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Assessing the Potential of Innovative Clay Designs for Enhancing Oyster Reef Restoration

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Open Journal of Marine science 2025年第1期15卷 35-58页

作者： Natacha M. s. Juste-Poinapen Quentin Gentili Natanael Hazel George C. Birch Camille saurel Oyster Heaven Rotterdam The Netherlands Nucleus Rotterdam The Netherlands National Institute of Aquatic Resources Danish Shellfish Centre Technical University of Denmark Nykobing Mors Denmark

The restoration of European flat oyster (Ostrea edulis) population is critical for biodiversity and ecosystem services recovery. This study evaluates the potential of innovative clay substrates, developed and patented by Oyster Heaven, as cost-effective and degradable alternatives for large-scale oyster reef restoration. Field trials conducted in an oyster aquaculture site and hatchery experiments under controlled conditions assessed the larvae settlement efficiency, microbial biofilm composition, and environmental influences. Results showed significantly lower larvae recruitment on clay prototypes and spat collectors used as control, in wild conditions, with environmental factors such as temperature and hypoxia playing a key role. In the hatchery, larvae preferred oyster shells (17,174 ± 659 spats/m2) over clay prototypes (2917 ± 111 spats/m2) and spat collectors (1451 ± 160 spats/m2). Microbial analysis revealed a shift towards Cyanobacteria and Woeseia species, with Pseudoalteromonadaceae, a genus previously linked to both stimulating and inhibiting larvae settlement, detected only on clay surfaces. Despite challenges, the clay prototypes demonstrated potential as sustainable substrates for restoration, particularly in managed “spats-on-reefs” strategies. This research highlights the importance of environmental monitoring, microbial interactions, and substrate optimization in enhancing restoration success for O. edulis populations. Further investigations are recommended to refine clay designs and assess their broader applicability under variable environmental conditions.

关键词： Oyster Restoration Larvae settlement Artificial substrate Microbial Biofilm Ostrea edulis

Compositional suitability Assessment and New Classification of Lateritic soils for Road Construction: Case of Materials from the Thies Region in senegal

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Journal of Geoscience and Environment Protection 2025年第1期13卷 71-88页

作者： Baye Oumar Diop Ignace Gbaguidi Papa Goumbo Lo seynabou sène Aminata Cisse Makhaly Ba Khadym Niang cole suprieure Polytechnique Universit Cheikh Anta Diop Dakar Senegal Ecole Nationale suprieure des Mines et de la Gologie (ex-IsT) Universit Cheikh Anta Diop Dakar Senegal Laboratoire National de Rfrence dans le domaine du Btiments et des Travaux Publics (LNR-BTP)1 Dakar Senegal Agence des travaux et de Gestion des Routes (AGEROUTE)2 Dakar Senegal UFR sciences de lIngnieur Universit Iba Der Thiamf de This This Sngal

Lateritic soils are found over large areas in tropical countries where their suitability for road engineering is a real concern, both compositionally and mechanically. Mineralogical and geochemical characterization, and profile description were carried out on Pliocene gravel lateritic soils from the Thies region to assess their suitability for road construction. These soils were sampled in Lam-Lam, Mont Rolland, Pout, Ngoundiane and sindia borrow pits in that region. Minerals that make up these studied materials are quartz, kaolinite, hematite and goethite, identified by X-Ray Diffraction and confirmed with Infrared spectroscopy. This mineralogy is characteristic of lateritic soils which are concretionary structure and are formed in well-drained tropical regions like that of Thies. According to the chemical results, these gravel lateritic soils are poor in organic matter, OM 2/(Al2O3 + Fe2O3) Diop ternary diagram for classifying lateritic soils. Therefore, Thies materials are ferruginous lateritic soils, Al2O3/Fe2O3 swelling clay (kaolinite) and rich in gravelly nodules, s/CEC s a result, these soils are compositionally suitable for road construction. These appreciated mineralogical, geochemical and pedological properties can now help overcome compositional challenges well before determining the bearing capacity of lateritic materials. This mechanical strength, which largely depends on their composition, is decisive in defining the optimal conditions for using lateritic materials in road geotechnics.

