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Energy & Environmental Materials 2024年第1期7卷 147-152页

作者： sun Kyung Hwang ik Jae Park se Won seo Jae Hyun Park so Jeong Park Jin Young Kim Department of Materials science and Engineering Seoul National UniversitySeoul 08826Korea Department of Applied Physics Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials and systems Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials(RIAM) Seoul National UniversitySeoul 08826Korea

In spite of the high potential economic feasibility of the tandem solar cells consisting of the halide perovskite and the kesterite Cu2Znsn(s,se)4(CZTsse),they have rarely been demonstrated due to the difficulty in implementing solution-processed perovskite top cell on the rough surface of the bottom ***,we firstly demonstrate an efficient monolithic two-terminal perovskite/CZTsse tandem solar cell by significantly reducing the surface roughness of the electrochemically deposited CZTsse bottom *** surface roughness(R_(rms))of the CZTsse thin film could be reduced from 424 to 86 nm by using the potentiostatic mode rather than using the conventional galvanostatic mode,which can be further reduced to 22 nm after the subsequent ion-milling *** perovskite top cell with a bandgap of 1.65 eV could be prepared using a solution process on the flattened CZTsse bottom cell,resulting in the efficient perovskite/CZTsse tandem solar *** the current matching between two subcells involving the thickness control of the perovskite layer,the best performing tandem device exhibited a high conversion efficiency of 17.5%without the hysteresis effect.

关键词： CZTsse monolithic tandem solar cells perovskite solution process surface roughness control

Acute cholangitis with Achromobacter xylosoxidans bacteremia after endoscopic retrograde cholangiopancreatography in hilar cholangiocarcinoma:A case report

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World Journal of Clinical Cases 2024年第20期12卷 4377-4383页

作者： ik Hyun Jo sung Woo Ko Department of Internal Medicine St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 16471South Korea Department of Internal Medicine Eunpyeong St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 03312South Korea

BACKGROUND Achromobacter xylosoxidans is a Gram-negative opportunistic aerobe,usually causing nosocomial infections in immunocompromised patients with manifestations including bacteremia,pneumonia,and catheter-related ***,*** have not yet been reported to cause biliary system *** sUMMARY A 72-year-old woman presented to the outpatient department of our hospital with a chief complaint of *** tomography of her abdomen revealed the presence of a mass of approximately 2.4 cm in the hilar portion of the common hepatic duct,consistent with hilar *** performed endoscopic retrograde cholangiopancreatography(ERCP)to decompress the obstructed left and right intrahepatic ducts(IHDs)and placed 10 cm and 11 cm biliary stents in the left and right IHDs,***,the day after the procedure,the patient developed post-ERCP cholangitis as the length of the right IHD stent was insufficient for proper bile *** blood culture of the patient tested positive for *** measures included the replacement of the right IHD stent(11 cm)with a longer one(12 cm)and administering culturedirected antibiotic therapy,solving the cholangitis-related *** the cholangitis had resolved,the patient underwent surgery for hilar cholangiocarcinoma and survived for 912 d without *** ***-induced biliary system infections are extremely *** awareness of physicians and endoscopists is required as this rare pathogen might cause infection after endoscopic procedures.

关键词： Achromobacter xylosoxidans Bacteremia Cholangitis Endoscopic retrograde cholangiopancreatography Malignant biliary stricture Cholangiocarcinoma Case report

Galectin 3-binding protein(LGALs3BP)depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1(TGF-β1)availability and inhibits hepatocarcinogenesis

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Cancer Communications 2024年第10期44卷 1106-1129页

作者： Dae-Hwan Kim Minjeong sung Myong-suk Park Eun-Gene sun sumin Yoon Kyung Hyun Yoo Kamalakannan Radhakrishnan sung Yun Jung Woo-Kyun Bae sang-Hee Cho ik-Joo Chung Department of Internal Medicine Division of Hematology and OncologyChonnam National University Medical SchoolHwasunSouth Korea Department of Internal Medicine Division of Hematology and OncologyChonnam National University Hwasun HospitalHwasunSouth Korea Combinatorial Tumor Immunotherapy MRC Center Chonnam National University Medical SchoolHwasunSouth Korea National Immunotherapy Innovation Center HwasunSouth Korea BioMedical sciences Graduate Program Chonnam National UniversityHwasunSouth Korea Department of Biological science SookmyungWomen’s UniversitySeoulSouth Korea Clinical Vaccine R&D Center Chonnam National UniversityHwasunSouth Korea Department of Biochemistry and Molecular Pharmacology Baylor College of MedicineHoustonTexasUSA

