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A comprehensive investigation on nonlinear vibration and bending characteristics of bio-inspired helicoidal laminated composite structures

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 81-100页

作者： s.sAURABH R.KIRAN d.sINGH R.VAIsH V.s.CHAUHAN school of Mechanical and Materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(IHsdT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the C0finite element method(FEM), and an in-house code is developed in the MATLAB environment to solve it numerically. Various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(Hs), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. Moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

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soft x-ray tomographic reconstruction of Heliotron J plasma for the study of magnetohydrodynamic equilibrium and stability

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Plasma science and Technology 2019年第6期21卷 72-78页

作者： s purohit Y sUZUKI s OHdACHI s YAMAMOTO sOKENdAI The Graduate University for Advanced Studies Toki Gifu 509-5292 Japan National Institute for Fusion science Toki Gifu 509-5292 Japan Institute of Advanced Energy Kyoto University Gokasho Uji Kyoto 611-0011 Japan

The preparation for an experimental soft x-ray tomography study on the Heliotron J (H-J) machine is carried out,with the objectives of evaluating the capability of the current soft x-ray tomographic system in terms of the identification of different mode structures and their poloidal rotation,and the axis shift with different plasma and machine parameters,and fixing the physics goals for the experimental *** preparations were carried out via a simulated soft x-ray data set arising from different plasma conditions,such as magnetic islands,low beta and high *** x-ray tomography (sXT) is performed by the discrete pixel method including singular value decomposition and Phillips-Tikhonov regularization,to obtain clear and smooth *** H-J soft x-ray tomography results from simulated soft x-rays for the equilibrium H-J plasma sensed the magnetic axis shift clearly and an estimate was also *** reconstruction for mode structure m =1/n =1 was obtained along with the realization of the poloidal rotation of the *** reconstruction for the m =2/n =1 mode was not very clear for the current soft x-ray diagnostic *** mode identification was not possible due to the lack of *** sXT from the current soft x-ray diagnostic on H-J,the magnetic axis shift can be estimated and the m =1/n =1 mode can be *** of higher poloidal modes is difficult with the current design.

关键词： Heliotron J tomography soft x-ray magnetohydrodynamics

substrate Evolution to Microstructural and Optoelectrical Properties of Evaporated Cds Thin Films Correlated with Elemental Composition

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Acta Metallurgica sinica(English Letters) 2021年第9期34卷 1307-1316页

作者： Anuradha purohit Himanshu s.L.Patel s.Chander M.s.dhaka department of Physics Mohanlal Sukhadia UniversityUdaipur 313001India department of Chemical sciences Indian Institute of Science Education and Research.Mohali 140306India Centre for Advanced study in Physics Department of PhysicsPanjab UniversityChandigarh 160014India

A typical high-e fficiency solar cell device needs the best lattice matching between different constituent layers to mitigate the open-circuit voltage loss. In the present work, the physical properties of Cds thin films are investigated where films with 100 nm thickness were fabricated on the different types of substrates viz. soda–lime glass, indium-doped tin oxide(ITO)-and fl uorine-doped tin oxide(FTO)-coated glass substrates, and silicon wafer using electron beam evaporation. The X-ray diffraction patterns confirmed that deposited thin films showed cubic phase and had(111) as predominant orientation where the structural parameters were observed to be varied with nature of substrates. The ohmic behaviour of the Cds films was disclosed by current–voltage characteristics, whereas the scanning electron microscopy micrograph revealed the uniform deposition of the Cds films with the presence of round-shaped grains. The elemental analysis confirmed the Cds films deposition where the Cd/s weight percentage ratio was changed with nature of substrates. The direct energy band gap was observed in the 1.63–2.50 eV range for the films grown on different substrates. The investigated properties of thin Cds layers demonstrated that the selection of substrate(in terms of nature) during device fabrication plays a crucial role.

关键词： Cds thin films substrate evolution E-beam evaporation Microstructural properties Optoelectrical properties

Ecological niche modelling of a critically endangered species Commiphora wightii (Arn.) Bhandari using bioclimatic and non-bioclimatic variables

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Ecological Processes 2023年第1期12卷 110-139页

作者： Manish Mathur Preet Mathur Harshit purohit ICAR-Central Arid Zone Research Institute Jodhpur 342003India Jodhpur Institute of Engineering and Technology JodhpurIndia Neal Analytics PuneMaharashtraIndia

