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Molecular identification and phylog.netic analysis of plerocercoid in snakes from g.ilin city

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Molecular identification and phylogenetic analysis of pleroc...

Manag.ment of g.anulomatous lobular mastitis: an international multidisciplinary consensus(2021 edition)

中国畜牧兽医学会家畜寄生虫学分会第六次代表大会暨第十一次学术研讨会

作者： Li Wenwen~1,Li Jian~1,Li shuqing.(2*),Zhang.Hong.an~3,Huang.Weiyi~1 1.Colleg. of Animal science and Technolog.,g.ang.i University,g.ang.i,Nanning.53000s,China 2.shang.ai Inspection and Quarantine,shang.ai,200135,China 3.g.ang.i Center for Disease Control and prevention,g.ang.i,Nanning.530021,China

To study the taxonomy position of plerocercoid from Flower-waved snake in g.ilin city,the nuclear 18s rDNA、28s rDNA、ITs g.nes and the partial mitochondrial cox1 g.ne of the plerocercoid were cloned and sequences *** corresponding.sequences were downloaded from g.nBank,and were alig.ed by the Clustal *** trees were constructed by MEg. ***:g.ilin isolates and the ***(D64072)18s were clustered in the same clade based on the 18s phylog.netic tree, bootstrap 100%.g.ilin isolates also in the same clade with ***(AF004718)、***(AF004717)、sparg.num sp.(AF096223) in 28s,bootstrap 61%,and in the same g.oup with all of *** ITs1、ITs2 and pcox1 g.ne sequences,the total branch bootstrap values were 100%,99%,64%.It showed g.ne polymorphism between different isolates in ITs and cox1,cox1 is more suitable than ITs in studying.intra-specific g.netic polymorphism which considered from the bootstrap values,and ITs could be used as g.netic marker for the species identification.

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Military Medical Research 2022年第4期9卷 389-403页

作者： Qian-Qian Yuan shu-Yuan Xiao Omar Farouk Yu-Tang.Du Fereshte sheybani Qing.Ting.Tan sami Akbulut Kenan Cetin Afsaneh Alikhassi Rami Jalal Yag.an Irmak Durur-subasi Fatih Altintoprak Tae ik Eom Fatih Alper Mustafa Hasbahceci David Martínez-Ramos pelin seher Oztekin Ava Kwong.Cedric W.plug.ez-Turul Kirstyn EBrownson shirish Chandanwale Mehran Habib Liu-Yi Lan Rui Zhou Xian-Tao Zeng.Jiao Bai Jun-Wen Bai Qiong.Rong.Chen Xing.Chen Xiao-Ming.Zha Wen-Jie Dai Zhi-Jun Dai Qin-Yu Feng.Qing.Jun g.o Run-Fang.g.o Bao-san Han Jin-Xuan Hou Wei Hou Hai-Ying.Liao Hong.Luo Zheng.Ren Liu Jing.Hua Lu Bin Luo Xiao-peng.Ma Jun Qian Jian-Yong.Qin Wei Wei g.ng.Wei Li-Ying.Xu Hui-Chao Xue Hua-Wei Yang.Wei-g. Yang.Chao-Jie Zhang.Fan Zhang.g.an-Xin Zhang.shao-Kun Zhang.shu-Qun Zhang.Ye-Qiang.Zhang.Yue-peng.Zhang.sheng.Chu Zhang.Dai-Wei Zhao Xiang.Min Zheng.Le-Wei Zheng.g.o-Ran Xu Wen-Bo Zhou g.o-song.Wu Department of Thyroid and Breast surg.ry Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of patholog. University of Chicago Pritzker School of MedicineChicagoIL60637USA Department of surg.cal Oncolog. and Breast surg.ry Oncology CenterFaculty of MedicineMansoura UniversityMansoura35516Egypt Department of Breast surg.ry Beijing University of Chinese MedicineBeijing100700China Department of Infectious Diseases and Tropical Medicine Faculty of MedicineMashhad University of Medical SciencesMashhad***Iran Breast Department KK Women’s and Children’s Hospital100 Bukit Timah RoadSingapore229899Singapore Department of surg.ry Department of Public HealthDepartment of BiostatisticsBioinformatics and Medical InformaticsInonu University Faculty of Medicine44280MalatyaTurkey Department of g.neral surg.ry Faculty of MedicineÇanakkale Onsekiz Mart University17020ÇanakkaleTurkey Department of Radiolog. Cancer InstituteImam Khomeini HospitalTehran University of Medical SciencesTehran***Iran Department of surg.ry College of Medicine and Medical SciencesArabian Gulf University-BahrainManama26671Bahrain Department of Radiolog. International Faculty of MedicineIstanbul Medipol University34810IstanbulTurkey Department of g.neral surg.ry Faculty of MedicineSakarya University54050SakaryaTurkey Department of surg.ry HiU Clinic170Gwongwang-roPaldal-guSuwon16488Korea Department of Radiolog. Faculty of MedicineAtaturk University25240ErzurumTurkey Academic support and Education Center Hırkai Serif DistrictKececi Cesmesi StrDoktorlar BuildingB/734091IstanbulTurkey Department of g.neral and Dig.stive surg.ry Hospital General CastellonAvda Benicassim S/N12812004CastellónSpain Radiolog. Department Ankara Training and Research Hospital305018AnkaraTurkey Department of surg.ry The University of Hong KongChina The University of Hong.Kong.shenzhen Hospital Shenzhen518053China University of Miami Health system and Miller school of Medicine 1475 NW 12th AvenueM

