检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

东印度洋水体输运的季节变化及相关盐度变化

南京信息工程大学学报（自然科学版） 2020年第4期12卷 472-482页

作者： L.A.A.n.Wickramas.n.he 王卫强刘雨 M.K.Abeyratne W.C.Hemamali K.B.s.s.J.Ekanayake 中国科学院南海海洋研究所热带海洋环境国家重点实验室广州510301 中国科学院大学北京100049 南方海洋科学与工程广东省实验室广州511458 中国科学院南海生态环境工程创新研究院广州510301 卢胡纳大学理学院马塔拉81000斯里兰卡

利用20年(1992-2012年)的ECCO2模式模拟数据,主要研究了东印度洋(EIO)水体输运的季节变化.在EIO选取3个断面,分别为赤道、80°E和6°n.研究结果表明,跨赤道和80°E的季节输运主体部分大致相补偿.跨赤道的大部分水体输运局限在上层100 m... 详细信息

利用20年(1992-2012年)的ECCO2模式模拟数据,主要研究了东印度洋(EIO)水体输运的季节变化.在EIO选取3个断面,分别为赤道、80°E和6°n.研究结果表明,跨赤道和80°E的季节输运主体部分大致相补偿.跨赤道的大部分水体输运局限在上层100 m,80°E的水体输运具有复杂结构,与显著的季风流、Wyrtki Jets(WJs)、赤道潜流(EUC)等有关.6°n上层水体净输运较小,但存在较强的边界流和相对较弱的内区流.纬向流的显著变化发生在80°E.在季风盛行季节,由于WJs减弱,赤道附近的水体输运以西向的梯度流为主,上层100 m的其余区域则主要受季风流控制.同样,由于EUC减弱,西向的梯度流与次表层东向的EUC之间也存在转换.在季风转换季节,季风流减弱,WJs与EUC分别在上层100 m和次表层占主导地位.此外,本研究还讨论了与季风流、WJs和EUC相关的盐水和暖水交换,有助于了解研究区域内温度和盐度的水平和垂直结构.

关键词：东印度洋水体输运盐度分布

在线全文

学校读者我要写书评

暂无评论

2型糖尿病及高血压患者的循环黏附分子水平

世界核心医学期刊文摘（心脏病学分册） 2005年第7期1卷 38-39页

作者： Boulbou M.s. Koukoulis G.n. Makri E.D. 杜缓 Department of Physiology Medical SchoolUniversity of Thessaly 22 Papakyriazi 41222 Larissa Greece

Background: Risk factors for atherosclerosis such as hypertension, type 2 diabetes, obesity and dyslipidemia affect endothelial function and stimulate adhesion molecules expression. The aim of the study was to examine endothelial activation in type 2 diabetes and hypertension as indicated by adhesion molecule levels and further to investigate whether the coexistence of the above conditions has a different effect. Methods: serum levels of soluble E-selectin, ICAM-1 and VCAM-1 were measured in 17 hypertensive type 2 diabetic patients(DM-HY), 32 normotensive type 2 diabetic patients(DM), 11 hypertensive nondiabetic patients(HY) and 15 healthy subjects. Results: In diabetic patients(either DM-HY or DM), soluble E-selectin levels were significantly increased compared to healthy subjects(pn HY patients, both sE-selectin(66.44±71.59 vs. 29.42±15.56 ng/ml, p=0.033) and sVCAM-1(1529±433.33 vs. 1027±243.56 ng/ml, p=0.03) levels were found significantly higher compared to healthy subjects(pstence of diabetes and hypertension(DM-HY) did not have an additive effect on circulating adhesion molecules levels compared with the levels observed in either diabetes or hypertension. systolic and diastolic blood pressure(BP) were independent factors correlated respectively with sE-selectin and sVCAM-1 levels(R=0.454, p=0.034 and R=0.578, p=0.005) in nondiabetic subjects(hypertensive and normotensive). Conclusions: Type 2 diabetes mellitus and hypertension induce endothelial activation as indicated by elevated levels of soluble adhesion molecules. This effect is.n.t different when comorbidity is pres.n..

关键词：内皮细胞选择素黏附分子脂质异常伴发病

儿童多动脉炎:对110例患儿的多中心调查结果

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（儿科学分册） 2005年第3期1卷 39-40页

作者： Ozen s. Anton J. Arisoy n. 王一飞

对通过中小动脉的坏死性血管炎或者血管造影所得的数据诊断为结节性多动脉炎(PAn)的患儿进行分析。要求儿科医生将患儿分为4个提意的儿童PAn 组。全世界21个儿科中心的110例患儿参与了试验。受试女孩和男孩的比率为56:54。其平均年龄为9... 详细信息