关键词： Lateritic Gravel Mineralogy Geochemistry soil Profile Thies

serological surveillance for sARs-CoV-2 antibodies among students,faculty and staff within a large university system during the pandemic

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World Journal of Virology 2025年第1期14卷 99-107页

作者： Marcos G Pinheiro Gabriela G O Alves Maria Eduarda R Conde sofia L Costa Regina C s sant’Anna Isa M F Antunes Mônica C Carneiro Fabio s Ronzei Julia C scaffo Felipe R Pinheiro Lialyz s Andre Helvecio C Povoa Valéria T Baltar Fabíola Giordani Eduarda s Hemerly Gisele C Alexandre Karla C de Paula Márcio Watanabe Antonio Claudio L da Nóbrega Jackeline Christiane P Lobato Fabio Aguiar-Alves Laboratory of Molecular Epidemiology and Biotechnology Rodolpho Albino University LaboratoryFluminense Federal UniversityNiterói 24241000Rio de JaneiroBrazil Estácio de sáUniversity Nova Friburgo 28611135Rio de JaneiroBrazil Pathology Program Medicine schoolFluminense Federal UniversityNiterói 24070090Rio de JaneiroBrazil Department of Pharmaceutical sciences Lloyd L.Gregory School of PharmacyPalm Beach Atlantic UniversityWest Palm BeachFL 33401United States Health Institute of Nova Friburgo Fluminense Federal UniversityNova Friburgo 28613001Rio de JaneiroBrazil Department of Epidemiology and Biostatistics Institute of Collective Health(ISC)Fluminense Federal UniversityNiterói 24033900Rio de JaneiroBrazil Institute of Physical Education Fluminense Federal UniversityNiterói 24020005Rio de JaneiroBrazil Department of statistics Fluminense Federal UniversityNiterói 24210200Rio de JaneiroBrazil Department of Physiology and Pharmacology Fluminense Federal UniversityNiterói 24210130Rio de JaneiroBrazil

BACKGROUND At the end of December 2019,the world faced severe acute respiratory syndrome-coronavirus 2(sARs-CoV-2),which led to the outbreak of coronavirus disease 2019(COVID-19),associated with respiratory *** virus has shown significant challenges,especially for senior citizens,patients with other underlying illnesses,or those with a sedentary *** tests conducted early on have helped identify how the virus is transmitted and how to curb its *** study hypothesis was that the rapid serological test for sARs-CoV-2 antibodies could indicate the immunoreactive profile during the COVID-19 pandemic in a university *** To conduct active surveillance for serological expression of anti-sARs-CoV-2 antibodies in individuals within a university setting during the COVID-19 *** This sectional study by convenience sampling was conducted in a large university in Niteroi-RJ,Brazil,from March 2021 to July *** study population consisted of students,faculty,and administrative staff employed by the university.A total of 3433 faculty members,60703 students,and 3812 administrative staff were invited to *** were gathered through rapid serological tests to detect immunoglobulin(Ig)M and IgG against ***χ²or Fisher's exact test was used to conduct statistical analysis.A 0.20 significance level was adopted for variable selection in a multiple logistic regression model to evaluate *** A total of 1648 individuals were enrolled in the *** proportion of COVID-19 positivity was 164/1648(9.8%).The adjusted logistic model indicate a positive association between the expression of IgM or IgG and age[odds ratio(OR)=1.16,95%CI:1.02-1.31](Ps who had been in contact with a COVID-19-positive case(OR=3.49,95%CI:2.34-5.37)(Pse who had received the COVID-19 vaccine(OR=2.33,95%CI:1.61-3.35)(Psocial isolation(OR=0.59,95%CI:0.41-0.84)(Psho

