检索结果-南通市图书馆

Making More Food Available:Promoting sustainable Agricultural Production

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2012年第1期11卷 1-8页

作者： Rudy Rabbinge Prem s Bindraban Food security and sustainable Development IsRIC-World soil Information Plant Research International

During the 20th century food availability worldwide has increased considerably. The increase in population was outnumbered by the productivity increase in agriculture mainly by higher yields per ha. Globally there is more food available per person than ever before. In the coming decades the world population will further increase and diets will change requiring a doubling of plant production worldwide by 2050. Especially the increase in demand will be substantial in Asia and snb-saharan Africa.

关键词： DEFOREsTATION sYsTEMs ENERGY INPUT

Investigation of mitigating effect of colon-specific prodrugs of boswellic acid on 2,4,6-trinitrobenzene sulfonic acidinduced colitis in Wistar rats: Design, kinetics and biological evaluation

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第7期23卷 1147-1162页

作者： Ajinkya sarkate suneela s Dhaneshwar Department of Pharmaceutical Chemistry Poona College of PharmacyBharati Vidyapeeth UniversityMaharashtra 411038India

AIM To develop a colon-targeting bioreversible delivery system for β-boswellic acid(BBA) and explore utility of its prodrugs in 2,4,6-trinitrobenzene sulfonic acid(TNBs)-induced colitis in *** synthesis of 4 co-drugs of BBA with essential amino acids was achieved by CDI coupling, followed by their spectral characterization. In vitro kinetics were studied by HPLC in aqueous buffers, homogenates of gastrointestinal tract and fecal matter. In vivo kinetic studies were performed in Wistar rat plasma, urine and feces. The prodrugs were screened in TNBs-induced colitis modeled Wistar rats. statistical significance was assumed at P sease controls using one-way and two-way *** Prodrugs were stable in 0.05 mol/L HCl buffer(p H 1.2) and stomach homogenates. Negligible hydrolysis was observed in phosphate buffer and intestinal homogenates. substantial release(55%-72% and 68%-86%) of BBA was achieved in rat fecal matter and homogenates of colon. In vivo studies of BBA with L-tryptophan(BT) authenticated colon-specific release of BBA. But, surprisingly substantial concentration of BBA was seen to reach the systemic circulation due to probable absorption through colonic mucosa. sitespecifically enhanced bioavailability of BBA could be achieved in colon, which resulted in demonstration of significant mitigating effect on TNBs-induced colitis in rats without inducing any adverse effects on stomach, liver and pancreas. Prodrug of BT was found to be 1.7%(P superior than sulfasalazine in reducing the inflammation to colon among all prodrugs tested. CONCLUsION The outcome of this study strongly suggests that these prodrugs might have dual applicability to inflammatory bowel disease and chronotherapy of rheumatoid arthritis.

关键词：煽动性的肠疾病 Boswellic 酸互补、其他的药指向冒号相互的 prodrugs 氨基酸导致 TNBs 的大肠炎

A Hybrid Immigrants scheme for Genetic Algorithms in Dynamic Environments

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2007年第3期4卷 243-254页

作者： shengxiang Yang Renato Tinós Department of Computer science University of LeicesterLeicester LE1 7RHUK Department of Physics and Mathematics FFCLRPUniversity of Sao PauloRibeir Preto 14040-901Brazil

Dynamic optimization problems are a kind of optimization problems that involve changes over time. They pose a serious challenge to traditional optimization methods as well as conventional genetic algorithms since the goal is no longer to search for the optimal solution（s） of a fixed problem but to track the moving optimum over time. Dynamic optimization problems have attracted a growing interest from the genetic algorithm community in recent years. several approaches have been developed to enhance the performance of genetic algorithms in dynamic environments. One approach is to maintain the diversity of the population via random immigrants. This paper proposes a hybrid immigrants scheme that combines the concepts of elitism, dualism and random immigrants for genetic algorithms to address dynamic optimization problems. In this hybrid scheme, the best individual, i.e., the elite, from the previous generation and its dual individual are retrieved as the bases to create immigrants via traditional mutation scheme. These elitism-based and dualism-based immigrants together with some random immigrants are substituted into the current population, replacing the worst individuals in the population. These three kinds of immigrants aim to address environmental changes of slight, medium and significant degrees respectively and hence efficiently adapt genetic algorithms to dynamic environments that are subject to different severities of changes. Based on a series of systematically constructed dynamic test problems, experiments are carried out to investigate the performance of genetic algorithms with the hybrid immigrants scheme and traditional random immigrants scheme. Experimental results validate the efficiency of the proposed hybrid immigrants scheme for improving the performance of genetic algorithms in dynamic environments.

关键词： Genetic algorithms random immigrants elitism-based immigrants dualism dynamic optimization problems.

