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Heat transfer analysis of MHD and electroosmotic flow of non-Newtonian fluid in a rotating microfluidic channel:an exact solution

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Applied Mathematics and Mechanics(English Edition) 2021年第7期42卷 1047-1062页

作者： T.sIVA s.jangili B.KUMBHAKAR Department of Mathematics National Institute of Technology MeghalayaShillong 793003India Department of Mathematics National Institute of Technology WarangalTelangana 506004India

The heat transfer of the combined magnetohydrodynamic(MHD)and electroosmotic flow(EOF)of non-Newtonian fluid in a rotating microchannel is analyzed.A couple stress fluid model is scrutinized to simulate the rheological characteristics of the *** exact solution for the energy transport equation is ***,this solution is utilized to obtain the flow velocity and volume flow rates within the flow domain under appropriate boundary *** obtained analytical solution results are compared with the previous data in the literature,and good agreement is obtained.A detailed parametric study of the effects of several factors,e.g.,the rotational Reynolds number,the Joule heating parameter,the couple stress parameter,the Hartmann number,and the buoyancy parameter,on the flow velocities and temperature is *** is unveiled that the elevation in a couple stress parameter enhances the EOF velocity in the axial direction.

关键词： microfluidic electric double layer(EDL) electroosmotic flow(EOF) magnetohydrodynamic(MHD) couple stress fluid

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Ultrasound activatable antiangiogenic sonosensitizer for VEGFR associated glioblastoma tumor models

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Aggregate 2021年第4期2卷 137-143页

作者： subin son Chuangli Zhang Miae Won Paramesh jangili Minhyeok Choi Jiasheng Wu Jong seung Kim Department of Chemistry Korea UniversitySeoulKorea Key Laboratory of Photochemical Conversion and Optoelectronic Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijingChina

Angiogenic signaling pathway is a major contributing factor in cancer recurrence and progression,which can cause significantly reduced treatment outcomes,especially in the oxygen-dependent photo-and sonodynamic *** and its receptor(VEGFR)play a crucial role in angiogenesis progression;precisely,upregulated VEGF signaling ismainly associated with angiogenesis progression in many types of ***,we report a sunitinib-conjugated sonosensitizer(TK-RB:tyrosine kinase-rose bengal)to enhance the anticancer efficacy through VEGF inhibitionmediated antiangiogenesis in conjunction with cellular/tumor damage by ROs generated under ultrasound ***-RB reveals good selectivity and cytotoxicity toward VEGFR-positive cells(U87MG)over VEGFR-negative cells(MCF-7).The fluorescent imaging analysis in vivo/ex vivo and the tumor growth investigation in nude mice with U87MG glioblastoma tumor xenografts demonstrate that rose bengal having tyrosine kinase inhibitor(TK-RB)provides an enhanced antitumor *** current strategy will make a great contribution to optimizing anticancer performance by utilizing sonodynamic therapy together with antiangiogenics in several different malignancies.

关键词： antiangiogenesis glioblastoma sonodynamic therapy VEGFR blockage

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