对通过中小动脉的坏死性血管炎或者血管造影所得的数据诊断为结节性多动脉炎(PAn)的患儿进行分析。要求儿科医生将患儿分为4个提意的儿童PAn 组。全世界21个儿科中心的110例患儿参与了试验。受试女孩和男孩的比率为56:54。其平均年龄为9.05±3.57岁。病例分类如下:33例皮肤PAn,占30%;5例典型的PAn伴有乙肝表面抗原阳性,占4.6%;9例抗中性粒细胞胞浆抗体(AnCA)相关的成人显微镜下多动脉炎,占8.1%;63例系统性PAn,占57.2%。皮肤PAn 是局限在皮肤骨骼肌肉系统中的疾病。所有乙肝表面抗原相关PAn都经过肾血管造影诊断,且大部分病例都进行了抗病毒治疗。显微镜下多动脉炎患儿存在肺和肾病,或两部位中至少一种疾病。87%的患儿存在AnCA, 2例患儿最终发展为终末期肾衰。典型系统性PAn患儿存在多系统损伤,大部分都有全身的症状和急性期反应物含量增加。皮质类固醇和环磷酰胺是免疫治疗的首选药物。总死亡率为1.1%。PAn患儿之间存在着明显的差异,与成人相比,儿童的PAn有不同的临床表现、较高的生存率和较低的复发率。

关键词：动脉炎多系统损伤乙肝表面抗原坏死性血管炎 AnCA 终末期肾衰病例分类复发率皮质类固醇急性期反应物

在线全文

学校读者我要写书评

暂无评论

噪音与心肌梗死风险

世界核心医学期刊文摘（心脏病学分册） 2006年第5期2卷 32-33页

作者： Willich s.n.Wegscheider K stallmann M Keil T. 王海玲 Institute for social Medicine Epidemiology and Health Economics Charité University Medical Centre 10098Berlin Germany

Aims: Chronic noise exposure is associated with adverse pathophysiological effects and may contribute to the progression of cardiovascular disease. We, therefore, determined the risk of noise for the incidence of myocardial infarction. Methods and results: In a case-control study, 4115 patients(3054 men, 56± 9 years; 1061 women, 58± 9 years) consecutively admitted to all 32 major hospitals in Berlin with confirmed diagnosis of acute myocardial infarction were enrolled from 1998 to 2001 in the noise and Risk of Myocardial Infarction(naRoMI) study. Controls were matched for gender, age, and hospital. In standardized interviews, information was obtained on environmental and work noise annoyance. The sound levels of environmental and work noise were assessed us.n. traffic noise maps as proxy and international standards for workplaces, respectively. In multivariate logistic regression models, the adjusted odds ratios of noise variables were determined. There was a marginally increased risk of myocardial infarction associated with annoyance by environmental noise in women(adjusted odds ratio 1.47, 95% confidence interval 0.95- 2.25, P=0.081) but not in men, and not associated with annoyance by work noise. Environmental sound levels were associated with increased risk in men and women(odds ratios 1.46, 1.02- 2.09, P=0.040 and 3.36, 1.40- 8.06, P=0.007) and work sound levels in men only(1.31, 1.01- 1.70, P=0.045). Conclusion: Chronic noise burden is associated with the risk of myocardial infarction. The risk increase appears more closely associated with sound levels than with subjective annoyance. Further investigation of the gender-related risk of noise exposure may aid in improving prevention.

关键词：急性心肌梗死发生风险噪音病例对照研究病理生理学心血管疾病国际标准工作场所交通噪声副作用

在鼓泡塔中平板电极和扩张金属电极上的质量传递

在线全文

学校读者我要写书评

暂无评论

氯碱工业 1989年第5期25卷 23-27页

作者： s.PIOVAnO O.n.CAVATORTA U.BHM 金丽华锦西化工研究所

本文测定了置于鼓泡塔中心处的平板电极和扩张金属电极上的质量传递速率,在电解液物理性质不同和改变气体速度的条件下,对不同类型的扩张金属进行了研究,在有些情况下,得出传质系数的增量超过平板电极值的100%。不同体系、均存在无量纲... 详细信息

本文测定了置于鼓泡塔中心处的平板电极和扩张金属电极上的质量传递速率,在电解液物理性质不同和改变气体速度的条件下,对不同类型的扩张金属进行了研究,在有些情况下,得出传质系数的增量超过平板电极值的100%。不同体系、均存在无量纲关系。术语A 平板网眼孔径 D 扩散系数Dc 塔直径 g 重力加速度Ga 加利略数 gl^3/υ~2 Gr 格拉肖夫数 gΔQL^3/QL^2K 传质系数 L 电极高度r 径向位置 R 塔半径Re 雷诺数 RhVs/γ Rh 液压半径ε/(?)sc 施密特数 L/D sh 西尔乌得数 KL/DVs 表面速度 C 气泡空隙百分数εM 扩张金属孔隙率υ动态粘度Q 密度 (?)单位体积上的电极面积ψ单位网面积上的电极面积1、绪论多年来,在化学工业中,已经把鼓泡塔用作吸收器、分离器、反应器和电化学电解槽等。

