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science china(Information sciences) 2024年第7期67卷 224-239页

作者： Zhijia ZhAO Jiale WU Zhijie lIU We he c.l.Philip cheN school of mechanical and electrical engineering Guangzhou University school of Intelligence science and Technology and Key laboratory of Intelligent Bionic Unmanned systems of ministry of education University of Science and Technology Beijing school of computer science and engineering South China University of Technology Pazhou lab

In this study, an adaptive neural network(NN) control is proposed for nonlinear two-degree-offreedom(2-DOF) helicopter systems considering the input constraints and global prescribed ***, radial basis function NN(RBFNN) is employed to estimate the unknown dynamics of the helicopter system. second, a smooth nonaffine function is exploited to approximate and address nonlinear constraint functions. subsequently, a new prescribed function is proposed, and an original constrained error is transformed into an equivalent unconstrained error using the error transformation and barrier function transformation methods. The analysis of the established lyapunov function proves that the controlled system is globally uniformly bounded. Finally, the simulation and experimental results on a constructed Quanser's test platform verify the rationality and feasibility of the proposed control.

关键词： adaptive NN control 2-DOF helicopter global prescribed performance input constraints

Are there sex-based disparities in cataract surgery?

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International Journal of Ophthalmology(english edition) 2024年第1期17卷 137-143页

作者： matthew D.Geiger Anne m.lynch Alan G.Palestine Nathan c.Grove Karen l.christopher Richard s.Davidson michael J.Taravella Naresh mandava Jennifer l.Patnaik Department of Ophthalmology University of Colorado School of MedicineAuroraCO 80045USA

AIm:To investigate sex-based differences in the occurrence of intra-operative and post-operative complications and associated visual outcomes following cataract ***:This was a retrospective study of patients who had phacoemulsification cataract surgery at the University of colorado school of *** collected included the patient’s health history,ocular comorbidities,operative and post-operative complications,and the post-operative best corrected visual acuity(BcVA).The data were analyzed using univariate and multivariable logistic regression with generalized estimating equations to account for the correlation of some patients having two eyes included in the ***:A total of 11977 eyes from 7253 patients were included in the *** comorbidities differed by sex,with males having significantly higher percentages of traumatic cataracts(males 0.7%vs females 0.1%),prior ocular surgery(6.7%vs 5.5%),and mature cataracts(2.8%vs 1.9%).conversely,females had significantly higher rates of pseudoexfoliation(2.0%vs 3.2%).In unadjusted analysis,males had higher rates of posterior capsular rupture(0.8%vs 0.4%)and vitreous loss(1.0%vs 0.6%),but this difference was not significant after adjustment for *** had a significantly increased risk of post-operative retinal detachment,but in multivariable analysis this was no longer *** were significantly less likely to undergo post-operative neodymium-doped yttrium aluminum garnet(Nd:YAG)laser capsulotomy for posterior capsule opacification(OR=0.8,95%cI=0.7-0.9,P=0.0005).The BcVA was slightly worse for males pre-operatively;but post-operatively,both sexes exhibited similar visual acuity of snellen equivalent 20/***:The study finds that in a cohort of patients presenting for cataract surgery,sex differences exist in pre-operative comorbidities and surgical characteristics that contribute to higher rates of some complications for ***,observed surgical complicatio

关键词： cataract surgery sex-based disparity phacoemulsification outcomes

All-electron basis sets for h to Xe specific for ZORA calculations:Applications in atoms and molecules

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chinese Physics B 2024年第8期33卷 238-246页

作者： c.s.Gomes F.e.Jorge A.canal Neto Departamento de Fisica Universidade Federal do Espirito Santo29075-910 VitoriaESBrazil Departamento de Fisica Instituto de Ciencias Exatas e BiologicasUniversidade Federal de Ouro Preto Campus Universitario Morro do Cruzeiro35402-136 Ouro PretoMGBrazil

A segmented basis set of quadruple zeta valence quality plus polarization functions(QZP)for h through Xe was developed to be used in conjunction with the ZORA *** set was augmented with diffuse functions to describe electrons farther away from the nuclei *** the ZORA-ccsD(T)/QZP-ZORA theoretical model,atomic ionization energies and bond lengths,harmonic vibrational frequencies,and atomization energies of some molecules were *** addition of core-valence corrections has been shown to improve the agreement between theoretical and experimental results for molecular *** atomization energies,a similar observation emerges when considering spin-orbit *** the augmented QZP-ZORA set,static mean dipole polarizabilities of a set of atoms were calculated and compared with previously published recommended and experimental *** evaluations of the ZORA and Douglas–Kroll–hess hamiltonians were made for each property studied.