Ultrasound Assisted synthesis of starch Nanocrystals and It’s Applications with Polyurethane for Packaging Film

在线全文

学校读者我要写书评

暂无评论

Journal of Renewable Materials 2020年第3期8卷 239-250页

作者： Vikas s.Hakke Uday D.Bagale sami Boufi G.Uday Bhaskar Babu shirish H.sonawane Department of Chemical Engineering National Institute of TechnologyWarangal(TS)506004India University of sfax Sfax Faculty of ScienceLMSESfaxTunisia

starch nanocrystals(sNC)were prepared from maize starch using ultrasound assisted acid *** process takes less time for the generation of sNC,which is advantageous over conventional acid *** synthesized sNC were characterized using X-ray diffraction,dynamic light scattering,zeta potential and transmission electron microscopy(TEM).Particle size and TEM data show that the particles were near to 150 nm,with oval *** sNC with higher surface charge are obtained with this innovative approach as compared to conventional acid *** of high surface charge and oval like morphology,the sNC performed well in reinforcing a polyurethane *** rise in crystallinity by 16%was observed due to ultrasound *** the lower concentration of sNC in nanocomposite film,dynamic mechanical analysis demonstrated meaningful increment in mechanical properties of polyurethane nanocomposite *** decrease in chain slippage over the glass transition temperature was observed because of the sNC reinforcement in polyurethane *** to the conventional acid hydrolysis,the present approach for the synthesis of starch nanocrystals is much faster and easier.

关键词： starch nanocrystal ultrasound acid-hydrolysis nanocomposite TEM

Complexity of Gold(Ⅲ)Ion With Cefotaxime and Cefepime Drugs:spectroscopic,Antimicrobial and Antitumor Discussions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

光谱学与光谱分析 2020年第10期40卷 3315-3320页

作者： Lamia A Albedair samar O Aljazzar Mohamed I Kobeasy Moamen s Refat College of science Princess Nourah bint Abdulrah man UniversityDepartment of ChemistrySaudi Arabia Department of Biochemistry Faculty of AgricultureCairo UniversityGizaEgypt Department of Chemistry Faculty of ScienceTaif UniversityAl-HawiahTaif 21974Saudi Arabia Department of Chemistry Faculty of SciencePort Said UniversityPort SaidEgypt

The availability of chemical and biological data presented in this paper is the basis for understanding not only the current state of anti-cancer drugs based on gold(Ⅲ),but also the rationale for strategies for future drug *** Au(Ⅲ)nanosized complexes of cefotaxime(ceph-3)and cefepime(ceph-4)ligands as a 3rd and 4th of cephalosporin generation drugs were ***(Ⅲ)complexes were discussed based on the elemental,molar conductance,thermal and magnetic moment measurements as well as spectral(FTIR,1HNMR,UV-Vis,and XRD)***-IR spectra revealed that the ceph-3 and ceph-4 ligands reacted as a bidentate ligands through carboxylate oxygen andβ-lactam oxygen *** analytical analysis confirm that the molar ratio is 1∶1(Au 3+/ceph)with general formula[Au(L)(Cl)2]where L=ceph-3 or *** structures of Au(Ⅲ)complexes were presence as a square planar geometry.X-ray diffraction patterns referred to a crystalline nature for all synthesized *** analyses confirmed that the synthetic gold(Ⅲ)complexes have a nanosized *** vitro antimicrobial activities of Au(Ⅲ)complexes were evaluated towards two types of bacteria(G+&G-).The antitumor activities of gold(Ⅲ)complexes are appraised against breast(MCF-7)and colorectal adenocarcinoma(Caco-2)cell lines,which means that the two complexes may consider promising anticancer drugs.

关键词： Cefotaxime sodium Cefepime hydrochloride Complexity Gold(Ⅲ)ions Nanoscale structure anticancer

Aerodynamics of ducted re-entry vehicles

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2020年第7期33卷 1837-1849页

作者： C.ANBU sERENE RAJ M.NARAsIMHAVARADHAN N.VAIsHNAVI s.ARUNVINTHAN A.AL ARJANI s.NADARAJA PILLAI Turbulence&Flow Control Lab School of Mechanical EngineeringSASTRA Deemed UniversityTamil Nadu 613401India College of Engineering Prince Sattam Bin Abdelaziz University(PSAU)Alkharj 11942Saudi Arabia

Ballistic parameter plays a major role in determining the re-entry *** ballistic coefficient offers an optimal re-entry,wherein the vehicle decelerates higher up in the atmosphere thereby decreasing the imposed aerothermal *** current computational study proposes an add-on,to the existing Orion-based re-entry vehicle:a duct circumventing the capsule from the shoulder to the base,to improve the aerocapture ability of the re-entry *** design cases are categorised based on a non-dimensional parameter termed the Annular Area Ratio(AAR).Dragand ballistic coefficient of the Ducted Re-entry Vehicles(DRVs)at various Mach numbers are evaluated and compared with those of the baseline *** results show that the proposed design increases the drag for all the AARs considered in the subsonic *** the supersonic regime,ducted models of higher AAR are more promising with the increase in Mach *** also exhibit lower ballistic coefficients than their baseline counterparts.

