检索结果-南通市图书馆

A novel supramolecular assembly based on nor-seco-cucurbit[10]uril for spermine sensing and artificial light-harvesting

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2025年第1期36卷 262-266页

作者： Ran Cen Yan-Yan Tang li-Xia Chen Zhu Tao Xin Xiao National Key Laboratory of Green Pesticide State Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationKey Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou ProvinceGuizhou UniversityGuiyang 550025China

A supramolecular assembly composed of perylene diimide derivative(PDI-nm)and nor-secocucurbit[10]uril(ns-q[10])was *** excellent host-guest interaction between PDI-nm and nsq[10]prevented the aggregation-caused quenching(ACq)effect of PDI-nm,resulting in a luminescent *** addition of spermine to the PDI-nm/ns-q[10]assembly restored the ACq of PDI-nm due to the competitive binding of spermine to ns-q[10],which released *** assembly based on this principle showed ultra-high sensitivity for the detection of spermine with a detection limit as low as7.84×10^(-7)mol/L in aqueous solution and 3.69×10^(-7)mol/L in plasma ***,an artificial light-harvesting system based on this assembly was proposed,benefiting from its good luminescent *** red(Ni R)functioned as an acceptor loaded into assembly,and a highly efficient energy transfer process occurred from PDI-nm/ns-q[10]to Ni R,with an efficiency up to 87%.

关键词： Nor-seco-cucurbituril Perylene diimide derivative spermine light-harvesting

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang li Xiaomei Tang Jinyu Zeng Yige song Chao Xu Kai Zhao Guoqiang liu Youming Lu Xinyan li Kai shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

Influence of Fe Addition on Products of self-Propagating High-Temperature synthesis Reaction in 3Ti-si-2C system

在线全文

学校读者我要写书评

暂无评论

稀有金属材料与工程 2009年第A03期38卷 113-118页

作者： Guan q L Wang H Y li s L si W P Jiang q C Key Laboratory of Automobile Materials of Ministry of Education Jilin University Changchun 130025 China

Influence of Fe addition on products of self-propagating high-temperature synthesis (sHs) reaction in 3Ti-si-2C system was investigated in the present study. Without Fe addition, Ti5si3 and TiC are the dominant phases along with a small amount of Ti3siC2 phase and unreacted C left in the final products. As Fe content ranges from 10% to 30%, the products consist of TiC, Ti5si3, Fe2Ti and unreacted C, but no trace of Ti3siC2 phase is detected. Furthermore, the amounts of both Fe2Ti and C phases increase with Fe content increasing. Addition of Fe has a great effect on the reaction route and significantly restrains the formation of Ti3siC2 during the combustion synthesis process, and therefore, the sHs is not an effective fabrication technique to synthesize the ternary Ti3siC2 ceramic in either 3Ti-si-2C or Fe-3Ti-si-2C system. Besides, without Fe addition, Ti5si3 presents as the coarse irregular appearance with an obviously sintered morphology. In contrast, the shape of Ti5si3 exhibits more and more spherical (cobblestone-like) and the surface becomes increasingly smooth, because the amount of liquids formed during the sHs reaction increases with the increase of Fe content. On the other hand, with Fe content increasing from 0 to 30 wt.%, the particulate size of TiC decreases from more than 5 μm to 1 μm or less, mainly due to the fact that the combustion temperature decreases with the increase of Fe content in the preforms.

关键词：复合材料铁含量燃烧过程物理性能

On the Multi-q Characteristics of Magnetic Ground states of Honeycomb Cobalt Oxides

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2025年第02期 76-86页

作者： Yuchen Gu Xianghong Jin Yuan li International Center for quantum Materials School of PhysicsPeking University Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of Sciences

The Kitaev honeycomb model has received significant attention due to its exactly solvable quantum spin liquid ground states and fractionalized excitations. Layered cobalt oxides have been considered as a promising pla...

关键词：

THERMAL sTREssEs RELAXATION DEsIGN OF Ni/NiFe_(2)O_(4) sYsTEM FUNCTIONALLY GRADED CERMET INERT ANODE

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Metallurgica sinica(English Letters) 2005年第5期18卷 635-641页

作者： J. li q.s. Zhang Y.q. Lai s.L. Ye Y.X. liu school of Metallurgy science and Engineering Central South University Changsha 410083 China

The thermal stresses relaxation of Ni/NiFe2O4 system functionally graded cermet inert anode for aluminum electrolysis was optimally designed. The transient thermal stresses of the inert anode under complex boundary condition during high-temp （955℃） electrolysis were calculated using the finite-element software ANsYs, the influence of different parameters on the distribution of the thermal stresses were analyzed. The results showed that, during the process of thermal shock, the thermal hoop tensile stress on the surface of the anode is very large, which is possibly the major cause of anode crack; when the radius of the anode is between 0.05-0.15m, a range that can be realized by recent manufacturing technology, the optimum composition distribution exponent p is 0.25; The hoop tensile stresses reduce with the decrease of anode scale and also decrease with the decrease of the convection coefficient between the electrolyte and the anode.

关键词： functionally graded material (FGM) transient thermal stresses ANsYs inert anode aluminum electrolysis

Twinnability Predication for fcc Metals

在线全文

学校读者我要写书评

暂无评论

Journal of Materials science & Technology 2011年第2期27卷 97-100页

作者： B.q.li M.L.sui s.X.Mao shenyang National Laboratory for Materials science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Institute of Microstructure and Properties of Advanced Materials Beijing University of TechnologyBeijing 100124China Department of Mechanical Engineering and Materials science University of PittsburghPittsburghPennsylvania 15261USA

Inherent twinnability of face-centered-cubic（fcc） metals was analyzed based on the direct competition between twinning partial dislocation nucleation and trailing partial dislocation nucleation,with which the twinnability of fcc metals can be simply expressed as function of the stacking-fault energy,the unstable stacking-fault energy,and the unstable twinningfault energy of fcc *** predicted twinnability ranking matched well with former experimental results and provided a physical insight to understand twinnability from crystallographic orientation and fault energy parameters.

