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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 81-100页

作者： s.sAURABH R.KiRAN d.siNGH R.VAisH V.s.CHAUHAN school of Mechanical and Materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(iHsdT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the C0finite element method(FEM), and an in-house code is developed in the MATLAB environment to solve it numerically. Various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(Hs), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. Moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

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Photobiomodulation:a novel approach to promote trans-differentiation of adipose-derived stem cells into neuronal-like cells

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Neural Regeneration Research 2025年第2期20卷 598-608页

作者： daniella da silva Madeleen Jansen van Rensburg Anine Crous Heidi Abrahamse Laser Research Centre Faculty of Health SciencesUniversity of JohannesburgDoornfonteinJohannesburgSouth Africa

Photobiomodulation,originally used red and near-infrared lasers,can alter cellular *** has been demonstrated that the visible spectrum at 451-540 nm does not necessarily increase cell proliferation,near-infrared light promotes adipose stem cell proliferation and affects adipose stem cell migration,which is necessary for the cells homing to the site of *** this in vitro study,we explored the potential of adipose-derived stem cells to differentiate into neurons for future translational regenerative treatments in neurodegenerative disorders and brain *** investigated the effects of various biological and chemical inducers on trans-differentiation and evaluated the impact of photobiomodulation using 825 nm near-infrared and 525 nm green laser light at 5 J/*** adipose-derived stem cells can be used in autologous grafting and photobiomodulation has been shown to have biostimulatory *** findings reveal that adipose-derived stem cells can indeed trans-differentiate into neuronal cells when exposed to inducers,with pre-induced cells exhibiting higher rates of proliferation and trans-differentiation compared with the control ***,green laser light stimulation led to notable morphological changes indicative of enhanced trans-differentiation,while near-infrared photobiomodulation notably increased the expression of neuronal *** biochemical analysis and enzyme-linked immunosorbent assays,we observed marked improvements in viability,proliferation,membrane permeability,and mitochondrial membrane potential,as well as increased protein levels of neuron-specific enolase and ciliary neurotrophic ***,our results demonstrate the efficacy of photobiomodulation in enhancing the trans-differentiation ability of adipose-derived stem cells,offering promising prospects for their use in regenerative medicine for neurodegenerative disorders and brain injuries.

关键词： differentiation inducers green photobiomodulation immortalized adipose-derived stem cell near-infrared photobiomodulation neurodegenerative disease neurogenesis photobiomodulation trans-differentiation

dielectric and infrared properties of srTiO_3 single crystal doped by 3d (V,Mn,Fe,Ni) and 4f (Nd,sm,Er) ions

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Chinese Physics B 2014年第2期23卷 369-374页

作者： s.Maletic d.Maletic i.Petronijevic J.dojcilovic d.M.Popovic Faculty of Physics University of Belgrade institute of Physics University of Belgrade

in this study, the effects of doping by 3d （V, Mn, Fe, Ni） and 4f （Nd, sm, Er） ions on dielectric and infrared properties of srTiO3 （sTO） single crystals are investigated. it is well known that doping of the srTiO3 can change the dielectric properties of the sTO from an insulator to an n-type semiconductor, and even to a metallic conductor. dielectric and infrared （iR） properties of the undoped sTO and doped sTO single crystals are analyzed using dielectric spectroscopy （80 kHz-5 MHz）, transmission （200 cm^-1-4000 cm^-1）, and reflection spectroscopy （50 cm^-1-2000 cm^-1）. it is found that doping by the 3d ions reduces the value of dielectric permittivity, but the trend of temperature dependence of the dielectric permittivity remains almost unchanged. On the other hand, dielectric spectroscopy measurements for samples doped by 4f ions show the anomalous behaviors of the dielectric permittivity at temperatures around the temperature of the structural phase transition. There are two fractures of temperature dependences of inverse dielectric permittivity εr^-1 （T）. Transmittance spectroscopy measurements show that there are differences in the shape of the spectrum in the mid-iR region between the undoped sTO and the one doped by 4f ions. The differences in the reflectance spectrum between the sTO：Nd and sTO are analyzed in detail.

关键词： doping dielectric properties phase transitions infrared spectroscopy

Pre screening of Cervical Cancer Through Gradient Boosting Ensemble Learning Method

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intelligent Automation & soft Computing 2023年第3期35卷 2673-2685页

作者： s.priya N.K.karthikeyan d.Palanikkumar Coimbatore institute of Technology CoimbatoreIndia dr.NGP institute of Technology CoimbatoreIndia

in recent years,cervical cancer is one of the most common diseases which occur in any woman regardless of any *** is the deadliest disease since there were no symptoms shown till it is diagnosed to be the last *** women at a certain age,it is better to have a proper screening for cervical *** most underdeveloped nations,it is very difﬁcult to have frequent scanning for cervical *** Mining and machine learning methodologies help widely inﬁnding the important causes for cervical *** proposed work describes a multi-class classiﬁcation approach is implemented for the dataset using support Vector Machine(sVM)and the perception learning *** is known that most classiﬁcation algorithms are designed for solving binary classiﬁcation *** a heuristic approach,the problem is addressed as a multiclass classiﬁcation problem.A Gradient Boosting Machine(GBM)is also used in implementation in order to increase the classiﬁer *** proposed model is evaluated in terms of accuracy,sensitivity and found that this model works well in identifying the risk factors of cervical cancer.