Background The aim of this study is to examine the effects of four different bioclimatic predictors(current,2050,2070,and 2090 under shared socioeconomic Pathways ssP2-4.5)and non-bioclimatic variables(soil,habitat heterogeneity index,land use,slope,and aspect)on the habitat suitability and niche dimensions of the critically endangered plant species Commiphora wightii in *** also evaluate how niche modelling affects its extent of occurrence(EOO)and area of occupancy(AOO).Results The area under the receiver operating curve(AUC)values produced by the maximum entropy(Maxent)under various bioclimatic time frames were more than 0.94,indicating excellent model ***-bioclimatic characteristics,with the exception of terrain slope and aspect,decreased the accuracy of our ***,Maxent accuracy was the lowest across all combinations of bioclimatic and non-bioclimatic variables(AUC=0.75 to 0.78).With current,2050,and 2070 bioclimatic projections,our modelling revealed the significance of water availability parameters(BC-12 to BC-19,*** and seasonal precipitation as well as precipitation of wettest,driest,and coldest months and quarters)on habitat suitability for this ***,with 2090 projection,energy variables such as mean temperature of wettest quarter(BC-8)and isothermality(BC-3)were identified as governing *** salt,rooting conditions,land use type(grassland),characteristics of the plant community,and slope were also noticed to have an impact on this *** distribution modelling of this species in both its native(west-ern India)and exotic(North-east,Central Part of India,as well as northern and eastern Ghat)habitats,we were also able to simulate both its fundamental niche and its realized *** EOO and AOO analysis reflects the possibility of many new areas in India where this species can be planted and *** According to the calculated area under the various suitability classes,we can conclude

关键词： Commiphora wightii Critically endangered Maxent Habitat heterogeneity index Niche hypervolume

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Primary biliary cirrhosis: Pathophysiology, clinical presentation and therapy

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World Journal of Hepatology 2015年第7期7卷 926-941页

作者： Treta purohit Mitchell s Cappell division of Gastroenterology and Hepatology William Beaumont Hospital Oakland University William Beaumont school of Medicine

Primary biliary cirrhosis(PBC) is an autoimmune, slowly progressive, cholestatic, liver disease characterized by a triad of chronic cholestasis, circulating anti-mitochondrial antibodies(AMA), and characteristic liver biopsy findings of nonsuppurative destructive cholangitis and interlobular bile duct destruction. About 10% of PBC patients, however, lack AMA. A variant, called PBC-autoimmune hepatitis(AIH) overlap, is characterized by the above findings of PBC together with findings of elevated serum alanine aminotransferase, elevated serum immunoglobulin G, and circulating anti-smooth muscle antibodies, with liver biopsy demonstrating periportal or periseptal, lymphocytic, piecemeal necrosis. PBC is hypothesized to be related to environmental exposure in genetically vulnerable individuals. It typically occurs in middle-aged females. Prominent clinical features include fatigue, pruritis, jaundice, xanthomas, osteoporosis, and dyslipidemia. The Mayo Risk score is the most widely used and best prognostic system. Ursodeoxycholic acid is the primary therapy. It works partly by reducing the concentration and injury from relatively toxic bile acids. PBC-AIH overlap syndrome is treated with ursodeoxycholic acid and corticosteroids, especially budesonide. Obeticholic acid and fibrate are promising new, but incompletely tested, therapies. Liver transplantation is the definitive therapy for advanced disease, with about 70% 10-year survival after transplantation. Management of pruritis includes local skin care, dermatologist referral, avoiding potential pruritogens, cholestyramine, and possibly opioid antagonists, sertraline, or rifaximin. Management of osteoporosis includes life-style modifications, administration of calcium and vitamin d, and alendronate. statins are relatively safe to treat the osteopenia associated with PBC. Associated sjogren's syndrome is treated by artificial tears, cyclosporine ophthalmic emulsion to stimulate tear production; and saliva substitutes, c

关键词： Primary biliary cirrhosis Ursodeoxycholicacid Cirrhosis Liver transplantation Cholestatic liverdisease

Genomic Tools for the Impact Assessment of 'Hotspots' for Early Warning of MdR Threats

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Biomedical and Environmental sciences 2016年第9期29卷 656-674页

作者： Nishant A dafale Hemant J purohit Environmental Genomic division CSIR-National Environmental Engineering Research Institute

INTROdUCTION Antimicrobial resistance （AMR） has been a low-priority area of research in most developing countries even though it has much significant therapeutic value. The management of serious infections should include not only the treatment of patients but also the measures to ensure that microorganisms do not spread through hospital premises. Controlling the transfer of organisms among staff, patients, and the environment is important. Research related to antimicrobial use and resistance, regional variation, and intervention policies.

