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Chinese Physics C 2024年第4期48卷 6-13页

作者： Y.mahmoud H.Abdallah M.T.Hussein s.Elgammal Centre for theoretical physics The British University in EgyptEgypt Physics Department Faculty of ScienceCairo UniversityEgypt

In this study,we conducted a search for dark matter using a part of the data recorded by the CMs experiment during run-I of the LHC in 2012 with a center of mass energy of 8 TeV and an integrated luminosity of 11.6 fb−*** data were gathered from the CMs open *** matter,in the framework of the simplified model(mono-Z′),can be produced from proton-proton collisions in association with a new hypothetical gauge boson,Z′.Thus,the search was conducted in the dimuon plus large missing transverse momentum *** benchmark scenario of mono-Z′,which is known as light vector,was used for interpreting the CMs open *** evidence of dark matter was observed,and exclusion limits were set on the masses of dark matter and Z′at 95%confidence level.

关键词： dark matter large hadron collider CMs open data search for new physics dark fermion

Anthropogenic mineral generation and its potential resource supply:The case of niobium

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science China Earth sciences 2024年第8期67卷 2583-2591页

作者： Xianlai ZENG Moisés Gómez mahmoud BAKrY Yong GENG Jinhui LI school of Environment Tsinghua UniversityBeijing 100084China school of Environmental science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China school of International and Public Affairs Shanghai Jiao Tong UniversityShanghai 200030China

The strategy of carbon neutrality is reshaping the global landscape of resource flow and *** the final sink of geological minerals,the proliferated anthropogenic minerals,also called secondary resources,play an increasingly important role in resource supply *** is a critical metal that lacks full concern for its *** fundamental principle of niobium circularity is to recycle and maintain the material as close to the manufacturing process as *** we estimate the niobium-containing applications lost at their end-of-life,underscoring the imperative to minimize such ***,we elucidate the extraction processes for scrap and alloy quantities throughout the industry's *** from anticipated waste generated by the majority of niobium applications,a forecast indicates a potential loss of approximately 168 kt by 2090 in the absence of ***,with a recycling efficiency of 90%for niobium,the projected loss diminishes to approximately 16 *** delve into the significance of niobium's circular economy and explore various aspects that demand further investigation for a seamless transition from linear to circular practices.

关键词： Niobium Anthropogenic mineral Circular economy recycling sustainability

Astrophysical s-factor and reaction rate for 15N(p,γ)16O within the modified potential cluster model

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Chinese Physics C 2024年第4期48卷 130-145页

作者： s.B.Dubovichenko A.s.Tkachenko r.Ya.Kezerashvili N.A.Burkova B.M.Yeleusheva Fesenkov Astrophysical Institute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate school and University Center City University of New York10016 New YorkUSA al-Farabi Kazakh National University 050040 AlmatyKazakhstan

We study radiative p^(15)N capture on the ground state of ^(16)O at stellar energies within the framework of a modified potential cluster model(MPCM)with forbidden states,including low-lying *** investigation of the ^(15)N(p,γ0)^(16)O reaction includes the consideration of ^(3)s_(1) resonances due to E1 transitions and the contribution of the ^(3)P_(1) scattering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the astrophysical low-energy s-factor,and the extrapolated s(0)turned out to be within 34.7−40.4 keV·*** important role of the asymptotic constant(AC)for the ^(15)N(p,γ0)16O process with interfering ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances is elucidated.A comparison of our calculation for the s-factor with existing experimental and theoretical data is addressed,and a reasonable agreement is *** reaction rate is calculated and compared with the existing *** has negligible dependence on the variation of AC but shows a strong impact of the interference of ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances in reference to the CNO Gamow windows,especially at low *** estimate the contribution of cascade transitions to the reaction rate based on the exclusive experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cascade transitions is observed from T_(9)>0.3 and reaches the maximum factor~1.3 at T_(9)=*** present the Gamow energy window and a comparison of rates for radiative proton capture reactions ^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O obtained in the framework of the MPCM and provide the temperature windows,prevalence,and significance of each process.