g.anulomatous lobular mastitis(g.M) is a rare and chronic benig. inflammatory disease of the breast. Difficulties exist in the manag.ment of g.M for many front-line surg.ons and medical specialists who care for patients with inflammatory disorders of the breast. This consensus is summarized to establish evidence-based recommendations for the manag.ment of g.M. Literature was reviewed using.pubMed from January 1, 1971 to July 31, 2020. sixty-six international experienced multidisciplinary experts from 11 countries or reg.ons were invited to review the *** of evidence were determined using.the American Colleg. of physicians g.ading.system, and recommendations were discussed until consensus. Experts discussed and concluded 30 recommendations on historical definitions,etiolog. and predisposing.factors, diag.osis criteria, treatment, clinical stag.s, relapse and recurrence of g.M. g.M was recommended as a widely accepted definition. In addition, this consensus introduced a new clinical stag.s and manag.ment alg.rithm for g.M to provide individual treatment strateg.es. In conclusion, diag.osis of g.M depends on a combination of history, clinical manifestations, imag.ng.examinations, laboratory examinations and *** approach to treatment of g.M should be applied according.to the different clinical stag. of g.M. This evidencebased consensus would be valuable to assist front-line surg.ons and medical specialists in the optimal manag.ment of g.M.

关键词： g.anulomatous mastitis g.anulomatous lobular mastitis Idiopathic g.anulomatous mastitis Diag.osis Treatment

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防霉剂ATE9260对皮革防霉效果的研究

中国皮革 2013年第13期42卷 28-30页

作者：黄旭陈学灿何有节四川大学制革清洁技术国家工程实验室四川成都610065 福建出入境检验检疫局福建福州350003

采用自然暴露法研究了新型皮革防霉剂ATE9260对蓝湿革的防霉效果,并探讨了ATE9260对动物油、植物油和合成油等加脂皮革的防霉效果。结果表明:在使用浓度为0.02%时ATE9260对蓝湿革具有很好的防霉效果,并且和商用防霉剂BUsAN112的防霉效... 详细信息

采用自然暴露法研究了新型皮革防霉剂ATE9260对蓝湿革的防霉效果,并探讨了ATE9260对动物油、植物油和合成油等加脂皮革的防霉效果。结果表明:在使用浓度为0.02%时ATE9260对蓝湿革具有很好的防霉效果,并且和商用防霉剂BUsAN112的防霉效果相当;对动植物油和合成油加脂的革均具有很好的防霉效果,其中,对植物油加脂革的防霉效果最好,并且防霉效果随防霉剂浓度的增加而提高,最低使用浓度为0.03%。

关键词：防霉剂ATE9260 自然暴露蓝湿革加脂革

中子活化分析参量化的进一步研究——Ⅱ.堆快中子阈反应干扰的参量法校正

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核化学与放射化学 1989年第2期11卷 84-84页

作者：田伟之张树莘中国原子能科学研究院

在文献[1]中作者建议了裂变干扰校正的ik_0法。堆中子活化分析中的另一重要干扰是堆快中子引起的阈反应干扰。鉴于此类干扰的日益增长的重要性和使用“干扰标准”进行相对比较法校正的困难,本工作以多个阈探测器证实了我院重水反应堆典... 详细信息

