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Adenylate kinase phosphate energy shuttle underlies energetic communication in flagellar axonemes

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science China(Life sciences) 2024年第8期67卷 1697-1714页

作者： Huan Wu Yanman zha.g Yuqian Li shuya sun Jintao zha.g Qingsong Xie Yue Dong shushu Zhou Xuan sha Kuokuo Li Jinyi Chen Xin zha.g Yang gao Qunshan shen guanxiong Wang Xiaomin zha Zongliu Duan Dongdong Tang Chuan Xu Hao geng Mingrong Lv Yuping Xu Ping Zhou zhaolian Wei Rong Hua Yunxia Cao Mingxi Liu Xiaojin He Reproductive Medicine Center Department of Obstetrics and GynecologyThe First Affiliated Hospital of Anhui Medical UniversityHefei 230022China state Key Laboratory of Reproductive Medicine and Offspring Health Department of Histology and EmbryologySchool of Basic Medical SciencesNanjing Medical UniversityNanjing 210029China state Key Laboratory of Reproductive Medicine and Offspring Health The Affiliated Taizhou People’s Hospital of Nanjing Medical UniversityTaizhou School of Clinical MedicineNanjing Medical UniversityNanjing 211166China Reproductive Medicine Center Department of Obstetrics and GynecologyShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China state Key Laboratory of Reproductive Medicine and Offspring Health Clinical Center of Reproductive MedicineThe First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China NHC Key Laboratory of study on Abnormal gametes and Reproductive Tract(Anhui Medical University) Hefei 230032China Key Laboratory of Population Health Across Life Cycle(Anhui Medical University) Ministry of Education of the People’s Republic of ChinaHefei 230032China Anhui Province Key Laboratory of Reproductive Health and genetics Hefei 230032China Biopreservation and Artificial Organs Anhui Provincial Engineering Research CenterAnhui Medical UniversityHefei 230032China

The complexities of energy transfer mechanisms in the flagella of mammalian sperm flagella have been intensively investigated and demonstrate significant diversity across *** shuttles,particularly adenylate kinase(AK)and creatine kinase(CK),are pivotal in the efficient transfer of intracellular ATP,showing distinct tissue-and ***,the expression profiles of AK and CK were investigated in mice and found to fall into four subgroups,of which subgroup III AKs were observed to be unique to the male reproductive system and conserved across *** AK8 and AK9 were found to be indispensable to male reproduction after analysis of an infertile male *** mouse models showed that AK8 and AK9 were central to promoting sperm *** combined with mass spectrometry revealed that AK8 and AK9 interact with the radial spoke(Rs)of the *** of various human and mouse sperm samples with substructural damage,including the presence of multiple Rs subunits,showed that the head of radial spoke 3 acts as an adapter for AK9 in the flagellar *** an ATP probe together with metabolomic analysis,it was found that AK8 and AK9 cooperatively regulated ATP transfer in the axoneme,and were concentrated at sites associated with energy consumption in the *** findings indicate a novel function for Rs beyond its structural role,namely,the regulation of ATP *** conclusion,the results expand the functional spectrum of AK proteins and suggest a fresh model regarding ATP transfer within mammalian flagella.

关键词： adenylate kinase subgroup III AKs AK8 AK9 male infertility ATP transfer radial spoke

单、双侧穿刺经皮椎体后凸成形术治疗老年骨质疏松性椎体压缩骨折的疗效比较

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临床骨科杂志 2024年第2期27卷 153-157页

作者：江帅查正查兴胜安徽医科大学附属安庆第一人民医院骨二科安徽安庆246003

目的比较单、双侧穿刺经皮椎体后凸成形术(PKP)治疗老年骨质疏松性椎体压缩骨折的疗效。方法将62例行PKP治疗的老年骨质疏松性椎体压缩骨折患者按单、双侧穿刺不同分为单侧组(32例)和双侧组(30例)。比较两组骨水泥注入量及渗漏情况、术... 详细信息

目的比较单、双侧穿刺经皮椎体后凸成形术(PKP)治疗老年骨质疏松性椎体压缩骨折的疗效。方法将62例行PKP治疗的老年骨质疏松性椎体压缩骨折患者按单、双侧穿刺不同分为单侧组(32例)和双侧组(30例)。比较两组骨水泥注入量及渗漏情况、术中X线透视时间、手术时间、术后疼痛VAs评分以及影像学指标。结果患者均获得随访,时间6~13个月。骨水泥注入量、术中X线透视时间、手术时间单侧组均少(短)于双侧组(Ps评分两组比较差异无统计学意义(P>0.05)。单侧组3例、双侧组7例发生骨水泥渗漏,但均无临床症状。伤椎前缘高度、伤椎中央高度、Cobb角两组术后均较术前改善(P0.05)。结论单、双侧穿刺PKP治疗老年骨质疏松性椎体压缩骨折均能改善患者疼痛症状、纠正脊柱后凸畸形,恢复伤椎高度,单侧穿刺术中X线透视时间和手术时间更短、骨水泥注入量更少。