关键词： low and astrophysical energies p^(15)N system thermonuclear reaction rate potential cluster model CNO-cycle

Predicting Energy Consumption Using stacked LsTM snapshot Ensemble

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Big Data Mining and Analytics 2024年第2期7卷 247-270页

作者： Mona Ahamd Alghamdi Abdullah s.A.L-Malaise AL-Ghamdi mahmoud ragab Information systems Department Faculty of Computing and Information Technology(FCIT)King Abdulaziz University(KAU)Jeddah 21589Kingdom of Saudi Arabia Information systems Department FCITKAUJeddah 21589Kingdom of Saudi Arabiaand also with School of EngineeringComputing and DesignDar Al-Hekma UniversityJeddah 22246Kingdom of Saudi Arabia Information Technology Department FCITKAUJeddah 21589Kingdom of Saudi Arabiaand also with Mathematics DepartmentFaculty of ScienceAl-Azhar UniversityNaser City 11884Egypt

The ability to make accurate energy predictions while considering all related energy factors allows production plants,regulatory bodies,and governments to meet energy demand and assess the effects of energy-saving *** energy consumption falls within normal parameters,it will be possible to use the developed model to predict energy consumption and develop improvements and mitigating measures for energy *** objective of this model is to accurately predict energy consumption without data limitations and provide results that are easily *** proposed model is an implementation of the stacked Long short-Term Memory(LsTM)snapshot ensemble combined with the Fast Fourier Transform(FFT)and *** and Berard’s Individual Household Electric-Power Consumption(IhePC)dataset incorporated with weather data are used to analyse the model’s accuracy with predicting energy *** model is trained,and the results measured using root Mean square Error(rMsE),Mean Absolute Error(MAE),Mean Absolute Percentage Error(MAPE),and coefficient of determination(r^(2))metrics are 0.020,0.013,0.017,and 0.999,*** stacked LsTM snapshot ensemble performs better than the compared models based on prediction accuracy and minimized *** results of this study show that prediction accuracy is high,and the model’s stability is high as *** model shows that high levels of accuracy prove accurate predictive ability,and together with high levels of stability,the model has good interpretability,which is not typically accounted for in ***,this study shows that it can be inferred.

关键词： energy consumption prediction Artificial Intelligence(AI) Deep Learning(DL) snapshot ensemble

Co-doped Ni_(3)s_(2) nanosheet array: A high-efficiency electrocatalyst for alkaline seawater oxidation

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Nano research 2024年第3期17卷 1050-1055页

作者： Meng Yue Xun he shengjun sun Yuntong sun Mohamed s.Hamdy Mhamed Benaissa Alsamani A.M.salih Jun Liu Xuping sun College of Chemistry Chemical Engineering and Materials ScienceShandong Normal UniversityJinan 250014China Institute of Fundamental and Frontier sciences University of Electronic Science and Technology of ChinaChengdu 610054China Department of Chemistry College of ScienceKing Khalid UniversityP.O.Box 9004Abha 61413Saudi Arabia Department of Chemical Engineering College of EngineeringUniversity of Ha’ilP.O.Box 2440Ha’il 81441Saudi Arabia Department of Otolaryngology-head&Neck surgery West China HospitalSichuan UniversityChengdu 610041China

Developing efficient and durable oxygen evolution reaction(OEr)catalysts holds great promise for green hydrogen production via seawater electrolysis,but remains a ***,we report a Co-doped Ni_(3)s_(2) nanosheet array on Ni foam(Co-Ni_(3)s_(2)/NF)as a high-efficiency OEr electrocatalyst for *** alkaline conditions,Co-Ni_(3)s_(2)/NF requires an overpotential of only 368 mV to drive 100 mA·cm^(–2),superior to Ni_(3)s_(2)/NF(385 mV).Besides,it exhibits at least 50-h continuous electrolysis.

