检索结果-南通市图书馆

Mechanism of reinforcement of jointed masses by rock bolts

在线全文

学校读者我要写书评

暂无评论

Mechanism of reinforcement of jointed masses by rock bolts

International Conference on Anchoring & Grouting Towards the New Century

作者： s.sakurai Hiroshima Institute of Technology HiroshimaJapan

＜正＞In order to clarify the support mechanism of rock bolts installed in a jointed rock mass for stabilizing a tunnel excavated in it,laboratory experiments have been *** this paper,the laboratory experimental results are shown,and the supporting mechanism of rock bolts is ***,a numerical modeling representing the function of reinforcement by rock bolts on jointed rock masses is proposed.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

开挖边坡中位移测量成果的整理解析

人民长江 1989年第5期20卷 48-54页

作者： s.sakurai 李迪

一、前言即使采用复杂的数值分析方法(为有限元法),对开挖边坡的变形性状的预测也常常和开挖期间实际观察到的情况不同。这主要是因为在预测边坡性状中的地质条件和地基材料的力学性质很难正确地估计。为克服这种困难,要进行现场测量并... 详细信息

一、前言即使采用复杂的数值分析方法(为有限元法),对开挖边坡的变形性状的预测也常常和开挖期间实际观察到的情况不同。这主要是因为在预测边坡性状中的地质条件和地基材料的力学性质很难正确地估计。为克服这种困难,要进行现场测量并根据对测量成果的整理解析来监视边坡的稳定性。

关键词：开挖边坡常数变形模式数学滑动面钻孔倾斜仪力学模型位移测量最大剪应变反分析法初始应力

Advanced Control scenario of High-Performance steady-state Operation for JT-60 superconducting Tokamak

在线全文

学校读者我要写书评

暂无评论

Plasma science and Technology 2004年第3期6卷 2281-2285页

作者： H.Tamai G.Kurita M.Matsukawa K.Urata s.sakurai K.Tsuchiya A.Morioka Y.M.Miura K.Kizu Y.Kamada A.sakasai s.Ishida Japan Atomic Energy Research Institute Naka Ibaraki 311-0193 Japan

Plasma control on high-β_N steady-state operation for JT-60 superconductingmodification is discussed. Accessibility to high-β_N exceeding the free-boundary limit isinvestigated with the stabilising wall of reduced-activated ferritic steel and the active feedbackcontrol of the ill-vessel non-axisymmetric field coils. Taking the merit of superconducting magnet,advanced plasma control for steady-state high performance operation could be expected.

关键词： plasma control superconducting tokamak JT-60

static stretching Combined with Conscious slower Breathing May Increase Parasympathetic Activity and Reduce stress in Adult Women

在线全文

学校读者我要写书评

暂无评论

Health 2024年第3期16卷 242-256页

作者： Mami sakurai Yasushi Ikarashi Masahiro Tabuchi Ailing Hu Takuji Yamaguchi Hiroyuki Kobayashi Department of Hospital Administration Juntendo University Graduate School of Medicine Tokyo Japan Department of Beauty & Wellness Professional University of Beauty & Wellness Yokohama Japan Department of Personalized Kampo Medicine Juntendo University Graduate School of Medicine Tokyo Japan

Background: Women are thought to be more susceptible to stress than men in a stressful society, and reducing stress is crucial for women to maintain their health. static stretching (ssT) is applied in various fields to not only increase muscle flexibility but also reduce stress. Additionally, conscious slower breathing (CsB) predominates parasympathetic activity, causing a relaxing effect. These results indicate that combining ssT and CsB may be more useful in reducing stress. However, to the best of our knowledge, the effect of this combination remains unclear. Objective: This study aimed to elucidate the effects of the combination of ssT and CsB on autonomic activity and stress in adult women. Methods: Eleven healthy Japanese adult female participants performed ssT with nonconscious natural breathing for 20 min. The same participants performed ssT in combination with CsB (2 s inspiratory and 4 s expiratory) for 20 min on another day. salivary cortisol and chromogranin A levels were measured before and after stretching as stress markers of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. The coefficient of variation of the R-R interval (CVR-R) and high-frequency component (HF), which reflect parasympathetic nerve activity, and heart rate and low-frequency component (LF)/HF ratio, which reflect sympathetic nerve activity, were measured before, during, and after stretching. Results: ssT decreased cortisol levels but with no significant changes in chromogranin A, heart rate, CVR-R, HF, or LF/HF ratio. The combination of ssT and CsB increased CVR-R and HF levels in addition to decreasing cortisol levels but with no significant changes in chromogranin A, heart rate, or LF/HF levels. Conclusion: These results indicate that the combination of ssT and CsB may increase parasympathetic activity and reduce stress. However, future randomized controlled trials with larger sample sizes should support this conclusion.

