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Long-term outcomes after endoscopic removal of malignant colorectal polyps:Results from a 10-year cohort

World Journal of Gastrointestinal Endoscopy 2024年第4期16卷 193-205页

作者： Anna Fábián Renáta Bor Béla Vasas Mónika szűcs Tibor Tóth Zsófia Bősze Kata Judit szántó Péter Bacsur Anita Bálint Bernadett Farkas Klaudia Farkas Ágnes Milassin Mariann Rutka tamás Resál tamás Molnár Zoltán szepes Department of Internal Medicine University of SzegedSzent-Györgyi Albert Medical SchoolSzeged 6725Hungary Department of Pathology University of SzegedSzent-Györgyi Albert Medical SchoolSzeged 6725Hungary Department of Medical Physics and Medical Informatics University of SzegedSzent-Györgyi Albert Medical SchoolSzeged 6720Hungary UsZ Translational Colorectal Research Group Hungarian Centre of Excellence for Molecular MedicineSzeged 6725Hungary

BACKGROUND Choosing an optimal post-polypectomy management strategy of malignant colorectal polyps is challenging,and evidence regarding a surveillance-only strategy is *** To evaluate long-term outcomes after endoscopic removal of malignant colorectal *** A single-center retrospective cohort study was conducted to evaluate outcomes after endoscopic removal of malignant colorectal polyps between 2010 and *** disease rate and nodal metastases after secondary surgery and local and distant recurrence rate for those with at least 1 year of follow-up were *** rates for categorical variables and means for continuous variables with 95%confidence intervals were calculated,and Fisher’s exact test and Mann-Whitney test were *** risk factors of adverse outcomes were REsULTs In total,135 lesions(mean size:22.1 mm;location:42%rectal)from 129 patients(mean age:67.7 years;56%male)were *** proportion of pedunculated and non-pedunculated lesions was similar,with en bloc resection in 82%and 47%of lesions,*** differentiation,distance from resection margins,depth of submucosal invasion,lymphovascular invasion,and budding were reported at 89.6%,45.2%,58.5%,31.9%,and 25.2%,*** tumor was found in 10 patients,and nodal metastasis was found in 4 of 41 patients who underwent secondary surgical *** analysis identified piecemeal resection as a risk factor for residual malignancy(odds ratio:1.74;P=0.042).At least 1 year of follow-up was available for 117 lesions from 111 patients(mean follow-up period:5.59 years).Overall,54%,30%,30%,11%,and 16%of patients presented at the 1-year,3-year,5-year,7-year,and 9-10-year surveillance *** outcomes occurred in 9.0%(local recurrence and dissemination in 4 patients and 9 patients,respectively),with no difference between patients undergoing secondary surgery and surveillance *** Reporting of histological featur

关键词： Malignant colorectal polyps T1 tumor Endoscopic removal Outcomes Long-term surveillance

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提质培优背景下农类高职院校“双师型”教师队伍建设路径研究

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创新创业理论研究与实践 2024年第13期7卷 140-142页

作者：他淑君郑芳福建农业职业技术学院福建福州350000

提升高职院校教师“双师”素质是职业教育“三教”改革攻坚的必然要求,也是职业教育提质培优行动计划实施的重要内容。农类高职院校是培养“三农”发展所需技术技能型人才的重要基地,“双师型”教师队伍建设是培养高素质技术技能型人才... 详细信息

提升高职院校教师“双师”素质是职业教育“三教”改革攻坚的必然要求,也是职业教育提质培优行动计划实施的重要内容。农类高职院校是培养“三农”发展所需技术技能型人才的重要基地,“双师型”教师队伍建设是培养高素质技术技能型人才的关键。该文挖掘提质培优行动计划赋予农类高职院校“双师型”教师能力的新内涵,分析农类高职院校“双师型”教师队伍建设面临的问题,从3个方面提出农类高职院校“双师型”教师队伍建设策略,为进一步推动新阶段农类高职院校“双师型”教师队伍建设提供一定借鉴。

关键词：提质培优农类高职院校 “双师型”教师能力内涵困境建设路径

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Unit-cell design for two-dimensional phase-field simulation of microstructure evolution in single-crystal Ni-based superalloys during solidification