关键词： MdR gene Genomic Tools for the Impact Assessment of for Early Warning of MdR Threats Hotspots

Biochemical dissection of sTAT3 signaling in amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3229-3230页

作者： savina Apolloni Nadia d’Ambrosi department of Biology University of Rome Tor VergataRomeItaly

Amyotrophic lateral sclerosis(ALs)is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons,clinically marked by muscle atrophy and *** the clinical course is highly variable,the average time from the onset of symptoms to the need for respiratory support or death is 3-5 *** is the most prevalent motor neuron disease in adults,occurring at a rate of 2 per 100,000 individuals and affecting 5.4 per 100,000 individuals overall.

关键词： sTAT3 dissection sclerosis

diffusion dynamics and characterization of attogram masses in optically trapped single nanoparticles using laser-induced plasma imaging

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Nano Research 2023年第5期16卷 7470-7480页

作者： Pablo purohit Francisco J.Fortes Javier Laserna UMALAsERLAB Departamento de Química AnalíticaUniversidad de MálagaC/Jiménez Fraud 4Malaga 29010Spain Niels Bohr Institute University of CopenhagenBlegdamsvej 172100 CopenhagenDenmark

In the present work,a wavelength-selected plasma imaging analysis system is presented and used to track photons emitted from single-trapped nanoparticles in air at atmospheric *** isolated nanoentities were atomized and excited into plasma state using single nanosecond laser *** use of appropriate wavelength filters alongside time-optimized acquisition settings enabled the detection of molecular and atomic emissions in the *** photon detection efficiency of the imaging line resulted in a signal>400 times larger than the simultaneously-acquired dispersive spectroscopy *** increase in sensitivity outlined the evolution of diverse physicochemical processes at the single particle scale which included heat and momentum transfer from the plasma into the particle as wells as chemical *** imaging detection of excited fragments evidenced different diffusion kinetics and time frames for atoms and molecules and their influence upon both the spectroscopic emission readout and fabrication processes using the plasma as a ***,the origin of molecular species,whether naturally-occurring or derived from a chemical reaction in the plasma,could also be studied on the basis of compositional gradients found on the *** of detection for the inspected species ranged from tens to hundreds attograms,thus leading to an exceptional sensing principle for single nanoentities that may impact several areas of science and technology.

关键词： single nanoparticle inspection wavelength-selected laser-induced plasma imaging laser fabrication attogram characterization atomic/molecular diffusion

Assessing anthropogenic pressure and threats on Paeonia emodi *** Royle habitats in Garhwal Himalaya

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Journal of Mountain science 2023年第3期20卷 810-820页

作者： Praveen JOsHI Prem PRAKAsH Vijay Kant purohit department of Botany Govt.M.B.P.G.CollegeHaldwani 263641Indial High Altitude Plant Physiology Research Centre H.N.B.Garhwal Central UniversitySrinagar Garhwal 263671India

The Garhwal Himalaya is among the major repositories of immensely valuable wild edible plants and provides food security to the local *** the valuable plant species that grow in this region,Paeonia emodi(family Paeoniaceae)is an important wild edible species that found in temperate regions with an altitude range between 1800 and 2800 *** species is facing a severe threat to its sustainability due to overharvesting,habitat disturbances,and a lack of effort regarding *** the first time,this study investigated anthropogenic pressure,population decline perceptions in the natural habitat,and vulnerability assessment of *** under selected study sites(n=23 villages).A semi structured questionnaire was used to interview approximately 45%of the local inhabitants,including herbal practitioners(Vaidhyas or dais)of each *** the basis of demographic characteristics,the perceptions and responses of 464 local people were documented regarding potential causes of deterioration and feasible options for sustainable *** the weight survey method,we estimated the actual amount of collection based on personal interaction and direct *** order to determine the threats status,a rapid vulnerability assessment(RVA)was performed and were used based on the current exploitation and *** present study revealed that leaf(100%)was the most frequently harvested part,followed by stem(95.65%),seed(26.09%),root(21.74%)and flower(13.04%).The village Triyuginarayan and Pothivasa recorded the highest collection scores while the purpose of the collection was mostly edible(100%),medicinal(100%),and least commercial(8.70%).According to the literature review and the present survey,the RVA(total=21)is categorized as category II(intermediate side of the RVA index),indicating a degree of *** study revealed that *** faces extinction in the Garhwal *** this species through agro-production techniques may alleviate th

关键词： Anthropogenic pressure Conservational strategies Garhwal Himalaya Paeonia emodi Rapid vulnerability assessment Wild edibles