （P 〈 0.05, or P 〈 0.01）. CONLUSION： Ischemic stroke prolongs the latency of SEP waves （P1, N1, P2） and MEP waves （N1, N2）, and cerebral cortical evoked potential may correlate with cerebral blood flow changes. This indicates that SEP and MEP can be used to evaluate brain function following acute isch

关键词： somatosensory evoked potential motor evoked potential latency cerebral blood flow brain function acute ischemic stroke neural regeneration

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Optimal Matching Analysis of Net Buoyancy and Pitching Angle for Underwater Gliders

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China Ocean Engineering 2022年第5期36卷 697-706页

作者： yang Ming LIANG Yan WANG Yan-hui yang shao-qiong Key Laboratory of Mechanism Theory and Equipment Design of Ministry of Education School of Mechanical EngineeringTianjin UniversityTianjin 300350China The Joint Laboratory of Ocean Observing and Detection Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China

Control parameter optimization is an efficient way to improve the endurance of underwater gliders(UGs),which influences their gliding efficiency and energy *** paper analyzes the optimal matching between the net buoyancy and the pitching angle and proposes a segmented control strategy of *** optimization of this strategy is established based on the gliding range model of UG,which is solved based on the approximate model,and the variations of the optimal control parameters with the hotel load are *** optimization results indicate that the segmented control strategy can significantly increase the gliding range when the optimal matching between the net buoyancy and the pitching angle is reached,and the increase rate is influenced by the hotel *** gliding range of the underwater glider can be increased by 10.47%at a hotel load of 0.5 *** optimal matching analysis adopted in this study can be applied to other UGs to realize endurance improvement.

关键词： optimal matching analysis underwater glider approximate model technology gliding range model

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Does chemical index of alteration(CIA) reflect silicate weathering and monsoonal climate in the Changjiang River basin?

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Chinese Science Bulletin 2012年第10期57卷 1178-1187页

作者： shao JingQing yang ShouYe State Key Laboratory of Marine Geology Key Laboratory of Yangtze River Water Environment Ministry of Education Tongji UniversityShanghai 200092 China

Chemical weathering of continental silicates significantly influences global climate change,earth surface processes,material cy-cling and oceanic chemical *** to quantitatively reconstruct chemical weathering history has become an important issue in global change *** index of alteration(CIA) has been widely used as a quantitative indicator for estimating the degree of silicate ***,its method of calculation and the limitations of its application are not well *** this study,we calculated CIA values from suspended particulate matter collected from the mainstream and major tributaries of the Changjiang *** values yielded considerable variations at different temporal and spatial *** average CIA values increased from the upper to middle-lower reaches,and were lower in the suspended samples taken during the flood than in the dry *** spatial variation in the CIA is predominantly controlled by basinal monsoon *** contrast,the temporal varia-tion in the Changjiang River basin is controlled mainly by the changing provenance of suspended samples in relation to the shift of the precipitation *** CIA probably indicates the integrated weathering history in the river basin,and thus,cannot be used as a reliable proxy of instantaneous chemical ***,the calculation method and hydrodynamic sorting also influence the CIA ***,caution should be taken when using the CIA as a proxy for studying chemical weathering from different regions.

关键词：化学蚀变指数长江流域季风气候 CIA 硅酸盐盐风化化学风化全球气候变化

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Different frequencies of repetitive transcranial magnetic stimulation combined with local injection of botulinum toxin type A for post-stroke lower limb spasticity:study protocol for a prospective,single-center,non-randomized,controlled clinical trial

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Neural Regeneration Research 2022年第11期17卷 2491-2496页

作者： yang shao yang yang Yong-Xin Sun Ai-Hua Xu Department of Rehabilitation Medicine the First Affiliated Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

No definite consensus has currently been reached regarding the safety and efficacy of low-or high-frequency repetitive transcranial magnetic stimulation in the treatment of post-stroke muscle *** latest research indicates that when combined with local injections of botulinum toxin type A,it is more effective on post-stroke muscle spasticity than local injections of botulinum toxin type A *** designed a prospective,single-center,non-randomized,controlled clinical trial to investigate the safety and effica cy of different frequencies of repetitive transcranial magnetic stimulation combined with local injections of botulinum toxin type A in treating post-stroke lower limb muscle spasticity to determine an optimal therapeutic *** trial will enroll 150 patients with post-stroke muscle spasticity admitted to the Department of Rehabilitation Medicine at the First Affiliated Hos pital of China Medical Unive *** enrolled patients will undergo ro utine rehabilitation training and will be divided into five groups in-30 per group) according to the particular area of cerebral infa rction and treatment methods.G roup A:Patients with massive cerebral infarction will be given local injections of botulinum toxin type A and low-frequency(1 Hz)repetitive transcranial magnetic stimulation on the contralate ral side;G roup B:Patients with non-massive cerebral infarction will be given local injections of botulinum toxin type A and high-frequency(10-20 Hz) re petitive transcranial magnetic stimulation on the affected side;G roup C:Patients with massive/non-massive cerebral infarction will be given local injections of botulinum toxin type A;G roup D:Patients with massive cerebral infarction will be given low-frequency(1 Hz) repetitive transcranial magnetic stimulation on the contralate ral side;and G roup E:Patients with non-massive cerebral infa rction will be given high-frequency(10-20 Hz) repetitive transcranial magnetic stimulation on the affected ***