关键词： static stretching Conscious slower Breathing Autonomic Activity Heart Rate Variability stress

Inverse relationship between platelet Akt activity and hippocampal atrophy:A pilot case-control study in patients with diabetes mellitus

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第2期12卷 302-313页

作者： Haruhiko Tokuda Takamitsu Hori Daisuke Mizutani Tomoyuki Hioki Kumi Kojima Takashi Onuma Yukiko Enomoto Tomoaki Doi Rie Matsushima-Nishiwaki shinji Ogura Hiroki Iida Toru Iwama Takashi sakurai Osamu Kozawa Department of Metabolic Research Research InstituteNational Center for Geriatrics and GerontologyObu 474-8511Japan Department of Clinical Laboratory National Center for Geriatrics and GerontologyObu 474-8511Japan Department of Pharmacology Gifu University Graduate School of MedicineGifu 501-1194Japan Department of Neurosurgery Gifu University Graduate School of MedicineGifu 501-1194Japan Department of Dermatology Central Japan International Medical CenterMinokamo 505-8510Japan Department of Anesthesiology and Pain Medicine Gifu University Graduate School of MedicineGifu 501-1194Japan Department of Emergency Medicine Faculty of MedicineUniversity of ToyamaToyama 930-0194Japan Department of Emergency and Disaster Medicine Gifu University Graduate School of MedicineGifu 501-1194Japan Research Institute National Center for Geriatrics and GerontologyObu 474-8511Japan

BACKGROUND Akt plays diverse roles in *** is involved in the pathogenesis of type 2 diabetes mellitus(T2DM),which is caused by insulin *** also plays a vital role in human platelet ***,the hippocampus is closely associated with memory and learning,and a decrease in hippocampal volume is reportedly associated with an insulin-resistant phenotype in T2DM patients without *** To investigate the relationship between Akt phosphorylation in unstimulated platelets and the hippocampal volume in T2DM *** Platelet-rich plasma(PRP)was prepared from the venous blood of patients with T2DM or age-matched *** pellet lysate of the centrifuged PRP was subjected to western blotting to analyse the phosphorylation of Akt,p38 mitogen-activated protein(MAP)kinase and glyceraldehyde 3-phosphate dehydrogenase(GAPDH).Phosphorylation levels were quantified by densitometric *** volume was analysed using a voxel-based specific regional analysis system for Alzheimer’s disease on magnetic resonance imaging,which proposes the Z-score as a parameter that reflects hippocampal *** The levels of phosphorylated Akt corrected with phosphorylated p38 MAP kinase were inversely correlated with the Z-scores in the T2DM subjects,whereas the levels of phosphorylated Akt corrected with GAPDH were ***,this relationship was not observed in the control *** These results suggest that an inverse relationship may exist between platelet Akt activation and hippocampal atrophy in T2DM *** findings provide insight into the molecular mechanisms underlying T2DM hippocampal atrophy.

关键词： Akt Platelet Hippocampal atrophy Magnetic resonance imaging Diabetes mellitus

Progress in Physics and Technology Developments for the Modification of JT-60

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plasma science and Technology 2004年第1期6卷 2141-2150页

作者： H.Tamai M.Matsukawa G.Kurita N.Hayashi K.Urata Y.M.Miura K.Kizu K.Tsuchiya A.Morioka Y.Kudo s.sakurai K.Masaki T.suzuki M.Takechi Y.Kamada A.sakasai s.Ishida K.Abe A.Ando T.Cho T.Fujii T.Fujita s.Goto K.Hananda A.Hatayama T.Hino H.Horiike N.Hosogane M.Ichimura Tsuji-Iio s.Itoh M.Katsurai M.Kikuchi A.Kohyama H.Kubo M.Kuriyama M.Matsuoka Y.Miura N.Miya T.Mizuuchi K.Nagasaki H.Ninomiya N.Nishino Y.Ogawa K.Okano T.Ozeki M.saigusa M.sakamoto M.satoh M.shimada R.shimada M.shimizu T.Takagi Y.Takase T.Tanabe K.Toi Y.Ueda Y.Uesugi K.Ushigusa Y.Yagi T.Yamamoto K.Yatsu K.Yoshikawa Japan Atomic Energy Research Institute Naka Ibarahi 311-0193 Japan Tohoku University University of Tsukuba Osaka University Kyushu University Keio University Hokkaido University Tokyo Institute of Technology the University of Tokyo Kyoto University Mie University Hiroshima University Central research Institute of Electric Power Industry Ibaraki University ITER JCT Nagoya University National Institute for Fusion science Kanazawa University National Institute of Advanced Industrial science and Technology

Recent progress in the physics and engineering design study for themodification programme of JT-60 is presented. In order to achieve a steady state high-βplasmaoperation, which is the dominant issue of this programme, physics design for the MHD control and thestability analysis is investigated. Engineering design and the R & D for the superconducting coils,irradiation shield are performed well towards the mission of programme.

