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Correlation Composition Awareness Model with Pair Collaborative Localization for Iot Authentication and Localization

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Computers, Materials & Continua 2024年第4期79卷 943-961页

作者： Kranthi Alluri s.Gopikrishnan school of Computer science and Engineering VIT-AP UniversityAmaravathiAndhra Pradesh522241India

secure authentication and accurate localization among Internet of things(Iot)sensors are pivotal for the functionality and integrity of Iot *** authentication and localization are intricate and symbiotic,impacting both the security and operational functionality of Iot ***,accurate localization and lightweight authentication on resource-constrained Iot devices pose several *** overcome these challenges,recent approaches have used encryption techniques with well-known key ***,these methods are inefficient due to the increasing number of data breaches in their localization *** proposed research efficiently integrates authentication and localization processes in such a way that they complement each other without compromising on security or *** proposed framework aims to detect active attacks within Iot networks,precisely localize malicious Iot devices participating in these attacks,and establish dynamic implicit authentication *** integrated framework proposes a Correlation Composition Awareness(CCA)model,which explores innovative approaches to device correlations,enhancing the accuracy of attack detection and ***,this framework introduces the Pair Collaborative Localization(PCL)technique,facilitating precise identification of the exact locations of malicious Iot *** address device authentication,a Behavior and Performance Measurement(BPM)scheme is developed,ensuring that only trusted devices gain access to the *** work has been evaluated across various environments and compared against existing *** results prove that the proposed methodology attains 96%attack detection accuracy,84%localization accuracy,and 98%device authentication accuracy.

关键词： sensor localization Iot authentication network security data accuracy precise location access control security framework

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Viral and nonviral nanocarriers for in vivo CRIsPR-based gene editing

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Nano Research 2024年第10期17卷 8904-8925页

作者： Zhongyuan Guo Audrey t.Zhu Ronnie H.Fang Liangfang Zhang Aiiso Yufeng Li Family Department of Chemical and Nano Engineering University of California San DiegoLa JollaCA 92093USA Division of Host-Microbe systems and therapeutics Department of PediatricsUniversity of California San DiegoLa JollaCA 92093USA

the continued development of clustered regularly interspaced short palindromic repeats(CRIsPR)technology has the potential to greatly impact clinical medicine,particularly for disease diagnosis and *** high demand for the in vivo delivery of CRIsPR-based therapies,significant challenges *** include rapid degradation by enzymes,inefficient disease site targeting,and the risk of undesired off-target *** platforms,with their tailorable properties,have been engineered to efficiently package CRIsPR payloads in various formats,including as plasmid DNA,mRNA,and ribonucleoprotein complexes,for in vivo *** them,recombinant adeno-associated viruses,virus-like particles,and lipid nanoparticles have displayed exceptional *** review will discuss the development of these and other nanocarriers for in vivo CRIsPR-based genome editing.

关键词： clustered regularly interspaced short palindromic repeats(CRIsPR) in vivo gene editing nanocarriers recombinant adeno-associated viruses(rAAVs) virus-like particle(VLP) lipid nanoparticle(LNP)

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Astrocytes dynamically regulate the blood-brain barrier in the healthy brain

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Neural Regeneration Research 2024年第4期19卷 709-710页

作者： AgnėPociūtė Augustas Pivoriūnas Alexei Verkhratsky Department of stem Cell Biology State Research Institute Centre for Innovative MedicineVilniusLithuania Faculty of Biology Medicine and HealthThe University of ManchesterManchesterUK Achucarro Centre for Neuroscience IKERBASQUEBasque Foundation for ScienceBilbaoSpain Department of Forensic Analytical toxicology School of Forensic MedicineChina Medical UniversityShenyangLiaoning ProvinceChina

the blood-brain barrier(BBB)(discovered and defined by Max Lewandowsky and Lina stern,and not,as it is universally,and yet erroneously believed,by Paul Ehrlich(Verkhratsky and Pivoriunas,2023))that separates the nervous system from the circulation is evolutionarily conserved from arthropods to *** primeval BBB of the invertebrates and some early vertebrates was made solely by glial cells and secured(in invertebrates)by septate junctions.

关键词： Ehrlich barrier blood

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Conservation laws,Lie symmetries,self adjointness,and soliton solutions for the selkov–schnakenberg system

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Communications in theoretical Physics 2024年第2期76卷 29-44页

作者： Kashif Ali Aly R seadawy syed t R Rizvi Noor Aziz Department of Mathematics COMSATS University IslamabadLahore CampusPakistan Mathematics Department Faculty of ScienceTaibah UniversityAl-Madinah Al-Munawarah41411Saudi Arabia

In this article,we explore the famous selkov–schnakenberg(ss)system of coupled nonlinear partial differential equations(PDEs)for Lie symmetry analysis,self-adjointness,and conservation ***,miscellaneous soliton solutions like dark,bright,periodic,rational,Jacobian elliptic function,Weierstrass elliptic function,and hyperbolic solutions of the ss system will be achieved by a well-known technique called sub-ordinary differential *** these results are displayed graphically by 3D,2D,and contour plots.

