检索结果-南通市图书馆

On Approximation by Interpolating polynomials in Cωp spaces

在线全文

学校读者我要写书评

暂无评论

Journal of Mathematical Research with Applications 1993年第3期 465-469页

作者： s.p.zhou Dept.of Math. Univ.of Alberta Edmonton Alberta Canada T6G 2G1

This note gives a counterexample which in particular shows that a mainresult of a paper in *** is not correct.

关键词： p spaces On Approximation by Interpolating polynomials in C

sIMULTANEOUsE AppROXIMATION TO A DIFFERENTIABLE FUNCTION AND ITs DERIVATIVEs BY LAGRANGE INTERpOLATING pOLYNOMIALs

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Analysis in Theory and Applications 1994年第4期10卷 100-109页

作者： T.F.Xie s.p.zhou China Institute of Metrology China Universy of Alberta Canada

This paper establishes the following pointwise result for simultancous Lagrange imterpolating approxima- tion:,then |f^(k)(x)-p_n^(k)(f,x)|=O(1)△_n^(q-k)(x)ω where p_n(f,x)is the Lagrange interpolating potynomial of... 详细信息

关键词： sIMULTANEOUsE AppROXIMATION TO A DIFFERENTIABLE FUNCTION AND ITs DERIVATIVEs BY LAGRANGE INTERpOLATING pOLYNOMIALs AppI Zr

A COUNTEREXAMpLE ON MONOTONE MuNTZ AppROXIMATION Ⅱ

在线全文

学校读者我要写书评

暂无评论

Analysis in Theory and Applications 1996年第4期12卷 111-112页

作者： s.p.zhou Hangzhou University China

We adopt the following symbols and notations. Let C;be the class of all real continuous functions in [0,1] which have N continuousderivatives, L;0,1];be the space of real pth power integrable functions on [0,1], and ... 详细信息

关键词： real A COUNTEREXAMpLE ON MONOTONE MuNTZ AppROXIMATION lim than

Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： siva s.V.p.sakamuri Anil sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular Biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:Hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

Induced pluripotent stem cell-related approaches to generate dopaminergic neurons for parkinson's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3193-3206页

作者： Ling-Xiao Yi Hui Ren Woon Genevieve saw Li Zeng Eng King Tan Zhi Dong zhou National Neuroscience Institute Singapore Nanyang Technology University Singapore Department of Neurology Singapore General HospitalSingapore signature Research program in Neuroscience and Behavioral Disorders Duke-NUS Medical SchoolSingapore

The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of parkinson's disease,the second most common human neurodegenerative *** the detailed pathogenesis accounting for dopaminergic neuron degeneration in parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for parkinson's disease research and *** induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of parkinson's disease pathogenesis and contributed to anti-parkinson's disease *** current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem *** benefits of induced pluripotent stem cell-based research are *** dopaminergic neuron differentiation protocols from induced pluripotent stem cells are *** emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are ***,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for parkinson's disease.

关键词： dopaminergic neurons induced pluripotent stem cells parkinson's disease stem cell approaches

Interannual variability of boreal summer intraseasonal oscillation over the northwestern pacific influenced by the pacific Meridional Mode

在线全文

学校读者我要写书评

暂无评论

Atmospheric and Oceanic science Letters 2025年第1期18卷 6-11页

作者： Haoyu zhou pang-Chi Hsu Lin Chen Yitian Qian Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environmental Change/Collaborative Innovation Center on Forecast and Evaluation of Meteorological DisastersNanjing University of Information Science and TechnologyNanjingChina

During the boreal summer,intraseasonal oscillations exhibit significant interannual variations in intensity over two key regions:the central-western equatorial pacific(5°s-5°N,150°E-150°W)and the subtropical Northwestern pacific(10°-20°N,130°E-175°W).The former is well-documented and considered to be influenced by the ENsO,while the latter has received comparatively less attention and is likely influenced by the pacific Meridional Mode(pMM),as suggested by partial correlation analysis *** elucidate the physical processes responsible for the enhanced(weakened)intraseasonal convection over the subtropical northwestern pacific during warm(cold)pMM years,the authors employed a moisture budget *** findings reveal that during warm pMM years,there is an increase in summer-mean moisture over the subtropical northwestern *** increase interacts with intensified vertical motion perturbations in the region,leading to greater vertical moisture advection in the lower troposphere and consequently resulting in convective *** a process is pivotal in amplifying intraseasonal convection *** observational findings were further verified by model experiments forced by pMM-like sea surface temperature patterns.

关键词： Boreal summer intraseasonal oscillation Interannual variability pacific Meridional Mode Moisture budget analysis

The emerging role of nitric oxide in the synaptic dysfunction of vascular dementia

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 402-415页

作者： Xiaorong Zhang Zhiying Chen Yinyi Xiong Qin zhou Ling-Qiang Zhu Dan Liu Department of pathology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Jiujiang Clinical precision Medicine Research Center JiujiangJiangxi ProvinceChina Center for Cognitive science and Transdisciplinary studies Jiujiang UniversityJiangxi ProvinceChina Department of Neurology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Rehabilitation Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of pathophysiology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

With an increase in global aging,the number of people affected by cerebrovascular diseases is also increasing,and the incidence of vascular dementia-closely related to cerebrovascular risk-is increasing at an epidemic ***,few therapeutic options exist that can markedly improve the cognitive impairment and prognosis of vascular dementia *** in Alzheimer’s disease and other neurological disorders,synaptic dysfunction is recognized as the main reason for cognitive *** oxide is one of the ubiquitous gaseous cellular messengers involved in multiple physiological and pathological processes of the central nervous ***,nitric oxide has been implicated in regulating synaptic plasticity and plays an important role in the pathogenesis of vascular *** review introduces in detail the emerging role of nitric oxide in physiological and pathological states of vascular dementia and summarizes the diverse effects of nitric oxide on different aspects of synaptic dysfunction,neuroinflammation,oxidative stress,and blood-brain barrier dysfunction that underlie the progress of vascular ***,we propose that targeting the nitric oxide-sGC-cGMp pathway using certain specific approaches may provide a novel therapeutic strategy for vascular dementia.

关键词： endoplasmic reticulum stress endothelial nitric oxide synthase gene therapy nitric oxide NO-sGC-cGMp pathway synaptic dysfunction vascular dementia

Revisiting cerebral endothelial cells in Alzheimer’s disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neurosurgery University Hospital BonnBonnGermany

Alzheimer’s disease(AD)is the most common neurodegenerative disorder characterized by slow and progressive decline of cognitive and memory *** only approximately 5%of the cases,AD is familial,as often predisposed by genetic mutations(Hoogmartens et al.,2021),while sporadic AD accounts for approximately 95%of the *** amyloid cascade hypothesis is one of the fundamental hypotheses put out to explain AD pathogenesis as dysregulated homeostasis of amyloid-β(Aβ)peptides that leads to the accumulation of Aβplaques in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

The cGAs-sTING-interferon regulatory factor 7 pathway regulates neuroinflammation in parkinson's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： shengyang zhou Ting Li Wei Zhang Jian Wu Hui Hong Wei Quan Xinyu Qiao Chun Cui Chenmeng Qiao Weijiang Zhao Yanqin shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation parkinson’s disease RU521 sTING type I interferon