关键词： modification of JT-60 physics design technology developments

Nuclear physics with RI Beam Factory

在线全文

学校读者我要写书评

暂无评论

Frontiers of physics 2018年第6期13卷 145-159页

作者： Hiroyoshi sakurai Department of Physics University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan RIKEN Nishina Center for Accelerator-Based Science 2-1 Hirosawa Wako Saitama 351-0198 Japan

Research activities of nuclear physics at Radioactive Isotope Beam Factory over 10 years are reviewed and future directions are also discussed. Conceptual ideas in designing the facility as well as experimental device... 详细信息

关键词： radioactive isotope beams heavy-ion accelerator facility in-flight production experimental devices and techniques storage rings r-process path nuclear waste problems

HER2-positive adenocarcinoma arising from heterotopic pancreas tissue in the duodenum:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2021年第28期27卷 4738-4745页

作者： Yoshifumi s Hirokawa Takashi Iwata Yoshinaga Okugawa Koji Tanaka Hiroyuki sakurai Masatoshi Watanabe Department of Oncologic Pathology Mie University Graduate School of MedicineMie 5148507Japan Cancer Center Aichi Medical UniversityAichi 4801195Japan Department of Genomic Medicine Mie University HospitalMie 5148507Japan Department of surgery IGA City General HospitalMie 5180823Japan Hepato-biliary-pancreatic and Transplant surgery Mie University HospitalMie 5148507Japan

BACKGROUND Adenocarcinoma originating from heterotopic pancreas tissue is a rare ***,to our knowledge,no HER2-positive cases in the duodenum have been reported in the scientific literature nor has the efficacy of trastuzumab treatment for the disease been *** sUMMARY A 65-year-old woman whose clinical diagnosis was unresectable advanced duodenal cancer with HER2 overexpression responded well to trastuzumab *** main tumor in the duodenum reduced *** patient underwent pancreaticoduodenectomy and lymph node dissection.A small number of cancer cells remained in the submucosal layer of the duodenum and pancreas *** histological and immunohistochemical examination,the patient was diagnosed with duodenal adenocarcinoma originating from heterotopic pancreas *** Trastuzumab treatment is effective in HER2-positive adenocarcinoma originating from heterotopic pancreas tissue in the duodenum.

关键词： Heterotopic pancreas tissue Duodenal cancer Human epidermal growth factor receptor 2 Trastuzumab Conversion surgery Case report

Transient hyperphosphatasemia:Possible association with pediatric acute respiratory infection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pediatric Investigation 2021年第2期5卷 94-98页

作者： Yoshihiko sakurai Takafumi Higashiguchi Department of Pediatrics Matsubara Tokushukai HospitalMatsubaraJapan

Importance Acute respiratory infections are quite prevalent in *** hyperphosphatasemia(TH)is defined as the transient elevation of serum alkaline phosphatase(ALP)level,which occurs mainly in infants and children without liver or bone *** no apparent cause has been identified,a possible association of respiratory infections with TH has been reported in the *** In this study,we aimed to investigate the association between TH and respiratory infectious *** We collected the results of biochemical investigations,including ALP level,for a period of 5 years in our *** then examined the patients with transiently elevated ALP levels of>2000 U/*** During the observation period,1501 blood samples were collected from 1097 *** elevation of serum ALP level was observed in 12 *** patients with hyperphosphatasemia,except for one with Fanconi syndrome attributable to the underlying Wilson’s disease,were ageds and were diagnosed with *** of these 11 patients with TH had acute respiratory *** ALP elevation was not found in any patients with non-inflammatory *** isoenzyme profiles showed a characteristic pattern in all six patients in whom the ALP isoenzyme test was *** Our results suggest an association between respiratory infections and *** consideration of TH in patients with acute respiratory infections may lead to earlier and accurate diagnosis of this condition,thereby avoiding unnecessary medical interventions.

关键词： Alkaline phosphatase Respiratory infection Transient hyperphosphatasemia Isoenzyme