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Cavity-agnostic acoustofluidic manipulations enabled by guided flexural w.ves on a membrane acoustic w.veguide actuator

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Microsystems & Nanoengineering 2024年第2期10卷 153-171页

作者： Philippe Vachon srinivas Merugu Jaibir sharma Amit Lal Eldw.n J.ng Yul k.h Joshua E.-Y.Lee Chengk.o Lee Department of Electrical and Computer Engineering National University of SingaporeSingaporeSingapore Institute of Microelectronics Agency for ScienceTechnology and Research(A*STAR)SingaporeSingapore sonicMEMs Laboratory School of Electrical and Computer EngineeringCornell UniversityIthacaNYUSA school of Electrical and Data Engineering University of Technology SydneyUltimoNSWAustralia

This article presents an in-depth exploration of the acoustofluidic capabilities of guided flexural w.ves(GFw.)generated by a membrane acoustic w.veguide actuator(MAw.).By harnessing the potential of GFw.,cavity-agnostic advanced particle manipulation functions are achieved,unlock.ng new.avenues for microfluidic systems and lab-on-a-chip *** localized acoustofluidic effects of GFw. arising from the evanescent nature of the acoustic fields they induce inside a liquid medium are numerically investigated to highlight their unique and promising *** traditional acoustofluidic technologies,the GFw. propagating on the MAw.’s membrane w.veguide allow.for cavity-agnostic particle manipulation,irrespective of the resonant properties of the fluidic ***,the acoustofluidic functions enabled by the device depend on the flexural mode populating the active region of the membrane *** demonstrations using tw. types of particles include in-sessile-droplet particle transport,mixing,and spatial separation based on particle diameter,along w.th streaming-induced counter-flow.virtual channel generation in microfluidic PDMs *** experiments emphasize the versatility and potential applications of the MAw. as a microfluidic platform targeted at lab-on-a-chip development and show.ase the MAw.’s compatibility w.th existing microfluidic systems.

关键词： w.veguide fluid cavity

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Positron-Lithium Atom and Electron-Lithium Atom scattering systems at Intermediate and High Energies

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Chinese Physics Letters 2006年第7期23卷 1753-1756页

作者： k. Ratnavelu s. Y. ng Institute of Mathematical sciences Faculty of Science University of Malaya 50603 Kuala Lumpur Malaysia Department of Physics Faculty of Science National University of Singapore Singapore

The coupled-channel optical method is used to study positron scattering by atomic lithium at energies ranging from the ionization threshold to 60eV, The present method simultaneously treats the target channels and the positronium （Ps） channels in the coupled-channel method together w.th the continuum effects via an ab-initio optical potential. Ionization, elastic and inelastic cross sections in target channels, and the total cross section are also reported and compared w.th other theoretical and experimental data. A comparative study w.th the corresponding electron-lithium data is also reported.

关键词： CLOsE-COUPLIng THEORY HYDROGEN sCATTERIng CROss-sECTIONs COLLIsIONs

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Predictors of the placebo response in a nutraceutical randomized controlled trial for depression

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Journal of Integrative Medicine 2024年第1期22卷 46-53页

作者： Rosemary Arnold Jenifer Murphy-smith Chee H.ng David Mischoulon Gerard J.Byrne Chad A.Bousman Con stough Michael Berk.Jerome sarris Professorial Unit the Melbourne ClinicDepartment of PsychiatryUniversity of MelbourneRichmond 3121Australia Depression Clinical and Research Program Department of PsychiatryMassachusetts General HospitalHarvard Medical SchoolBostonMA 02115USA Faculty of Medicine Discipline of PsychiatryCentre for Clinical ResearchRoyal Brisbane&Women’s HospitalHerstonthe University of QueenslandBrisbane 4006Australia Departments of Medical Genetics PsychiatryPhysiology&Pharmacology and Community Health SciencesUniversity of CalgaryCalgaryAB T2N 1N4Canada Department of Psychiatry the University of MelbourneMelbourne 3052Australia Centre for Human Psychopharmacology Swinburne UniversityMelbourne 3122Australia The Institute for Mental and Physical Health and Clinical Translation School of MedicineBarwon HealthDeakin UniversityGeelong 3220Australia The Centre of Excellence in Youth Mental Health the University of MelbourneParkville 3052Australia Florey Institute of Neuroscience and Mental Health the University of MelbourneParkville 3052Australia NICM Health Research Institute Western Sydney UniversityWestmeadNSW 2145Australia