关键词： Botulinum toxin type A exercise lower limbs muscle spasticity neural regeneration rehabilitation training repetitive transcranial magnetic stimulation stroke

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Enhanced photocatalytic performance of iron oxides@HTCC fabricated from zinc extraction tailings for methylene blue degradation:Investigation of the photocatalytic mechanism

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International Journal of Minerals,Metallurgy and Materials 2023年第12期30卷 2364-2374页

作者： yang Xue Xiaoming Liu Na Zhang yang shao Chunbao(Charles)Xu State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid Wastes National Laboratory of Mineral MaterialsSchool of Materials Science and TechnologyChina University of GeosciencesBeijing 100083China Department of Chemical&Biochemical Engineering Western UniversityLondonON N6A 5B9Canada

Photocatalytic processes are efficient methods to solve water contamination problems,especially considering dyeing wastewater ***,high-efficiency photocatalysts are usually very expensive and have the risk of heavy metal ***,an iron oxides@hydrothermal carbonation carbon(HTCC)heterogeneous catalyst was prepared by our group through co-hydrothermal treatment of carbohydrates and zinc extraction tailings of converter ***,the catalytic performance of the iron oxides@HTCC was verified by a nonbiodegradable dye,methylene blue(MB),and the catalytic mechanism was deduced from theoretical simulations and spectroscopic *** iron oxides@HTCC showed an excellent synergy between photocatalysis and Fenton-like *** visible-light illumination,the iron oxides@HTCC could be excited to generate electrons and holes,reacting with H_(2)O_(2)to produce·OH radicals to oxidize and decompose organic *** removal efficiency of methylene blue over iron oxides@HTCC at 140 min was 2.86 times that of *** enhanced catalytic performance was attributed to the advantages of iron oxides modification:(1)promoting the excitation induced by photons;(2)improving the charge ***,the iron oxides@HTCC showed high catalytic activity in a wide pH value range of 2.3-10.4,and the MB removal efficiency remained higher than 95% after the iron oxides@HTCC was recycled 4 *** magnetically recyclable iron oxides@HTCC may provide a solution for the treatment of wastewater from the textile industry.

关键词： photocatalysis photo-Fenton reaction methylene blue degradation tailings utilization

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A New Approach for Controlling Chaos Based on Direct Optimizing Predictive Control

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Communications in Theoretical Physics 2006年第3期45卷 473-476页

作者： LI Dong-Mei yang shao-Zhen School of Economy and Management Hebei University of Science and Technology Shijiazhuang 050018 China

We introduce the predictive control theory into predictive control algorithm based on a neural network model the study of chaos control and propose a direct optimizing The proposed control system stabilizes the chaotic motion in an unknown chaotic system onto the desired target trajectory. Compared with the existing similar algorithms, the proposed control system has faster response, so it requires much shorter time for the stabilization of the chaotic systems. The proposed approach can control hyperchaos and the algorithm is simple. The convergence of the control algorithm and the stability of the control system can be guaranteed. The theoretic analysis and simulations demonstrate the effectiveness of the algorithm.

关键词： vchaos control predictive control chaotic system neural networks

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A 2D Mapping Method Based on Virtual Laser Scans for Indoor Robots

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International Journal of Automation and computing 2021年第5期18卷 747-765页

作者： Xu-yang shao Guo-Hui Tian Ying Zhang School of Control Science and Engineering Shandong UniversityJinan 250061China