关键词： serological surveillance sARs-CoV-2 antibodies COVID-19 serological rapid test Risk factors for COVID-19

Exploring the therapeutic potential of glucagon-like peptide 1agonists in metabolic disorders

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World Journal of Gastroenterology 2025年第4期31卷 169-175页

作者： Adrián Cortés-Martín Julio Plaza-Diaz Promoting Fitness and Health Through Physical Activity Research Group Sport and Health University Research InstituteUniversity of GranadaGranada 18016AndalusiaSpain school of Health sciences Universidad Internacional de La RiojaLogroño 26006La RiojaSpain

This article comments on the work by soresi and *** authors have stated that one of the most novel and promising treatments for metabolic dysfunction-associated steatotic liver disease(MAsLD)is the use of glucagon-like peptide 1 receptor agonists,especially when used in combination ***,despite their notable efficacy,these drugs were not initially designed to target MAsLD *** a groundbreaking development,the Food and Drug Administration has recently approved resmetirom,the first treatment specifically aimed at reducing liver fibrosis in metabolic-associated ***,an orally administered,liver-directed thyroid hormone beta-selective agonist,acts directly on intrahepatic pathways,enhancing its therapeutic potential and marking the beginning of a new era in the treatment of ***,the integration of lifestyle modifications into liver disease management is an essential component that should be considered and *** incorporating dietary changes and regular physical exercise into treatment,patients may achieve improved outcomes,reducing the need for pharmacological interventions and/or improving treatment *** a complement to medical therapies,lifestyle factors should not be overlooked in the broader strategy for managing MAsLD.

关键词： Glucagon-like peptide 1 agonists Liver diseases Metabolic dysfunctionassociated steatotic liver disease Metabolic health Pharmacotherapy Diet Gut microbiome Physical exercise Lifestyle Non-alcoholic fatty liver disease

Wafer-scale MOCVD growth of monolayer M0s2 on sapphire and siO2

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Nano Research 2019年第10期12卷 2646-2652页

作者： Huanyao Cun Michal Macha HoKwon Kim Ke Liu Yanfei Zhao Thomas LaGrange Andras Kis Aleksa ndra Radeno vic Laboratory of Nanoscale Biology Institute of BioengineeringEcole Polytechnique Federate de Lausanne(EPFL)1015 LausanneSwitzerland Nanoscale Electronics and structures Electrical Engineering InstituteEcole Poly technique Federate de Lausanne(EPFL)1015 LausanneSwitzerland Nanoscale Electronics and structures Institute of Materials Science and EngineeringEcole Poly technique Federate de Lausanne(EPFL)1015 LausanneSwitzerland Interdisciplinary Center for Electron Microscopy(CIME) Ecole Polytechnique Federale de Lausanne(EPFL)1015 LausanneSwitzerland

High-quality and large-scale growth of monolayer molybdenum disulfide(Mos2)has caught intensive attention because of its potential in many applications due to unique electronic ***,we report the wafer-scale growth of high-quality mono layer Mos2 on singlecrystalline sapphire and also on siO2 substrates by a facile metal-organic chemical vapor deposit!on(MOCVD)*** to growth,an aqueous solution of sodium molybdate(Na2MoO4)is spun onto the substrates as the molybdenum precursor and diethyl sulfide((C2H5)2s)is used as the sulfur precursor duri ng the *** grown Mos2 films exhibit crystal I i nity,good electrical performa nee(electro n mobility of 22 cm2·V^-1·s^-1)and structural continuity maintained over the entire *** sapphire substrates are reusable for subsequent *** same method is applied for the synthesis of tungsten disulfide(Ws2).Our work provides a facile,reproducible and cost-efficient method for the scalable fabricati on of high-quality mono layer Mos2 for versatile applicati ons,such as electro nic and optoelectr onic devices as well as the membranes for desalination and power generation.

