检索结果-南通市图书馆

The Administration of Ocoxin Increases the Quality of Life of Patients with Advanced Epithelial or Metastatic ovarian Cancer Undergoing Neoadjuvant Chemotherapy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2022年第9期13卷 561-584页

作者： Karen López Miguel Daniel Ricardo Martínez Ávila Lliset Álvarez Pérez Gisselle Martínez Rabasa Alejandro Linchenat Lambert Roberto Esperón Noa Lisandra Heredia Manzano Margarita De Quesada Amigó Rafael I. Reyes Velázquez Danay Corrales Otero Ramon Ropero Toirac Idelmis Curbelo Heredia Mircea Betancourt Cabeza Tania A. Agrelo Ramos Rosa María Muñoz Reyes Juan Jesús Lence Anta Rosalía Fuentes sosa Karelia silvera Candó Kirenia silva Rodríguez Zaida Lastre sosa Mayte Robaina García Eduardo sanz David Marquez Department of Medical Oncology INOR La Habana Cuba Department of Gynaeco-Oncology INOR La Habana Cuba Department of Anatomical Pathology INOR La Habana Cuba Department of Imaging INOR La Habana Cuba Clinical Research section INOR La Habana Cuba Department of Onco-Psychology INOR La Habana Cuba Clinical Laboratory Department INOR La Habana Cuba Clinical Trials Pharmacy Department INOR La Habana Cuba Department of Biostatistics CENCEC La Habana Cuba scientific Department CATALYSIS Madrid Spain

Background: 70% of ovarian cancer cases are diagnosed at an advanced stage (III or IV) of the disease and, in turn, with a high prevalence of peritoneal carcinosis and ascites, which leads to progressive malnutrition in patients, with the consequent deterioration of their general condition. There is a very important relationship between nutritional status, quality of life, survival, and the ability to tolerate multidisciplinary treatment of peritoneal carcinosis. Methods: A phase II, open-label, single-center, non-randomised clinical trial was conducted that included 36 patients with advanced disease who were administered the nutritional supplement Ocoxin, 30 ml twice a day, beginning one week before chemotherapy (CT) based on carboplatin/paclitaxel, of which they receive three cycles with neoadjuvant intent. Ocoxin treatment was continued during chemotherapy and for three weeks after completion of the last cycle, as well as during any periods for which this treatment was discontinued due to toxicity. The effect of Ocoxin on the quality of life was assessed through the QLQ C30 and QLQ ov28 questionnaires from the start of treatment until the end of the follow-up period. In addition, the Karnofsky Index and nutritional parameters were assessed. Results: There were no significant differences between adverse events versus baseline values, except in leukocytes, lymphocytes, neutrophils, ALT, and AsT. There was no deterioration of the QoL scales, except for those related to the effects of chemotherapy and alopecia. Conclusions: Ocoxin as an adjuvant to chemotherapy appears to improve better tolerance to chemotherapy, showed a good safety profile, and improved quality of life. For further information on Ocoxin neoadjuvant therapy benefits, a phase III clinical trial will be needed.

关键词： Chemotherapy Radiotherapy ovarian Cancer Oncology Quality of Life Ad-juvant Therapy supportive Care

激光治疗老年患者癌性气道内阻塞41例临床分析

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国实用内科杂志 2005年第4期25卷 324-325页

作者：郭纪全陈正贤李静涂海燕李惠英广东省人民医院呼吸科广州510080

目的观察掺钕饱钇铝石榴石(Nd:YAG)激光在老年患者癌性气道内阻塞治疗中的应用价值.方法广东省人民医院于1998-06～2004-12对41例老年患者癌性气道内阻塞患者经纤维支气管镜应用Nd:YAG激光进行消融,观察其疗效及并发症.结果41例患者均... 详细信息

目的观察掺钕饱钇铝石榴石(Nd:YAG)激光在老年患者癌性气道内阻塞治疗中的应用价值.方法广东省人民医院于1998-06～2004-12对41例老年患者癌性气道内阻塞患者经纤维支气管镜应用Nd:YAG激光进行消融,观察其疗效及并发症.结果41例患者均良好耐受激光治疗,激光治疗后气道直径均有所扩大,扩大(6.12±1.12)mm;气促分级减少,减少(1.85±0.57)级;1秒用力呼气容积(FEV1)增加(0.62±0.16)L;动脉血氧分压(PaO2)上升(2.8±1.4)kPa.激光治疗过程中有39例患者出现短暂性低氧血症,16例出现出血,术后有13例出现早期呼吸困难,5例出现发热,心肌梗死及急性心功能不全各1例.所有并发症经积极处理后病情均保持稳定.结论Nd:YAG激光对老年人癌性气道内阻塞的治疗安全、有效.对肺功能暂时不能耐受放化疗伴癌性气道阻塞的老年肺癌患者,可以首先选择气道内Nd:YAG激光治疗,打通气道,改善肺功能及一般情况后,再选择性地进一步其它治疗.