关键词： Cervical cancer sVM GBM ensemble learning

improvement in the corrosion protection and bactericidal properties of AZ91d magnesium alloy coated with a microstructured polypyrrole film

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Journal of Magnesium and Alloys 2018年第1期6卷 15-22页

作者： A.d.Forero López i.L.Lehr L.i.Brugnoni s.B.saidman instituto de ingeniería Electroquímica y Corrosión(iNiEC) Departamento de Ingeniería QuímicaUniversidad Nacional del SurAv.Alem 12538000 Bahía BlancaArgentina instituto de investigaciones Biológicas y Biomédicas del sur(iNBiOsUR) Departamento de BiologíaBioquímica y FarmaciaUniversidad Nacional del SurSan Juan 6708000 Bahía BlancaArgentina

in this work hollow rectangular microtubes of polypyrrole(PPy)films were potentiostatically electrodeposited on magnesium alloy AZ91d in salicylate *** substrate was previously anodized under potentiostatic conditions in a molybdate solution in order to improve the adherence of *** the duplex film was modified by the incorporation of silver *** obtained coatings were characterized by scanning electron microscopy(sEM),X-ray diffraction(XRd)and X-ray photoelectron spectroscopies(XPs)and the antimicrobial activity against the bacteria Escherichia coli was *** corrosion protection properties of the coatings were examined in Ringer solution by monitoring the open circuit potential,polarization techniques and electrochemical spectroscopy(Eis).The duplex coating presents an improved anticorrosive performance with respect to the PPy *** best results concerning corrosion protection and antibacterial activity were obtained for the silver-modified composite coating.

关键词： Polypyrrole duplex coating AZ91d alloy Corrosion resistance Antibacterial properties

Reframing Palliative Care:An East-West integrative Palliative Care Model

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Chinese Journal of integrative Medicine 2021年第10期27卷 723-728页

作者： s.Anjani d.Mattai ka-Kit P.Hui department of Medicine David Geffen School of MedicineUniversity of California Los AngelesCaliforniaUSA Center for East-West Medicine Department of MedicineDavid Geffen School of MedicineUniversity of California Los AngelesCaliforniaUSA

Convergence of principles of palliative care and integrative medicine has led to the introduction of the new practice of integrative palliative care in which integrative therapies(including mind-body modalities,traditional Chinese medicine,Ayurveda,and dietary supplements)are used to provide symptom management for patients who are dying or experiencing the sequelae of serious illness and its *** propose an East-West integrative palliative care model using non-drug therapies,such as acupuncture,diet,exercise,and stress management that shift the paradigm from suppressing the symptoms of illness to addressing both the root cause of the symptoms and the imbalance and declining homeostatic reserve that perpetuate these *** whole-person model expands the reach of palliative care,prolonging a better quality of life and allowing the patient to maintain as many activities as possible by preventing symptoms and improving *** this approach we reframe the dialogue such that patients are"living better"rather than"dying better"when faced with serious illness or *** this article,we provide an overview of the principles of palliative care,integrative medicine,and the novel area of integrative palliative care,and propose an East-West integrative palliative care model that incorporates and broadens the scope of these existing approaches.

关键词： person-centered model palliative care integrative medicine traditional Chinese medicine acupuncture symptom management cost-effectiveness reframing healthcare

study of TiO_2 thin films on si substrate by the photoacoustic elastic bending method

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science China(Physics,Mechanics & Astronomy) 2013年第7期56卷 1285-1293页

作者： TOdOROVi dragan M RABAsOVi Mihailo d MARKUsHEV dragan d FRANKO Mladen TANGAR Urka Lavreni institute for Multidisciplinary Research University of Belgrade institute of Physics University of Belgrade Laboratory for Environmental Research University of Nova Gorica

The quantitative photoacoustic investigation of different TiO2 thin films on si substrates is presented using the elastic bending method. Photoacoustic signal amplitude and phase spectra versus modulation frequency were measured and analyzed using different sample thicknesses. Within the proposed method particular attention is given to the analysis of optical, thermal, elastic and structural sample parameters. Considerable focus is devoted to the fitting procedure of experimental results using the two-layer sample theoretical model. Characteristics of previously developed photoacoustic apparatus are discussed, attempting to search the ideal experimental conditions which can provide a good signal-to-noise ratio and sensitivity.