关键词： Aerocapture Annular area ratio(AAR) Ballistic coefficient CFD Re-entry

An ecological model with the p-Laplacian and diffusion

在线全文

学校读者我要写书评

暂无评论

International Journal of Biomathematics 2016年第1期9卷 157-163页

作者： s. H. Rasouli Department of Mathematics Faculty of Basic Sciences Babol University of Technology Babol Iran

We study the existence of positive solutions of a population model with diffusion of the form where Δ p denotes the p-Laplacian operator defined by Δ p z = div (∣∇z∣ p-2 ∇z), p > 1, Ω is a bounded domain of R N with smooth boundary, α ∈ (0, 1), a and c are positive constants. Here f : [0, ∞) → R is a continuous function. This model arises in the studies of population biology of one species with u representing the concentration of the species. We discuss the existence of positive solution when f satisfies certain additional conditions. We use the method of sub- and super-solutions to establish our results.

关键词：生态模型 p-Laplacian算子扩散正解的存在性种群生物学种群模型连续函数附加条件

Expression of genes that control core fucosylation in hepatocellular carcinoma: systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2019年第23期25卷 2947-2960页

作者： Pamela A Norton Anand s Mehta Department of Microbiology and Immunology Drexel University College of MedicinePhiladelphiaPA 19102United States Department of Cell and Molecular Pharmacology Medical University of South CarolinaCharlestonSC 29425United States

BACKGROUND Changes in N-linked glycosylation have been observed in the circulation of individuals with hepatocellular carcinoma. In particular, an elevation in the level of core fucosylation has been observed. However, the mechanisms through which core fucose is increased are not well understood. We hypothesized that a review of the literature and related bioinformatic review regarding six genes known to be involved in the attachment of core fucosylation, the synthesis of the fucosylation substrate guanosine diphosphate(GDP)-fucose, or the transport of the substrate into the Golgi might offer mechanistic insight into the regulation of core fucose *** To survey the literature to capture the involvement of genes regulating core Nlinked fucosylation in hepatocellular carcinoma METHODs The PubMed biomedical literature database was searched for the association of hepatocellular carcinoma and each of the core fucose-related genes and their protein products. We also queried The Cancer Genome Atlas Liver hepatocellular carcinoma(LIHC) dataset for genetic, epigenetic and gene expression changes for the set of six genes using the tools at *** A total of 27 citations involving one or more of the core fucosylation-related genes(FPGT, FUK, FUT8, GMDs, sLC35 C1, TsTA3) and hepatocellular carcinoma were identified. The same set of gene symbols was used to query the371 patients with liver cancer in the LIHC dataset to identify the frequency of m RNA over or under expression, as well as non-synonymous mutations, copy number variation and methylation level. Although all six genes trended to moresamples displaying over expression relative to under-expression, it was noted that a number of tumor samples had undergone amplification of the genes of the de novo synthesis pathway, GMDs(27 samples) and TsTA3(78 samples). In contrast, the other four genes had undergone amplification in 2 or fewer *** Amplification of genes involved in the de novo pathway

关键词： Liver cancer N-linked glycosylation Fucose Guanosine diphosphate fucose Hepatocellular carcinoma

synchronization Phenomena Investigation of a New Nonlinear Dynamical system 4D by Gardano’s and Lyapunov’s Methods

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2021年第3期66卷 3311-3327页

作者： Abdulsattar Abdullah Hamad Ahmed s.Al-Obeidi Enas H.Al-Taiy Osamah Ibrahim Khalaf Dac-Nhuong Le school of Mathematics Madurai Kamaraj UniversityMadurai625021India specialty of Mathematics Gifted School of NinevehMosulIraq Al-Nahrain University Baghdad70030Iraq Institute of Research and Development Duy Tan UniversityDanang550000Vietnam Faculty of Information Technology Duy Tan UniversityDanang550000Vietnam

synchronization is one of the most important characteristics of dynamic *** this paper,the authors obtained results for the nonlinear systems controller for the custom synchronization of two 4D *** findings have allowed authors to develop two analytical approaches using the second Lyapunov(Lyp)method and the *** the Gardano method does not involve the development of special positive Lyp functions,it is very efficient and convenient to achieve excessive systemsYCR *** is overcome by using Gardano and overcoming some problems in *** we get a great investigation into the convergence of error dynamics,the authors in this paper are interested in giving numerical simulations of the proposed model to clarify the results and check them,an important aspect that will be studied is synchronization Complete hybrid sYCR and anti-synchronization,by making use of the Lyapunov expansion analysis,a proposed control method is developed to determine the *** basic idea in the proposed way is to receive the evolution of between two ***,the present model has been applied and showing in a new attractor,and the obtained results are compared with other approximate results,and the nearly good coincidence was obtained.

关键词： Chaos Lu model anti-synchronization hybrid synchronization Gardano’s method nonlinear dynamical system