关键词： molybdenum disulfide two-dimensional(2D)materials metal-organic chemical vapor deposition(MOCVD) wafer-scale fabrication

Dietary processed former foodstuffs for broilers:impacts on growth performance,digestibility,hematobiochemical profiles and liver gene abundance

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Journal of Animal science and Biotechnology 2025年第1期16卷 364-376页

作者： Karthika srikanthithasan Marta Gariglio Elena Diaz Vicuna Edoardo Fiorilla Barbara Miniscalco Valeria Zambotto Eleonora Erika Cappone Nadia stoppani Dominga soglia Federica Raspa Joana Nery Andrea Giorgino Roser sala Andrés Luis Martínez Marínz Josefa Madrid sanchez Achille schiavone Claudio Forte Department of Veterinary sciences University of TurinGrugliascoItaly Animal Nutrition and Welfare service(sNiBA) Department of Animal and Food SciencesUniversitat Autònoma de BarcelonaBarcelonaSpain Departamento de Producción Animal Universidad de CórdobaCórdobaSpain Department of Animal Production University of MurciaMurciaSpain

Background The present experiment aimed to evaluate the effects of commercially processed former foodstuffs(cFF)as dietary substitutes of corn,soybean meal and soybean oil on the growth performance,apparent total tract digestibil-ity(ATTD),hematobiochemical profiles,and liver gene abundance in broiler *** hundred one-day-old male ROss-308 chicks were assigned to 4 dietary groups(5 replicates of ten birds per replicate)according to their average body weight(BW,38.0±0.11 g).All groups received a two-phase feeding program:starter,d 1–12 and grower,d 12–*** control group(cFF0)was fed a standard commercial feed based on corn,soybean meal and soybean *** other three groups received diets in which the feed based on corn,soybean meal,and soybean oil was partially replaced with cFF at a substitution level of 6.25%(cFF6.25),12.5%(cFF12.5)or 25%(cFF25)for the following 33 *** The growth performance data showed no differences in BW or average daily gain among groups,although the average daily feed intake decreased during the grower period(12–33 d)and over entire experimental period(1–33 d)in a linear manner as the cFF inclusion level rose(P=0.026),positively affecting the gain to feed ratio(P=0.001).The ATTD of dry matter of the cFF-fed groups were greater with respect to control group and increased throughout the experimental period,whereas the ATTD of ether extract linearly decreased with increasing levels of cFF-fed groups compared with control group and throughout the experimental period(Pse in the heterophil to lymphocyte ratio,serum cholesterol,triglycerides and alanine-aminotransferase were observed with increasing dietary levels of cFF(Ps were observed in lipoprotein lipase or sterol regulatory element binding transcription factor gene *** The results of this experiment demonstrate that it is possible to incorporate cFF into nutritionally balanced diets for broiler ch

关键词： Alternative feed Broiler chicken Digestibility Former foodstuff Gene abundance Growth performance

Prevalence of RUNX1 gene alterations in de novo adult acute myeloid leukemia

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World Journal of Experimental Medicine 2025年第1期15卷 65-79页

作者： Hoda M Abd El-Ghany Mona s El Ashry Mona s Abdellateif Ahmed Rabea Nada sultan Omnia Y Abd El Dayem Department of Clinical Pathology Faculty of MedicineCairo UniversityCairo 11976Al QāhirahEgypt Department of Clinical Pathology National Cancer InstituteCairo UniversityCairo 11976Al QāhirahEgypt Department of Cancer Biology National Cancer InstituteCairo UniversityCairo 11976Al QāhirahEgypt Department of Medical Oncology National Cancer InstituteCairo UniversityCairo 11976Al QāhirahEgypt