关键词：气道癌性激光治疗并发症老年患者耐受老年人内阻目的观结论

在线全文

学校读者我要写书评

暂无评论

33例新生儿尸检结果及临床误诊分析

南通大学学报(医学版) 1987年第2期 29-30页

作者：张德才邵钰华季忠明芦炳辉南通市第一人民医院儿科南通市第一人民医院病理科

本文对照33例尸检结果,临床误诊15例,误诊率达45.5%。误诊病例中以新生儿出血占首位,其次是先天性畸形、纵隔气肿、核黄疸等。作者认为详细询问病史(包括母孕史、出生史)、仔细体检、严密观察病情、及时作辅助检查是降低误诊率的重要环... 详细信息

本文对照33例尸检结果,临床误诊15例,误诊率达45.5%。误诊病例中以新生儿出血占首位,其次是先天性畸形、纵隔气肿、核黄疸等。作者认为详细询问病史(包括母孕史、出生史)、仔细体检、严密观察病情、及时作辅助检查是降低误诊率的重要环节,并提倡儿科医师深入产房,积极参加危重新生儿的抢救。

关键词：新生儿尸检误诊率

高度近视家族史对近视眼发病及近视程度的影响

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 32-32页

作者： s.-H.H. Juo 陈立军 Columbia University Genome Center 1150 Saint Nicholas Avenue New York NY 10032 United States

PURPOsE. To investigate the impact of a positive family history of high myopia on the level and onset of myopia and its ocular components. METHODs. A cross-s ectional study was conducted. The participants (aged 17 to 45 years) were catego rized into four groups: normal, mild, moderate, and high myopia. The age of firs t glasses for myopia was used as the onset of myopia. The impact of the family h istory on the level and the onset of myopia was quantified. Parental effect on c orneal curvature (CC), anterior chamber depth (ACD), and axial length (AXL) was analyzed. REsULTs. The study included 185 normal subjects, 170 mild, 140 moderat e, and 392 high myopes. Family history was strongly associated with the probands ’status (Ps ≥1 highlymyopic parent, the odds ratios (ORs) of developing mild or moderate myopia were between 2.5 and 3.7 (95%CI: 1 .1-6.5) and the ORs of having high myopia were >5.5 (95%CI: 3.2-12.6). A stro ng association (P=2 ×10-6) between parental myopic state and the AXL in the su bjects was also found, but there was no statistical relationship for ACD or CC. There was an association between high myopia in parents and the onset of myopia in children. siblings had a weaker association with the level of myopia and had no effect on the onset of myopia. CONCLUsIONs. This study found strong familial effects on the level and onset of myopia even after adjusting for environmental factors. The parental effect on ocular components in their offspring was primari ly on AXL.

关键词：近视程度高度近视中度近视组眼轴长度角膜曲率轻度近视先证者前房深度发病年龄横断面研究

稻子、小麦麸皮中可溶性非淀粉多糖的气相色谱法测定

在线全文

学校读者我要写书评

暂无评论

色谱 1998年第2期16卷 123-125页

作者：田福利陶克肖贵斌曹世明内蒙古大学化学系内蒙古师范大学化学系

讨论稻子、小麦麸皮中可溶性非淀粉多糖的气相色谱法测定。将稻子、小麦麸皮磨细后，用８０％乙醇萃取游离糖，剩余物在醋酸缓冲液（ｐＨ５．０）条件下分别用α－淀粉酶和α－葡萄糖苷酶酶解，除掉淀粉。非淀粉多糖用酸水解为各单糖，... 详细信息

讨论稻子、小麦麸皮中可溶性非淀粉多糖的气相色谱法测定。将稻子、小麦麸皮磨细后，用８０％乙醇萃取游离糖，剩余物在醋酸缓冲液（ｐＨ５．０）条件下分别用α－淀粉酶和α－葡萄糖苷酶酶解，除掉淀粉。非淀粉多糖用酸水解为各单糖，采用糖醇衍生化成乙酸酯的制备方法，用ＯＶ－１７０１石英毛细管色谱柱，可分离得到非淀粉多糖（ＮＳＰ）各组成单糖的色谱峰。并以自然界中不存在的阿洛糖作内标物，提高了定性定量分析的准确性，计算出了稻子、小麦麸皮中可溶性非淀粉多糖的含量。