Background:Increased Galectin 3-binding protein(LGALs3BP)serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma(HCC).Considering the crucial role of transforming growth factor-β1(TGF-β1)in the emergence of these diseases,the present study tested the hypothesis that LGALs3BP regulates the TGF-β1 signaling ***:The expression levels of LGALs3BP and TGFB1 were analyzed in patients with metabolic dysfunction-associated steatohepatitis(MAsH)and *** omics techniques,such as RNA-sequencing,transposaseaccessible chromatin-sequencing assay,and liquid chromatography-tandem mass spectrometry proteomics,were used to identify the regulatory mechanisms for the LGALs3BP-TGF-β1 *** effects of altered TGF-β1 signaling by LGALs3BP were investigated in conditional LGALs3BP-knockin and LGALs3BP-knockout ***:In patients with MAsH and HCC,the levels of LGALs3BP and TGFB1 exhibited positive *** of LGALs3BP by the inflammatory cytokine interferonαin HCC cells or ectopic overexpression of LGALs3BP in hepatocytes promoted the expression levels of *** fibrosis was observed in the livers of hepatocyte-specific LGALs3BP-knockin mice,with increased TGFB1 ***3BP directly bound to and assembled integrinαV,an integral mediator required for releasing active TGF-β1 from extracellular latent complex with the rearranged F-actin *** released TGF-β1 activated JunB transcription factor,which in turn promoted the TGF-β1 positive feedback ***3BP deletion in the hepatocytes downregulated TGF-β1 signaling and CCl4 induced ***,LGALs3BP depletion hindered hepatocarcinogenesis by limiting the availability of fibrogenic TGF-β***:LGALs3BP plays a crucial role in hepatic fibrosis and carcinogenesis by controlling the TGF-β1 signaling pathway,making it a promising therapeutic target in TGF-β1-related diseases.

关键词： F-actin FAK hepatic carcinogenesis IntegrinαV Interferonα JunB LGALs3BP metabolic dysfuntion-associated steatohepatitis tensile force TGF-β1

THE PICARD THEOREM ON s-METRIC sPACEs

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Acta Mathematica scientia 2018年第4期38卷 1245-1258页

作者： Nihal Yihnaz OZGUR Nihal tas Department of Mathematics Balikesir University 10145 Balikesir Turkey

Recently, the notion of an s-metric space is defined and extensively studied as a generalization of a metric space. In this paper, we define the notion of the s∞-space and prove its completeness. We obtain a new gene... 详细信息

关键词： s∞-space completeness Picard Theorem initial value problem

Mapping the risk of winter storm damage using GIs-based fuzzy logic

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Journal of Forestry Research 2020年第3期31卷 729-742页

作者： Abdullah E.Akay Inanc tas Department of Forest Engineering Faculty of Forestry16310 YildirimBursaTurkey

Abiotic and biotic factors that cause damage to forest trees also threaten the sustainability of forest *** winter storms can be one of the most damaging forces,very few studies have focused on winter storm damage in *** prevent or minimize storm damage,we must evaluate the factors that influence the degree of damage and develop storm risk maps for the forested ***,a GIs-based mathematical model(fuzzy logic)was used to develop such a risk map by considering risk factors such as tree species,tree age,crown density,site quality,topographical features(elevation,slope,aspect),climatic variables(wind,precipitation),and soil *** Alabarda Forest Enterprise Chief within the borders of Tavs?anl?Forest Enterprise Directorate was selected as the study area due to high occurrence of storm damage in the region during winter 2015–*** model verification,the risk map of storm damage was compared to the actual areal distribution of storm damage reported by the Enterprise *** model based on fuzzy logic indicated that slightly more than half of the study area(52.49%)was under very low storm damage risk,28.12%was under low risk and 19.19%was classified as high risk.A very small portion of the total study area was classified as very high *** results indicated a close relation with the storm damage map generated using Tavsanl?FED *** results revealed that the most effective risk predictors for overall storm damage risk were wind direction and speed,followed by slope and site quality factors.