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Progress in Natural science:Materials International 2017年第6期27卷 678-686页

作者： Dongjia Cao Na ta Lijun Zhang state Key Lab of Powder Metallurgy Central South University Interdisciplinary Centre for Advanced Materials simulation (ICAMs) Ruhr-University Bochum

Phase-field simulation serves as an effective tool for quantitative characterization of microstructure evolution in single-crystal Ni-based superalloys during solidification nowadays. The classic unit cell is either limited to γdendrites along crystal orientation or too ideal to cover complex morphologies for γ dendrites. An attempt to design the unit cell for two-dimensional(2-D) phase-field simulations of microstructure evolution in single-crystal Ni-based superalloys during solidification was thus performed by using the MICREss(MICRostructure Evolution simulation software) in the framework of the multi-phase-field(MPF) model,and demonstrated in a commercial TMs-113 superalloy. The coupling to CALPHAD(CALculation of PHAse Diagram) thermodynamic database was realized via the TQ interface and the experimental diffusion coefficients were utilized in the simulation. Firstly, the classic unit cell with a single γ dendrite along crystal orientation was employed for the phase-field simulation in order to reproduce the microstructure ***, such simple unit cell was extended into the cases with two other different crystal orientations, i.e., and . Thirdly, for crystal orientations, the effect of γ dendritic orientations and unit cell sizes on microstructure and microsegregation was comprehensively studied, from which a new unit cell with multiple γdendrites was proposed. The phase-field simulation with the newly proposed unit cell was further performed in the TMs-113 superalloy, and the microstructure features including the competitive growth of γ dendrites,microsegregation of different solutes and distribution of γ′ grains, can be nicely reproduced.

关键词： Ni-based superalloys solidification Microstructure Phase-field simulation Unit cell

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Effects of rhamnolipid biosurfactant JBR425 and synthetic surfactant surfynol465 on the peroxidase-catalyzed oxidation of 2-naphthol

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Journal of Environmental sciences 2013年第7期25卷 1431-1440页

作者： Ivanec-Goranina Rūta Kulys Juozas Department of Chemistry and Bioengineering Faculty of Fundamental Sciences Vilnius Gediminas Technical University Institute of Biochemistry Vilnius University

The kinetics of the recombinant Coprinus cinereus peroxidase-catalyzed2-naphthol oxidationwas investigated in the presence of rhamnolipid biosurfactant JBR425 and synthetic surfactant surfynol465 at pH 5.5 and25°C,with concentrations of （bio）surfactants both less than critical micelle concentrations （CMC） and larger than CMC. Itwas shown that monomers of JBR425 aswell as monomers of surfynol465 had an enhancing effect on the conversion of2-naphthol indose response manner anddid not influence the initial rate of 2-naphthol oxidation. The resultswere accounted by a scheme,which contains a stadium of enzyme inhibition by oligomeric2- naphthol oxidation products. The action of the biosurfactant＇s （or synthetic surfactant＇s） monomerswas explained by avoidance of the enzyme active center clothingwith oligomers. similar results havedemonstrated the potential of rhamnolipid biosurfactant JBR425due to its biodegradability. When biosurfactants＇ concentrations are larger than CMC, （bio）surfactants have an opposite effect on the oxidation of2-naphthol by peroxidase.

关键词： oxidation peroxidase biosurfactant critical micelle concentration

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以城市命名的大道规划设计分析——以揭阳大道为例

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交通工程 2024年第2期24卷 68-74页

作者：塔建胡劲松广州市交通规划研究院有限公司广州510030

“大道”是道路通名等级划分中的最高级别,以城市名称命名的“大道”是1座城市的代表路,具有唯一性.本文首先给出了“大道”的界定,提出城市大道是1座城市的名片,能加深人们的归属感与认同感,提高城市知名度,并应执行高标准规划设计要求... 详细信息

“大道”是道路通名等级划分中的最高级别,以城市名称命名的“大道”是1座城市的代表路,具有唯一性.本文首先给出了“大道”的界定,提出城市大道是1座城市的名片,能加深人们的归属感与认同感,提高城市知名度,并应执行高标准规划设计要求;以揭阳市揭阳大道为例,分析了其规划定位和交通功能定位;最后从交通提速、慢行提升、景观提质等方面提出揭阳大道精细化、人性化、品质化设计方案.相关分析及设计理念可供类似项目参考借鉴.