BACKGROUND Acute myeloid leukemia(AML)is a complicated disease with uncontrolled hematopoietic precursor proliferation induced by various genetic ***-related transcription factor-1(RUNX1)is commonly disrupted by chromosomal translocations in hematological *** To characterize RUNX1 gene rearrangements and copy number variations in newly diagnosed adult AML patients,with an emphasis on the impact of clinical and laboratory features on the *** Fluorescence in situ hybridization was used to test RUNX1 gene alterations in 77 newly diagnosed adult AML ***1,FLT3/ITD,FLT3/TKD,and KIT mutations were tested by *** clinical and laboratory findings were studied in relation to RUNX1 *** RUNX1 abnormalities were detected by fluorescence in situ hybridization in 41.6%of patients:20.8%had translocations,22.1%had amplification,and 5.2%had *** prevailed in AML-M2(P=0.019)with a positive expression of myeloperoxidase(P=0.031),whereas deletions dominated in M4 and M5 subtypes(P=0.008)with a positive association with CD64 expression(P=0.05).The modal chromosomal number was higher in cases having amplifications(P=0.007)and lower in those with deletions(P=0.008).RUNX1 abnormalities were associated with complex karyotypes(Psive of NPM1 *** 44 months of follow-up,RUNX1 abnormalities affected neither patients’response to treatment nor overall *** RUNX1 abnormalities were mutually exclusive of NPM1 ***1 abnormalities affected neither patients’response to treatment nor overall survival.

关键词： Acute myeloid leukemia Deletion Disease-free survival Fluorescence in-situ hybridization Karyotyping RUNX1

sickle Crisis Precipitated by Pneumonia: A Diagnostic and Therapeutic Challenge

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Journal of Biosciences and Medicines 2025年第1期13卷 255-263页

作者： David Fernando Ortiz-Pérez Luisa María Petro-Noriega Margarita Rosa Burgos-Peña Marlon José Rosado-Mendoza santiago sánchez-Rojas Cristina De Jesús Portillo-Monterrosa Daniel de Jesús González-Villarreal Juan Pablo de la Ossa Díaz John sebastián Osorio-Muñoz Manuel Esteban Ortiz Pérez Ana María García-suárez Department of Internal Medicine Cartagena del Mar Medical Center Cartagena Colombia Internal Medicine Program Universidad del Sin Cartagena Colombia Faculty of General Medicine Universidad del Sin Cartagena Colombia Faculty of General Medicine Universidad Surcolombiana Neiva Colombia Faculty of General Medicine Universidad de Sucre Sincelejo Colombia Faculty of General Medicine Universidad Libre Barranquilla Colombia Faculty of General Medicine Fundacin Universitaria Navarra Neiva Colombia Faculty of General Medicine Universidad de Cartagena Cartagena Colombia

sickle cell anemia (sCA) is a prevalent genetic disorder primarily affecting individuals of African descent and populations in malaria-endemic regions, with significant global public health implications. sickle cell crises are their most common acute complication, characterized by episodes of intense pain and systemic manifestations that impair quality of life and impose a high healthcare burden. We present the case of a 19-year-old male diagnosed with sCA since the age of two, who developed a sickle cell crisis precipitated by right basal pneumonia. The patient exhibited sudden-onset, cyclic lumbar pain with progressive dyspnea. Initial management included multimodal pain control, volume optimization, and targeted antimicrobial therapy to achieve clinical stabilization. This case underscores the importance of a comprehensive approach to managing sickle cell crises, addressing both symptomatic relief and the prevention and treatment of complications. It also highlights the need for public health strategies promoting early diagnosis, access to disease-modifying therapies such as hydroxyurea, and interdisciplinary follow-up to mitigate the socioeconomic and clinical impact of sCA.

关键词： sickle Cell Anemia sickle Cell Crisis Pain Management Pneumonia Hydroxyurea

多变量预后模型改善结直肠癌复发预测：PROsPe CT试验

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国际医学放射学杂志 2025年第1期 115-116页

作者： V.Goh s.Mallett V.Boulter R.Glynne-Jones s.Khan s.Lessels 李晗

摘要目的改善预后预测以指导个性化治疗的需求仍未能解决。通过前瞻性研究CT、遗传和免疫组织化学标志物，以改善对结直肠癌复发的预测。方法该多中心试验（Is

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