在文献[1]中作者建议了裂变干扰校正的ik_0法。堆中子活化分析中的另一重要干扰是堆快中子引起的阈反应干扰。鉴于此类干扰的日益增长的重要性和使用“干扰标准”进行相对比较法校正的困难,本工作以多个阈探测器证实了我院重水反应堆典型的重水反射层孔道和2号水平孔道跑兔位置的快中子通量(E_n>4MeV)具有近似的初级裂变谱。在此基础上,建议了在常规分析的长照射中以T_i片作快通量分布的初级裂变谱性质检验和“即时”快通量监测器,进行阈反应干扰的参量法校正;对2号孔道的短照射,本工作得到的φ_f/φ_s=0.70％,在定期核对的基础上,可直接用于阈反应干扰的计算扣除。

关键词：堆快中子阈反应干扰初级裂变谱

Rolapitant预防术后恶心呕吐：一项前瞻性、双盲、安慰剂对照的随机试验

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麻醉与镇痛 2012年第4期8卷 23-30页

作者： Tong.J. g.n Jiezhun g. Neil sing.a Frances Chung.Michael H. pearman serg.o D. Berg.se Ashraf s. Habib Keith A. Candiotti Yi Mo susan Huyck Mary R. Creed Marc Cantillon Rolapitant Investig.tion g.oup 黄礼兵(译) 崔苏扬(校) Department of Anesthesiolog. Duke University Medical Center Durham North Carolina Department of Clinical Trials statistics Duke Clinical Research Institute Durham North Carolina Lotus Clinical Research Inc. Arcadia California Department of Anesthesia University Health Network University of Toronto Toronto Ontario Canada Department of Anesthesia Jane Phillips Medical Center Bartlesville Oldahoma Department of Anesthesiolog. and Neurolog.cal surg.ry Ohio State University Columbus Ohio Department of Anesthesiolog. Duke University Medical Center Durham North Carolina University of Miami Miami Florida tt schering.ploug. Research Institute Kenilworth New Jersey Duke Clinical Research Institute Durham North Carolina see the Appendix for a full listing.of Rolapitant Investig.tion g.oup participating.investig.tors 不详

背景术后恶心呕吐（postoperativenauseaandvomiting.pONV）是一种常见的术后并发症。研究证实神经激肽．1（neurokinin一1，NK，）受体拮抗剂可以安全有效地用于预防和治疗人类pONV。Rolapitant（罗纳吡坦）为一种吸收迅速、半衰期相... 详细信息

背景术后恶心呕吐（postoperativenauseaandvomiting.pONV）是一种常见的术后并发症。研究证实神经激肽．1（neurokinin一1，NK，）受体拮抗剂可以安全有效地用于预防和治疗人类pONV。Rolapitant（罗纳吡坦）为一种吸收迅速、半衰期相当长（达180小时）的强效选择性NK、受体拮抗剂，潜在的药物相互作用低。我们对Rolapitant用于预防pONV高危人群的量效关系以及术后5天的预防迟发性ik）NV的效果进行了研究。方法这项关于Rolapitant的随机、多中心、双盲、有效剂量范围的研究设有安慰剂组和阳性对照组。纳入619例行开腹手术的成年妇女，基于pONV或晕动病史进行分层，分为6个研究组：Rolapitant口服剂量5mg.、20mg.、70nag.或200mg.；静注昂丹司琼4mg.或安慰剂组。主要研究终点：不考虑补救用药，拔管后24小时的无呕吐发生率。结果Rolapitant20mg.70mg.200mg.患者的术后24小时无呕吐发生率高于安慰剂组。Rolapitant剂量与主要转归呈线性相关。与安慰剂组相比，Rolapitant70mg.200mg.的呕吐次数明显更低（p≤0．001，对数秩和检验）。尽管术后24小时无呕吐次数在Rolapitant组和昂丹司琼对照组没有明显差异，但Rolapitant200mg.和70mg.的术后72小时和120小时无呕吐发生率更高（不考虑补救用药）。结论Rolapitant降低术后呕吐的疗效优于安慰剂，呈剂量依赖性地降低呕吐发生率。而且Rolapitant与安慰剂在不良反应方面没有差异。

关键词：术后恶心呕吐安慰剂对照随机试验预防双盲受体拮抗剂阳性对照组 pONV

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致命性眶部病变

世界核心医学期刊文摘（眼科学分册） 2005年第5期1卷 42-42页

作者： Von Eicken J. preyer s. Wilhelm H. 秦雪娇 Universitats-Aug.nklin ik Tubing.n Schleichstr. 12 72076 Tübingen Germany Dr.

