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Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

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neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： siva s.V.P.sakamuri Anil sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:Hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

Alternative Estimator in Dichotomous Randomized Response Technique

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Communications in Mathematics and statistics 2019年第4期7卷 383-400页

作者： O.s.Ewemooje F.b.Adebola g.n.Amahia Department of statistics Federal University of TechnologyAkureNigeria Department of statistics University of IbadanIbadanNigeria

Obtaining correct responses to sensitive questions in social and behavioural researches is an ancient problem in survey research with respondents misreporting on sensitive behaviours or giving false response to protect *** paper develops an alternative unbiased estimator by modifying the dichotomous randomized response technique model to tackle this *** proposed estimatorwas compared numerically with conventional ones by considering different practicable and suitable design *** model was also considered when sampling with unequal probabilities with or without *** was observed that the proposed estimator performs efficiently than the conventional *** the proposed model captures progressively more people involved in the sensitive attribute,the model outperforms other models ***,social and behavioural researchers can now obtain correct and valid responses from sensitive behavioural researches with ease in order to make informed and reliable decisions.

关键词： Dichotomous randomized response technique Efficiency sensitive behavioural attribute Unequal probability

Experimental study on microstructural and corrosion behaviors of friction stir processed steel with CoCrFeCuTi HEA reinforcement and effect of annealing

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science China Technological sciences 2025年第1期 233-250页

作者： s.Aravind KRIsHnA n.RADHIKA Alokesh PRAMAnIK n.JEYAPRAKAsH Department of Mechanical Engineering Amrita School of EngineeringAmrita Vishwa Vidyapeetham school of Civil and Mechanical Engineering Curtin University school of Mechanical and Electrical Engineering China University of Mining and Technology

The ability to perform against extreme corrosion environments in stainless steel depreciates under challenging conditions in industrial applications. This can be resolved by employing surface modification techniques to modify the surface with the required characteristics. The present study investigates the outcomes of friction stir processing of ss304 with CoCrFeCuTi high entropy alloy(HEA) as reinforcement and the property enhancements post-annealing. The synthesized CoCrFeCuTi HEA exhibited irregular fragments with 17 μm mean particle size and body centred cubic(bCC) phase. The microstructure of the processed surface revealed ultra-refined grains with a uniform distribution of HEA filler. The microstructures of the samples annealed at 400℃, 550℃, 700℃ and 850℃ for 2 h also showed significant grain growth and grain refinements. The processed sample with HEA reinforcement annealed at 700℃ exhibited enhanced microhardness and tensile strength by 63% and 0.88 times than that of the processed sample with HEA pre-annealing. The subsequent electrochemical corrosion test displayed better corrosion resistance for the HEA-processed and annealed sample. Hot corrosion tests at 900℃ showcased excellent resistance for the HEA processed and annealed samples by 14.92%, 12.75%, and 14.83% against the samples pre-annealed under three different salt mixtures, and the corroded surface was analyzed.

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Projective Hilbert modules and sequential approximations

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science China Mathematics 2025年第1期 137-168页

作者： Lawrence g.brown Huaxin Lin Department of Mathematics Purdue University Department of Mathematics East China Normal University Department of Mathematics University of Oregon shanghai Institute for Mathematics and Interdisciplinary sciences

We show that when A is a separable C*-algebra,every countably generated Hilbert A-module is projective（with bounded module maps as morphisms）.We also study the approximate extensions of bounded module *** the case where A is a σ-unital simple C*-algebra with strict comparison,and every strictly positive lower semicontinuous affine function on quasitraces can be realized as the rank of an element in the Cuntz semigroup,we show that the Cuntz semigroup is equivalent to unitarily equivalent classes of countably generated Hilbert A-modules if and only if A has stable rank one.

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Dynamics of the plane and solitary waves in a noguchi network:Effects of the nonlinear quadratic dispersion

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Chinese Physics b 2020年第3期29卷 105-111页

作者： s A T Fonkoua M s ngounou g R Deffo F b Pelap s b Yamgoue A Fomethe Unite de Recherche de Matiere Condensee d’Electronique et de Traitement du signal(UR-MACETs) Faculte des SciencesUniversite de DschangBP 67 DschangCameroun Unite de Recherche de Mecanique et de Modelisation des systemes Physiques(UR-2MsP) Faculte des SciencesUniversite de DschangBP 69 DschangCameroun Department of Physics Higher Teacher Training College BambiliUniversity of BamendaP.O.Box 39 BamendaCameroon

We consider a modified noguchi network and study the impact of the nonlinear quadratic dispersion on the dynamics of modulated waves. In the semi-discrete limit, we show that the dynamics of these waves are governed by a nonlinear cubic schrodinger equation. From the graphical analysis of the coefficients of this equation, it appears that the nonlinear quadratic dispersion counterbalances the effects of the linear dispersion in the frequency domain. Moreover, we establish that this nonlinear quadratic dispersion provokes the disappearance of some regions of modulational instability in the dispersion curve compared to the results earlier obtained by Pelap et al.(Phys. Rev. E 91 022925(2015)). We also find that the nonlinear quadratic dispersion limit considerably affects the nature, stability, and characteristics of the waves which propagate through the system. Furthermore, the results of the numerical simulations performed on the exact equations describing the network are found to be in good agreement with the analytical predictions.