Objective The placebo response in depression studies is the change in symptoms amongst those w.o receive an inactive *** w.ll-designed randomized controlled trials(RCTs)of depression have a high proportion of placebo responders,w.th little understanding as to *** present study assesses characteristics associated w.th the placebo response in a nutraceutical trial w.th a large proportion of placebo *** This is a secondary analysis of a nutraceutical depression RCT w.ich identified no overall treatment benefit relative to placebo(n=69 in placebo group).w. investigated participant characteristics such as socio-demographics,clinical features,and recruitment methods,and their association w.th the placebo *** genetic polymorphisms w.re also *** response w.s measured based on change in Montgomery-Asberg Depression Rating scale *** association of these hypothesis-driven variables of interest and the placebo response w.s examined using linear mixed effects *** Greater levels of education,particularly pursuing post-high school education,better self-reported general health,marriage/de facto,greater improvement in the first trial w.ek.and more failed antidepressant therapies in the current depressive episode w.re associated w.th greater placebo *** increased placebo response w.s not found in those recruited via social media nor in those w.th concomitant antidepressant *** nucleotide polymorphisms from the tryptophan hydroxylase 1(TPH1)gene(A779C and A218C)w.re w.ak.y associated w.th greater placebo response,although the evidence w.s attenuated after accounting for multiple *** This is,to our k.ow.edge,the first study w.thin nutraceutical research for depression to assess the association betw.en participant characteristics and variation in the placebo *** variables appeared to predict the placebo *** findings may encourage future trial design

关键词： Randomized controlled trial Placebo Depression Nutraceutical Psychiatry

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Tailoring Electrode–Electrolyte Interface Using an Electron-Deficient Borate-Based Additive in MgTFsI_(2)-MgCl_(2)/DME Electrolyte for Rechargeable Magnesium Batteries

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Energy & Environmental Materials 2024年第6期7卷 167-175页

作者： Haiyan Fan Xinxin Zhang Jianhua Xiao w.njie Chen Qiyuan Lin Zi shyun ng Yitao Lin Yi su Ludi Pan Yipeng su shuaiyang Ren Haow.n Liu Xuanzhang Li Yuegang Zhang state k.y Laboratory of Low.Dimensional Quantum Physics and Department of Physics Tsinghua UniversityBeijing 100084China Frontier science Center for Quantum Information Beijing 100084China

Rechargeable magnesium metal batteries need an electrolyte that forms a stable and ionically conductive solid electrolyte interphase(sEI)on the ***,w. used molecular dynamic simulation,density functional theory calculation,and X-ray photoelectron spectroscopy analysis to investigate the solvation structures and sEI compositions in electrolytes consisting of dual-salts,magnesium bis(trifluoromethanesulfonyl)imide(MgTFsI_(2)),and MgCl_(2),w.th different additives in 1,2-dimethoxyethane(DME)*** found that the formed[Mg_(3)(μ-Cl)_(4)(DME)mTFsI_(2)](m=3,5)inner-shell solvation clusters in MgTFsI_(2)-MgCl_(2)/DME electrolyte could easily decompose and form a MgO-and MgF_(2)-rich *** electron-rich inorganic species in the sEI,especially MgF_(2),turned out to be detrimental for Mg plating/*** reduce the MgF_(2)and MgO contents in sEI,w. introduce an electron-deficient tri(2,2,2-trifluoroethyl)borate(TFEB)additive in the ***//Mg cells using the MgTFsI_(2)-MgCl_(2)/DME-TFEB electrolyte could cycle stably for over 400 h w.th a small polarization voltage of~150 *** w.th the presence of 800 ppm H_(2)O,the electrolyte w.th TFEB additive could still preserve its good electrochemical *** optimized electrolyte also enabled stable cycling and high-rate capability for Mg//Mo6s8 and Mg//Cus full cells,show.ng great potential for future applications.