关键词：鼓泡塔电解槽电极质量传递

循环游离DnA水平监测对乙型肝炎肝硬化失代偿期患者预后评估的临床价值

在线全文

学校读者我要写书评

暂无评论

上海医学 2021年第4期44卷 231-236页

作者：杨兆利白红英闫道杰济南市人民医院感染二科山东济南271100 济南市第二疾病预防控制中心艾滋病防治科

目的观察血清循环游离DnA(cfDnA)水平对乙型肝炎肝硬化失代偿期患者预后评估的临床价值。方法将112例乙型肝炎肝硬化失代偿期患者根据Child-Pugh分级标准分为A级组(39例)、B级组(31例)和C级组(42例);根据是否出现上消化道出血分为出血组... 详细信息

目的观察血清循环游离DnA(cfDnA)水平对乙型肝炎肝硬化失代偿期患者预后评估的临床价值。方法将112例乙型肝炎肝硬化失代偿期患者根据Child-Pugh分级标准分为A级组(39例)、B级组(31例)和C级组(42例);根据是否出现上消化道出血分为出血组(48例)和未出血组(64例);根据肝静脉压力梯度(HVPG)分为高压力组(>20 mmHg,1 mmHg=0.133 kPa,50例)、中压力组(15~20 mmHg,29例)和低压力组(10~nA水平。分析112例患者的临床资料,采用Cox比例风险回归模型进行单因素和多因素分析得出独立危险因素。根据ROC曲线分析确定血清cfDnA水平的截断值,采用Kaplan-Meier法进行生存分析,log-rank检验比较组间生存差异。结果不同Child-Pugh分级组患者血清cfDnA水平均显著高于对照组(P值均nA水平随着Child-Pugh分级加重而显著升高(P值均nA水平均显著高于对照组(P值均nA水平显著高于未出血组(PnA水平均显著高于对照组(P值均nA水平显著升高(P值均nA水平是影响乙型肝炎肝硬化失代偿期患者预后的独立危险因素(PnA水平最佳截断值为3406.34μg/L。64例患者cfDnA水平>3406.34μg/L,48例≤3406.34μg/L。高cfDnA水平组患者24和48个月累积生存率分别为78.1%和45.3%,分别显著低于低cfDnA水平组(89.6%和68.8%,P值均nA水平与乙型肝炎肝硬化失代偿期患者预后相关,通过检测cfDnA来判断乙型肝炎肝硬化失代偿期患者预后具有较高的临床价值。

关键词：循环游离DnA 乙型肝炎肝硬化失代偿期预后 Child-Pugh分级上消化道出血肝静脉压力梯度

兰尼单抗治疗新生血管性老年性黄斑变性的Ⅰ/Ⅱ期多中心临床对照多剂量研究

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（眼科学分册） 2006年第10期2卷 50-51页

作者： Heier J.s. Antoszyk A.n. Pavan P.R. 刑咏新 Ophthalmic Consultants of Boston BostonMAUnited States Dr.

Objective:To assess safety of repeated intravitreal injections of ranibizumab in treating neovascular age-related macular degeneration(AMD),and to assess changes in visual acuity(VA)and AMD lesion ***:Multicenter,controlled,open-label,clinical ***:sixty-four patients with subfoveal predominantly or minimally classic AMD-related choroidal ***:In part 1,subjects were randomized to monthly intravitreal ranibizumab for 3 months(4 injections of 0.3 mg or 1 injection of 0.3 mg followed by 3 injections of 0.5 mg;n=53)or usual care(UC;n=11).In part 2,subjects could continue their regimen for 3 additional months or cross over to the alternative *** Outcome Measures:Adverse events(AEs),intraocular pressure(IOP),VA,and lesion characteristics assessed by fluorescein angiography and fundus ***:Of the 64 randomized subjects,62 completed the 6-month *** of 25 subjects(80%)randomized to 0.3 mg,and 22 of 28 subjects(79%)randomized to 0.5-mg ranibizumab in part 1 continued on that treatment in part 2;9 of 11(82%)subjects randomized to UC in part 1 crossed over to ranibizumab treatment in part *** most common AEs with ranibizumab were reversible inflammation and minor injection-site *** AEs were iridocyclitis,endophthalmitis,and central retinal vein occlusion(1 subject each).Postinjection,IOP increased transiently in 22.6% of ranibizumab-treated eyes in parts 1 and *** 4 ranibizumab injections(day 98),mean(± standard deviation)VA had increased 9.4± 13.3 and 9.1± 17.2 letters in the 0.3-and 0.5-mg groups,respectively,but had decreased 5.1± 9.6 letters with *** part 2(day 210),VA increased from baseline 12.8± 14.7 and 15.0± 14.2 letters in subjects continuing on 0.3 and 0.5 mg,*** acuity improved from baseline ≥ 15 letters in 26%(day 98)and 45%(day 210)of subjects initially randomized to and continuing on ranibizumab,respectively,and areas of leakage and s

关键词：老年性黄斑变性单抗治疗玻璃体内注射眼底照相病变特征荧光血管造影临床对照试验视网膜下积液