关键词： noguchi network nonlinear quadratic dispersion modulational instability soliton

Effect of COOH-functionalized sWCnT addition on the electrical and photovoltaic characteristics of Malachite green dye based photovoltaic cells

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Journal of semiconductors 2014年第12期35卷 32-37页

作者： s.Chakraborty n.b.Manik Condensed Matter Physics Research Center Department of Physics Jadavpur University

We report the effect of COOH-functionalized single walled carbon nanotubes（COOH-sWCnT） on the electrical and photovoltaic characteristics of Malachite green（Mg） dye based photovoltaic cells. Two different types of photovoltaic cells were prepared, one with Mg dye and another by incorporating COOH-sWCnT with this dye. Cells were characterized through different electrical and photovoltaic measurements including photocurrent measurements with pulsed radiation. From the dark current–voltage（I–V） characteristic results, we observed a certain transition voltage（Vth/ for both the cells beyond which the conduction mechanism of the cells change sharply. For the Mg dye, Vthis 3.9 V whereas for COOH-sWCnT mixed with this dye, Vthdrops to 2.7 V. The device performance improves due to the incorporation of COOH-sWCnT. The open circuit voltage and short circuit current density change from 4.2 to 97 m V and from 108 to 965 A/cm2 respectively. Observations from photocurrent measurements show that the rate of growth and decay of the photocurrent are quite faster in the presence of COOH-sWCnT. This observation indicates a faster charge separation processes due to the incorporation of COOHsWCnT in the Mg dye cells. The high aspect ratio of COOH-sWCnT allows efficient conduction pathways for the generated charge carriers.

关键词： Mg dye COOH-sWCnT photovoltaic devices charge transport

Microstructure, properties and hot workability of M300 grade maraging steel

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Defence Technology（防务技术） 2018年第1期14卷 51-58页

作者： K.V.A.Chakravarthi n.T.b.n.Koundinya s.V.s.narayana Murty b.nageswara Rao Materials and Mechanical Entity Vikram Sarabhai Space Centre Research scholar Department of Mechanical Engineering K L University Department of Metallurgical Engineering and Materials science Indian Institute of Technology Department of Mechanical Engineering K L University

This paper presents isothermal uniaxial compression test results of M300 grade maraging steel over a wide range of temperatures(900 e1200℃) and strain rates(0.001 e100 s^(-1)) to examine hot deformability and concurrent microstructural evolution. Processing map is generated and indicated the optimum processing parameters in the temperature range of 1125℃-1200℃ and strain rate range of 0.001 e0.1 s^(-1). High values of the efficiency of power dissipation, microstructural observations and EbsD results indicate softening mechanism to be the occurrence of dynamic recrystallisation. Material constants in a constitutive relation are evaluated from the flow stress data useful in computer modelling.

关键词： Activation energy Constitutive relation Hot deformation M300 grade maraging steel Processing map

A theoretical investigation of the band alignment of type-I direct band gap dilute nitride phosphide alloy of gan_xAs_yP_(1-x-y)/gaP quantum wells on gaP substrates

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Chinese Physics b 2014年第7期23卷 640-644页

作者： O L nsal b gnül M Temiz Department of Engineering Physics University of Gaziantep

The gaP-based dilute nitride direct band gap material ga（nAsP） is gaining importance due to the monolithic integra- tion of laser diodes on si microprocessors. The major advantage of this newly proposed laser material system is the small lattice mismatch between gaP and si. However, the large threshold current density of these promising laser diodes on si substrates shows that the carrier leakage plays an important role in ga（nAsP）/gaP QW lasers. Therefore, it is necessary to investigate the band alignment in this laser material system. In this paper, we present a theoretical investigation to optimize the band alignment of type-I direct band gap ganxAsyP1-x-y/gaP QWs on gaP substrates. We examine the effect of nitrogen （n） concentration on the band offset ratios and band offset energies. We also provide a comparison of the band alignment of type-I direct band gap ganxAsyP1-x-y/gaP QWs with that of the ganxAsyP1-x-y/Al2ga1-2P QWs on gaP substrates. Our theoretical calculations indicate that the incorporations of n into the well and AI into the barrier improve the band alignment compared to that of the gaAsP/gaP QW laser heterostructures.

关键词： quantum well band alignment carrier confinement dilute nitride phosphide alloy

Diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects

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neural Regeneration Research 2025年第8期20卷 2218-2230页

作者： Rahul Mittal Keelin McKenna grant Keith Evan McKenna Joana R.n.Lemos Jeenu Mittal Khemraj Hirani Diabetes Research Institute University of Miami Miller School of MedicineMiamiFLUSA Department of Otolaryngology University of Miami Miller School of MedicineMiamiFLUSA Herbert Wertheim College of Medicine Florida International UniversityMiamiFLUSA school of Medicine and Public Health University of WisconsinMadisonWIUSA

neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this *** peripheral neuropathy,a common complication of diabetes,is characterized by nerve damage due to high blood sugar levels that lead to symptoms,such as pain,tingling,and numbness,primarily in the hands and *** aim of this systematic review was to evaluate the efficacy of neuromodulatory techniques as potential therapeutic interventions for patients with diabetic peripheral neuropathy,while also examining recent developments in this *** investigation encompassed an array of neuromodulation methods,including frequency rhythmic electrical modulated systems,dorsal root ganglion stimulation,and spinal cord *** systematic review suggests that neuromodulatory techniques may be useful in the treatment of diabetic peripheral *** the advantages of these treatments will enable physicians and other healthcare providers to offer additional options for patients with symptoms refractory to standard pharmacologic *** these efforts,we may improve quality of life and increase functional capacity in patients suffering from complications related to diabetic neuropathy.

关键词： diabetes mellitus diabetic peripheral neuropathy neuromodulation neurostimulation therapy non-pharmacological treatment pain management