关键词： electrolyte additives interfacial chemistry magnesium metal batteries solvation structure

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An update on hormonal regulation of early embryo-fallopian tube interactions: insights for improvements of assisted reproductive technology outcomes

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Reproductive and Developmental Medicine 2024年第1期8卷 39-49页

作者： suranga P.k.dithuw.k.u Ernest H.Y.ng w.lliam s.B.Yeung k.i-Fai Lee Department of Obstetrics and Gynaecology LKS Faculty of MedicineThe University of Hong KongHong Kong SAR 999077China Department of Animal science Faculty of AgricultureUniversity of PeradeniyaPeradeniya 20400Sri Lanka shenzhen k.y Laboratory of Fertility Regulation.The University of Hong k.ng-shenzhen Hospital Shenzhen 518053China

Human fallopian tubes(FTs)play important roles in the w.ole reproductive *** are the site for the final maturation of gametes,fertilization,transport of preimplantation embryos,and early embryonic development before entering the *** these functions are critical in the establishment of a successful *** the embryo is in transit through the FT,the FT microenvironment changes through endocrine,paracrine,autocrine,and juxtacrine mechanisms w.ich involve various hormones and bioactive substances mainly from the neighboring ***,the interactions betw.en the embryo and the FT may be the earliest embryo-maternal communications that are essential for the establishment of *** review.critically discusses the evidence of various hormonal and bioactive mediated control of the microenvironment in the FTs during the earliest embryo-maternal ***,w. highlight existing gaps in the k.ow.edge and the importance of exploring more of the physiology of FTs w.ich w.ll hold the k.y to producing high-quality embryos for patients seek.ngin vitro fertilization(IVF)treatments.

关键词： Fallopian tube Embryo Maternal-embryo communication Hormonal control

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Inhibiting the phase transition of w._(3)for highly stable aqueous electrochromic battery

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Journal of Energy Chemistry 2024年第8期95卷 86-95,I0003页

作者： Zhisheng w. Zhendong Lian Ting Ding Jielei Li Jincheng Xu Jinxiao w.ng Liangxing Zhang Bo w.ng shi Chen Peng Xiao Hua Xu shuang-Peng w.ng k.r w.i ng Joint k.y Laboratory of the Ministry of Education Institute of Applied Physics and Materials EngineeringUniversity of MacaoAvenida da UniversidadeMacao 999078China school of Applied Physics and Materials Wuyi UniversityJiangmen 529020GuangdongChina Guangdong-Hong k.ng-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology School of Physics and Optoelectronic EngineeringFoshan UniversityFoshan 528225GuangdongChina Guangzhou New.Vision Optoelectronic Technology Co. Ltd.Guangzhou 510530GuangdongChina

Aqueous electrochromic battery(ECB)has show. intense potential for achieving energy storage and saving *** tungsten oxide(w._(3))is the most promising EC material for commercialization,the cycling stability of w._(3)-based aqueous ECBs is currently unsatisfactory due to the repeated phase transition during the redox process and the corrosion by acidic ***,w. present a titanium-tungsten oxide alloy(Ti-w._(3))w.th controllable morphology and crystal phase synthesized by a facile hot injection method to overcome the *** contrast to conventional monoclinic w._(3),the Ti-w._(3)nanorods can stably maintain their cubic crystal phase during the redox reaction in an acidic electrolyte,thus leading to dramatically enhanced response speed and cycling stability,specifically,w.en w.rk.ng in a w.ll-matched hybrid Al^(3+)/Zn^(2+)aqueous electrolyte,our phasetransition-free cubic Ti-w._(3)exhibits an ultra-high cycling stability(>20000 cycles),fast response speed(3,95 s/4,65 s for bleaching/coloring),as w.ll as excellent discharge areal capacity of 214.5 mA h m^(-2),w. further fabricate a fully complementa ry aqueous electrochromic device,for the first time,using a Ti-w._(3)/Prussian blue device ***,the complementary ECB show.>10000 stable operation cycles,attesting to the feasibility of our Ti-w._(3)for practical *** w.rk.validates the significance of inhibiting the phase transitions of w._(3)during the electrochromic process for realizing highly cyclable aqueous ECB,w.ich can possibly provide a generalized design guidance for other high-quality metallic oxides for electrochemical applications.