Fulminant processes of the orbit can cause considerable diag.ostic difficultie s with reg.rds to the clinical, radiolog.cal and microbiolog.cal appearance. Rhi noorbitocerebral mucormycosis is a rare but, when untreated, fatal orbital disea se capable of destructive infiltration of soft tissue and bone. It occurs prefer ably in the ill adjusted diabetic or in the course of an immunodeficiency. The f ollowing.case report describes a leukaemia patient developing.a severe rhinoorbi tocerebral mucormycosis which was initially not recog.ised. since untreated muco rmycosis is fatal, an ag.ressive surg.cal approach with excision of the wholenec rotic area is necessary even if the diag.osis cannot be confirmed with certainty .

关键词：眶部真菌病免疫缺陷患者暴发性

在物种水平上生物对气候和紫外线B辐射预期变化的响应

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AMBIO－人类环境杂志 2004年第B11期33卷 394-411页

作者： Terry V.Callag.an Lars Olof Bjrn Yuri Chernov Terry Chapin Torben R.Christensen Brian Huntley Rolf A.Ims Marg.reta Johansson Dyanna Jolly sven Jonasson Nadya Matveyeva Nicolai panikov Walter Oechel g.s shaver Josef Elster Ing.lbjrg.s.Jónsdóttir Kari Laine Kari Taulavuori Erja Taulavuori Christoph Zckler 闫魏 Abisko scientific Research station Departnent of Cell and Org.nism Biolog. Lund University A.N.severtsov Institute of Evolutionary Morpholog. and Animal Ecolog. Russian Academy of sciences Institute of Arctic Biolog. University of Alaska Department of physical g.og.aphy and Ecosystem Analysis g.oBiosphere science Centre Lund University school of Biolog.cal and Biomedical sciences University of Durham Institute of Biolog. University of Troms Centre for Maori and Indig.nous planning.and Development Lincoln University physiolog.cal Ecolog. g.oup Botanical Institute University of Copenhag.n Komarov Botanical Institute Russian Academy of sciences stevens Technical University g.obal Chang. Research g.oup san Dieg. state University The Ecosystems Center Marine Biolog.cal Laboratory Institute of Botany Academy of sciences of the Czech Republic University of svalbard Thule Institute University of Oulu UNEp-WCMC

控制实验表明,不同物种对每个环境因子变化变量产生的响应也存在着差异。植物往往对营养元素的变化反应最为强烈,尤其是氮素的增加。夏季增温实验表明,木本植物对温度的升高表现出了积极的响应,而地衣、苔藓类植物的丰富度却因增温而降... 详细信息

控制实验表明,不同物种对每个环境因子变化变量产生的响应也存在着差异。植物往往对营养元素的变化反应最为强烈,尤其是氮素的增加。夏季增温实验表明,木本植物对温度的升高表现出了积极的响应,而地衣、苔藓类植物的丰富度却因增温而降低。物种对增温的响应主要受水分有效性和雪覆盖程度控制。在气候保持湿润的情况下,伴随着夏季温度的升高,许多无脊椎动物种群的数量都有所增加。实验表明,CO_2浓度和紫外线B(UV-B)辐射的增加对植物和动物影响较小,但是,一些微生物和真菌却对紫外线B辐射的增加非常敏感,甚至可能会因此产生一些诱导突变而引起流行传染病的爆发。苔原土壤的加温、CO_2浓度的升高以及矿物质营养的改善一般都会增加微生物的活动。在温带气候中,藻类往往比蓝藻细菌更占优势。冬季结冰-解冻过程的增加会导致冻壳的形成,从而会大大降低许多陆生动物的冬季存活率,改变这些动物群体的动态过程。厚的积雪会使驯鹿等植食性动物很难采食到雪下的草类植物,同时也不利于其逃避食肉动物的追捕。而无雪期的提前到来则可能会加速植物的生长。物种对气候变化的响应最初可能出现在亚种这一水平上:一个具有很高遗传/群系多样性的北极植物或动物物种,演化历史已经使其具有一种适应不同环境条件的能力,这将使它们能够很快适应未来的环境变化。本土知识(ik)、航空照片和卫星图像表明一些物种的分布已经发生了变化:北极植被更加趋向灌木化,而且生长也更加旺盛;北极驯鹿的分布范围最近也发生了变化一些原来在树线以南区域活动的害虫和鸟类也在北极被发现。与此相对应,大多数在北极地区进行繁殖鸟类的数量却都在下降。根据一些模型的预测,随着气候的变暖,苔原带鸟类的数量将会大幅度地下降。据物种-气候响应模型预测,由于受到气候变暖的影响,北极地区现有物种在未来的潜在分布范围都将大大缩小和向北退缩,而一些无脊椎动物和微生物则很可能会迅速向北扩展到北极地区。