关键词： QZP-ZORA and AQZP-ZORA basis sets elements from h to Xe ccsD(T)method atomic and molecular properties

Translating Pathological Brain Activity Primers in Parkinson’s Disease Research

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Research 2024年第1期2023卷 735-752页

作者： Daniela mirzac svenja l.Kreis heiko J.luhmann Gabriel Gonzalez-escamilla sergiu Groppa movement Disorders and Neurostimulation Department of NeurologyFocus Program Translational NeuroscienceRhine Main Neuroscience NetworkUniversity Medical Center of the Johannes Gutenberg University Mainz55131 MainzGermany Institute of Physiology University Medical Center of the Johannes Gutenberg University Mainz55131 MainzGermany

Translational experimental approaches that help us better trace Parkinson’s disease(PD)pathophysiological mechanisms leading to new therapeutic targets are urgently *** this article,we review recent experimental and clinical studies addressing abnormal neuronal activity and pathological network oscillations,as well as their underlying mechanisms and *** aim is to enhance our knowledge about the progression of Parkinson's disease pathology and the timing of its symptom’s ***,we present mechanistic insights relevant for the generation of aberrant oscillatory activity within the cortico-basal ganglia *** summarize recent achievements extrapolated from available PD animal models,discuss their advantages and limitations,debate on their differential applicability,and suggest approaches for transferring knowledge on disease pathology into future research and clinical applications.

关键词： clinical knowledge insight

In vivo measurement of NADh fluorescence lifetime in skeletal muscle via -ber-coupled time-correlated single photon counting

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Journal of Innovative Optical health sciences 2024年第1期17卷 121-134页

作者： Kathryn m.Priest Jacob V.schluns Nathania Nischal colton l.Gattis Jeffrey c.Wolchok Timothy J.muldoon Department of Biomedical engineering University of Arkansas FayettevilleARUSA

Nicotinamide adenine dinucleotide(NADh)is a cofactor that serves to shuttle electrons during metabolic processes such as glycolysis,the tricarboxylic acid cycle,and oxidative phosphorylation(OXPhOs).NADh is autofluorescent,and itsfluorescence lifetime can be used to infer metabolic dynamics in living ***-coupled time-correlated single photon counting(TcsPc)equipped with an implantable needle probe can be used to measure NADh lifetime in vivo,enabling investigation of changing metabolic demand during muscle contraction or tissue *** study illustrates a proof of concept for point-based,minimally-invasive NADhfluorescence lifetime measurement in *** muscle loss(Vml)injuries were created in the left tibialis anterior(TA)muscle of male sprague Dawley *** lifetime measurements were collected before,during,and after a 30 s tetanic contraction in the injured and uninjured TA muscles,which was subsequently-t to a biexponential decay model to yield a metric of NADh utilization(cytoplasmic vs protein-bound NADh,the A11/A22 ratio).On average,this ratio was higher during and after contraction in uninjured muscle compared to muscle at rest,suggesting higher levels of free NADh in contracting and recovering muscle,indicating increased rates of *** injured muscle,this ratio was higher than uninjured muscle overall but decreased over time,which is consistent with current knowledge of inflammatory response to injury,suggesting tissue regeneration has *** data suggest that-ber-coupled TcsPc has the potential to measure changes in NADh binding in vivo in a minimally invasive manner that requires further investigation.

关键词： Glycolysis oxidative phosphorylation energy metabolism volumetric muscle loss

saliency-guided meta-hallucinator for few-shot learning

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science china(Information sciences) 2024年第10期67卷 189-210页

作者： hongguang ZhANG chun lIU Jiandong WANG linru ma Piotr KONIUsZ Philip h.s.TORR lin YANG systems engineering Institute Academy of Military Sciences Data61 Commonwealth Scientific and Industrial Research Organisation Australian National University Oxford University

learning novel object concepts from limited samples remains a considerable challenge in deep learning. The main directions for improving the few-shot learning models include(i) designing a stronger backbone,(ii) designing a powerful(dynamic) meta-classifier, and(iii) using a larger pre-training set obtained by generating or hallucinating additional samples from the small scale dataset. In this paper, we focus on item(iii) and present a novel meta-hallucination strategy. Presently, most image generators are based on a generative network(i.e., GAN) that generates new samples from the captured distribution of images. however, such networks require numerous annotated samples for training. In contrast, we propose a novel saliency-based end-to-end meta-hallucinator, where a saliency detector produces foregrounds and backgrounds of support images. such images are fed into a two-stream network to hallucinate feature samples directly in the feature space by mixing foreground and background feature samples. Then, we propose several novel mixing strategies that improve the quality and diversity of hallucinated feature ***, as not all saliency maps are meaningful or high quality, we further introduce a meta-hallucination controller that decides which foreground feature samples should participate in mixing with backgrounds. To our knowledge, we are the first to leverage saliency detection for few-shot learning. Our proposed network achieves state-of-the-art results on publicly available few-shot image classification and anomaly detection benchmarks, and outperforms competing sample mixing strategies such as the so-called manifold mixup.