关键词： Deformation twinning fcc metals Twinnability

A Dynamic Knowledge Base Updating Mechanism-Based Retrieval-Augmented Generation Framework for Intelligent question-and-Answer systems

在线全文

学校读者我要写书评

暂无评论

Journal of Computer and Communications 2025年第1期13卷 41-58页

作者： Yu li Technical Research Center China Datang Digital Technology Co. Ltd. Baoding China school of Mechanical Engineering Xian Jiaotong University Xian China

In the context of power generation companies, vast amounts of specialized data and expert knowledge have been accumulated. However, challenges such as data silos and fragmented knowledge hinder the effective utilization of this information. This study proposes a novel framework for intelligent question-and-Answer (q&A) systems based on Retrieval-Augmented Generation (RAG) to address these issues. The system efficiently acquires domain-specific knowledge by leveraging external databases, including Relational Databases (RDBs) and graph databases, without additional fine-tuning for Large Language Models (LLMs). Crucially, the framework integrates a Dynamic Knowledge Base Updating Mechanism (DKBUM) and a Weighted Context-Aware similarity (WCAs) method to enhance retrieval accuracy and mitigate inherent limitations of LLMs, such as hallucinations and lack of specialization. Additionally, the proposed DKBUM dynamically adjusts knowledge weights within the database, ensuring that the most recent and relevant information is utilized, while WCAs refines the alignment between queries and knowledge items by enhanced context understanding. Experimental validation demonstrates that the system can generate timely, accurate, and context-sensitive responses, making it a robust solution for managing complex business logic in specialized industries.

关键词： Retrieval-Augmented Generation question-and-Answer Large Language Models Dynamic Knowledge Base Updating Mechanism Weighted Context-Aware similarity

Astragali Radix-Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2025年第1期23卷 54-63页

作者： Pingping lin Hong Chen Zekun Cui Boyang Yu Junping Kou Fang li Jiangsu Key Laboratory of TCM Evaluation and Translational Research Research Center for Traceability and Standardization of TCMs School of Traditional Chinese PharmacyChina Pharmaceutical University

Astragali Radix(AR) and Notoginseng Radix et Rhizoma(NR) are frequently employed in cardiovascular disease treatment. However, the efficacy of the AR-NR medicine pair(AN) in improving cardiac remodeling and its underlying mechanism remains unclear. This study aimed to evaluate AN's cardioprotective effect and potential mechanism on cardiac remodeling using transverse aortic constriction(TAC) in mice and angiotensin II(Ang II)-induced neonatal rat cardiomyocytes(NRCMs) and fibroblasts in vitro. High-performance liquid chromatography-quadrupole-time of flight tandem mass spectrometry(HPLC-q-TOF-Ms/Ms) characterized 23 main components of AN. AN significantly improved cardiac function in the TAC-induced mice. Furthermore, AN considerably reduced the serum levels of N-terminal pro-B-type natriuretic peptide(NT-pro BNP), cardiac troponin T(CTn-T), and interleukin-6(IL-6) and mitigated inflammatory cell infiltration. Post-AN treatment, TAC-induced heart size approached normal. AN decreased cardiomyocyte cross-sectional area and attenuated the upregulation of cardiac hypertrophy marker genes(ANP, BNP, and MYH7) in vivo and in ***, AN alleviated collagen deposition in TAC-induced mice. AN also reduced the expression of fibrosis-related indicators(COL1A1 and COL3A1) and inhibited the activation of the transforming growth factor-β1(TGF-β1)/mothers against decapentaplegic homolog 3(smad3) pathway. Thus, AN improved TAC-induced cardiac remodeling. Moreover, AN downregulated p-dynamin-related protein(Drp1)(ser616) expression and upregulated mitogen 2(MFN-2) and optic atrophy 1(OPA1) expression in vivo and in vitro, thereby restoring mitochondrial fusion and fission balance. In conclusion, AN improves cardiac remodeling by regulating mitochondrial dynamic balance, providing experimental data for the rational application of Chinese medicine prescriptions with AN as the main component in clinical practice.

关键词： Astragali Radix−Notoginseng Radix et Rhizoma medicine pair Cardiac fibrosis Cardiac hypertrophy Mitochondrial dynamics Transforming growth factor-β1/smad3 pathway

ON THE BURN REsIsTANCE OF Ti-35V-15Cr-0.05C TITANIUM ALLOY

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Metallurgica sinica(English Letters) 1998年第3期11卷 202-206页

作者： G.P.li D.li Y.Y.liu q.J.Wang s.X.Guan q.C.li Inst of Metal Research The Chinese Acad of Sciences Shenyang China

The Ti-35V-15Cr-0.05C (wt% is a new nonburning titanium alloy. The test for alloy combustibility was carried out by using CO2 laser. A 430 watt and 6mm diameter laser spot impinges directly on the sample within normal atmospheric pressure and temperature. The results show that the ignition time of the nonburning titanium alloy is the longest in the eight examined titanium alloys, and is 3.5 times that of TC4 alloy. The ignition tempeerature of the nonburning alloy is 2991° C, and is higher than that of TC4 alloy by 1976°C. On the condition of high tempeerature and rich oxygen,the surface of alloy forms a melting layer which plays roles of oxygen insulation, heat insulation and burning products insulation. This is the mechanism of combustion resistance.

关键词： Ti-35V-15Cr-0.05C (wt%) nonburning titanium alloy combustion resistance