关键词： Fuzzy logic GIs Risk map storm damage

Does acupuncture have a positive effect on school success in children?

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Journal of Traditional Chinese Medicine 2014年第4期34卷 450-454页

作者： Demet tas Hakan Volkan ACAR Department of Pediatrics Ulus State HospitalAnkara 06030Turkey Department of Anesthesiology and Intensive Care Ankara Training and Research Hospital of Ministry of HealthAnkara 06340Turkey

OBJECTIVE:To evaluate school success in pediatric patients undergoing acupuncture treatment for ***: The grades achieved during both school terms by children undergoing acupuncture treatment for various indications at the pediatric out patient clinic of Ulus state Hospital were analyzed. Exam grades in mathematics, social studies,and Turkish was compared between the first and the second terms. Forty children were included in thestudy,with 22 male and 18 female,and their average age was 11.1 years. These patients were undergoing acupuncture treatment for attention deficit-hyperactivity disorder(ADHD), enuresis nocturna, migraine, obesity, atopic dermatitis, alopecia areata, and Tourette's syndrome. Treatments were done at the beginning of the second term. Four of the 25 patients with ADHD had borderline intelligence *** report cards of all 40 patients were examined, and their grades in the first and these condschool term were ***: There was a statistically significant increase in the grades obtained in mathematics, social studies, and Turkish(Pstudents from the first to the second school term. When 4 ADHD patients with borderline deficiency in intelligence were excluded, and the grades among the 21 patients with ADHD were compared for both terms, there was also a statistically significant increase in mathematics, social studies, and Turkish grades(PsION: Acupuncture contributed to the academic success of the children who under went acupuncture treatment for their primary symptoms.

关键词： Acupuncture Child Learning Attention deficit disorder with hyperactivity

Left-sided appendicitis:Review of 95 published cases and a case report

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World Journal of Gastroenterology 2010年第44期16卷 5598-5602页

作者： sami Akbulut Abdullah Ulku Ayhan senol Mahmut tas Yusuf Yagmur Department of surgery Diyarbakir Education and Research Hospital Department of Radiology Diyarbakir Education and Research Hospital Department of Emergency Medicine Diyarbakir Education and Research Hospital

AIM:To give an overview of the literature on left-sided acute appendicitis (LsAA) associated with situs inversus totalis (sIT) and midgut malrotation (MM).METHODs:We present a new case of LsAA with sIT and a literature review of studies published in the English language on LsAA,accessed via PubMed and Google scholar ***:Ninety-five published cases of LsAA were evaluated and a 25-year-old female,who presented to our clinic with left lower abdominal pain caused by LsAA,is *** the reviewed literature,fiftyseven patients were male and 38 were female with an age range of 8 to 82 years and a median age of 29.1 ± 15.9 ***-six patients had sIT,23 had MM,three had cecal malrotation,and two had a previously unnoted congenital ***-nine patients had presentedto the hospital with left lower,14 with right lower and seven with bilateral lower quadrant pain,and seven subjects complained of left upper quadrant *** diagnosis was established preoperatively in 49 patients,intraoperatively in 19,and during the postoperative period in five;14 patients were aware of having this *** data of eight patients were not *** patients underwent laparoscopic appendectomy,which was combined with cholecystectomy in two *** examination of the appendix specimens revealed adenocarcinoma in only two of 95 ***:The diagnosis of left lower quadrant pain is based on well-established clinical symptoms,physical examination and physician's experience.