关键词： Co doping Ni_(3)s_(2)nanosheet array oxygen evolution reaction seawater electrolysis electrocatalyst

Electro-optic tuning in composite silicon photonics based on ferroionic 2D materials

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Light(science & Applications) 2024年第5期13卷 852-864页

作者： Ghada Dushaq solomon serunjogi srinivasa r.Tamalampudi mahmoud rasras Department of Electrical and Computer Engineering New York University Abu DhabiP.O.Box 129188Abu DhabiUnited Arab Emirates NYU Tandon school of Engineering New York UniversityNew YorkNYUSA

Tunable optical materials are indispensable elements in modern optoelectronics,especially in integrated photonics circuits where precise control over the effective refractive index is essential for diverse ***-dimensional materials like transition metal dichalcogenides(TMDs)and graphene exhibit remarkable optical responses to external ***,achieving distinctive modulation across short-wave infrared(sWIr)regions while enabling precise phase control at low signal loss within a compact footprint remains an ongoing *** this work,we unveil the robust electro-refractive response of multilayer ferroionic two-dimensional CuCrP2s6(CCPs)in the near-infrared wavelength *** integrating CCPs into silicon photonics(siPh)microring resonators(Mrr),we enhance lightmatter interaction and measurement sensitivity to minute phase and absorption *** show that electrically driven Cu ions can tune the effective refractive index on the order of 2.8×10−3 rIU(refractive index unit)while preserving extinction ratios and resonance ***,these devices exhibit low optical losses and excellent modulation efficiency of 0.25 *** with a consistent blue shift in the resonance wavelengths among all devices for either polarity of the applied *** results outperform earlier findings on phase shifters based on ***,our study demonstrates distinct variations in electro-optic tuning sensitivity when comparing transverse electric(TE)and transverse magnetic(TM)modes,revealing a polarization-dependent response that paves the way for diverse applications in light *** combined optoelectronic and ionotronic capabilities of two-terminal CCPs devices present extensive opportunities across several *** potential applications range from phased arrays and optical switching to their use in environmental sensing and metrology,optical imaging systems,and neuromorphic systems in light-sensitive artificial synapses.

关键词： tuning polarization refractive

Insulin therapy in type 2 diabetes: Insights into clinical efficacy, patient-reported outcomes, and adherence challenges

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World Journal of Diabetes 2024年第5期15卷 828-852页

作者： mahmoud Emad-Eldin Gehan F Balata Eman A Elshorbagy Mona s Hamed Mohamed s Attia Department of Pharmacy Practice Faculty of PharmacyZagazig UniversityZagazig HFQM+872Al-Sharqia GovernorateEgypt Department of Pharmacy Practice Faculty of PharmacyHeliopolis UniversityCairo 44519Egypt Department of Pharmaceutics Faculty of PharmacyZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Department of Internal Medicine Faculty of MedicineZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Department of Community at Faculty of Medicine Zagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt

Insulin therapy plays a crucial role in the management of type 2 diabetes as the disease *** the past century,insulin formulations have undergone significant modifications and bioengineering,resulting in a diverse range of available insulin *** products show distinct pharmacokinetic and pharmacodynamic ***,various insulin regimens have em-erged for the management of type 2 diabetes,including premixed formulations and combinations of basal and bolus *** utilization of different insulin regimens yields disparate clinical outcomes,adverse events,and,notably,patient-reported outcomes(PrOs).PrOs provide valuable insights from the patient’s perspective,serving as a valuable mine of information for enhancing healthcare and informing clinical *** to insulin therapy,a critical patient-reported outcome,significantly affects clinical outcomes and is influenced by multiple *** review provides insights into the clinical effectiveness of various insulin preparations,PrOs,and factors impacting insulin therapy adherence,with the aim of enhancing healthcare practices and informing clinical decisions for individuals with type 2 diabetes.