关键词：单侧穿刺经皮椎体后凸成形术双侧穿刺经皮椎体后凸成形术脊柱胸腰段骨质疏松性椎体压缩骨折

高校图书馆员数据素养培育实践及启示——基于国外案例调查

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图书情报工作 2024年第7期68卷 46-56页

作者：罗靖琳刘倩秀查颖钟庆虹深圳大学图书馆深圳518061

[目的/意义]数据素养是高校图书馆员当前应必备的专业核心能力,国内外都在持续探索适合的馆员数据素养培育路径。我国在此方面尚处于起步阶段,调查和研究国外开展的高校图书馆员数据素养培育实践案例,归纳经验启示,有利于为我国馆员数... 详细信息

[目的/意义]数据素养是高校图书馆员当前应必备的专业核心能力,国内外都在持续探索适合的馆员数据素养培育路径。我国在此方面尚处于起步阶段,调查和研究国外开展的高校图书馆员数据素养培育实践案例,归纳经验启示,有利于为我国馆员数据素养培育提供借鉴,提升培育质量。[方法/过程]选取国外12个馆员数据素养培育案例,结合3P教育模型和传播学5W理论,从培育前提、过程、结果三个方面进行分析研究并总结启示。[结果/结论]构建普适性的馆员数据素养培育模型,基于此提出思考,从培育主体、对象、内容、方式、结果等方面提出具体建议。

关键词：数据素养高校图书馆员培育模型

FVIT-YOLO v8:基于多尺度融合注意机制的改进YOLO v8小目标检测

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红外技术 2024年第8期46卷 912-922页

作者：刘富宽罗素云何佳查超能上海工程技术大学机械与汽车工程学院上海201620

本文研究了遥感与无人机航拍图像中的小目标检测问题。由于这类图像存在目标尺度小、目标分布密集、背景复杂等特点,使得特征提取困难。目前针对小目标检测的算法,为了提升精度,大多忽略了参数量与推理速度的影响,这使得算法缺乏实用性... 详细信息

本文研究了遥感与无人机航拍图像中的小目标检测问题。由于这类图像存在目标尺度小、目标分布密集、背景复杂等特点,使得特征提取困难。目前针对小目标检测的算法,为了提升精度,大多忽略了参数量与推理速度的影响,这使得算法缺乏实用性。针对上述问题,本文提出了一种基于轻量化的多尺度融合注意机制的改进YOLO v8小目标检测算法。算法首先在YOLO v8的FPN结构中加入F算子,设计了多尺度特征的加权融合;然后在网络预测层剔除了P4、P5预测层,加入P2层用于小目标的预测;最后对轻量化自注意力机制进行图像输入网格化分割整合改进,并用它替换了FPN中的C2f模块,使得算法具有更好的全局感知能力,并大幅降低了参数量。与YOLO v8s相比,本文算法在DOTA数据集上的mAP提升了4.4%,网络参数量下降了52%,FPs达到了46帧/s。在VisDrone数据集中,本算法在精度上提升了8.2%。

关键词： YOLO v8 小目标检测 Transformer 轻量化实时性

Correlations of baryon and charge stopping in heavy ion collisions

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Chinese Physics C 2024年第4期48卷 89-94页

作者：吕文棣李洋李子阳马荣荣唐泽波 Prithwish Tribedy Chun Yuen Tsang 许长补查王妹 state Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Physics Department Brookhaven National LaboratoryUptonNY 11973USA Department of Physics Kent State UniversityKentOH 44242USA

Baryon numbers are theorized to be carried by valence quarks in the standard QCD picture of the baryon *** theory proposed an alternative baryon number carrier,a non-perturbative Y-shaped configuration of the gluon field,called the baryon junction in the ***,neither of these theories has been verified ***,searching for the baryon junction by investigating the correlation of net-charge and net-baryon yields at midrapidity in heavy-ion collisions has been *** paper presents studies of such correlations in collisions of various heavy ions from oxygen to uranium with the UrQMD Monte Carlo *** UrQMD model implements valence quark transport as the primary means of charge and baryon stopping at *** studies are also conducted for isobaric ^(96)_(40)Zr+^(96)_(40)Zr and ^(96)_(44)Ru+^(96)_(44)Ru *** found a universal trend of charge stopping with respect to baryon stopping and discovered that the charge stopping is always greater than the baryon *** study provides a model baseline in valence quark transport for what is expected in net-charge and net-baryon yields at the midrapidity of relativistic heavy-ion collisions.