The indoor robots are expected to complete metric navigation tasks safely and efficiently in complex environments, which is the essential prerequisite for accomplishing other high-level operation tasks. 2 D occupancy grid maps are sufficient to support the robots in avoiding all obstacles in the environments during navigation. However, the maps based on normal laser scans only reflect a horizontal slice of the environment, which may cause the problem of some obstacles missing or misinterpreting their exact boundaries,thereby threatening the safety and efficiency of robot navigation. This paper presents a 2 D mapping method based on virtual laser scans to provide a more comprehensive representation of obstacles for indoor robot navigation. The resulting maps can accurately represent the top-down projected contours of all obstacles no matter where their vertical positions are. The virtual laser scans are initially generated from raw data of an RGB-D camera based on the filtering, projection, and polar-coordinate scanning. The scans are fed directly to the laser-based simultaneous localization and mapping(SLAM) algorithms to update the current map and robot position. Two auxiliary strategies are proposed to further improve the quality of maps by reducing the impact of the narrow field of view and the blind zone of the RGB-D camera on the observations. In this paper, the improved virtual laser generation method makes the extracted 2 D observations fit the laser-based SLAM algorithms, and two auxiliary strategies are novel ways to improve map quality. The generated maps can reflect the comprehensive obstacle information in indoor environments with good accuracy. The comparative experiments are carried out based on four simulation scenarios and three real-world scenarios to prove the effectiveness of our 2 D mapping method.

关键词： 2D mapping indoor robots virtual laser mapping auxiliary strategies safe navigation

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Eat at the right time: Regulation of ER-phagy receptors in plant response to environmental stresses

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Molecular Plant 2024年第2期17卷 236-239页

作者： yang shao Jiaqi Sun Huanquan Zheng The Key Laboratory of Plant Development and Environmental Adaptation Biology Ministry of EducationSchool of Life SciencesShandong UniversityQingdao 266237China Department of Biology McGill UniversityMontrealQC H3A 1B1Canada

The endoplasmic reticulum(ER)is a cellular factory for biosynthesis of proteins and *** accommodate a wide array of biosynthetic demands in responses to environmental stresses,the plant ER remodels to maintain a structural and functional homeostasis.A key process facilitating this balance is selective autophagy of the ER(ER-phagy),where malfunctioned ER is recognized,engulfed by autophagosomes,and then delivered to the vacuole for degradation.

关键词： maintain accommodate function

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LSB steganalysis of speech data based on distance measure and ML decision

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The Journal of China Universities of Posts and Telecommunications 2007年第3期14卷 103-107页

作者： DENG Zong-yuan shao Xi yang Zhen Institute of Signal and Information Processing Nanjing University of Postsand Telecommunications Nanjing 210003 China

Steganalysis can be used to classify an object whether or not it contains hidden information. In this article, is presented, a novel approach to detect the presence of least significant bit（LSB） steganographic messages in the voice secure communication system. A distance measure, which has proven to be sensitive to LSB steganography by analysis of variance （ANOVA）, is denoted to estimate the difference between the host signal and the stego signal. Then an maximum likelihood （ML） decision is combined to form the classifier. Statistical experiments show that the proposed approach has a highly accurate rate and low computational complexity.

关键词： speech signal processing LSB steganography steganalysis ML decision

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Fabrication and Photoelectrochemical Properties of[Ru(bpy)_2dppz]^(2+) on ITO Electrode Associated with the Oxidation of Guanine

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Chemical Research in Chinese Universities 2010年第4期26卷 649-655页

作者： GUO Qing-yu LI Hong yang Hui-yi shao Jiang-yang Key Lab of Technology on Electrochemical Energy Storage and Power Generation in Guangdong Universities School of Chemistry and Environment South China Normal University Guangzhou 510006 P. R. China

Electrochemical assembly of [Ru（bpy）2dppz]^2＋{bpy=2,2＇-bipyridine, dppz=dipyrido[3,2-a：＂2＇,3＇-c]phenazine} on an ITO electrode in the presence of guanine and photoelectroehemical properties of the assembled layer were investigated. It has been found that [Ru（bpy）2dppz]^3＋/2＋ can be assembled onto the ITO electrode by the method of repetitive voltammetric sweeping, and the assembly is enhanced by guanine. The peak currents of prewaves increase linearly up to a guanine concentration of 0.25 mmol/L. More importantly, upon illumination with 470 nm light source and at an applied potential of 0.2 V, cathodic current for the fabricated layer on the ITO electrode indicate a linear enhancement with the rise of guanine concentration. Meanwhile, [Ru（bpy）2dppz]^2＋ can be served as an excellent mediator to prompt the oxidation of guanine, and the mediated peak current increases linearly with added guanine concentration from 0.01 to 0.25 mmol/L. In addition, the assembly mechanism of [Ru（bpy）2dppz]^2＋ on the ITO electrode associated with the oxidation of guanine and the assistance of light irradiation were discussed.

关键词： Polypyridvl ruthenium(II) complex Guanine ITO Assembly Photoelectrochemistrv

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