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应用于虹膜缺失和白化病患者的黑色隔膜无虹膜型人工晶体

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世界核心医学期刊文摘（眼科学分册） 2005年第10期1卷 49-50页

作者： Wong V.W.Y. Lam P.T.H. Lai T.Y.Y. Lam D.s.C. 潘佳鸿 Department of Ophtha lmology and Visual sciences Hong Kong Eye Hospital The Chinese University of H ong Kong 147KArgyle Street HongKong HongKong

Background: Our aim was to assess the safety and efficacy of primary and secon dary implantation of a black diaphragm aniridia intraocular lens (IOL) in patien ts that lacked a complete iris diaphragm. Methods: This was a retrospective non -comparative study of six eyes in five patients with iris defects. The causes o f such defects included congenital aniridia, traumatic aniridia, and oculocutane ous albinism. Three eyes underwent primary implantations of a black diaphragm IO L, and three eyes were given secondary implantations. The visual acuity, subject ive severity of glare, postoperative anatomical outcome and any intraoperative o r postoperative complications were reviewed. Results: The mean follow-up period was 20.6 months (range 3-29 months. All patients showed stable or improvement in best-corrected visual acuity postoperatively. Glare and photophobia had impr oved subjectively in all patients after implantation of the black diaphragm IOL. Intraoperative complication included one case of hyphaema and iris damage durin g insertion of the IOL. Postoperative complications included intraocular inflamm ation with choroidal detachment, secondary glaucoma, and persistent epithelial d efect after surgery. None of the patients developed decentration of IOL after su rgery. Conclusion: The black diaphragm aniridia IOL is useful in the management of the condition in patients with iris deficiency including oculocutaneous albin ism. Intraoperative and postoperative complications are not uncommon, and patients should be monitored carefully in the perioperative period.

关键词：虹膜型人工晶体虹膜缺失虹膜缺损外伤性无虹膜脉络膜脱离上皮缺损眩光眼内炎矫正视力前房出血

Prevalence of suicidal Risk in the General Population in Parakou (Benin) in 2022

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Open Journal of Psychiatry 2023年第4期13卷 304-323页

作者： Ataigba Ireti Nethania Elie Aza-Gnandji Guy Gérard sossa Megni Gbenondjihou Elie Adeossi Kintossi Feldia Bernice Bernice Zingbe Cadnella Marieange Moussa Djibrilla Awohouedji Dèdonougbo Mêmêgnon Tokpanoude Coovi Nonwanou Ignace Djossou sègnon Eurydice Elvire Djidonou Anselme Tognon Tchegnonsi Francis Gandaho Proper Ezin Houngbe Josiane Faculté de Médecine & Institut de Formation en soins Infirmiers et Obstétricaux Université de Parakou Parakou Bénin Centre Hospitalier Universitaire Départemental du Borgou Alibori de Parakou: service de psychiatrie Parakou Bénin Organisation Non Gouvernementale de soutien de Réhabilitation d’Insertion et de Réinsertion (SouRIR ONG) Parakou Bénin Faculté des sciences de la santé Université d’Abomey-Calavi Cotonou Bénin Centre National Hospitalier Universitaire-Hubert Koutoucou Maga de Cotonou: service de Psychiatrie Cotonou Bénin Centre National Hospitalier Universitaire Psychiatrique de Cotonou: Unité de psychiatrie de l’enfant et de l’adolescent Cotonou Bénin Faculté des sciences de la santé Université André Salifou de Zinder Zinder Niger service de Psychiatrie H&#244pital National de Zinder Zinder Niger Faculté des sciences de la santé U nité de Santé Publique Cotonou Bénin

Introduction: Every year worldwide, the WHO estimates that nearly one million people take their own lives, the equivalent of one suicide occurring every 40 seconds, despite the fact that this harm is preventable. Objective: The aim of this study is to investigate the risk of suicide in the general population in the commune of Parakou in 2022. Methods: Descriptive cross-sectional study conducted from December 2021 to December 2022. sampling was probabilistic, using the WHO cluster sampling technique. Results: A total of 582 subjects were surveyed, of whom 99 (17.01%) were at risk of suicide (low (7.6%), moderate (5.7%) and high (3.8%)). Evaluation of suicidal behaviors revealed suicidal ideation (15.12%), suicidal planning (4.46%), suicide attempts (3.78%) and suicidal equivalents (6.90%). After multivariate analysis, the following were statically associated with suicidal risk: wet nurse status of less than one month (p = 0.003), family history of suicide attempt (p = 0.004), lack of affection from parents or guardians (p = 0.044), poor relationship with partner (p = 0.033) and depression (p = 0.001). Conclusion: Approximately one person in five is at risk of suicide at the end of this study. There is every interest to implement effective preventive measures at national level.