关键词：道路命名大道揭阳大道定位规划设计

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反刍动物益生菌制剂的研究进展

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饲料工业 2024年第17期45卷 18-23页

作者：余小红刘晗璐赵德辉塔娜中国农业科学院草原研究所内蒙古呼和浩特010010 河北科技师范学院动物科技学院河北省特色动物种质资源挖掘与创新重点实验室河北秦皇岛066004 赤峰学院农学院蒙东农业生态保护与动植物资源开发利用实验室内蒙古赤峰024000 南京农业大学动物科技学院消化道微生物研究室江苏南京210095

一直以来,人们认为反刍动物因其强大的瘤胃发酵系统,对外源微生物具有较强的缓冲作用。但随着微生物学技术的发展,越来越多的研究证明外源添加益生菌制剂可调节微生物群落组成,维护瘤胃微环境动态平衡,影响挥发性脂肪酸的产生和氮的流动... 详细信息

一直以来,人们认为反刍动物因其强大的瘤胃发酵系统,对外源微生物具有较强的缓冲作用。但随着微生物学技术的发展,越来越多的研究证明外源添加益生菌制剂可调节微生物群落组成,维护瘤胃微环境动态平衡,影响挥发性脂肪酸的产生和氮的流动,促进饲料的消化利用,最终提高反刍动物生产性能,目前反刍动物生产中益生菌制剂的应用也日益广泛。此外,益生菌还可以减轻宿主动物应激反应、增强机体抗氧化能力,从而对反刍动物的生产性能以及生物习性产生影响。文章综述了益生菌影响反刍动物生产性能的各种直接和间接因素,为益生菌在反刍动物生产领域的应用提供参考。

关键词：益生菌反刍动物饲料添加剂瘤胃微生物消化

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脉冲多普勒雷达重频参数的一种序贯估计方法

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现代雷达 2024年第2期46卷 103-111页

作者：尚文秀袁硕拓世英刘章孟国防科技大学电子科学学院湖南长沙410073

针对逐脉冲序贯重频参数估计的场景,引入了评估变量控制对脉冲的缓存,对受漏脉冲和干扰脉冲等数据噪声污染的脉冲列进行了较高精度的参数估计;进一步对缓存区间内的脉冲采用试探整除的方法,对脉冲多普勒雷达截获脉冲列中重频切换的跳变... 详细信息

针对逐脉冲序贯重频参数估计的场景,引入了评估变量控制对脉冲的缓存,对受漏脉冲和干扰脉冲等数据噪声污染的脉冲列进行了较高精度的参数估计;进一步对缓存区间内的脉冲采用试探整除的方法,对脉冲多普勒雷达截获脉冲列中重频切换的跳变时刻进行了跟踪检测。仿真实验验证了文中所提的重频参数序贯估计方法相较于传统重频参数估计方法在序贯估计场景下的有效性和优越性。

关键词：脉冲多普勒雷达重频参数估计序贯估计

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基于超声-光声多模态成像仪器的骨结构及成分高分辨率表征方法

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仪器仪表学报 2024年第6期45卷 177-187页

作者：谢强李博艺杨春山韩帅他得安复旦大学信息科学与工程学院上海200433 复旦大学工程与应用技术研究院生物医学工程技术研究所上海200433

早期诊断和治疗骨质疏松症能显著降低骨折风险。骨组织物理结构和生化成分的影像学检查对骨质疏松症的诊断具有重要意义。为了克服基于射线的骨骼健康检查技术存在电离辐射,无法表征骨组织生化成分等问题,本文设计了一套超声-光声多模... 详细信息

