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Associations between parental adherence to healthy lifestyles and cognitive performance in offspring:A pros.ective cohort study in China

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Chinese Medical Journal 2024年第6期137卷 683-693页

作者： Rongxia Lv Yuhui Huang siyi Huang shiyi Wu siwen Wang Guangyu Hu Yanan Ma Peige song Jorge e.Chavarro s.V.subramanian Chunling Lu Zhihui Li Changzheng Yuan school of Public Health the Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310058China Department of Nutrition Harvard T.H.Chan School of Public HealthBostonMA 02115USA Institute of Medical Information/Center for Health Policy and Management Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Biostatistics and epidemiology School of Public HealthChina Medical UniversityShenyangLiaoning 110122China Department of social and Behavioral sciences Harvard T.H.Chan School of Public HealthBostonMA 02115USA Division of Global Health equity Brigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115USA Department of Global Health and social Medicine Harvard Medical SchoolBostonMA 02115USA Vanke school of Public Health Tsinghua UniversityBeijing 100084China Department of Global Health and Population Harvard T.H.Chan School of Public HealthBostonMA 02115USA

Background:Previous studies have reported associations of s.ecific maternal and paternal lifestyle factors with offspring’s cognitive development during early *** study aimed to investigate the pros.ective associations between overall parental lifestyle and offspring’s cognitive performance during adoles.ence and young adulthood in ***:We included 2531 adoles.ents aged 10-15 years at baseline in 2010 from the China Family Panel studies.A healthy parental lifestyle score(ranged 0-5)was constructed based on the following five modifiable lifestyle factors:smoking,drinking,exercise,s.eep,and *** estimating equation models were used to examine the association between baseline parental healthy lifestyle scores and offspring’s fluid and crystallized intelligence in subsequent years(2012,2014,2016,and 2018).Results:Offspring in the top tertile of parental healthy lifestyle scores performed better in overall fluid intelligence(multivariable-adjus.ed β=0.53,95%confidence interval[CI]:0.29-0.77)and overall crystallized intelligence(multivariable-adjus.ed β=0.35,95%CI:0.16-0.54)than those in the bottom tertile of parental healthy lifestyle *** results were similar after further adjustment for the offspring’s healthy lifestyle scores and persis.ed across the subgroups of parental socioeconomic ***,maternal and paternal healthy lifestyle scores were independently associated with better offspring’s cognitive performance,with significant contribution observed for paternal never-smoking,weekly exercise,and diversified *** both parents and offspring adhered to a healthier lifestyle,we observed the highest level of the offspring’s overall crystallized ***:Our study indicates that parental adherence to a healthier lifestyle is associated with significantly better offspring’s cognitive performance during adoles.ence and early adulthood,regardless of socioeconomic *** findings highlight the poten

关键词： Cohort study Parental healthy lifestyle Offspring Cognitive performance Intelligence Adoles.ence

POIssON PReCONDITIONING FOR seLF-ADJOINT eLLIPTIC PROBLeMs

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Journal of Computational Mathematics 2014年第5期32卷 560-578页

作者： houde Han Chunxiong Zheng Department of Mathematical sciences Tsinghua University Beijing 100084 China

In this paper, we formulate interface problem and Neumann elliptic boundary value problem into a form of linear operator equations with self-adjoint positive definite op- erators. We prove that in the discrete level the condition number of these operators is independent of the mesh size. Therefore, given a prescribed error tolerance, the classical conjugate gradient algorithm converges within a fixed number of iterations. The main computation task at each iteration is to solve a Dirichlet Poisson boundary value problem in a rectangular domain, which can be furnis.ed with fast Poisson solver. The overall computational complexity is.es.entially of linear scaling.

关键词： Fast Poisson solver Interface problem self-adjoint elliptic problem Conjugategradient method.

enhanced entropy generation and heat trans.er characteristics of magnetic nano-encapsulated phase change materials in latent heat thermal energy storage sys.ems

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Applied Mathematics and Mechanics.english edition) 2024年第6期45卷 1051-1070页

作者： P.s.ReDDY P.s.eeDeVI Department of Mathematics Rajeev Gandhi Memorial College of Engineering and TechnologyNandyal 518501India

The objective of the current study is to investigate the importance of entropy generation and thermal radiation on the patterns of velocity,isentropic lines,and temperature contours within a thermal energy storage device filled with magnetic nanoencapsulated phase change materials(NePCMs).The versatile finite element method(FeM)is implemented to numerically solve the governing *** effects of various parameters,including the viscosity parameter,ranging from 1 to 3,the thermal conductivity parameter,ranging from 1 to 3,the Rayleigh parameter,ranging from 102 to 3×10^(2),the radiation number,ranging from 0.1 to 0.5,the fusion temperature,ranging from 1.0 to 1.2,the volume fraction of NePCMs,ranging from 2%to 6%,the s.efan number,ranging from 1 to 5,the magnetic number,ranging from 0.1 to 0.5,and the irreversibility parameter,ranging from 0.1 to 0.5,are examined in detail on the temperature contours,isentropic lines,heat capacity ratio,and velocity ***,the heat trans.er rates at both the cold and hot walls are analyzed,and the findings are presented *** results indicate that the time taken by the NePCMs to transition from solid to liquid is prolonged inside the chamber region as the fusion temperatureθf ***,the contours of the heat capacity ratio Cr decrease with the increase in the s.efan number s.e.