关键词： few-shot learning saliency detection object recognition anomaly detection computer vision

A single degenerated primer significantly improves cOX1 barcoding performance in soil nematode community profiling

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soil ecology letters 2024年第2期6卷 31-44页

作者： Yincai Ren Dorota l. Porazinska Quanhui ma shuhan liu hongmei li Xue Qing Department of Plant Pathology Nanjing Agricultural UniversityNanjing210095China Department of entomology and Nematology University of FloridaGainesvilleFL32611USA Institute of Grassland science Key Laboratory of Vegetation Ecology of the Ministry of EducationJilin Songnen Grassland Ecosystem National Observation and Research StationNortheast Normal UniversityChangchun130024China

A new cOX1 primer for soil nematode metabarcoding was designed,and this primer outperforms other commonly used cOX1 primer pairs in species recovery and quantity of PcR products.•The lack of reference database is the main reason that led to the low species recovery in cOX1 metabarcoding.•We expanded current NcBI database by adding 51 newly generated cOX1 reference *** nematodes play important roles in soil ecosystems and often serve as bioindicators of soil *** identification of soil nematodes is often difficult due to their limited diagnostic characters and high phenotypic *** barcoding and metabarcoding techniques are promising but lack universal primers,especially for mitochondrial cOX1 *** this study a degenerated cOX1 forward primer cOIFGeD was *** primer pair(cOIFGeD/JB5GeD)outperforms other four commonly used cOX1 primer pairs in species recovery and quantity of polymerase chain reaction(PcR)*** metabarcoding analysis,the reads obtained from the new primer pair had the highest sequencing saturation threshold and amplicon sequence variant(AsV)diversity in comparison to other cOX1 as well as 18s rRNA *** annotation of AsVs suggested the new primer pair initially recovered 9 and 6 out of 25 genera from mock communities,respectively,outperformed other cOX1 primers,but underperformed the widely used 18s NF1/18sr2b primers(16 out of 25 genera).By supplementing the cOX1 database with our reference sequences,we recovered an additional 6 mock community species bringing the tally closer to that obtained with 18s *** summary,our newly designed cOX1 primers significantly improved species recovery and thus can be supplementary or alternative to the conventional 18s metabarcoding.

关键词： degenerated primers DNA metabarcoding mitochondrial cytochrome oxidase c subunit I gene phylogeny ribosomal RNA gene soil nematodes

Post-fire recovery of Puya raimondii, vegetation and birds in the puna of huascarán National Park, Perú

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Journal of mountain science 2024年第1期21卷 20-32页

作者： mery l.sUNI Giovana P.VADIllO césar ARANA enoc JARA-PeNA letty sAlINAs m.estela PONce Paul m.RAmsAY Plant Physiology laboratory Faculty of Biological SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Natural history museum Universidad Nacional Mayor de San MarcosLima 15072Peru Applied Phytology laboratory Faculty of Biological SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Department of statistics Faculty of Mathematical SciencesUniversidad Nacional Mayor de San MarcosLima 15081Peru Department of chemical and Biological sciences Universidad de las Américas PueblaSan Andrés Cholula CP Cholula CP 72810Mexico

A large fire of 233 ha in huascarán National Park in Peru provided an opportunity to compare plant and bird responses in burned and nearby unburned zones of the puna. heights and live diameters of flagship Puya raimondii rosettes(assigned to four broad developmental phases), plant communities(66 species in 24 families and nine growth forms) and bird communities(77 species in six trophic guilds) were monitored after the fire. Although no mortality was observed, Puya raimondii plants were affected by the fire, losing approximately 60% of their photosynthetic area across all developmental phases, but recovered quickly during the first two years after fire. The comparison of Puya rosette recovery after fire was complicated by the changes in live rosette diameter for unburned plants, which showed plasticity of photosynthetic area linked to seasonal and annual fluctuations in precipitation in this relatively dry environment(decreased by 26% for mature adult plants over the study period). Fire caused an immediate change in the density, biomass and composition of vegetation. Although the species present remained similar, their abundances changed significantly immediately after the fire, with notable reductions in dominant tussock grasses. This provided opportunities for other plants, resulting in higher postfire diversity of plant species, genera, families and growth forms. In turn, the changes in vegetation after fire affected the composition of birds according to their trophic guild. Granivores largely disappeared,generalists were mostly unaffected, and other guilds showed a more complex response. As the vegetation recovered, most displaced birds returned within approximately one year.