关键词： Adherence Diabetes Insulin Patient-reported outcomes Pharmacokinetic Pharmacodynamic

Detection and clearance in Alzheimer’s disease: leading with illusive chemical, structural and morphological features of the targets

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Neural regeneration research 2024年第3期19卷 497-498页

作者： Luís Gales i3s−Instituto de Investigação e Inovação em saúde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAs−Instituto de Ciências Biomédicas Abel salazar Rua de Jorge Viterbo FerreiraPortoPortugal

Highly specific interactions between biomolecules,such as antigen-antibody,protein-ligand,or nucleic acid base pair complementary are on the basis of the organization of complex *** same principles may be tentatively used in molecular medicine for diagnosis and therapeutics.A molecule can be designed to selectively bind a protease and thereby inhibit the production of a peptide that forms toxic aggregates in the brain or an antibody may be produced to bind specifically to that peptide for detection or clearance ***,interference in biological systems is not that *** a start there is the inhibition of the physiological role of the protease;moreover,several cleavage fragments may be produced,which may continue to diverge due to putative post-translational modification and self-assembly processes,hiding the toxic target in a“soup”of peptide species varying in size,structure and chemical composition.A perspective of the current status and challenges in targeting peptide species for diagnosis and treatment in the context of Alzheimer’s disease is given.

关键词： Alzheimer diagnosis thereby

FEA-based Geometrical Modification of switched reluctance Motor for radial Force reduction

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Chinese Journal of Electrical Engineering 2024年第1期10卷 124-135页

作者： rani s Jayapragash r school of Electrical Engineering Vellore Institute of TechnologyChennai 600127India

switched reluctance motors(srMs)are becoming increasingly popular in the automotive sector owing to their robust ***,srMs are preferred particularly for EV applications owing to their fault tolerance,magnet-free structure,and high power/torque *** main concerns of srM compared to other machines include torque ripple and *** primary cause of vibration is the radial force created by the srM.A geometry-based modification of the srM to reduce the radial force without significantly changing the average torque produced is *** primary goal is to design a 4-phase,8/6 srM with a lower radial *** possible geometrical alterations are proposed:one with square windows and the other with circular holes on the rotor *** windows are sized and positioned to avoid flux *** criteria are developed for the optimal window size and *** element analysis(FEA)modelling of the srM is used to validate its *** FEA results are compared with the performance parameters obtained using the analytical *** the multiphysics design tool ANsYs to obtain the natural frequencies and associated deformations through modal *** to the conventional geometry,the radial force is significantly reduced by providing windows.

关键词： 8/6 srM radial force modal analysis FEA analysis natural frequencies srM with windows

Chemotherapy induces breast cancer stem cell enrichment through repression of glutathione s-transferase Mu

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Genes & Diseases 2024年第2期11卷 528-531页

作者： Jing he Yiran Yu Yilin he Jie he Guangyu Ji Haiquan Lu The second Hospital and Advanced Medical research Institute Cheeloo College of MedicineShandong UniversityJinanShandong 250012China Department of Nursing The First Affiliated Hospital of Shandong First Medical UniversityJinanShandong 250014China school of Medicine Xinjiang Medical UniversityUrumqiXinjiang 830054China school of Medicine Binzhou Medical UniversityYantaiShandong 264003China Oncology Department Jinan Zhangqiu District People's HospitalJinanShandong 250200China Key Laboratory for Experimental Teratology of the Ministry of Education Cheeloo College of MedicineShandong UniversityJinanShandong 250012China Center for reproductive Medicine Shandong UniversityJinanShandong 250012China

Triple-negative breast cancer(TNBC)has aggressive characteristics as exemplified by the high risk of recurrence,metastasis,and patient mortality.1 Cytotoxic chemotherapy may reduce tumor burden initially,but leave behind chemo-resistant breast cancer stem cells(BCsCs)that lead to tumor recurrence and metastasis.2 Chemotherapy induces BCsC enrichment through the activation of glutathione biosynthesis pathways,which increases intracellular glutathione levels and specifies the BCsC phenotype through complicated downstream signaling pathways.3 Glutathione s-transferases(GsTs),a superfamily(which contains seven cytosolic classes:Alpha,Kappa,Mu,Omega,Pi,Theta,and Zeta,and one microsomal class MGsTs)of phase Il enzymes that catalyze the conjugation of glutathione with electrophilic compounds,play a critical role in detoxification and chemotherapy resistance of cancer ***,the role of GsTs in the regulation of BCsCs is largely elusive.

关键词： chemotherapy breast metastasis