关键词：稻子小麦麸皮可溶性非淀粉多糖 GC NsP

在线全文

学校读者我要写书评

暂无评论

新生儿复苏术的疗效研究:早期预后性变量

世界核心医学期刊文摘（儿科学分册） 2006年第1期2卷 10-10页

作者： saugstad O.D. Ramji s Rootwelt T. Vento M. 张振 Pediatrisk Forskni ngsinstitutt Rikshospitalet University Hospital Sognsvannsvn 20NO-0027 Oslo Norway

Aim: To characterize the development of clinically relevant variables the firs t minutes after birth and identify early prognostic markers in newborn infants r equiring resuscitation. Methods: A database of 591 infants resuscitated with eit her 21%or 100%oxygen was analysed. Time to first breath, development in heart rate, Apgar scores, arterial oxygen saturation (saO2), and base deficit (BD) are described in relation to different degrees of birth depression and outcomes. Re sults: Heart rate and Apgar scores increased quickly even in the most depressed infants but were significantly lower in those having a poor outcome. By contrast , BD normalized at the same rate, 6-7 mmol/l/h, in the first hour of life regar dless of the degree of birth depression and outcome. saO2 values increased as qu ickly in room air as in 100%-oxygen-resuscitated infants. Time to first breat h was prolonged threefold, from 1 to 3 min, in the most depressed (1-min Apgar score ss depressed infants. Highest odds ratio (OR) for death in the first week of life or for development of hypoxic-ischaemic enceph alopathy (HIE) stage 2 and 3 was a 5-min heart rate ≤60 bpm (OR 16.5 for both death and HIE) and Apgar survival for HIE stage 1, 2, and 3 was 93%, 63%, and 11%, respectively. OR for early neonatal death, i f saO2 ≤60%at 1 min, was 8.6 (sensitivity 0.82 and specificity 0.65). Conclusi on: Apgar scores, heart rate, saO2, and time to first breath in newly born infan ts in need of resuscitation may be used for early identification of infants with a poor prognosis. These data may be helpful in describing the severity of depre ssion in single infants and to select infants in need of interventional therapy.

关键词：复苏术疗效研究出生后缺血缺氧性脑病抑制程度动脉血氧饱和度抑制组比值比早期鉴别生时

欧洲森林碳汇能力的新估算方法——综合通量测定、现场调查和空间观察:0.17～0.35Gt(C)

在线全文

学校读者我要写书评

暂无评论

人类环境杂志 1998年第7期27卷 582-584页

作者： Philippe H. Martin jrc. ithttp://www.jrc. org/jrc/ R Valentini M. Jacques K. Fabbri D. Galatl R. Quaratlno J.B. Moncrleff P. Jarvis N.O.Jensen A. Lindroth A. Grelle *** R. Ceulemans A.s. Kowalski T. Vesala P. Keronen G. Matteucci A. Gralner P. Berbingier D. Loustau E.-D.schulze J. Tenhunen C. Rebman A.J. Dolman J.E. Elbers C.Bernhofer T. Grunwald H.Thorgeirsson P.Kennedy s.Folving 习小环 Institute for systems Informaticsand Safety European Commission JointResearch CentreTP 6SOVia E. Fermi 121020 Ispra (VA)ItalyPhilippemartin University of Tuscia Department of Forest Science and Environment Vlterbo Italy http://www. unitus. it/eflux/who.html Institute for systems Informatics and Safety European Commission Joint Research Centre 1-21020 Ispra (VA) Italy http://www. emap. sai.jrc. it/forecast/fi http://www. emap. sai.jrc. it/forecast/firs/

陆地生物圈对温室气体(GHGs)提供了一个强大的汇。全球研究表明,陆地生物圈吸收了相当数量的CO_2,但是关于世界不同的地理区域和生态系统对CO_2汇功能所起的作用还不十分清楚。即将出版的《Ambio》杂志中的一篇文章概要论述了欧洲森林(... 详细信息

陆地生物圈对温室气体(GHGs)提供了一个强大的汇。全球研究表明,陆地生物圈吸收了相当数量的CO_2,但是关于世界不同的地理区域和生态系统对CO_2汇功能所起的作用还不十分清楚。即将出版的《Ambio》杂志中的一篇文章概要论述了欧洲森林(EU)对CO_2吸收的重要作用。1997年12月11日随着《联合国气候变化框架公约》的京都协议的签署。

关键词：森林碳汇能力估算法综合通量调查空间观测