关键词： Burning Plant biomass Trophic guilds Andes Giant rosette plants

Antibacterial hA-coatings on bioresorbable mg alloy

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Journal of magnesium and Alloys 2024年第5期12卷 1965-1985页

作者： K.V.Nadaraia D.V.mashtalyar m.A.Piatkova A.I.Pleshkova I.m.Imshinetskiy m.s.Gerasimenko e.A.Belov V.V.Kumeiko D.N.Kozyrev K.A.Fomenko V.V.mostovaya B.R.Torpanov A.R.Biktimirov I.s.Osmushko s.l.sinebryukhov s.V.Gnedenkov Institute of chemistry FeB RAs 159 Pr.100-letiya VladivostokaVladivostok 690022Russia Far eastern Federal University 10 Ajax BayRussky IslandVladivostok 690922Russia A.V.Zhirmunsky National scientific center of marine Biology FeB RAs 17 St.PalchevskogoVladivostok 690041Russia Regional clinical Dermatovenerological Dispensary 18 V St.GamarnikaVladivostok 690033Russia NmIc“Treatment and Rehabilitation center” 3 Ivankovskoe highwayMoscow 125367Russia

In this study,a calcium-phosphate coating was formed on a mg-mn-ce alloy by the plasma electrolytic oxidation(PeO).The antibiotic vancomycin,widely used in the treatment of infections caused by staphylococcus aureus(***),was impregnated into the *** with vancomycin showed high bactericidal activity against *** mechanical and electrochemical properties of the formed coatings were studied,as well as in vitro cytotoxicity tests and in vivo tests on mature male rats were *** to sem,eDs,XRD and XPs data,coatings had a developed morphology and contained hydroxyapatite,which indicates high *** analysis of roughness of coatings without and with vancomycin did not reveal any differences,confirming the high roughness of the *** electrochemical tests,an increase in corrosion resistance by more than two times after the application of PeO coatings was *** to the results of an in vivo study,after 28 days of the implantation of samples with calcium phosphate PeO coating and vancomycin,no signs of inflammation were observed,while an inflammatory reaction developed in the area of implantation of bare alloy,followed by *** release tests from the coatings show a sharp decrease in the concentration of the released antibiotic on day 7 and then a gradual decrease until day *** the experiment,no significant deviations in the condition and behavior of the animals were observed;clinical tests did not reveal a systemic toxic reaction.

关键词： Bioactive coatings Biocompatibility mg alloy Plasma electrolytic oxidation hydroxyapatite Vancomycin

Development of an ultrathin liquid sheet target for laser ion acceleration at high repetition rates in the kilohertz range

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high Power laser science and engineering 2024年第3期12卷 134-145页

作者： m.Füle A.P.Kovács T.Gilinger m.Karnok P.Gaál s.Figul G.marowsky K.Osvay National laser-Initiated Transmutation laboratory University of SzegedSzegedHungary Department of experimental Physics University of SzegedSzegedHungary elI AlPs ELI-HU Non-Profit Ltd.SzegedHungary Department of Optics and Quantum electronics University of SzegedSzegedHungary Advanced microfluidic systems Gmbh GöttingenGermany

A colliding microjet liquid sheet target system was developed and tested for pairs of round nozzles of 10,11 and 18μm in *** sheet's position stability was found to be better than a few *** interaction with 50 mJ laser pulses,the 18μm jet has a resonance amplitude of 16μm at a repetition rate of 33 hz,while towards 100 hz it converges to 10μm for all nozzles.A white-light interferometric system was developed to measure the liquid sheet thickness in the target chamber both in air and in vacuum,with a measurement range of 182 nm±1μm and an accuracy of±3%.The overall shape and 3D shape of the sheet follow the hasson±Peck model in *** vacuum versus air,the sheet gradually loses 10%of its thickness,so the thinnest sheet achieved was below 200 nm at a vacuum level of 10±4mbar,and remained stable for several hours of operation.

关键词： diagnostics laser ion acceleration nanometric liquid sheet targets vacuum test