关键词： volume fraction of nano-encapsulated phase change material(NePCM) radiation s.efan number heat capacity ratio entropy generation

engineering of efficient visible light photocatalysts:Ti_(1-x+y)Cu_(x)La_(y)O_(2)(x=0.03;y=0,0.005,0.01) compositions

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Journal of Rare earths 2024年第3期42卷 497-505,I0003页

作者： s.M.Yakout A.M.Yous.ef Inorganic Chemistry Department National Research Centre(NRC)El Buhouth StDokkiCairo12622Egypt

In dye-photocatalysis, widening the wavelengths absorption range of catalysts as well as aborting the recombination of the photoexcited charge carriers.electrons-holes pairs) are of paramount *** the current study, we report the photocatalytic characteristics of four compositions composed of TiO_(2),Ti_(0.97)Cu_(0.03)O_(2), Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders for two harmful dyes(Congo red and methylene blue). The X-ray diffraction technique verified the configuration of mixed anatase and rutile phases in pure TiO_(2)and Ti_(0.97)Cu_(0.03)O_(2)powders while Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders pos.ess anatase phase only. The changes of the band gap structure and dimensions of the unit cell volume of TiO_(2)confirm the substitution of Ti^(4+)sites by Cu^(2+)and La^(3+)ions. Remarkable widening of wavelengths absorption with formation of long absorption tails were found in TiO_(2)(3.13 e V) through insertion of La^(3+)plus Cu^(2+)ions. Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)samples.exhibit a visible light band gap of 2.3 and 2.7 e V, res.ectively. Based on seM images, incorporation of Cu^(2+)and La^(3+)ions influences the surface morphology of TiO_(2). The resulting Ti_(0.97)Cu_(0.03)O_(2), Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders present enhanced photocatalytic activity towards Congo red dye degradation compared to pure one under natural solar s.ectrum. The best Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)catalyst exhibits superior photocatalytic activity of 96% for 10 ppm CR dye in 20 min as well as above average photocatalytic efficiency of 63% for 30 ppm CR dye in 120 min. As well, it showed acceptable photodegradation activity of 52% for 30 ppm MB solution in 140 min of sunlight irradiation. The heightened photodegradation efficiency of Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)catalyst can be clarified in terms of higher ch

关键词： semiconductor TiO_(2) Rare earths Congo red Methylene blue solar s.ectrum Photodegradation

Mixing and matching sMXL proteins to fine-tune strigolactone responses

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Molecular Plant 2024年第8期17卷 1167-1169页

作者： Jenna e.Hountalas s.elley Lumba Department of Cell&sys.ems Biology University of Toronto25 Willcocks StreetTorontoON M5S 3B2Canada Centre for the Analysis of Genome evolution and Function University of Toronto25 Willcocks StreetTorontoON M5S 3B2Canada

A common mechanism in plant hormone signaling is hormonedependent degradation of downstream *** the case of strigolactone(sL)signaling,one group of sUPPRessOR OF MORe AXILLARY BRANCHes 2(MAX2)1-LIKe(sMXL)proteins undergoes hormone-dependent degradation,while another does not.A recent publication in Molecular Plant by Li et al.(2024)illustrates that mixing and matching a sMXL resistant to sL degradation with a sMXL sensitive to sL degradation finely tunes sL *** phenomenon could reflect a naturally occurring negative transdominance,which is a dominantnegative effect arising not from a mutant allele of the same gene but rather from a different gene altogether(Veitia,2007).This trans-acting protein attenuates sL-dependent degradation of the sMXL *** findings have exciting implications for how different sMXL combinations could result in a gradient of sL responses.