关键词： baryon junction baryon number carrier baryon stopping relativistic heavy ion collisions

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食品检测中标准化农药残留检测技术研究

中国标准化 2024年第8期 198-201页

作者：查勇姜琛日照市质量检验检测研究院日照市政务服务中心

农药残留引发的食品安全问题日益受到公众重视,建立科学合理的标准化农药残留检测技术,对保障食品安全意义重大。本文以分析当前农药残留问题现状入手,综述研究进展,介绍目前常见的农药残留检测技术,分析各技术特点、适用范围和优缺点,... 详细信息

农药残留引发的食品安全问题日益受到公众重视,建立科学合理的标准化农药残留检测技术,对保障食品安全意义重大。本文以分析当前农药残留问题现状入手,综述研究进展,介绍目前常见的农药残留检测技术,分析各技术特点、适用范围和优缺点,提出实现标准化农药残留检测的设想与创新策略,旨在为我国食品安全工作提供参考。

关键词：食品检测标准化农药残留检测

Crustal thickness and Poisson's ratio beneath the Yunnan region

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science China Earth sciences 2013年第3期56卷 693-702页

作者： zha XiaoHui LEI Jianshe Key Laboratory of Crustal Dynamics Institute of Crustal Dynamics China Earthquake Administration

A total of 1939 receiver functions were obtained from 732 teleseismic events （M〉5.0） recorded at 21 broadband portable seis- mic stations on the Tengchong, Baoshan and simao blocks and Yangtze platform. These stations were installed by the Institute of Crustal Dynamics, China Earthquake Administration during 2010 and 2011. Using the H-x stacking and searching method, crustal thickness and velocity ratio beneath the stations are obtained. Results show that crustal thickness and Poisson＇s ratio in- ferred from the velocity ratio clearly vary, and they illustrate block features in deep structures. Except for the Tengchong block crustal thickness increases from south to north along the same block and from west to east across different blocks. In the Yangtze platform, Poisson＇s ratio and crustal thickness show a consistent and significant increasing trend from south to north, possibly indicating that crustal thickening is caused mainly by lower crustal variations. In contrast, Poisson＇s ratio has no sig- nificant change within the Baoshan and simao blocks. such differences demonstrate that the Jinshajiang-Red River fault is a southern boundary of the south China block. The H-κ results inferred from three portable stations on the Tengchong block show high Poisson＇s ratios, but they vary clearly with back-azimuth, implying the existence of strong anisotropy in the crustal medium beneath the stations.

关键词： portable seismic observations receiver function crustal thickness Poisson's ratio Yunnan region

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CVD参数对镀镍碳纤维原位生长CNFs形貌的影响及生长机理分析

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化工新型材料 2024年第5期52卷 198-201,207页

作者：贾晓菁张璋查萌航空工业第一飞机设计研究院标准工艺材料研究所西安710089

碳纤维具有低密度、高模量及高力学强度等优势,是常见的复合材料增强体。通过表面改性的方式,实现碳纤维表面纳米碳材料的有效复合,可获得更优的材料性能。而目前常见的制备方法,可能存在催化剂引入过程损伤纤维、反应时间长等缺点。因... 详细信息

碳纤维具有低密度、高模量及高力学强度等优势,是常见的复合材料增强体。通过表面改性的方式,实现碳纤维表面纳米碳材料的有效复合,可获得更优的材料性能。而目前常见的制备方法,可能存在催化剂引入过程损伤纤维、反应时间长等缺点。因此,探索工业化大规模负载纳米尺度碳材料的制备工艺十分必要。采用商用镀镍碳纤维为原料,通过调节化学气相沉积法(CVD)参数,实现不同形貌碳纳米纤维(CNFs)在镀镍碳纤维表面的有效负载,通过sEM、EDs和TEM等表征方式,结合扩散理论和V-s-L模型,分析催化剂厚度对催化剂形态的影响及CVD参数对各形貌产物的影响机理。结果表明,当催化剂层较厚时,催化剂以连续的片状形态存在,主要控制因素为热失配而非表面张力。H_(2)比例较高时,反应以扩散为主导,形貌趋向于催化剂位于中间的粗大CNFs阵列;H2比例较低时,反应以催化为主导,形貌趋向于具有夹层的CNFs团簇。

关键词：化学气相沉积法碳纤维原位生长碳纳米纤维生长机理

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基于注意力头数和词性融合的藏文预训练模型

科学技术与工程 2024年第23期24卷 9957-9964页

作者：张英拥措斯曲卓嘎拉毛杰扎西永珍尼玛扎西西藏大学信息科学技术学院拉萨850000 西藏自治区藏文信息技术人工智能重点实验室拉萨850000 藏文信息技术教育部工程研究中心拉萨850000

为了更好地学习藏文语言特征以及探究藏文预训练语言模型的最佳注意力机制头数,将词性与藏文预训练模型相结合,并进行了对比实验确定最佳的注意力头数,旨在提高语言模型对藏文语言特征的理解以及下游任务的性能。实验结果表明,在多个分... 详细信息

为了更好地学习藏文语言特征以及探究藏文预训练语言模型的最佳注意力机制头数,将词性与藏文预训练模型相结合,并进行了对比实验确定最佳的注意力头数,旨在提高语言模型对藏文语言特征的理解以及下游任务的性能。实验结果表明,在多个分类任务中,注意力头数为12的预训练模型皆表现了良好的性能。此外,将词性融入预训练模型后,文本、标题和情感分类任务的模型F_(1)值分别提高了0.57%、0.92%和1.01%。实验结果证明融入词性特征后,模型可以更准确地理解藏文语言结构和语法规则,从而提高分类任务的准确率。

关键词：注意力机制词性预训练语言模型文本分类情感分类