早期诊断和治疗骨质疏松症能显著降低骨折风险。骨组织物理结构和生化成分的影像学检查对骨质疏松症的诊断具有重要意义。为了克服基于射线的骨骼健康检查技术存在电离辐射,无法表征骨组织生化成分等问题,本文设计了一套超声-光声多模态成像仪器。该仪器由波长实时可调的激光器、多模时序控制器、超声数据采集与控制器、高速数据交换与传输模块组成,利用时分复用和异步成像策略原位采集超声和光声信号,结合高分辨率成像算法获得骨组织的超声-光声影像。松质骨仿体和牛松质骨的离体试验以及手指关节在体试验结果表明,所提出的超声-光声多模态成像仪器在骨质疏松症的诊断中具有潜在的应用价值,为全面评价骨骼健康的临床研究奠定了基础。

关键词：骨质疏松超声-光声成像仪骨结构及成分表征高分率骨成像

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Necrotizing Pneumonia and Conservative Treatment: A Case Report and Review of the Literature

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Open Journal of Respiratory Diseases 2024年第3期14卷 69-76页

作者： Pedro Rogerio Magalhães Braga Eduarda Kipper Beck Carolina de Mello Viera Cecília Gatti Wolff Laura Gazal Passos Guilherme Bastos de Mello Luis Felipe Pilar Gomes Giacomo Farias Tramontin taíse Rosa de Carvalho Department of Internal Medicine Hospital So Lucas da PUCRS Porto Alegre Brazil school of Medicine Pontifcia Universidade Catlica do Rio Grande do Sul Porto Alegre Brazil Department of Radiology Hospital So Lucas da PUCRS Porto Alegre Brazil

We present a case of necrotizing pneumonia in an 87-year-old man without severe respiratory instability. Clinical suspicion arose due to the need for supplementary oxygen and persistent fever during treatment for community-acquired pneumonia. The diagnosis was confirmed by chest computed tomography. Although necrotizing pneumonia typically requires major surgical intervention upon diagnosis, we chose conservative management with antimicrobials and chest drainage alone. The patient experienced significant improvement and resolution of pneumonia with conservative management.

关键词： Respiratory Tract Infections Lung Disease Bacterial Pneumonia

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soil Respiration, Microbial Biomass and Nutrient Availability in soil After Addition of Residues with Adjusted N and P Concentrations

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Pedosphere 2017年第1期27卷 76-85页

作者： Trung ta NGUyEN Petra MARsCHNER school of Agriculture Food and Wine The University of Adelaide Adelaide 5005 (Australia)

Microbial activity and nutrient release are known to be influenced by organic matter properties,but it is difficult to separate the effect of C/N ratio from that of C/P ratio because in most plant residues both ratios are either high or *** incubation experiment was conducted to investigate the effects of reducing the C/N and C/P ratios of slowly decomposable plant residues(young eucalyptus leaves,mature wheat straw,and sawdust) to those of rapidly decomposable residues(young kikuyu shoots) on soil respiration,microbial biomass,and N and P *** C/N and C/P ratios of the former were adjusted to 15 and 89,respectively,by adding N as(NH_4)_2sO_4,P as KH_2PO_4 or both and residues were added at 10 g C kg-1 to a silt *** respiration was measured over21 d;microbial biomass C(MBC) and available N and P were measured on days 0,7,and *** to the unamended soil,addition of kikuyu increased cumulative respiration 20-fold,MBC concentration 4 to 8-fold,and available P concentration up to4-fold,whereas the increase in available N concentration was small and *** respiration and MBC concentration were low in the sawdust-amended soil and were not influenced by reducing the C/N and C/P *** respiration with original wheat and eucalyptus was 30%-40%of that with *** the C/N ratio alone or both C/N and C/P ratios increased cumulative respiration and MBC concentration 2-fold compared to the original wheat and eucalyptus,whereas reducing the C/P ratio had little *** the experiment,the available N concentration after addition of residues with reduced C/N ratio increased in the following order of eucalyptus y lowering the C/N and C/P ratios,microbial activity was more limited by C and N than ***,lowering the C/N ratio of very slowly decomposable sawdust had no effect on soil respiration and MBC concentration,suggesting that other properties such as concentration of poor

关键词： C/N ratio C/P ratio microbial activity nutrient immobilisation nutrient mineralisation

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