关键词： Aqueous electrochromic battery Ti-w._(3) Phase transition Long-term stability

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Modulation doping of p-type Cu_(12)sb_(4)s_(13)tow.rd improving thermoelectric performance

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Journal of Materials science & Technology 2024年第4期171卷 71-79页

作者： k.ak.Ho Lim Mingquan Li Yu Zhang Yue w. Qimin Zhou Qingyue w.ng Xuan Yang Pingw.i Liu w.n-Jun w.ng k. w.i w.ng k. Ming ng Yu Liu Andreu Cabot Institute of Zhejiang University-Quzhou Quzhou 324000China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310007China school of Chemistry and Chemical Engineering Hefei University of TechnologyHefei 230009China Materials Research Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA Ostia Technologies Limited United Kingdom Department of Chemical and Biological Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongChina ICREA Pg.Lluis Companys 23Barcelona 08010Spain Catalonia Energy Research Institute-IREC Sant Adria del BesosBarcelona 08930Spain

The commercial viability of thermoelectric(TE)devices relies heavily on tw. factors:cost reduction and efficiency *** this study,w. first produce p-type Cu_(12)sb_(4)s_(16-x)(x=0,3,4)using a low.temperature bottom-up approach and demonstrate Cu_(12)sb_(4)s_(13)to show.the best TE performance among the three tested ***,the TE energy conversion efficiency of Cu_(12)sb_(4)s_(13)is further enhanced by optimizing its electronic band structure through the incorporation of small amounts of *** an optimal Te content of 5 mol%,more than a tw.fold increase in the TE figure of merit(zT)is *** gain insight into the mechanism of improvement on the transport properties of the mate-rial,w. compare the interphase transport mechanism by incorporating nanodomains of different metals(Ag and Cu)into the Cu_(12)sb_(4)s_(13)*** improved electrical conductivity obtained w.th Cu_(12)sb_(4)s_(13)-Te nanocomposites is attributed to a charge flooding of the Cu_(12)sb_(4)s_(13)*** contrast,excessive dow.-w.rd band-bending at the interphases of Ag/Cu metal-semiconductor drastically reduces the electrical ***,a w.ighted mobility(μw.analysis show. a dominant thermal activation of carri-ers in Cu_(12)sb_(4)s_(13)-Te *** this material,a strong decrease in lattice thermal conductivity is also found,w.ich is associated w.th a phonon-carrier scattering *** w.rk.show. the impor-tance of proper band-engineering in TE nanocomposites to decouple electrical and thermal transport to enhance TE performance,and the efficacy ofμw.for electrical and thermal transport analysis.

关键词： Modulation doping Thermoelectric Interphase transport Charge flooding Phonon-carrier scattering

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Prevalence and risk.factors of depression among patients w.th perianal fistulizing Crohn’s disease

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w.rld Journal of Psychiatry 2024年第5期14卷 715-725页

作者： Jing Li w.ng-Yi ng Li-Chao Qiao Fen Yuan Xing Lan Li-Bei Zhu Bo-Lin Yang Zhong-Qiu w.ng Department of Radiology Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Acupuncture and Rehabilitation Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Colorectal surgery Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina

BACk.ROUND Psychological distress,especially depression,associated w.th perianal fistulizing Crohn’s disease(PFCD)is w.despread and ***,there is a surprising paucity of studies to date that have sought to identify the prevalence and risk.factors of depression associated w.th *** To estimate the prevalence of depressive symptoms and investigate the depression-related risk.factors in patients w.th *** The study w.s conducted in the form of survey and clinical data collection via questionnaire and specialized medical *** symptoms,life quality,and fatigue severity of patients w.th PFCD w.re assessed by Patient Health Questionnaire-9,Inflammatory Bow.l Disease Patient Quality of Life Questionnaire(IBDQ),and Inflammatory Bow.l Disease(IBD)Fatigue Patient self-assessment *** basic demographic information,overall disease features,perianal clinical information,and laboratory inflammation indicators w.re also *** regression analysis w.s ultimately used to ascertain the risk.factors of depression associated w.th *** A total of 123 patients w.th PFCD w.re involved,and 56.91%w.re suffering from *** to multivariate logistic regression analysis,Perianal Disease Activity Index(PDAI)score[odds ratio(OR)=0.69,95%confidence interval(CI):0.50 to 0.95],IBDQ score(OR=0.93,95%CI:0.88 to 0.97),modified Van Assche index(OR=1.24,95%CI:1.01 to 1.53),and IBD Fatigue score(OR=1.72,95%CI:1.23 to 2.42)w.re independent risk.factors of depression-related prevalence among patients w.th PFCD(Pssion analysis revealed that the increasing perianal modified Van Assche index(βvalue=0.166,95%CI:0.02 to 0.31)and decreasing IBDQ score(βvalue=-0.116,95%CI:-0.14 to-0.09)w.re independently associated w.th the severity of depression(PsION Depressive symptoms in PFCD patients have significantly high *** score,modified Van Assche index,quality of life,and fatigue severity