关键词： selkov-schnakenberg system Lie symmetry analysis conservation laws adjointness integrability

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Big data challenge for monitoring quality in higher education institutions using business intelligence dashboards

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Journal of Electronic science and technology 2024年第1期22卷 25-41页

作者： Ali sorour Anthony s.Atkins Faculty of Digital TechnologyInnovationand BusinessStaffordshire UniversityStoke-on-TrentST42DEUnited Kingdom

As big data becomes an apparent challenge to handle when building a business intelligence(BI)system,there is a motivation to handle this challenging issue in higher education institutions(HEIs).Monitoring quality in HEIs encompasses handling huge amounts of data coming from different *** paper reviews big data and analyses the cases from the literature regarding quality assurance(QA)in *** also outlines a framework that can address the big data challenge in HEIs to handle QA monitoring using BI dashboards and a prototype dashboard is presented in this *** dashboard was developed using a utilisation tool to monitor QA in HEIs to provide visual representations of big *** prototype dashboard enables stakeholders to monitor compliance with QA standards while addressing the big data challenge associated with the substantial volume of data managed by HEIs’QA *** paper also outlines how the developed system integrates big data from social media into the monitoring dashboard.

关键词： Big data Business intelligence(BI) Dashboards Higher education(HE) Quality assurance(QA) social media

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Bile acid metabolism and signaling in health and disease:molecular mechanisms and therapeutic targets

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signal transduction and targeted therapy 2024年第5期9卷 2014-2064页

作者： Joshua s.Fleishman sunil Kumar Department of Pharmaceutical sciences College of Pharmacy and Health SciencesSt.John’s UniversityQueensNYUSA

Bile acids,once considered mere dietary surfactants,now emerge as critical modulators of macronutrient(lipid,carbohydrate,protein)metabolism and the systemic pro-inflammatory/anti-inflammatory *** acid metabolism and signaling pathways play a crucial role in protecting against,or if aberrant,inducing cardiometabolic,inflammatory,and neoplastic conditions,strongly influencing health and *** curative treatment exists for any bile acid influenced disease,while the most promising and well-developed bile acid therapeutic was recently rejected by the ***,we provide a bottom-up approach on bile acids,mechanistically explaining their biochemistry,physiology,and pharmacology at canonical and non-canonical *** this mechanistic model of bile acids,we explain how abnormal bile acid physiology drives disease pathogenesis,emphasizing how ceramide synthesis may serve as a unifying pathogenic feature for cardiometabolic *** provide an in-depth summary on pre-existing bile acid receptor modulators,explain their shortcomings,and propose solutions for how they may be ***,we rationalize novel targets for further translational drug discovery and provide future *** than dismissing bile acid therapeutics due to recent setbacks,we believe that there is immense clinical potential and a high likelihood for the future success of bile acid therapeutics.

关键词： metabolism rejected shortcomings

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Evaluation of a software positioning tool to support sMEs in adoption of big data analytics

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Journal of Electronic science and technology 2024年第1期22卷 13-24页

作者： Matthew Willetts Anthony s.Atkins Faculty of Digital TechnologyInnovationand BusinessStaffordshire UniversityStoke-on-TrentST42DEUnited Kingdom

Big data analytics has been widely adopted by large companies to achieve measurable benefits including increased profitability,customer demand forecasting,cheaper development of products,and improved stock *** and medium sized enterprises(sMEs)are the backbone of the global economy,comprising of 90%of businesses ***,only 10%sMEs have adopted big data analytics despite the competitive advantage they could *** research has analysed the barriers to adoption and a strategic framework has been developed to help sMEs adopt big data *** framework was converted into a scoring tool which has been applied to multiple case studies of sMEs in the *** paper documents the process of evaluating the framework based on the structured feedback from a focus group composed of experienced *** results of the evaluation are presented with a discussion on the results,and the paper concludes with recommendations to improve the scoring tool based on the proposed *** research demonstrates that this positioning tool is beneficial for sMEs to achieve competitive advantages by increasing the application of business intelligence and big data analytics.