关键词： Risk suicide Benin-2022

酯化的肉毒碱胆汁内异常聚集:一种预后较差的小儿急性肝衰竭的特征

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世界核心医学期刊文摘（胃肠病学分册） 2005年第8期1卷 47-47页

作者： shneider B.L Rinaldo P Emre s 王铮 Mount sinai school of Medicine Box 1656 One GustaveL. Levy Place New York NY 10029 United States

The etiology of acute liver failure in children is unknown in a large number o f cases. Defects in fatty acid oxidation have been shown to lead to severe liver injury. This retrospective analysis examined the bile acylcarnitine profiles of 27 children with acute liver failure who underwent liver transplantation or die *** were compared with 758 postmortem samples from individuals without acu te liver failure. Cumulative amounts of free carnitine, medium-or long-chain s pecies in excess of the 95th percentile of the control group were considered abn *** samples had normal profiles. Three had markedly elevated concentr ations of free carnitine, whereas ten showed elevations in medium-or long-chai n species. The relative risk of death was 2.86 (95%confidence interval, 1.08-7 .54, P = .01)in the 10 children with elevated concentrations of medium-or long -chain species compared with those with normal ***, medium-and lo ng-chain acylcarnitines were increased in those patients who died compared with survivors, (dead vs. alive; medium-chain, 187±74 vs. 32±12 μmol/L, P=.008;l ong-chain, 146±74 vs.15±8 μmol/L, mean±standard error of the mean, P=.018). These studies describe biliary free and esterified carnitine profiles in childr en with acute liver failure. In conclusion, the findings raise the hypothesis th at abnormalities in fatty acid oxidation may predispose to a worse outcome in ac ute liver failure.

关键词：急性肝衰竭肉毒碱脂肪酸氧化肝损伤样本含量尸体标本肝移植中长链病例研究生存者

老年性黄斑变性患者单核细胞活化:脉络膜新生血管的危险生物标志物

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世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 23-23页

作者： Cousins s.W. Espinosa-Heidmann D.G. Csaky K.G. 侯进 William L. McKnight Vis. Res. Center Bascom'Palmer Eye Institute 1638 NW 10th Ave Miami FL 33136 United States Dr.

Objective: To evaluate the activation state of macrophage function in patients with age-related macular degeneration (AMD) by quantifying the production of t he proinflammatory and angiogenic factor tumor necrosis factor α(TNF-α) and b y correlating its expression with dry and wet AMD. Methods: Circulating monocyte s were obtained from the blood of patients with AMD or age-matched control subj ects by gradient centrifugation. The monocytes were then analyzed for either TNF -αrelease from cultured macrophages in response to retinal pigment epithelium -derived blebs and cytokines or TNF-αmessenger RNA content by reverse transcr iptasepolymerase chain reaction. Results: In human monocytes obtained from contr ols and AMD patients, TNF-αwas expressed by freshly isolated monocytes and pro duced by macrophages in culture after stimulation with retinal pigment epitheliu m-derived blebs. However, wide variability in TNF-αexpression was observed am ong different patients. Patients with monocytes that expressed the greatest amou nt of TNF-αdemonstrated higher prevalence of choroidal neovascularization. Con clusions: Both controls and AMD patients vary in the activation state (defined a s TNF-αexpression) of circulating monocytes. Partially active monocytes, defin ed as high TNF-αexpression, may be a biomarker to identify patients at risk fo r formation of choroidal neovascularization. Clinical of Relevance: Early diagno stic testing may prove useful to detect those patients who will progress to the more severe complications of the disease.

关键词：老年性黄斑变性脉络膜新生血管生物标志物视网膜色素上皮巨噬细胞分析分离外周循环梯度离心法诊断性检查活化状态

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HAV、HBV与HCV感染相互关系的研究

实用医技杂志 2004年第9B期11卷 1933-1934页

作者：文汉成安社刚易建华陕西省友谊医院陕西西安710068 潼关县人民医院陕西潼关714300

目的 :探讨甲、乙、丙三种病毒性肝炎感染的相互关系。方法 :应用RIA法对 2 72 9例患者的血清标本同时测定了甲、乙、丙三种肝炎病毒感染的血清学指标。结果 :甲、乙、丙三种类型的肝炎病毒感染与其他血清标志物各组间差异无显著性 (P >... 详细信息

目的 :探讨甲、乙、丙三种病毒性肝炎感染的相互关系。方法 :应用RIA法对 2 72 9例患者的血清标本同时测定了甲、乙、丙三种肝炎病毒感染的血清学指标。结果 :甲、乙、丙三种类型的肝炎病毒感染与其他血清标志物各组间差异无显著性 (P >0 .0 5 )。结论 :甲、乙、丙三种病毒性肝炎感染相互独立 ,机体无交叉免疫功能。

关键词： HAV感染 HBV感染 HCV感染甲肝乙肝丙肝相互作用

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山东苍山羊山金矿床地质特征

山东国土资源 2003年第4期19卷 26-29页

作者：杜显彪马昭建戚树林刘铭安仰生张旭山东省第二地质矿产勘查院山东兖州272100 山东省第一地质矿产勘查院山东济南250014

山东省苍山县羊山金矿床位于沂沭断裂带以西,燕甘断裂南段东侧,赋存于九龙群三山子组地层中,矿体受NE向次级构造控制,呈脉状产出,为与燕山期岩浆活动密切相关的中低温热液(充填)型金矿床。

关键词：山东金矿床矿床地质三山子组 NE向构造中低沮热液