关键词： Diagnostic dilemma Left lower quadrant pain Left-sided appendicitis Midgut malrotation situs inversus totalis

A taxonomic review of the genus Miaenia Pascoe, 1864(Coleoptera: Cerambycidae) from south Korea with a new record of M. tonsa(Bates)

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Journal of Forestry Research 2018年第3期29卷 822-829页

作者： ik Je Choi Tae sung Kwon Jongok Lim silkworm and Insect Management Center Gyeongsangbuk-do Agricultural Resource Management Institute Forest Insect Pests and Disease Division Korea Forest Research Institute Division of Forest Biodiversity Korea National Arboretum

The cerambycid genus Miaenia Pascoe(Coleoptera: Cerambycoidea) of south Korea is taxonomically reviewed. Two species, Miaenia fasciata fasciata(Matsushita) and Miaenia maritima Tsherepanov have been recorded. In this paper, M. tonsa(Bates) is added to the Korean cerambycid fauna for the first time. A key to Korean Miaenia species, re-description and diagnostic illustrations, including male genitalia for each species, are provided.

关键词： Acanthocinini Cerambycidae Miaenia New species south Korea Taxonomy

Dynamic genetic features of eukaryotic plankton diversity in the Nakdong River estuary of Korea

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Chinese Journal of Oceanology and Limnology 2017年第4期35卷 844-857页

作者： LEE Jee Eun CHUNG ik Kyo LEE sang-Rae Division of Earth Environmental system Oceanography Major Pusan National University Marine Research Institute Pusan National University

Estuaries are environments where freshwater and seawater mix and they display various salinity *** construction of river barrages and dams has rapidly changed these environments and has had a wide range of impacts on plankton *** understand the dynamics of such communities,researchers need accurate and rapid techniques for detecting plankton *** evaluated the diversity of eukaryotic plankton over a salinity gradient by applying a metagenomics tool at the Nakdong River estuary in *** samples were collected on three dates during summer and autumn of 2011 at the Eulsukdo Bridge at the mouth of that *** the 18 s rDNA allowed us to analyze 456 clones and 122 *** sequences revealed various taxonomic groups and cryptic genetic variations at the intra-and inter-specific *** analyzing the same station at each sampling date,we observed that the phylotypes presented a salinity-related pattern of diversity in *** variety of species within freshwater samples reflected the rapid environmental changes caused by freshwater *** phylotypes accounted for the highest proportion of overall diversity in the seawater *** diatoms and dinoflagellates were observed in the freshwater,brackish and seawater *** biological data for species composition demonstrate the transitional state between freshwater and ***,this metagenomics information can serve as a biological indicator for tracking changes in aquatic environments.

关键词： 18s rDNA clone library metagenome estuary salinity gradient

Alteration of the p53 gene during tree shrews' hepatocarcinogenesis

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Hepatobiliary & Pancreatic Diseases International 2003年第4期2卷 612-616页

作者： Young ik Lee Bioscience Research Division Korea Research Institute of Bioscience and Biotechnology P. O. Box 115 Yusong Taejon 305-600 South Korea

OBJECTIVE: To detect the expression and variation of the p53 gene in hepatocarcinogenesis of tree shrews induced by hepatitis B virus (HBV) and aflatoxin B_1(AFB_1). METHODs: Tree shrews were divided into four groups: group A, infected with HBV and fed with AFB_1; group B, only infected with HBV; group C, fed with AFB_1 alone; and group D normal control. The tree shrews underwent liver biopsy every. 15 weeks. Liver and tumor tissues were detected by immunohistochemistry and molecular biotechnologies. REsULTs: The incidence of hepatocellular carcinoma (HCC) was higher in group A (66.7%) than in groups B (0) and C (30%). HCC occurrence was earlier in group A than in group C (120.0±16.6 wk vs 153.3±5.8 wk, t=3.336, Ps not found in all groups before 75 weeks of experiment. At the 105th week, the expression rates of mutated p53 protein were 78.6%, 60.0% and 71.4% in groups A, B and C respectively, which were significantly higher than that in group D (10%) (X^2≥5.03, Ps detected in groups A and C. The mutational points of the p53 gene in liver cancer of tree shrews were at codon 275, 78 and 13. Nucleotide sequence and amino acids sequence of tree shrew's wild-type p53 were 91.7% and 93.4% in homology, compared with those of human p53, respectively. CONCLUsIONs: Remarkable synergistic effect on HCC exists between HBV and AFB_1. Mutated p53 protein expressed before occurrence of HCC promotes the development of HCC. HBV and AFB_1 may synergistically induce p53 gene mutation.

关键词： hepatocellular carcinom gene p53 hepatitis B virus aflatoxin B_1 tree shrew