关键词： photoacoustic TiO2 thin films

incremental Linear discriminant Analysis dimensionality Reduction and 3d dynamic Hierarchical Clustering WsNs

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Computer systems science & Engineering 2022年第11期43卷 471-486页

作者： G.divya Mohana priya M.karthikeyan K.Murugan department of Electronics and Communication Engineering Tamilnadu College of EngineeringKarumathampattiCoimbatore641659India department of Electronics and Communication Engineering KPR Institute of Engineering and TechnologyAvinashiCoimbatore RdArasurCoimbatoreTamilnadu641048India

Optimizing the sensor energy is one of the most important concern in Three-dimensional(3d)Wireless sensor Networks(WsNs).An improved dynamic hierarchical clustering has been used in previous works that computes optimum clusters count and thus,the total consumption of energy is ***,the computational complexity will be increased due to data dimension,and this leads to increase in delay in network data transmission and *** solving the above-mentioned issues,an efficient dimensionality reduction model based on incremental Linear discriminant Analysis(iLda)is proposed for 3d hierarchical clustering *** major objective of the proposed work is to design an efficient dimensionality reduction and energy efficient clustering algorithm in 3d hierarchical clustering *** iLda approach consists of four major steps such as data dimension reduction,distance similarity index introduction,double cluster head technique and node dormancy *** protocol differs from normal hierarchical routing protocols in formulating the Cluster Head(CH)selection *** to node’s position and residual energy,optimal cluster-head function is generated,and every CH is elected by this *** a 3d spherical structure,under the same network condition,the performance of the proposed iLda with improved dynamic Hierarchical Clustering(idHC)is compared with distributed Energy-Efficient Clustering(dEEC),Hybrid Energy Efficient distributed(HEEd)and stable Election Protocol(sEP)*** is observed that the proposed iLda based idHC approach provides better results with respect to Throughput,network residual energy,network lifetime and first node death round.

关键词： Lifetime energy optimization hierarchical routing protocol data transmission reduction incremental linear discriminant analysis(iLda) three-dimensional(3d)space wireless sensor network(WsN)

Vascular units as advanced living materials for bottom-up engineering of perfusable 3d microvascular networks

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Bioactive Materials 2024年第8期38卷 499-511页

作者： i.d.Orge H.Nogueira Pinto M.A.silva s.J.Bidarra s.A.Ferreira i.Calejo R.Masereeuw s.M.Mihail C.C.Barrias i3s-instituto de investigaçao e inovaçao em saúde Universidade do PortoPortoPortugal iNEB-instituto de Engenharia Biomedica Universidade do PortoPortoPortugal iCBAs-instituto de Ciencias Biomedicas Abel salazar Universidade do PortoPortoPortugal division of Pharmacology Utrecht Institute for Pharmaceutical SciencesUtrecht UniversityUtrechtthe Netherlands

The timely establishment of functional neo-vasculature is pivotal for successful tissue development and regen-eration,remaining a central challenge in tissue *** this study,we present a novel(micro)vascular-ization strategy that explores the use of specialized“vascular units”(VUs)as building blocks to initiate blood vessel formation and create perfusable,stroma-embedded 3d microvascular networks from the *** demonstrate that VUs composed of endothelial progenitor cells and organ-specific fibroblasts exhibit high angiogenic potential when embedded in fibrin *** leads to the formation of VUs-derived capillaries,which fuse with adjacent capillaries to form stable microvascular beds within a supportive,extracellular matrix-rich fibroblastic *** a custom-designed biomimetic fibrin-based vessel-on-chip(VoC),we show that VUs-derived capillaries can inosculate with endothelialized microfluidic channels in the VoC and become ***,VUs can establish capillary bridges between channels,extending the microvascular network throughout the entire *** VUs and intestinal organoids(iOs)are combined within the VoC,the VUs-derived capillaries and the intestinal fibroblasts progressively reach and envelop the *** promotes the formation of a supportive vascularized stroma around multiple iOs in a single *** findings un-derscore the remarkable potential of VUs as building blocks for engineering microvascular networks,with ver-satile applications spanning from regenerative medicine to advanced in vitro models.

关键词： Engineered tissue Organ-on-chip Microtissue spheroid endothelial colony-forming cells

Numerical investigation and potential tunability scheme on e^+e^- and π^+π^- stimulated pair creation from vacuum using high intensity laser beams

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High Power Laser science and Engineering 2016年第4期4卷 1-7页

作者： i.Ploumistakis s.d.Moustaizis i.Tsohantjis Technical University of Crete Laboratory of Matter Structure and Laser Physics National and kapodistrian University of Athens Faculty of PhysicsDepartment of Nuclear and Particle Physics

Numerical estimates for electrons and mesons particle–antiparticle creation from vacuum in the presence of strong electromagnetic fields are derived, using the complete probability density relation of Popov's imaginary time method(Popov, JETP Lett. 13, 185(1971); sov. Phys. JETP 34, 709(1972); sov. Phys. JETP 35, 659(1972); Popov and Marinov, sov. J. Nucl. Phys. 16, 449(1973); JETP Lett. 18, 255(1974); sov. J. Nucl. Phys. 19, 584(1974));(Popov,Phys. Let. A 298, 83(2002)), and within the framework of an experimental setup like the E144(Burke et al., Phys. ***. 79, 1626(1997)). The existence of crossing point among pair creation efficiency curves of different photon energies and the role of odd/even multiphoton orders in the production rates are discussed. Finally a kind of tunability process between the two creation processes is discussed.

关键词： high intensity lasers multiphoton processes pair production