关键词： Big data analytics Evaluation small and medium sized enterprises (sMEs) strategic framework

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A study on the transmission Dynamics of the Omicron Variant of COVID-19 Using Nonlinear Mathematical Models

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Computer Modeling in Engineering & sciences 2024年第6期139卷 2265-2287页

作者： s.Dickson s.Padmasekaran Pushpendra Kumar Kottakkaran sooppy Nisar Hamidreza Marasi Department of Mathematics Periyar UniversitySalemTamilnadu636011India Faculty of Engineering and Natural sciences Istanbul Okan UniversityIstanbulTurkey Department of Mathematics College of Science and Humanities in AlkharjPrince Sattam Bin Abdulaziz UniversityAlkharj11942Saudi Arabia Department of Applied Mathematics Faculty of MathematicsStatistics and Computer ScienceUniversity of TabrizTabrizIran

this research examines the transmission dynamics of the Omicron variant of COVID-19 using sEIQIcRVW and sQIRV models,considering the delay in converting susceptible individuals into infected *** significant delays eventually resulted in the pandemic’s *** ensure the safety of the host population,this concept integrates quarantine and the COVID-19 *** investigate the stability of the proposed *** fundamental reproduction number influences stability *** to our findings,asymptomatic cases considerably impact the prevalence of Omicron infection in the *** real data of the Omicron variant from Chennai,tamil Nadu,India,is used to validate the outputs.

关键词： Omicron local stability reproduction number steady states global stability

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transjugular intrahepatic portosystemic shunt for recompensating decompensated cirrhosis?

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World Journal of Gastroenterology 2024年第20期30卷 2621-2623页

作者： Dimitrios s Karagiannakis Academic Department of Gastroenterology and Hepatology Medical School of National and Kapodistrian University of AthensGeneral Hospital of Athens“Laiko”Athens 11527Greece

transjugular intrahepatic portosystemic shunt(tIPs)is a medical procedure that has been used to manage variceal bleeding and ascites in patients with *** can prevent further decompensation and improve the survival of high-risk decompensated *** research indicates that tIPs could increase the possibility of recompensation of decompensated cirrhosis when it is combined with adequate suppression of the causative factor of liver ***,the results of the studies have been based on retrospective analysis,and further validation is required by conducting randomized controlled *** this context,we highlight the limitations of the current studies and emphasize the issues that must be addressed before tIPs can be recommended as a potential recompensating tool.

关键词： Decompensated cirrhosis Liver recompensation Baveno VII transjugular intrahepatic portosystemic shunt

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Elevation transition of aquatic insects closely matches a thermal feature in the Yungas of Northwestern Argentina

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Journal of Mountain science 2024年第2期21卷 433-448页

作者： Alexandra BUItRAGO-GUACANAME Carlos MOLINERI Andrés LIRA-NORIEGA Daniel Andrés DOs sANtOs Neotropical Biodiversity Institute(CONICEt-UNt) UNT-DomesHorco Molle S/N4107 TucumánArgentina CONACYt Research Fellow Network of Advanced Molecular StudiesInstitute of Ecology A.COld Road to Coatepec 351El HayaCP 91073XalapaVeracruzMexico Biostatistics Chair Faculty of Natural Sciences and IMLNational University of TucumánSan Miguel de TucumánMiguel Lillo 2054000 TucumánArgentina

temperature is a key factor that shapes the distribution of *** knowledge about how species respond to temperature is relevant to devise strategies for addressing the impacts of climate *** insects are particularly vulnerable to climate change,yet there is still much to learn about their ecology and *** the Yungas ecoregion of Northwestern Argentina,cold-and warm-adapted species of the orders Ephemeroptera,Plecoptera,and trichoptera(EPt)are segregated by *** modeled the ecological niche of south American EPt species in this region using available data and projected their potential distribution in geographic *** were grouped based on their ecogeographic similarity,and we analyzed their replacement pattern along elevation gradients,focusing on the ecotone where opposing thermal preferences *** this interface,we identified critical points where the combined incidence of cold and warm assemblages maximizes,indicating a significant transition *** found that the Montane Cloud Forest holds the interface,with a particularly greater suitability at its lower *** main axis of the interface runs in a N-s direction and falls between 14°C-16°C mean annual *** probability of a particular location within a basin being classified as part of the interface increases as Kira’s warmth index approaches a score around *** the interface is critical for defining the thermal limits of species distribution and designing biomonitoring *** in the location of thermal constants related to mountainous ecotones may cause vertical displacement of aquatic insects and vegetation *** have recognized significant temperature thresholds that serve as indicators of suitability for the *** global warming is anticipated to shift these indicators,we suggest using them to monitor the imprints of climate change on mountain ecosystems.

关键词： Austral Yungas Ecological Niche Model Ephemeroptera Kira’s warmth index Plecoptera trichoptera

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