关键词： complex. matching degradation

Mathematical modeling and simulations of stress mitigation by coating polycrystalline particles in lithium-ion batteries

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Applied Mathematics and Mechanics.english edition) 2024年第6期45卷 947-962页

作者： N.IQBAL J.CHOI s.F.sHAH C.Lee s.Lee Department of Mechanical Roboticsand Energy EngineeringDongguk University-SeoulSeoul 04620Republic of Korea

A chemo-mechanical model is developed to investigate the effects on the stress development of the coating of polycrystalline Ni-rich LiNixMnyCo_(z)O_(2)(x≥0.8)(NMC)particles with poly(3,4-ethylenedioxythiophene)(PeDOT).The simulation results show that the coating of primary NMC particles significantly reduces the stress generation by efficiently accommodating the volume change associated with the lithium diffusion,and the coating layer plays roles both as a cushion against the volume change and a channel for the lithium transport,promoting the lithium distribution across the secondary particles more ***,the lower stiffness,higher ionic conductivity,and larger thickness of the coating layer improve the stress *** paper provides a mathematical framework for calculating the chemo-mechanical responses of anisotropic electrode materials and fundamental insights into how the coating of NMC active particles mitigates stress levels.

关键词： lithium-ion battery(LIB) polycrystalline particle coating finite element simulation Ni-rich LiNixMnyCo_(z)O_(2)(x>0.8)(NMC)

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Commentary on

Journal of sport and Health science 2024年第5期13卷 672-673页

作者： Barbara e.Ainsworth Zeyun Feng school of exercise and Health Shanghai University of SportShanghai 200438China

In Volume 13,Iss.e 1,of the Journal of sport and Health science,Herold et al.1 present a sys.ematic review and classification of digital and home-based physical training interventions aiming to support healthy cognitive *** interventions were reviewed:digital databases(i.e.,YouTube videos and apps),online clas.es,and technology-based exercise devices.e.g.,exergames).

关键词： cognitive games aging

High s.ed los.es in mountain birch(Betula pubes.ens ***)and developmental,ecological,and environmental correlates

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Journal of Plant ecology 2024年第4期17卷 56-69页

作者： Guorun Oskarsdottir Thora e.Thorhallsdottir Kristin svavarsdottir University of Iceland 102 ReykjavíkIceland Land and Forest Iceland ReykjavíkIceland

Plants typically experience great los.es from their reproductive potential represented by ovule production to the post-dis.ersal crop of viable *** examined s.ed density and viability in a founder population of mountain birch(Betula pubes.ens ***),aiming to quantify los.es at different stages and examine potential selection forces on the reproduction success of the founder generation of an isolated *** the time of the study(2017-2020),the population had recently reached reproductive maturity,following its colonization around 1990 through long-distance dis.ersal onto an early successional outwash plain in southeast *** densities were high,but 89% of apparently intact s.eds did not contain an embryo,despite being visually indistinguishable from filled *** evident los.es amounted to about 45% of the total s.ed crop and were mostly due to predation by the gall midge semudobia *** all los.es were accounted for,2.7% of the s.ed crop remained viable and *** limitation may partially explain the high incidence of empty *** flower production is compatible with the predator satiation hypothesis but cannot explain pre-dis.ersal *** adaptation to predation,masting,appears poorly developed in *** results suggest the presence of constraints on the reproduction potential of the new island population,that are more limiting than in neighbouring populations,and we discuss their developmental,ecological,and environmental correlates.

关键词： Betula pubes.ens ssp.tortuosa(Ledeb.)Nyman Iceland s.ed quality s.ed los.es semudobia betulae sub-arctic

Chasing sequencing Perfection: Marching Toward Higher Accuracy and Lower Costs

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GeNOMICs PROTeOMICs & BIOINFORMATICs 2024年第2期22卷 qzae024页

作者： Jia, Hangxing Tan, s.engjun Zhang, Yong e. Chinese Acad sci Inst Zool CAS Key Lab Zool Systemat & Evolut Beijing 100101 Peoples R China Chinese Acad sci Inst Zool State Key Lab Integrated Management Pest Insects & Beijing 100101 Peoples R China Univ Chinese Acad sci Beijing 100049 Peoples R China Chinese Acad sci CAS Ctr Excellence Anim Evolut & Genet Kunming 650223 Peoples R China

Next-generation sequencing (NGs), represented by Illumina platforms, has been an es.ential cornerstone of basic and applied research. However, the sequencing error rate of 1 per 1000 base pairs (10-3) represents a serious hurdle for research areas focusing on rare mutations, such as somatic mosaicism or microbe heterogeneity. By examining the high-fidelity sequencing methods developed in the past decade, we summarized three major factors underlying errors and the corresponding 12 strategies mitigating these errors. We then proposed a novel framework to classify 11 preexisting representative methods according to the corresponding combinatory strategies and identified 3 trends that emerged during methodological developments. We further extended this analysis to 8 long-read sequencing methods, emphasizing error reduction strategies. Finally, we suggest 2 promising future directions that could achieve comparable or even higher accuracy with lower costs in both NGs and long-read sequencing.

关键词： sequencing error High-fidelity sequencing Consensus sequencing single-molecule sequencing Rare mutation RARe MUTATIONs PARALLeL QUANTIFICATION eRRORs DAMAGe