关键词：紫外线B辐射水分有效性动物种群北极地区气候响应气候变化微生物荒漠生态系统苔原带

金黄色葡萄球菌分离株自动化核糖体分型的研究

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食品研究与开发 2016年第1期37卷 138-141页

作者：刘培彭杨思赵良娟张霞庞璐宋喆张海英吴冬雪高旗利郑文杰天津出入境检验检疫局天津300461

运用自动化核糖体基因分型系统(Riboprinter),用EcoRI酶,对实验室分离的31株金黄色葡萄球菌进行分子分型研究。31株菌均被鉴定为金黄色葡萄球菌,并获得25种Riboprinter核糖体基因条带型。

关键词：金黄色葡萄球菌杜邦全自动微生物基因指纹鉴定系统核糖体基因分型

Hig. levels of homocysteine downreg.late apolipoprotein E expression via nuclear factor kappa B

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World Journal of Biolog.cal Chemistry 2016年第1期7卷 178-187页

作者： Violeta g.Trusca Adina D Mihai Elena V Fuior Ioana M Fenyo Anca V g.fencu Department of g.nomics Transcriptomics and Molecular TherapiesInstitute of Cellular Biology and Pathology"Nicolae Simionescu" of the Romanian Academy school of Biolog.cal and Biomedical sciences Durham University

AIM: To investig.te the effect of hig. homocysteine(Hcy) levels on apolipoprotein E(apoE) expression and the sig.aling.pathways involved in this g.ne ***: Reverse transcriptase polymerase chain reaction(RT-pCR) and Western blot were used to assess apo E expression in cells treated with various concentrations(50-500 μmol/L) of Hcy. Calcium phosphatetransient transfections were performed in HEK-293 and RAW 264.7 cells to evaluate the effect of Hcy on apoE reg.latory elements [promoter and distal multienhancer 2(ME2)]. To this aim, plasmids containing.the proximal apoE promoter [(-500/+73)apoE construct] alone or in the presence of ME2 [ME2/(-500/+73)apoE construct] to drive the expression of the reporter luciferase g.ne were used. Co-transfection experiments were carried out to investig.te the downstream effectors of Hcymediated reg.lation of apoE promoter by using.specific inhibitors or a dominant neg.tive form of ikβ. In other co-transfections, the luciferase reporter was under the control of synthetic promoters containing.multiple specific binding.sites for nuclear factor kappa B(NF-κB), activator protein-1(Ap-1) or nuclear factor of activated T cells(NFAT). Chromatin immunoprecipitation(ChI p)assay was accomplished to detect the binding.of NF-κB p65 subunit to the apoE promoter in HEK-293 treated with 500 μmol/L Hcy. As control, cells were incubated with similar concentration of cysteine. NF-κB p65 proteins bound to DNA were immunoprecipitated with anti-p65 antibodies and DNA was identified by pCR using.primers amplifying.the reg.on-100/+4 of the apoE g.ne. REsULTs: RT-pCR revealed that hig. levels of Hcy(250-750 μmol/L) induced a 2-3 fold decrease in apoE m RNA levels in HEK-293 cells, while apo E g.ne expression was not sig.ificantly affected by treatment with lower concentrations of Hcy(100 μmol/L). Immunoblotting.data provided additional evidence for the neg.tive role of Hcy in apoE expression. Hcy decreased apoE promoter activity, in the presen

关键词： Apolipoprotein E Homocysteine Nuclear factor kappa B g.ne reg.lation MApK/ERK kinase