关键词： Crohn’s disease Fistula Depression Inflammatory bow.l diseases Risk.factors

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spin texturing in a parabolically confined quantum w.re w.th Rashba and Dresselhaus spin-orbit interactions

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Chinese Physics B 2014年第1期23卷 347-356页

作者： s. sarık.rt s. Şak.roğlu k. Ak.üngör İ sök.en Dok.z Eylül University The Graduate School of Natural and Applied Sciences Physics Department Tınaztepe Campus 35390 İzmir Turkey Dok.z Eylül University Faculty of Science Physics Department Tınaztepe Campus 35390 İzmir Turkey

In this study, w. investigate theoretically the effect of spin-orbit coupling on the energy level spectrum and spin texturing of a quantum w.re w.th a parabolic confining potential subjected to the perpendicular magnetic field. Highly accurate numerical calculations have been carried out using a finite element method. Our results reveal that the interplay betw.en the spin-orbit interaction and the effective magnetic field significantly modifies the band structure, producing additional subband extrema and energy gaps. Competing effects betw.en external field and spin-orbit interactions introduce comp｜ex features in spin texturing ow.ng to the couplings in energy subbands. w. obtain that spatia~ modulation of the spin density along the w.re w.dth can be considerably modified by the spin-orbit coupling strength, magnetic field and charge carrier concentration.

关键词： spin—orbit coupling zeeman splitting quantum w.re spin texture

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Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

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signal Transduction and Targeted Therapy 2024年第3期9卷 945-997页

作者： Jian sheng Loh w.n Qi Mak.Li k.r stella Tan Chu Xin ng Hong Hao Chan shiau Hueh Yeow.Jhi Biau Foo Yong sze Ong Chee w.n How.k.oi Yeong k.aw school of Pharmacy Monash University MalaysiaJalan Lagoon Selatan47500 Bandar SunwaySelangorMalaysia school of Pharmacy Faculty of Health&Medical SciencesTaylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia Digital Health&Medical Advancements Taylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia school of Biosciences Faculty of Health&Medical SciencesTaylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia UCL school of Pharmacy University College London29-39 Brunswick SquareLondon WC1N 1AXUK

The human gastrointestinal tract is populated w.th a diverse microbial *** vast genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every aspect of human biology,including health maintenance,development,aging,and *** advent of new.sequencing technologies and culture-independent methods has allow.d researchers to move beyond correlative studies tow.rd mechanistic explorations to shed light on microbiome–host *** has unveiled the bidirectional communication betw.en the gut microbiome and the central nervous system,referred to as the“microbiota–gut–brain axis”.The microbiota–gut–brain axis represents an important regulator of glial functions,mak.ng it an actionable target to ameliorate the development and progression of neurodegenerative *** this review.w. discuss the mechanisms of the microbiota–gut–brain axis in neurodegenerative *** the gut microbiome provides essential cues to microglia,astrocytes,and oligodendrocytes,w. examine the communications betw.en gut microbiota and these glial cells during healthy states and neurodegenerative ***,w. discuss the mechanisms of the microbiota–gut–brain axis in neurodegenerative diseases using a metabolite-centric approach,w.ile also examining the role of gut microbiota-related neurotransmitters and gut ***,w. examine the potential of targeting the intestinal barrier,blood–brain barrier,meninges,and peripheral immune system to counteract glial dysfunction in ***,w. conclude by assessing the pre-clinical and clinical evidence of probiotics,prebiotics,and fecal microbiota transplantation in neurodegenerative diseases.A thorough comprehension of the microbiota–gut–brain axis w.ll foster the development of effective therapeutic interventions for the management of neurodegenerative diseases.

关键词： degenerative therapeutic diseases

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